what drug class is lovenox

Precautions

Prevents blood clots. Lovenox (Enoxaparin) is a good anticoagulant that reduces the risk of death or bleeding, and blood clots are less likely to happen. However, it is only available as an injection which isn't great if you're afraid of needles.

Why Lovenox instead of Coumadin?

Lovenox is an injectable anticoagulant, or blood thinner. It is also classified as a low molecular weight heparin. Lovenox is available in concentrations of 100 mg/ml and 150 mg/ml. When should you not give Lovenox? You should not use Lovenox if you are allergic to enoxaparin, heparin, benzyl alcohol, or pork products, or if you have:

Is Lovenox an anticoagulant or antiplatelet?

Upsides

• It is only available as an injection, so it's not great if you're afraid of needles.
• While surprise bleeding episodes can be treated while taking Lovenox (Enoxaparin), they won't completely work.
• It doesn't work as well as other medications for "thinning the blood" if you are overweight, underweight, or if you have kidney disease.

How effective is Lovenox?

Lovenox, or enoxaparin, is an anticoagulant (blood thinner) frequently prescribed for patients who are experiencing blood clots or are at higher risk of experiencing them in the future. One of the most common times that Lovenox is prescribed is when someone is recovering from surgery, which can increase the chances of a blood clot.

What is Lovenox prescribed for?

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What type of anticoagulant is Lovenox?

Lovenox is a blood thinner known as a low molecular weight heparin (LMWH). LMWHs are made from heparin. In a laboratory, heparin is chemically changed to become Lovenox. These changes allow Lovenox to have a more predictable and longer-lasting effect in the body.

What drug class is enoxaparin in?

Enoxaparin is in a class of medications called low molecular weight heparins. It works by stopping the formation of substances that cause clots.

Is Lovenox an anticoagulant or antiplatelet?

What is Lovenox? Lovenox (enoxaparin sodium) Injection is an anticoagulant (blood thinner) used to prevent blood clots that are sometimes called deep vein thrombosis (DVT), which can lead to blood clots in the lungs.

What is the action of Lovenox?

Lovenox's mechanism of action Lovenox is a blood thinner containing a low molecular weight heparin. The drug binds and accelerates the activity of antithrombin III, an enzyme which causes blood to clot by acting on a blood protein called fibrinogen. It also inhibits coagulation factors Xa and IIa.

Is enoxaparin a thrombolytic?

CII of enoxaparin is as safe as subcutaneous administration and can be safely used for both thrombolysis and prophylaxis in hospitalized patients with a wide range of thrombotic conditions.

Is Lovenox an anticoagulant?

Enoxaparin (Lovenox) is an anticoagulant medicine. It is one of a class of anticoagulants called low molecular weight heparin. Many people call these medicines blood thinners. They don't actually thin the blood, but they increase the time it takes a blood clot to form.

What is difference between antiplatelet and anticoagulant?

Anticoagulants, such as heparin or warfarin (also called Coumadin), slow down your body's process of making clots. Antiplatelets, such as aspirin and clopidogrel, prevent blood cells called platelets from clumping together to form a clot. Antiplatelets are mainly taken by people who have had a heart attack or stroke.

What are 3 types of anticoagulants?

There are three main types of anticoagulant medications: Vitamin K antagonists. Direct Oral Anticoagulants (DOACs) Low molecular weight heparins (LMWH)

What is the difference between an anticoagulant and a blood thinner?

Anticoagulants work by interrupting the process involved in the formation of blood clots. They're sometimes called "blood-thinning" medicines, although they don't actually make the blood thinner.

What should you not take with Lovenox?

You should tell your doctor if you are taking any other medications or supplements that thin your blood such as aspirin, ibuprofen, naproxen, garlic, ginger, ginkgo or ginseng. It is also recommended that you not take Lovenox if you are allergic to pork products, or enoxaparin, heparin or benzyl alcohol.

Is Lovenox a high risk medication?

Although it is generally a safe medication, Lovenox can cause serious injury and complications if used incorrectly. If Lovenox is given in too high of a dose, there is an increased risk of bleeding and adverse effects. Lovenox should only be used with a prescription and appropriate guidance from a healthcare provider.

What are side effects of Lovenox?

Common side effects of Lovenox include:nausea,diarrhea,fever,swelling in your hands or feet, or.injection site reactions (swelling, pain, bruising, or redness).

What is the drug enoxaparin used for?

Enoxaparin injection is used to prevent deep venous thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs. These blood clots can travel to the lungs and can become lodged in the blood vessels of the lungs, causing a condition called pulmonary embolism.

What are the anti clotting drugs?

There are many anticoagulants, including:heparin.warfarin (Coumadin)rivaroxaban (Xarelto)dabigatran (Pradaxa)apixaban (Eliquis)edoxaban (Savaysa)enoxaparin (Lovenox)fondaparinux (Arixtra)

What is another name for enoxaparin?

Enoxaparin is the generic name of Lovenox. The Food and Drug Administration (FDA) has approved two generic versions of Lovenox, which can be substituted for Lovenox. Enoxaparin and Lovenox are available as: Preservative-free, prefilled syringes that can be used one time.

Does Lovenox (enoxaparin) dissolve clots?

Lovenox (enoxaparin) does not dissolve or break up blood clots in the body. Instead, it prevents existing blood clots from getting bigger or becomi...

How long does it take Lovenox (enoxaparin) to work?

After an injection of Lovenox (enoxaparin), it takes a few hours to reach acceptable levels in the body. So it works fairly quickly when used to pr...

What foods should you avoid if you are on Lovenox (enoxaparin)?

Lovenox (enoxaparin) doesn't typically interact with food, so you don't need to change your diet to take this medication safely. It's always a good...

Is Lovenox (enoxaparin) a heparin?

Lovenox (enoxaparin) belongs to a class of anticoagulants called low molecular weight heparins (LMWH). In some ways, Lovenox (enoxaparin) and hepar...

How long do you stay on Lovenox (enoxaparin)?

Lovenox (enoxaparin) is recommended for various lengths of time, depending on the reason for use. Some people take it for a short period of time, e...

What is Lovenox used for?

Lovenox is indicated for: the inpatient treatment of acute deep vein thrombosis with or without pulmonary embolism, when administered in conjunction with warfarin sodium. the outpatient treatment of acute deep vein thrombosis without pulmonary embolism when administered in conjunction with warfarin sodium.

How long does Lovenox last?

When administered in conjunction with a thrombolytic (fibrin specific or non–fibrin specific), administer Lovenox between 15 minutes before and 30 minutes after the start of fibrinolytic therapy. The usual duration of Lovenox therapy is 8 days or until hospital discharge.

How long after taking Lovenox can you remove a catheter?

Placement or removal of a catheter should be delayed for at least 12 hours after administration of lower doses (30 mg once or twice daily or 40 mg once daily) of Lovenox and at least 24 hours after the administration of higher doses (0.75 mg/kg twice daily, 1 mg/kg twice daily, or 1.5 mg/kg once daily) of Lovenox.

How to administer Lovenox?

Position patients in a supine position for Lovenox administration by deep subcutaneous injection.

How much benzyl alcohol is in Lovenox?

The minimum amount of benzyl alcohol at which serious adverse reactions may occur is not known. Lovenox multiple-dose vials contain 15 mg/mL of benzyl alcohol (at the dose of 1.5 mg/kg twice a day, benzyl alcohol exposure in patients is 0.45 mg/kg daily) [see Warnings and Precautions (5.8)].

What medications should be discontinued prior to Lovenox?

These agents include medications such as: anticoagulants, platelet inhibitors including acetylsalicylic acid, salicylates, NSAIDs (including ketorolac tromethamine), dipyridamole, or sulfinpyrazone. If coadministration is essential, conduct close clinical and laboratory monitoring [see Warnings and Precautions (5.1)].

Where is enoxaparin metabolized?

Enoxaparin sodium is primarily metabolized in the liver by desulfation and/or depolymerization to lower molecular weight species with much reduced biological potency. Renal clearance of active fragments represents about 10% of the administered dose and total renal excretion of active and non-active fragments 40% of the dose.

What is Lovenox used for?

Uses for Lovenox. Enoxaparin is used to prevent deep venous thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs. These blood clots can travel to the lungs and can become lodged in the blood vessels of the lungs, causing a condition called pulmonary embolism.

How much does enoxaparin weigh?

However, elderly patients are more likely to have bleeding problems and age-related kidney disease, which may require an adjustment in the dose for patients receiving enoxaparin, especially those who weigh less than 45 kilograms (99 lb).

Can you inject enoxaparin at home?

If you are using enoxaparin at home, your doctor will teach you how to inject yourself with the medicine. Be sure to follow the directions carefully. Check with your doctor if you have any problems using the medicine.

Is enoxaparin safe for children?

Appropriate studies have not been performed on the relationship of age to the effects of enoxaparin in the pediatric population. Safety and efficacy have not been established .

Is Lovenox a heparin?

Lovenox. Medically reviewed by Drugs.com. Last updated on Dec 19, 2020. Epidural or spinal hematomas, which may result in long- term or permanent paralysis, may occur in patients who are anticoagulated with low molecular weight heparins or hepari noids and are receiving neuraxial anesthesia or undergoing spinal puncture.

What is Lovenox used for?

Lovenox is a prescription medicine used to prevent and treat the symptoms of blood clots ( Deep Vein Thrombosis or DVT) and chest pain ( angina ). Lovenox may be used alone or with other medications. Lovenox belongs to a class of drugs called Anticoagulants, Cardiovascular; Anticoagulants, Hematologic.

How many concentrations of Lovenox are there?

Lovenox is available in two concentrations (see Tables 26 and 27).

How long does Lovenox last?

When administered in conjunction with a thrombolytic (fibrin specific or non–fibrin specific), administer Lovenox between 15 minutes before and 30 minutes after the start of fibrinolytic therapy. The usual duration of Lovenox therapy is 8 days or until hospital discharge.

How is enoxaparin obtained?

Enoxaparin sodium is obtained by alkaline depolymerization of heparin benzyl ester derived from porcine intestinal mucosa. Its structure is characterized by a 2-O-sulfo-4-enepyranosuronic acid group at the non-reducing end and a 2-N,6-O-disulfo-D- glucosamine at the reducing end of the chain.

What medications should be discontinued prior to Lovenox?

These agents include medications such as: anticoagulants, platelet inhibitors including acetylsalicylic acid, salicylates, NSAIDs (including ketorolac tromethamine), dipyridamole, or sulfinpyrazone. If coadministration is essential, conduct close clinical and laboratory monitoring [see WARNINGS AND PRECAUTIONS ].

Where is enoxaparin metabolized?

Enoxaparin sodium is primarily metabolized in the liver by desulfation and/or depolymerization to lower molecular weight species with much reduced biological potency. Renal clearance of active fragments represents about 10% of the administered dose and total renal excretion of active and non-active fragments 40% of the dose.

Does Lovenox cause nausea?

The most common side effects of Lovenox include: nausea, diarrhea, anemia, confusion, and. pain, bruising, redness or irritation at the injection site. Tell the doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Lovenox.

What is Lovenox (enoxaparin)?

Lovenox (enoxaparin) is an anticoagulant (blood thinner) that works by blocking the activity of certain blood-clotting proteins. As a result, blood clots are less likely to form in your legs, lungs, heart, or other blood vessels. This lowers your risk of life-threatening conditions like pulmonary embolism or heart attack.

What are the side effects of Lovenox (enoxaparin)?

With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.

How much does Lovenox (enoxaparin) cost?

Lovenox (enoxaparin) is available as a generic medication and may be significantly cheaper compared to the brand version. Unless there is a specific reason you need the brand, the generic medication will be a better value. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price.

How long does it take for Lovenox to work?

After an injection of Lovenox (enoxaparin), it takes a few hours to reach acceptable levels in the body. So it works fairly quickly when used to prevent blood clots from forming. However, if you are using Lovenox (enoxaparin) to treat an existing blood clot, that clot will typically take weeks to go away because the body needs to dissolve it. For example, people who start on Lovenox (enoxaparin) for a blood clot in the leg may continue to have pain or swelling for weeks or even months.

What happens if you fall while taking Lovenox?

This is especially true if you have a really bad headache or dizziness. Your provider may want to check you for a brain bleed.

Is Lovenox a heparin?

Lovenox (enoxaparin) belongs to a class of anticoagulants called low molecular weight heparins (LMWH). In some ways, Lovenox (enoxaparin) and heparin are similar because both medications affect blood-clotting proteins in order to thin the blood. However, Lovenox (enoxaparin) has a different structure that helps it to target a more specific type ...

Does Lovenox interact with food?

Lovenox (enoxaparin) doesn't typically interact with food, so you don't need to change your diet to take this medication safely. It's always a good idea to discuss your daily diet and eating habits with your provider at your appointments, though.

Active ingredients

Enoxaparin is a LMWH with a mean molecular weight of approximately 4,500 daltons, in which the antithrombotic and anticoagulant activities of standard heparin have been dissociated. The drug substance is the sodium salt and has a high anti-Xa activity.

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

Unique identifiers

This drug has been assigned below unique identifiers within the countries it is being marketed:

What is enoxaparin?

Enoxaparin is an anticoagulant that helps prevent the formation of blood clots.

What is the name of the drug that is used to treat a blood clot?

you take aspirin or an NSAID (nonsteroidal anti-inflammatory drug)--ibuprofen (Advil, Motrin ), naproxen (Aleve), diclofenac, indomethacin, meloxicam, and others; or. you are using a blood thinner ( warfarin, Coumadin) or other medicines to treat or prevent blood clots. Tell your doctor if you have ever had:

What other drugs will affect enoxaparin?

Tell your doctor about all your other medicines, especially other medicines to treat or prevent blood clots, such as:

How is enoxaparin injected?

Enoxaparin is injected under the skin, or as an infusion into a vein. A healthcare provider may teach you how to properly use the medication by yourself. Read and carefully follow any Instructions for Use provided with your medicine. Do not use enoxaparin if you don't understand all instructions for proper use.

Can you take enoxaparin if you are allergic to heparin?

You should not use enoxaparin if you are allergic to enoxaparin, heparin, benzyl alcohol, or pork products, or if you have:

Can you take enoxaparin while pregnant?

Tell your doctor if you are pregnant. If you use enoxaparin during pregnancy, make sure your doctor knows if you have a mechanical heart valve.

How long does Lovenox last?

When administered in conjunction with a thrombolytic (fibrin specific or non–fibrin specific), administer Lovenox between 15 minutes before and 30 minutes after the start of fibrinolytic therapy. The usual duration of Lovenox therapy is 8 days or until hospital discharge.

What syringe to use for Lovenox?

Use a tuberculin syringe or equivalent when using Lovenox multiple-dose vials to assure withdrawal of the appropriate volume of drug.

What is Lovenox prefilled syringe?

Lovenox prefilled syringes and graduated prefilled syringes are for single, one-time use only and are available with a system that shields the needle after injection.

How long before balloon inflation can you take Lovenox?

For patients managed with percutaneous coronary intervention (PCI), if the last Lovenox subcutaneous administration was given less than 8 hours before balloon inflation, no additional dosing is needed. If the last Lovenox subcutaneous administration was given more than 8 hours before balloon inflation, administer an intravenous bolus of 0.3 mg/kg of Lovenox [see Warnings and Precautions (5.2) ].

How to administer Lovenox?

Position patients in a supine position for Lovenox administration by deep subcutaneous injection.

Is Lovenox sterile?

Lovenox is a clear, colorless to pale yellow sterile solution , and as with other parenteral drug products, should be inspected visually for particulate matter and discoloration prior to administration.

Is PT adequate for Lovenox?

Prothrombin Time (PT) and Activated Partial Thromboplastin Time (aPTT) are not adequate for monitoring the anticoagulant effects of Lovenox.

Indications and Usage For Lovenox

Lovenox Dosage and Administration

Contraindications

Warnings and Precautions

Adverse Reactions

Drug Interactions

Use in Specific Populations

Overdosage

Lovenox Description

Lovenox - Clinical Pharmacology