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Precautions
What is the most important information I should know about antipyrine and benzocaine otic?
What happens if I overdose?
What other drugs will affect antipyrine and benzocaine otic?
How to remove ear wax from ear?
What to do if you don't feel better with antipyrine?
What is the difference between antipyrine and benzocaine?
How to give ear drops to a child?
See 4 more
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What is antipyrine & benzocaine otic solution used for?
Antipyrine and benzocaine combination is used in the ear to help relieve the pain, swelling, and congestion of some ear infections. It will not cure the infection itself. An antibiotic will be needed to treat the infection. This medicine is also used to soften earwax so that the earwax can be washed away more easily.
What kind of drug is antipyrine benzocaine?
Antipyrine and benzocaine are in a class of medications called analgesics. The combination of antipyrine and benzocaine works by reducing pain and discomfort in the ear.
Why was antipyrine and benzocaine discontinued?
Why was antipyrine/benzocaine discontinued? Antipyrine/benzocaine was not shown to be safe and effective for ear pain. The FDA required that the medication be discontinued.
Is antipyrine and benzocaine an antibiotic?
Antipyrine and benzocaine otic (for use in the ears) is a combination medicine used to treat pain and swelling caused by ear infections. This medicine does not contain an antibiotic and will not treat an ear infection.
What is the best ear drops for ear infection?
Ciprofloxacin and dexamethasone combination ear drops is used to treat ear infections, such as acute otitis externa and acute otitis media. Otitis externa, also known as swimmer's ear, is an infection of the outer ear canal caused by bacteria.
When should you not use ear drops?
Whether for ear wax, ear pain, tinnitus or swimmer's ear, ear drops are generally safe, but take note. “Ear drops are safe as long as your eardrum is intact,” Dr. Coffman said. When there is a perforation in the eardrum, drops can get into the middle ear.
Is it OK to use expired ear drops?
Don't use expired ear drops, as they can be contaminated and cause infection.
Is antipyrine and benzocaine otic over-the-counter?
Antipyrine/benzocaine/phenylephrine is an over-the-counter (OTC) product used to relieve ear pain/congestion. Antipyrine/benzocaine/phenylephrine is available under the following different brand names: EarGesic and Otogesic.
Do ear drops go past eardrum?
If you are using the eardrops for a middle ear infection—Drop the medicine into the ear canal. Then, gently press the tragus of the ear (see the diagram in the Medication Guide) four times in a pumping motion. This will allow the drops to pass through the hole or tube in the eardrum and into the middle ear.
How long ear drops can be used?
Ear drops typically are used several times a day for 7–10 days. If swelling narrows the opening into the ear, the doctor may clean the ear and insert a sponge called a wick into the ear canal. It will carry ear drops into the ear more effectively.
How do you relieve pressure in your ear?
If your ears are plugged, try swallowing, yawning or chewing sugar-free gum to open your eustachian tubes. If this doesn't work, take a deep breath and try to blow out of your nose gently while pinching your nostrils closed and keeping your mouth shut. If you hear a popping noise, you know you have succeeded.
Can I use ear drops for ear pain?
Antipyrine and Benzocaine are analgesics. Analgesics are medicines that reduce pain, relieve out a fever and sometimes decrease inflammation. The ear drops that relieve out the ear pain contain these analgesics. Although it can relieve the earache by treating the infections, it should be used only three times a day.
What drug class is benzocaine?
Benzocaine belongs to a group of medicines known as topical local anesthetics.
What is the mechanism of action of benzocaine?
Benzocaine diffuses into nerve cells where it binds to sodium channels, preventing the channels from opening, and blocking the influx of sodium ions. Nerve cells unable to allow sodium into cells cannot depolarize and conduct nerve impulses.
Is benzocaine an antihistamine?
Benzocaine/pyrilamine/zinc oxide is a topical anesthetic, antihistamine, and skin protectant combination. It works by numbing the skin and reducing swelling.
Is antipyrine benzocaine available over-the-counter?
Antipyrine/benzocaine/phenylephrine is an over-the-counter (OTC) product used to relieve ear pain/congestion. Antipyrine/benzocaine/phenylephrine is available under the following different brand names: EarGesic and Otogesic.
What Is Antipyrine and Benzocaine Otic?
Antipyrine is a pain reliever.Benzocaine is a local anesthetic (numbing medicine).Antipyrine and benzocaine otic (for use in the ears) is a combina...
What Is The Most Important Information I Should Know About Antipyrine and Benzocaine Otic?
Medicinal use of this product to treat ear infections has not been approved by the FDA.You should not use this medicine if you have a hole in your...
What Should I Discuss With My Healthcare Provider Before Using Antipyrine and Benzocaine Otic?
You should not use this medicine if you are allergic to antipyrine or benzocaine, or if you have a hole in your ear drum (ruptured ear drum).It is...
How Should I Use Antipyrine and Benzocaine Otic?
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.Antipyrine a...
What Happens If I Miss A Dose?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to m...
What Happens If I Overdose?
An overdose of antipyrine and benzocaine otic is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-8...
What Should I Avoid While Using This medication?
Do not use the medicine in your eyes. Antipyrine and benzocaine otic is for use only in the ears.Do not use other ear drops unless your doctor has...
Antipyrine and Benzocaine Otic Side Effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.Ca...
Antipyrine and Benzocaine Otic Dosing Information
Usual Adult Dose for Otitis Media:Apply an amount of solution sufficient to fill the affected ear canal. every 1 to 2 hours as needed for pain reli...
What Other Drugs Will Affect Antipyrine and Benzocaine Otic?
It is not likely that other drugs you take orally or inject will have an effect on antipyrine and benzocaine used in the ears. But many drugs can i...
Alternative to Antipyrine/Benzocaine Otic - Student Doctor Network
Antipyrine/benzocaine is being D/Ced according to the FDA. Can someone recommend an alternative for hospital use? Thanks!
Drug Discontinuation: Benzocaine and Antipyrine (Auralgan) Otic Drops
Drug Discontinuation Communication: Benzocaine and Antipyrine (Auralgan) Otic Drops. Situation. Auralgan (benzocaine and antipyrine) otic drops are no longer manufactured.
Antipyrine And Benzocaine (Otic Route) - Mayo Clinic
Antipyrine and benzocaine combination is used in the ear to help relieve the pain, swelling, and congestion of some ear infections. It will not cure the infection itself. An antibiotic will be needed to treat the infection. This medicine is also used to soften earwax so that the earwax can be washed ...
Antipyrine And Benzocaine (Otic Route) - Mayo Clinic
Along with its needed effects, a medicine may cause some unwanted effects. The following side effects may mean that you are having an allergic reaction to the medicine. Stop using the medicine right away if any of them occur. Check with your doctor if any of the following effects continue or are ...
Antipyrine-Benzocaine Solution - Uses, Side Effects, and More
Find patient medical information for antipyrine-benzocaine otic (ear) on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
List of Otic anesthetics - Drugs.com
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 1 Nov 2022), Cerner Multum™ (updated 25 Oct 2022), ASHP (updated 11 Nov 2022 ...
How should this medicine be used?
When antipyrine and benzocaine is used to help in the removal of ear wax, it is usually used 3 times daily for 2-3 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use antipyrine and benzocaine otic exactly as directed.
What side effects can this medication cause?
Antipyrine and benzocaine otic may cause side effects. Call your doctor if you have any unusual problems while taking this medication.
How long after opening a bottle of antipyrine should you dispose of it?
Antipyrine and benzocaine otic should be disposed of 6 months after the bottle is opened. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet.
Why is antipyrine prescribed?
Why is this medication prescribed? Antipyrine and benzocaine otic is used to relieve ear pain and swelling caused by middle ear infections. It may be used along with antibiotics to treat an ear infection. It is also used to help remove a build up of ear wax in the ear.
How long should you keep antipyrine?
Do not freeze. Antipyrine and benzocaine otic should be disposed of 6 months after the bottle is opened.
What to do if someone swallows antipyrine?
If someone swallows antipyrine and benzocaine otic, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Where to use antipyrine and benzocaine?
Antipyrine and benzocaine otic is for use only in the ears.
What is the best medicine for ear infections?
Antipyrine and benzocaine combination is used in the ear to help relieve the pain, swelling, and congestion of some ear infections. It will not cure the infection itself. An antibiotic will be needed to treat the infection. Antipyrine and benzocaine is also used to soften earwax so that the earwax can be washed away more easily.
How long should you rinse ear drops after using antipyrine?
If you are using antipyrine and benzocaine to help remove earwax, the ear should be flushed with warm water after you have used antipyrine and benzocaine for 2 or 3 days.
What to do if you miss a dose of antipyrine?
If you miss a dose of antipyrine and benzocaine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
How to use antipyrine and benzocaine?
Proper use of antipyrine and benzocaine. You may warm the ear drops to body temperature (37 °C or 98.6 °F) by holding the bottle in your hand for a few minutes before applying the drops. To use: Lie down or tilt the head so that the affected ear faces up.
How to store a syringe?
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed.
Can antipyrine be used with benzocaine?
The presence of other medical problems may affect the use of antipyrine and benzocaine combination. Make sure you tell your doctor if:
Can you take antipyrine and benzocaine together?
Using antipyrine and benzocaine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Hyaluronidase. St John's Wort.
What is the medication for ear pain?
Antipyrine and benzocaine otic solution is a medication that is used for ear pain, specifically pain caused by acute otitis media (middle ear infections). This medication may also reduce inflammation in the ear. It is intended to be used at the same time as an approved antibiotic for the treatment of an ear infection.
Why should the ear be pulled back and up?
The ear should be pulled slightly back and up in order to straighten out the ear canal.
Does ear drops cause stinging?
Other side effects of this medication include burning or stinging when the ear drops or first applied. You should contact your healthcare provider if you experience any of the following side effects: ear discharge or drainage, new or worsening redness or the ear or a rash, increased ear pain.
Can antipyrine cause hives?
As with all medications, it is possible to have an allergic reaction to antipyrine and benzocaine otic solution. Signs of an allergic reaction include itching, redness, or hives. A serious allergic reaction may cause difficulty breathing, swelling or the face, mouth, lips or throat. If you have symptoms of a serious allergic reaction go to the emergency room or call 911 immediately.
Can you put antipyrine in your ear?
Antipyrine and benzocaine otic solution comes in liquid form, typically in a bottle with a dropper. It may be more comfortable and less likely to cause dizziness if it is warmed prior to being put into the ear. You can do this by either holding it in your hands for a few minutes or running the bottle under warm (not hot) water for a few minutes. Ear drops are best administered by a second person if possible.
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Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Who is John Carew?
John Carew, MD, is board-certified in otolaryngology-head and neck surgery. He is an adjunct assistant professor at Mount Sinai Medical Center and NYU Medical Center.
Are you currently using Antipyrine-Benzocaine Solution?
This survey is being conducted by the WebMD marketing sciences department.
What is the difference between benzocaine and antipyrine?
This product contains 2 main medications. Benzocaine is a topical anesthetic that helps to numb the pain. Antipyrine is an analgesic that helps to decrease the pain and inflammation. This product may also contain glycerin, which helps to soften the earwax, and/or zinc acetate, which helps to protect the skin.
How to get ear drops to roll in?
To help the drops roll into the ear of an adult, hold the earlobe up and back. In children, hold the earlobe down and back.
How long does it take for ear drops to remove ear wax?
If you are using this medication to help remove earwax, gently rinsing the ear with warm water or using a soft rubber bulb after 2 to 3 days of treatment may help remove any remaining earwax. Consult your doctor or pharmacist about the safe use of an ear bulb.
How to get rid of dizziness from ear drops?
To lower the risk of dizziness, hold the container in your hand for a few minutes to warm it. To apply ear drops, wash your hands first. To avoid contamination, do not touch the dropper tip or let it touch your ear or any other surface. Lie on your side or tilt the affected ear upward.
How to use ear drops for children?
In children, hold the earlobe down and back. Keep the head tilted for about 2 minutes, or insert a soft cotton plug if so directed. You may be instructed by your doctor to moisten the cotton plug with this medication. Repeat for the other ear if so directed. Do not rinse the dropper.
Can antibiotics be given with ear drops?
An antibiotic medication may sometimes be prescribed along with this medication if you also have an infection. To make sure that the right amount of medication is given, and to avoid touching the ear with the dropper, have another person insert the drops if possible. To lower the risk of dizziness, hold the container in your hand ...
How to straighten ear canal?
Lie down or tilt the head so that the affected ear faces up. Gently pull the earlobe up and back for adults (down and back for children) to straighten the ear canal. Drop the medicine into the ear canal. Keep the ear facing up for about 5 minutes to allow the medicine to coat the ear canal.
How to use ear drops for ear canal?
Proper Use. You may warm the ear drops to body temperature (37 °C or 98.6 °F) by holding the bottle in your hand for a few minutes before applying the drops. Lie down or tilt the head so that the affected ear faces up. Gently pull the earlobe up and back for adults (down and back for children) to straighten the ear canal.
How long does it take for ear drops to flush?
If you are using this medicine to help remove earwax, the ear should be flushed with warm water after you have used this medicine for 2 or 3 days. This is usually done by your doctor.
Can you rinse a ear dropper after using it?
To keep the medicine as germ-free as possible, do not touch the dropper to any surface (including the ear). Do not rinse the dropper after use. Wipe the tip of the dropper with a clean tissue and keep the container tightly closed.
What are the ingredients in a prescription otic?
Unapproved prescription otic drug products containing the following ingredients are covered by this action: benzocaine; benzocaine and antipyrine; benzocaine, antipyrine, and zinc acetate; benzocaine, chloroxylenol, and hydrocortisone; chloroxylenol and pramoxine; and. chloroxylenol, pramoxine, and hydrocortisone.
What is the most commonly prescribed otic drop within SHF affected by this decision?
Auralgan (benzocaine and antipyrine) is the most commonly prescribed otic drop within SHF affected by this decision. Currently, Seton pharmacies have diminished all inventory of Auralgan. Auralgan and similar products are no longer manufactured and wholesalers no longer stock these products.
What is the FDA's intent to take enforcement action against companies that manufacture and/or distribute certain unapproved prescription?
The FDA announced its intention to take enforcement action against companies that manufacture and/or distribute certain unapproved prescription ear drop products (known as otic products) labeled to relieve ear pain, infection, and inflammation.
What are the ingredients in ear drops?
The unapproved prescription ear drops contain active ingredients such as benzocaine and hydrocortisone, and have not been evaluated by the FDA for safety, effectiveness and quality.
Why are otics given to children?
Unapproved prescription otic drug products are frequently given to young children suffering from ear infections and other conditions that cause ear pain and swelling. Patients taking unapproved drugs may be at greater risk because there is no proven safety or effectiveness information.
What is the best treatment for ear pain?
Prescribers may consider systemic pain relief with acetaminophen, ibuprofen, and/or warm compress to the ear (s).
What is the dosage for antipyrine and benzocaine otic (Auralgan, Aurodex - discontinued)?
To clean earwax, 3 to 4 drops of antipyrine and benzocaine octic solution is placed into the ear canal three times a day for 2 to 3 days.
What is Aurodex used for?
Antipyrine and benzocaine otic (Auralgan, Aurodex) was a prescription ear medication used to treat middle ear infections. The FDA asked all manufacturers of antipyrine/benzocaine otic products to stop selling these products because they have not been proven to be safe and effective.
Why did the FDA stop selling Aurodex?
On July, 2, 2015 the FDA asked all manufacturers of antipyrine and benzocaine otic products (Auralgan and Aurodex brand names) to stop selling these products because they have not been proven to be safe and effective.
What is antipyrine used for?
Antipyrine/benzocaine is a combination product used for cleaning the ear canal and for treating middle ear infections. It reduces pressure, congestion, inflammation, pain, and discomfort in the ear.
How to report side effects of prescription drugs?
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
How cold should antipyrine be stored?
Antipyrine/benzocaine solution should be stored at room temperature, between 15 C and 30 C (59 F and 86 F).
Is antipyrine a local anesthetic?
Antipyrine has pain relieving effects while benzocaine is a local anesthetic (numbing agent). Local anesthetics are chemicals that interfere with the function of the nerves that sense pain. The FDA has not approved products containing antipyrine/benzocaine.
What is the most important information I should know about antipyrine and benzocaine otic?
Medicinal use of this product to treat ear infections has not been approved by the FDA.
What happens if I overdose?
An overdose of antipyrine and benzocaine otic is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.
What other drugs will affect antipyrine and benzocaine otic?
It is not likely that other drugs you take orally or inject will have an effect on antipyrine and benzocaine used in the ears. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
How to remove ear wax from ear?
To use the ear drops for ear wax removal, use antipyrine and benzocaine otic 3 times per day for up to 3 days. This will help loosen ear wax for removal. Follow your doctor's instructions about safely removing the wax from your ear. Do not touch the dropper tip or place it directly in your ear.
What to do if you don't feel better with antipyrine?
Call your doctor if your symptoms do not improve, or if they get worse while using antipyrine and benzocaine otic.
What is the difference between antipyrine and benzocaine?
Antipyrine is a pain reliever. Benzocaine is a local anesthetic (numbing medicine). Antipyrine and benzocaine otic (for use in the ears) is a combination medicine used to treat pain and swelling caused by ear infections. This medicine does not contain an antibiotic and will not treat an ear infection. Antipyrine and benzocaine otic is also used ...
How to give ear drops to a child?
Lie down or tilt your head with your ear facing upward. Open the ear canal by gently pulling your ear back, or pulling downward on the earlobe when giving this medicine to a child. Hold the dropper upside down over your ear and drop in enough medicine to fill the ear canal.
