Precautions
What are the side effects of alfuzosin? Alfuzosin side effects. a light-headed feeling, like you might pass out; new or worsening chest pain; upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or.
What are the side effects of using alfuzosin?
- tiredness
- headache
- runny or stuffy nose
- pain
- stomach pain
- heartburn
- constipation
- nausea
- decrease in sexual ability
- sore throat, fever, chills, cough and other signs of infection
What is the best time to take alfuzosin?
How to take alfuzosin
- Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. ...
- Take alfuzosin exactly as your doctor tells you to. ...
- Your first dose of alfuzosin may make you feel dizzy or faint, so it is important that you take it just before you go to bed. ...
What time of Day should I take alfuzosin?
Alfuzosin side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; new or worsening chest pain;
What are the side effects of alfuzosin 10 mg?
Is there a substitute for alfuzosin?
The selective agents, alfuzosin (Uroxatral), silodosin (Rapaflo), and tamsulosin (Flomax, generic), work primarily on the tissues of the urinary tract. The nonselective agents, doxazosin (Cardura, generic) and terazosin (Hytrin, generic), affect both the urinary tract and other tissues elsewhere in the body.
Is alfuzosin the same as Flomax?
Uroxatral (alfuzosin) is a good treatment for an enlarged prostate if medical treatment is needed. Flomax (tamsulosin) works just as well as similar medications but with fewer and less severe side effects. Helps make urinating easier. Available in generic.
How long should you take alfuzosin?
Conclusions: Alfuzosin 10 mg administered for 2 years in real practice is effective in improving LUTS and quality of life, and is well tolerated from a cardiovascular perspective, including in elderly men and those receiving antihypertensive co-medication.
Is Uroxatral the same as alfuzosin?
Uroxatral (alfuzosin hcl) is an alpha blocker prescribed to treat symptoms of an enlarged prostate (benign prostatic hyperplasia), which include painful or difficult urination, urination urgency or frequency. Uroxatral is available in generic form.
What is the safest medication for enlarged prostate?
Alpha blockers — which include alfuzosin (Uroxatral), doxazosin (Cardura), tamsulosin (Flomax) and silodosin (Rapaflo) — usually work quickly in men with relatively small prostates.
What is the best medication for enlarged prostate?
Alpha-blockers, such as tamsulosin (Flomax) or terazosin (Hytrin), which relax muscle tissue. 5-alpha reductase inhibitors, such as dutasteride (Avodart) and finasteride (Proscar), which shrink the prostate. A combination of the two, which, when used long-term, may help your symptoms more than either medicine alone.
Is alfuzosin safe long term?
Conclusions: Alfuzosin 10 mg o.d. provides effective relief from BPH, and clinical benefits are maintained up to 12 months. This study also demonstrates the satisfactory long-term safety of this formulation, and its safe use even in at-risk populations.
Which is better tamsulosin or alfuzosin?
Both treatments were well tolerated with respect to adverse events. Tamsulosin had no statistically significant effect on blood pressure compared with baseline but alfuzosin induced a significant reduction in both standing and supine blood pressure, compared with baseline (P < 0.05).
What are the long term side effects of alfuzosin?
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Belching.body aches or pain.congestion.cough producing mucus.decreased interest in sexual intercourse.difficulty breathing.difficulty having a bowel movement.More items...•
Does alfuzosin cause dementia?
In the unadjusted cohort, the incidence of dementia in the tamsulosin, doxazosin, terazosin, alfuzosin, and no-medication cohorts were 17.96%, 18.55%, 20.64%, 17.62%, and 22.60%, respectively.
Can you take Flomax and alfuzosin together?
Interactions between your drugs Using alfuzosin together with tamsulosin is not recommended. Combining these medications may cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position.
Can alfuzosin cause kidney problems?
However, elderly patients are more sensitive to the effects of this medicine than younger adults and are likely to have age-related kidney, liver, or heart problems, which may require caution in patients receiving alfuzosin.
Before Taking This Medicine
You should not take alfuzosin if you are allergic to it, or if you have: 1. moderate to severe liver disease.Some medicines can interact with alfuz...
How Should I Take Alfuzosin?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use t...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...
What Should I Avoid While Taking Alfuzosin?
This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.Drinking alcohol with thi...
Alfuzosin Dosing Information
Usual Adult Dose for Benign Prostatic Hyperplasia:Extended-release tablet: 10 mg orally once a day immediately after the same meal each day
What Other Drugs Will Affect Alfuzosin?
Many drugs can interact with alfuzosin, and some drugs should not be used together. This includes prescription and over-the-counter medicines, vita...
What is the name of the medicine that is similar to alfuzosin?
medicines similar to alfuzosin ( doxazosin, prazosin, silodosin, tamsulosin, or terazosin ). Tell your doctor if you have ever had: low blood pressure, especially if caused by taking medications; liver disease; kidney disease; prostate cancer; or. long QT syndrome (in you or a family member).
How to take alfuzosin?
Your doctor may occasionally change your dose. Use the medicine exactly as directed. Take alfuzosin just after a meal, at the same time each day. Do not take the medicine on an empty stomach.
What are the side effects of Alfuzosin?
Alfuzosin side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; new or worsening chest pain;
Can you take alfuzosin with cataract surgery?
Alfuzosin can affect your pupils. If you have cataract surgery, tell your surgeon ahead of time that you use alfuzosin. Alfuzosin is not for use in women, and the effects of this medicine during pregnancy or in breastfeeding women are unknown. Alfuzosin is not approved for use by anyone younger than 18 years old.
Can you take alfuzosin if you are allergic to it?
You should not take alfuzosin if you are allergic to it, or if you have: moderate to severe liver disease. Some medicines can cause unwanted or dangerous effects when used with alfuzosin. Your doctor may change your treatment plan if you also use: an antibiotic; antifungal medicine; heart medication;
Can you take alfuzosin with liver disease?
You should not take alfuzosin if you have moderate to severe liver disease. Many drugs can affect alfuzosin, and some should not be used at the same time. Tell your doctor about all your current medicines and any you start or stop using.
Can you crush Alfuzosin?
Swallow the tablet whole and do not crush, chew, or break it. Alfuzosin lowers blood pressure and may cause dizziness or fainting, especially when you first start taking it. You may feel very dizzy when you first wake up. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
How it works
Alfuzosin belongs to a class of drugs called alpha-blockers. It works by helping to relax muscles in your prostate and bladder. This can reduce your BPH symptoms and improve your ability to urinate.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
BPH and blood pressure drugs
Avoid using alfuzosin with other alpha-blockers. Combining the drugs may increase your risk of side effects since the medications work similarly. Examples of other alpha-blockers include:
Blood pressure drugs
Using blood pressure medications and alfuzosin together may increase your risk of low blood pressure, a sudden drop in your blood pressure when standing, or fainting. Examples of these drugs include:
Erectile dysfunction and pulmonary hypertension drugs
These include phosphodiesterase-5 (PDE-5) inhibitors. These drugs are used to treat erectile dysfunction and sometimes high blood pressure. Using them with alfuzosin may lead to very low blood pressure.
Drugs that inhibit CYP3A4 enzyme
The CYP3A4 enzyme processes alfuzosin in your liver. Medications that block this liver enzyme may cause the levels of alfuzosin to increase in your body. This may put you at risk for more side effects. Alfuzosin shouldn’t be used with strong inhibitors of this enzyme.
Warnings for people with certain health conditions
For people with liver problems: Don’t take alfuzosin if you have moderate or severe liver problems. If your liver isn’t working well, more of the drug may stay in your body. This increases your risk of side effects.
Can you take Zuclopenthixol and Acebutolol together?
Zuclopenthixol. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Acebutolol.
Can elderly people take alfuzosin?
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alfuzosin in the elderly. However, elderly patients are more sensitive to the effects of this medicine than younger adults and are likely to have age-related kidney, liver, or heart problems, which may require caution in patients receiving alfuzosin.
Can alfuzosin be given to women?
Therefore, even though alfuzosin may lessen the problems caused by enlarged prostate now, surgery may still be needed in the future. This medicine is usually given only to men. It is not normally given to women or children.
Does alfuzosin help with urination?
This can cause problems with urinating, such as a need to urinate often, a weak stream when urinating, or a feeling of not being able to empty the bladder completely. Alfuzosin helps relax the muscles in the prostate and the opening of the bladder. This may help increase the flow of urine or decrease the symptoms.
What is Alfuzosin used for?
Alfuzosin hydrochloride extended-release tablets are used in adult men to treat the symptoms of benign prostatic hyperplasia (BPH). Alfuzosin hydrochloride extended-release tablets may help to relax the muscles in the prostate and the bladder which may lessen the symptoms of BPH and improve urine flow.
How much alfuzosin is in USP?
Each Alfuzosin hydrochloride extended-release tablet, USP contains 10 mg Alfuzosin hydrochloride, USP as the active ingredient. Alfuzosin hydrochloride is a white to almost white powder that melts at approximately 240°C. It is freely soluble in water, sparingly soluble in alcohol, and practically insoluble in dichloromethane.
How much Alfuzosin hydrochloride is used for BPH?
The pharmacokinetics of Alfuzosin hydrochloride extended-release tablets have been evaluated in adult healthy male volunteers after single and/or multiple administration with daily doses ranging from 7.5 mg to 30 mg, and in patients with BPH at doses from 7.5 mg to 15 mg.
How much Alfuzosin is needed for fasting?
The recommended dosage is one 10 mg Alfuzosin hydroch loride extended-release tablet once daily. The extent of absorption of Alfuzosin is 50% lower under fasting conditions. Therefore, Alfuzosin hydrochloride extended-release tablets should be taken with food and with the same meal each day. The tablets should not be chewed or crushed.
Can you take Alfuzosin for prostate cancer?
Prostate cancer needs a different treatment. Alfuzosin hydrochloride extended-release tablets are not for use in women or children. Some medicines called "alpha-blockers" are used to treat high blood pressure. Alfuzosin hydrochloride extended-release tablets are not for the treatment of high blood pressure.
Does alfuzosin relax prostate?
Blockade of these adrenoreceptors can cause smooth muscle in the bladder neck and prostate to relax, resulting in an improvement in urine flow and a reduction in symptoms of BPH.
Is alfuzosin teratogenic?
Data. Alfuzosin was not teratogenic, embryotoxic or fetotoxic in rats at plasma exposure levels (based on AUC of unbound drug) up to 1200 times (maternal oral dose of 250 mg/kg/day) the maximum recommended human dose (MRHD) of 10 mg.
What is Alfuzosin used for?
Alfuzosin hydrochloride extended-release tablets are used in adult men to treat the symptoms of benign prostatic hyperplasia (BPH). Alfuzosin hydrochloride extended-release tablets may help to relax the muscles in the prostate and the bladder which may lessen the symptoms of BPH and improve urine flow.
How much alfuzosin hydrochloride is given daily?
The pharmacokinetics of alfuzosin hydrochloride extended-release tablets have been evaluated in adult healthy male volunteers after single and/or multiple administration with daily doses ranging from 7.5 mg to 30 mg, and in patients with BPH at doses from 7.5 mg to 15 mg.
How much alfuzosin is needed for fasting?
The recommended dosage is one 10 mg alfuzosin hydrochloride extended-release tablet, USP once daily. The extent of absorption of alfuzosin is 50% lower under fasting conditions. Therefore, alfuzosin hydrochloride extended-release tablets, USP should be taken with food and with the same meal each day. The tablets should not be chewed or crushed.
Does alfuzosin relax prostate?
Blockade of these adrenoreceptors can cause smooth muscle in the bladder neck and prostate to relax, resulting in an improvement in urine flow and a reduction in symptoms of BPH.
Can alfuzosin hydrochloride be used with PDE5?
Caution is advised when alpha adrenergic antagonists, including alfuzosin hydrochloride extended-release tablets, are co administered with PDE5 inhibitors. Alpha adrenergic antagonists and PDE5 inhibitors are both vasodilators that can lower blood pressure. Concomitant use of these two drug classes can potentially cause symptomatic hypotension [see Warnings and Precautions (5.4)].
Can alfuzosin be used in combination with alfuzosin?
However, interactions may be expected, and alfuzosin hydrochloride extended-release tablets should not be used in combination with other alpha adrenergic antagonists [see Warnings and Precautions (5.4) ].
Can alfuzosin cause syncope?
As with other alpha adrenergic antagonists, there is a potential for syncope. Patients should be warned of the possible occurrence of such events and should avoid situations where injury could result should syncope occur. There may be an increased risk of hypotension/postural hypotension and syncope when taking alfuzosin hydrochloride extended-release tablets concomitantly with anti-hypertensive medication and nitrates. Care should be taken when alfuzosin hydrochloride extended-release tablets are administered to patients with symptomatic hypotension or patients who have had a hypotensive response to other medications.
What is a terazosin?
Terazosin (Hytrin) Terazosin, sold under brand name Hytrin, is also an alpha-blocker that treats symptoms of hypertension and enlarged prostate. Like other medications of this kind, Hytrin relaxes blood vessels and muscles in the prostate and bladder neck to make it easier for a man to urinate.
What is the name of the drug that is used to treat BPH?
Silodosin (Rapaflo) Silodosin, available under brand name Rapaflo, is a prescription medication that belongs to a class of alpha-blockers used for the treatment of BPH. It is only approved for the management of BPH and functions in the same way as other drugs in this class.
What is flomax used for?
Flomax is an alpha-blocker drug commonly prescribed to treat the symptoms of an enlarged prostate. Alpha-blockers work by relaxing the muscles around your urethra and your bladder sphincter. By holding them in a permanently relaxed state, it eases urination, (so long as the prostate is not too enlarged).
What is the name of the drug that helps with enlarged prostate?
Alfuzosin (Uroxatral) Alfuzosin, available under brand name Uroxatral, is an alpha-blocker prescribed to treat symptoms of an enlarged prostate. Just like other members of this class of drugs, Uroxatral functions by relaxing the muscles in the prostate and bladder neck to make it easier to urinate.
What is phosphodiesterase 5 used for?
Phosphodiesterase-5 inhibitors. Although phosphodiesterase-5 inhibitors are mainly used for the treatment of erectile dysfunction , they can also help men with an enlarged prostate. In some cases, they are used in combination with other drugs for BPH to address erectile dysfunction and other side effects.
Is doxazosin a drug?
Doxazosin is primarily used to treat symptoms of BPH in men. However, it is also used alone or in combination with other drugs to manage high blood pressure. Sold under brand names Cardura and Cardura XL [v], this drug comes in tablet form. It is available at a lower price, so this may be more suitable for men with limited budgets.
Is flomax a selective alpha blocker?
Flomax is, actually, considered a selective alpha-blocker because it targets the urinary tract specifically and has less of an impact on other muscles in the body. When discussing Flomax and other natural alternatives and medications for BPH, it is important to clarify one thing at the very beginning.
Is tamsulosin a receptor antagonist?
Tamsulosin is the first adrenoceptor antagonist that is selective for the alpha 1 A-subtype; this specificity may explain its lack of effect on blood pressure compared with alfuzosin, an agent that is not receptor subtype specific.
Is tamsulosin a selective adrenoceptor?
The European Tamsulosin Study Group. Tamsulosin is the first adrenoceptor antagonist that is selective for the alpha 1 A-subtype;
Does tamsulosin lower blood pressure?
Tamsulosin had no statistically significant effect on blood pressure compared with baseline but alfuzosin induced a significant reduction in both standing and supine blood pressure, compared with baseline (P < 0.05).
