Precautions
The common side effects of Depakote and Depakene include:
- nausea
- headache
- sleepiness
- vomiting
- weakness
- tremor
- dizziness
- stomach pain
- blurry vision
- double vision
What are the adverse reactions of Depakote?
USES 1-3
- Depakote Delayed-Release Tablets and Depakote ER are used to treat manic episodes associated with bipolar disorder.
- Depakote Delayed-Release Tablets and Depakote ER are also used to prevent migraine headaches in adults.
- DO NOT TAKE Depakote Delayed-Release Tablets and Depakote ER for the prevention of migraine headache if you are pregnant.
What are the benefits of Depakote?
What is the difference between valproic acid and Depakote? Valproic acid is metabolized more rapidly than divalproex sodium, which could explain the need for higher doses. However, even at higher doses, treatment with valproic acid is still less expensive than with divalproex sodium because of the difference in price.
What is the difference between valproic acid and Depakote?
Depakene (valproic acid) is indicated for use as sole and adjunctive therapy in the treatment of simple and complex absence seizures, and adjunctively in patients with multiple seizure types which include absence seizures.
Is Depakene valproic acid?
What is the purpose of depakene?
Why should antiepilepsy drugs not be discontinued?
How old do you have to be to get a sex license?
Can you take Depakote with other medications?
Can depakote cause liver damage?
Does valproate dissociate?
Is depakene safe for breastfeeding?
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About this website
Is Depakene and Depakote the same thing?
The biggest difference between Depakene and Depakote lies in how the body breaks them down. Depakene is made of valproic acid only. Depakote is made by combining valproic acid and sodium valproate (another similar chemical) in a lab.
What is another name for valproic?
Valproic acid Brand names: Belvo, Depakote, Dyzantil, Convulex, Syonell.
What is the generic name for Depakote?
Divalproex sodium is a stable coordination compound comprised of sodium valproate and valproic acid used to treat manic episodes associated with bipolar disorder, epilepsy, and migraine headaches. Divalproex sodium is available under the following different brand names: Depakote, Depakote ER, and Depakote Sprinkles.
What type of medication is Depakene?
Depakene (valproic acid) is an antiepileptic used to treat various types of seizure disorders. Depakene is sometimes used together with other seizure medications. Depakene is available in generic form.
What is the generic name of Depakene?
Valproic (val-PRO-ik) acid is the generic name (non-brand name) of a widely used type of seizure medicine. The brand-name form of valproic acid in the United States and Canada is Depakene.
Why was Depakene discontinued?
In 1999, Abbott was forced to discontinue a clinical trial of Depakote in the treatment of dementia due to an increased incidence of adverse events, including somnolence, dehydration and anorexia experienced by the elderly study participants administered Depakote.
What can replace Depakote?
Lamotrigine.Latuda.Seroquel.Abilify.Topiramate.Vraylar.
What other drugs are like Depakote?
Common mood stabilizers include:lithium.sodium valproate (Depakote)lamotrigine (Lamictal)topiramate (Topamax)gabapentin (Neurontin)
Is gabapentin and Depakote the same thing?
Neurontin (gabapentin) is an old seizure disorder medicine that is now used to treat nerve-related pain caused by different conditions. Treats and prevents seizures, and stabilizes mood. Depakote (divalproex) is good for long-term prevention of seizures, manic episodes in bipolar disorder, and migraines.
Has Depakene been discontinued?
All of the above formulations have been discontinued.
Is Depakene a mood stabilizer?
Valproate is a mood stabilizer medication that works in the brain. It is approved for the treatment of mania associated with bipolar disorder (also known as manic depression), seizures (epilepsy), and migraine headaches.
What is Depakene used to treat?
This medication is used to treat seizure disorders, mental/mood conditions (such as manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.
What is the brand name for valproate?
Valproate products include: valproate sodium (Depacon), divalproex sodium (Depakote, Depakote CP, and Depakote ER), valproic acid (Depakene and Stavzor), and their generics.
What is valproic used for?
Valproic acid is used to treat certain types of seizures (epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures.
Is valproic acid the same as lamotrigine?
Both valproic acid and lamotrigine are effective as first-line monotherapy for the treatment of newly diagnosed adults with idiopathic generalized tonic-clonic seizures but valproic acid is preferable to lamotrigine because of being more effective and safe.
Is valproic acid the same as Keppra?
valproic-acid (valproic acid) is good for treating certain types of seizures, but can cause weight change and hair loss. Prevents seizures. Keppra (levetiracetam) is effective for preventing seizures in people with epilepsy and has fewer drug interactions than its alternatives.
Depakene Dosage Guide - Drugs.com
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 1 Nov 2022), Cerner Multum™ (updated 25 Oct 2022), ASHP (updated 12 Oct 2022 ...
What is the name of the acid that is a carboxylic acid?
Depakene (valproic acid) is a carboxylic acid designated as 2-propylpentanoic acid. It is also known as dipropylacetic acid. Valproic acid has the following structure:
Why should valproate be reduced?
Due to a decrease in unbound clearance of valproate and possibly a greater sensitivity to somnolence in the elderly , the starting dose should be reduced in these patients. Dosage should be increased more slowly and with regular monitoring for fluid and nutritional intake, dehydration, somnolence, and other adverse reactions. Dose reductions or discontinuation of valproate should be considered in patients with decreased food or fluid intake and in patients with excessive somnolence. The ultimate therapeutic dose should be achieved on the basis of both tolerability and clinical response [see Warnings and Precautions (5.14), Use in Specific Populations (8.5), and Clinical Pharmacology (12.3)].
How does Valproate affect pregnancy?
Inform pregnant women and women of childbearing potential (including girls beginning the onset of puberty) that use of valproate during pregnancy increases the risk of birth defects, decreased IQ, and neurodevelopmental disorders in children who were exposed in utero. Advise women to use effective contraception while taking valproate. When appropriate, counsel these patients about alternative therapeutic options. This is particularly important when valproate use is considered for a condition not usually associated with permanent injury or death such as prophylaxis of migraine headache [see Contraindications ( 4 )]. Advise patients to read the Medication Guide, which appears as the last section of the labeling [see Warnings and Precautions (5.2, 5.3, 5.4) and Use in Specific Populations (8.1)].
How is valproate metabolized?
Valproate is metabolized almost entirely by the liver. In adult patients on monotherapy, 30-50% of an administered dose appears in urine as a glucuronide conjugate. Mitochondrial β-oxidation is the other major metabolic pathway, typically accounting for over 40% of the dose. Usually, less than 15-20% of the dose is eliminated by other oxidative mechanisms. Less than 3% of an administered dose is excreted unchanged in urine.
Can you give valproate to a woman?
Valproate should not be administered to a woman of childbearing potential unless other medications have failed to provide adequate symptom control or are otherwise unacceptable [see Warnings and Precautions (5.2, 5.3, 5.4), Use in Specific Populations (8.1), and Patient Counseling Information (17)].
Can you take Valproate while pregnant?
Because of the risk to the fetus of decreased IQ, neurodevelopmental disorders, neural tube defects, and other major congenital malformations, which may occur very early in pregnancy, valproate should not be used to treat women with epilepsy or bipolar disorder who are pregnant or who plan to become pregnant unless other medications have failed to provide adequate symptom control or are otherwise unacceptable. Valproate should not be administered to a woman of childbearing potential unless other medications have failed to provide adequate symptom control or are otherwise unacceptable [see Warnings and Precautions (5.2, 5.3, 5.4), Use in Specific Populations (8.1), and Patient Counseling Information (17)].
Is depakene a monotherapy?
Depakene (valproic acid) is indicated as monotherapy and adjunctive therapy in the treatment of patients with complex partial seizures that occur either in isolation or in association with other types of seizures. Depakene (valproic acid) is indicated for use as sole and adjunctive therapy in the treatment of simple and complex absence seizures, and adjunctively in patients with multiple seizure types which include absence seizures.
How long does it take for Depakene to cause liver problems?
Depakene oral. Rarely, this medication has caused serious (sometimes fatal) liver problems, usually within the first 6 months of starting treatment. Laboratory tests should be performed before you start treatment and periodically during treatment, especially within the first 6 months, to monitor this side effect.
Are you currently using Depakene oral?
This survey is being conducted by the WebMD marketing sciences department.
How does a syringe work?
It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.
What to tell your dentist before surgery?
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
What are the effects of a syringe?
Diarrhea, dizziness, drowsiness, hair loss, blurred/ double vision, change in menstrual periods, ringing in the ears, shakiness (tremor), unsteadiness, weight changes may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
What are the symptoms of liver problems?
Tell your doctor right away if you develop symptoms of liver problems or pancreatitis such as unusual tiredness, weakness, swelling of the face, stomach / abdominal pain, loss of appetite, dark urine, yellowing eyes / skin, or persistent nausea / vomiting.
How much can you save on prescriptions?
Save up to 80% on your prescriptions.
What are some things I need to know or do while I take Depakene?
Tell all of your health care providers that you take Depakene (valproic acid capsules). This includes your doctors, nurses, pharmacists, and dentists.
How is this medicine (Depakene) best taken?
Use Depakene (valproic acid capsules) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
What are some other side effects of Depakene?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
Can you take Depakene with valproic acid?
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Depakene (valproic acid capsules) with all of your drugs and health problems.
Can you be allergic to depakene?
If you are allergic to Depakene ( valproic acid capsules); any part of Depakene (valproic acid capsules); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
Is Depakene discontinued?
If you have any questions about Depakene (valproic acid capsules), please talk with the doctor, pharmacist, or other health care provider. The Depakene brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
How to use Depakene Solution
Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking valproate sodium and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Are you currently using Depakene Solution?
This survey is being conducted by the WebMD marketing sciences department.
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What is valproic acid used for?
Valproic acid is an antiepileptic drug which is preferably used by the health professionals to treat different types of seizures such as generalized tonic-clonic seizures, absence seizures, tonic, atonic and myoclonic seizures and partial seizures with or without secondary generalization.
What is the best medication for seizures?
Valproic acid is the drug of choice for absence seizures. It is an alternative or adjuvant drug for generalized tonic-clonic seizures, simple partial seizures and complex partial seizures.
How long can you drive with valproic acid?
Driving should be avoided until seizure-free for at least one year or more. Some drug interactions may take place when valproic acid is used simultaneously with some other drugs:
What is the recurrent tendency to spontaneous, intermittent, abnormal electrical activity in part of the brain, manifesting as?
Epilepsy is a recurrent tendency to spontaneous, intermittent, abnormal electrical activity in part of the brain, manifesting as seizures. 2/3rd cases of epilepsy are idiopathic, often familial.
How long can you be seizure free?
After assessing risks and benefits for the individual patient, withdrawal may be tried, if the patients meet these criteria: normal CNS examination, normal IQ, normal EEG prior to withdrawal, seizure-free for more than 2 years, and no juvenile myoclonic epilepsy.
What is FindATopDoc?
FindATopDoc is a trusted resource for patients to find the top doctors in their area. Be visible and accessible with your up to date contact information, certified patients reviews and online appointment booking functionality.
Why is prompt diagnosis important?
Prompt diagnosis of such medical emergency lessens the upcoming complications
What is the purpose of depakene?
to prevent migraine headaches. Depakene (solution and liquid capsules) and Depakote Sprinkle Capsules are prescription medicines used alone or with other medicines, to treat: complex partial seizures in adults and children 10 years of age and older.
Why should antiepilepsy drugs not be discontinued?
Antiepilepsy drugs should not be abruptly discontinued in patients in whom the drug is administered to prevent major seizures because of the strong possibility of precipitating status epilepticus with attendant hypoxia and threat to life.
How old do you have to be to get a sex license?
For adults and children 10 years of age or older.
Can you take Depakote with other medications?
Taking Depakote or Depakene with certain other medicines can cause side effects or affect how well they work.
Can depakote cause liver damage?
Depakote and Depakene can cause serious side effects, including: 1.Serious liver damage that can cause death, especially in children younger than 2 years old. The risk of getting this serious liver damage is more likely to happen within the first 6 months of treatment.
Does valproate dissociate?
Valproic acid dissociates to the valproate ion in the gastrointestinal tract. The mechanisms by which valproate exerts its therapeutic effects have not been established. It has been suggested that its activity in epilepsy is related to increased brain concentrations of gamma-aminobutyric acid (GABA).
Is depakene safe for breastfeeding?
The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for Depakene and any potential adverse effects on the breastfed infant from Depakene or from the underlying maternal condition.
