Interactions
Letrozole Drug Interactions. A total of 110 drugs (656 brand and generic names) are known to interact with letrozole. 3 major drug interactions (6 brand and generic names) 93 moderate drug interactions (583 brand and generic names)
Warnings
Letrozole side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Common side effects may include: hot flashes, warmth or redness in your face or chest; headache, dizziness, weakness; bone pain, muscle or joint pain;
How many drug interactions are there with letrozole?
Letrozole (Includes Femara) ↔ osteoporosis. Use of letrozole tablets may cause decreases in bone mineral density (BMD). Caution should exercise when prescribing this agent to patients with a risk of fractures, such as the elderly and patients with osteoporosis. Consider bone mineral density monitoring in patients treated with letrozole.
What are the side effects of letrozole?
Avoid driving or hazardous activity until you know how letrozole will affect you. Your reactions could be impaired. This medicine can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry...
Does Femara interact with letrozole?
What should I avoid while taking letrozole?
Can I take other medicine with letrozole?
Letrozole has no known minor interactions with other drugs.
Can you take Tylenol with letrozole?
No interactions were found between letrozole and Tylenol.
Can I take antibiotics with letrozole?
No interactions were found between amoxicillin and letrozole. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
What does letrozole do to a woman's body?
It's a hormone therapy for breast cancer. These types of therapies stop estrogen from encouraging breast cancer cells to grow. More specifically, Femara is a type of hormone therapy called an aromatase inhibitor. It works by lowering the amount of estrogen your body makes.
What foods should be avoided when taking letrozole?
No, there aren't any specific foods you should avoid while you're taking letrozole. Food doesn't interact with letrozole. But it can impact some of side effects of the drug. For instance, if you have hot flashes or nausea with letrozole, you can try reducing the amount of spicy or rich foods you eat.
Is it better to take letrozole in the morning or at night?
You can take letrozole at whatever time of day you find easiest to remember, but try to take your doses at the same time of day each day. This will help you to remember to take letrozole regularly. Swallow the tablet with a drink of water.
Does letrozole make you pee more?
LESS COMMON SIDE EFFECTS Let your doctor know if you have pain or discomfort when urinating, if you urinate more frequently than normal, or if your urine is cloudy or foul-smelling. Drink lots of fluids if you think you may have an infection. Sometimes, women have irritated eyes or blurred vision when taking letrozole.
Does letrozole make tired?
Most people are given letrozole for 5 years, but some will take it for up to 10 years. Common side effects can be like menopause symptoms and include hot flushes, difficulty sleeping, tiredness and low mood.
Do you gain weight on letrozole?
Weight gain is one of the occasional side effects that can occur when taking letrozole but if you are finding it difficult to control then it may be worth getting in touch with your doctor to let them know.
What are the worst side effects of letrozole?
RareContinuing or severe nervousness.dizziness or lightheadedness.fast heartbeat.heart attack.pain in the chest, groin, or legs, especially the calves.severe and sudden, unexplained troubled breathing.severe, sudden headache.slurred speech.More items...•
What are the long term side effects of letrozole?
Side effects that are more likely to take a few months to develop and persist long term include:blood changes, such as decreases in white blood cell counts or platelets.edema (swelling that usually affects your hands, feet, legs, or arms)hair loss.high cholesterol.More items...•
How do I know if letrozole is working?
How will I know if Letrozole is working? You may be asked to have a blood test during the menstrual cycle in which you are taking Letrozole. We usually take this blood sample on day 21 of your menstrual cycle and measure levels of the female hormone called progesterone. A level of 30 nmol/L or more is a good result.
Does joint pain from letrozole go away?
When I eventually stop taking letrozole, will I regain some flexibility and be able to move more freely? A: For many people, joint pain and stiffness will settle over time when you stop taking hormone therapy.
Can I take ibuprofen with letrozole?
Interactions between your drugs No interactions were found between ibuprofen and letrozole.
Can I take Advil with letrozole?
Interactions between your drugs No interactions were found between Advil and letrozole.
Can I drink coffee while taking letrozole?
Also talk to your doctor if these symptoms first appear more than a few weeks after you start taking letrozole. difficulty sleeping – avoid caffeine (tea, coffee, cola and chocolate) in the afternoon and evening.
Severe Interactions
These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
Serious Interactions
These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
Moderate Interactions
These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
Severe Interactions
These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
Serious Interactions
These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
Moderate Interactions
These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
Is letrozole safe for osteoporosis?
Letrozole (applies to letrozole) osteoporosis. Moderate Potential Hazard, Moderate plausibility. Use of letrozole tablets may cause decreases in bone mineral density (BMD). Caution should exercise when prescribing this agent to patients with a risk of fractures, such as the elderly and patients with osteoporosis.
Can you modify letrozole dosage?
No dosage modification is recommended for patients with mild to moderate hepatic impairment , however, therapy with letrozole should be administered cautiously to patients with severe hepatic impairment.
Is letrozole a liver disease?
Letrozole (applies to letrozole) liver disease. Major Potential Hazard, Moderate plausibility. Letrozole is extensively metabolized by the liver. The pharmacokinetic disposition of letrozole has not been assessed in patients with severe hepatic impairment.
How should I take letrozole?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
What is letrozole?
Letrozole lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.
How long after letrozole can you use birth control?
Use effective birth control if you are not past menopause. Keep using birth control for at least 3 weeks after your last dose of letrozole. Tell your doctor if you think you may be pregnant. Tell your doctor if you have ever had: liver disease (especially cirrhosis );
Can you breastfeed while taking Letrozole?
liver disease (especially cirrhosis ); osteoporosis, osteopenia (low bone mineral density); high cholesterol; or. if you also take tamoxifen. You should not breastfeed while you are using letrozole and for at least 3 weeks after your last dose.
How many interactions are there with Femara?
There are 3 disease interactions with Femara (letrozole):
Is letrozole bad for you?
Moderate Potential Hazard, Moderate plausibility. Use of letrozole tablets may cause decreases in bone mineral density (BMD). Caution should exercise when prescribing this agent to patients with a risk of fractures, such as the elderly and patients with osteoporosis.
Can letrozole be used for hepatic impairment?
No dosage modification is recommended for patients with mild to moderate hepatic impairment, however, therapy with letrozole should be administered cautiously to patients with severe hepatic impairment.
More About Letrozole
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
Clinical Trials Accepting Patients
Find Clinical Trials for Letrozole - Check for trials from NCI's list of cancer clinical trials now accepting patients.