
CENTRAGARD is a transdermal solution containing eprinomectin and praziquantel available in 0.3 mL and 0.9 mL unit applicators to treat cats from 1.8 lbs to 33 lbs. Each mL of CENTRAGARD contains 4 mg of eprinomectin and 83 mg of praziquantel, as well as the inactive ingredients (dimethyl isosorbide, glycerol formal, and butylated hydroxytoluene).
Full Answer
What is centragard for cats?
CENTRAGARD is a transdermal solution containing eprinomectin and praziquantel available in 0.3 mL and 0.9 mL unit applicators to treat cats from 1.8 lbs to 33 lbs. Each mL of CENTRAGARD contains 4 mg of eprinomectin and 83 mg of praziquantel, as well as the inactive ingredients (dimethyl isosorbide, glycerol formal, and butylated hydroxytoluene).
What are the ingredients in centragard?
Each mL of CENTRAGARD contains 4 mg of eprinomectin and 83 mg of praziquantel, as well as the inactive ingredients (dimethyl isosorbide, glycerol formal, and butylated hydroxytoluene). Eprinomectin belongs to the avermectin class of anthelmintics and is a mixture of homologous components referred to as eprinomectin B1a and B1b.
What are the side effects of centragard topical solution?
There are very few side effects when the drug is given a the usual dose. The following side effects have been reported with the use of Centragard™ Topical Solution: temporary hairloss and slight inflammation or scabs at or near the application site, vomiting, diarrhea, decreased appetite, lethargy, and itchiness.
Is centragard legal in the US?
Centragard Caution Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.

What is CENTRAGARD used for?
CENTRAGARD is also approved to treat and control three of the most common intestinal parasites of cats -- hookworms, roundworms, and tapeworms. It is the first, and only, product to protect against this spectrum of parasites in an easy-to-use transdermal formulation.
Is CENTRAGARD a prescription?
Centragard is a prescription medication that is applied topically once a month. It should not be used on kittens under 7 weeks old or cats or kittens weighing under 1.8 lbs.
How long does it take CENTRAGARD to work?
CENTRAGARD may be administered year round or at a minimum, should start 1 month before the cat's first expected exposure to mosquitoes and continuing at monthly intervals until at least one month after the cat's last exposure to mosquitoes.
Where do you apply CENTRAGARD?
To apply CENTRAGARD pull back the plunger of the unit applicator slightly and remove the cap. Part the hair in one spot on the midline of the neck between the base of the skull and the shoulder blades, place the tip of the unit applicator on the skin and apply the contents directly on the skin.
Does CENTRAGARD treat ear mites?
This versatile topical product has the widest range of protection of both internal and external parasites. In both cats and dogs, all 3 stages of the flea life cycle are effectively controlled,in addition to ear mites.
What happens if a cat licks CENTRAGARD?
Oral ingestion of CENTRAGARD may also result in hypersalivation, vomiting and/or lethargy. In margin of safety studies, transient neurological signs such as ataxia, disorientation, lethargy, and pupil dilation were observed in some cats. Correct application will minimize the occurrence of such events.
Do cats poop out worms after being dewormed?
Fortunately, the treatment for roundworms is safe, simple, and relatively inexpensive. The dead and dying roundworms pass into the stool after administration of the anthelmintic or deworming medication.
Are dried tapeworm segments harmful?
The most important thing to remember when detecting tape worms in your pet and in your house is that these tape worm segments, whether fresh or dry, also contain tape worm eggs. If these dried segments are ingested, it is possible to pass on the tape worm parasite.
How do I clean my house if my cat has worms?
Use newspapers or paper towels to clean up waste. Rinse the soiled area with hot water and detergent. Scrub away as much of the soiling as you can, blotting with towels. Use an enzymatic cleaner to remove stains and odours.
Can you use CENTRAGARD and frontline together?
Centragard comes in single-use applicators for simple administration. Needs to be combined with Frontline Gold to protect from Fleas and Ticks. Benefits: Protects your cat from heartworm disease • Treats and controls roundworms, tapeworms, and hookworms • Only one dose required per month • Easy to administer.
Does CENTRAGARD treat fleas?
Centragard Treatment Centragard is a product that came on the market in 2018. It's a transdermal or topical medication, which means it's absorbed through the skin, just like flea and tick medication. It's another complete dewormer and prevents roundworms, tapeworms, hookworms, and heartworms.
How do topical worm treatments work?
The active ingredients in Profender® are absorbed topically through your cat's skin, reaching the intestinal tract to kill and remove worms. Profender® removes the stress of pilling your cat. If you've ever tried to trick a cat into swallowing a pill, we feel your pain.
How long after deworming a cat are the worms gone?
Most deworming medications take around 3 days to work, but severe cases can take up to 9 days for the worms to be gone. Certain factors can alter this time, such as the type of worm infection, the type of medication used, and how bad the infection is.
What to expect after deworming cat?
Although side effects of dewormer medications are uncommon, some cats may have vomiting, diarrhea, loss of appetite, or increased salivation. These symptoms, if occurred, are usually seen within 24 hours of taking the medication and should spontaneously resolve.
How long does it take for tapeworm medicine to work in a cat?
These tabs require only a single administration to start working and effectively eliminate tapeworms within 3 weeks; although, some cats may require another 2-3 week period of treatment.
Can tapeworm eggs live in carpet?
The tapeworm eggs can live in the environment in grass and soil, carpets and dust, so it is hard to eliminate the process of infection as we cannot keep this permanently clean.
What is Centragard for cats?
CENTRAGARD is also approved to treat and control three of the most common intestinal parasites of cats -- hookworms, roundworms, and tapeworms. It is the first, and only, product to protect against this spectrum of parasites in an easy-to-use transdermal formulation.
Does Centragard cause vomiting?
CENTRAGARD (eprinomectin and praziquantel transdermal solution) is for topical use only. Side effects may include vomiting, loss of appetite, lethargy, and hair changes and skin reactions at the site of application. If ingested, hypersalivation, vomiting, and lethargy may be observed.
What is Centragard used for?
INDICATIONS. CENTRAGARD is indicated for the prevention of heartworm disease caused by Dirofilaria immitis , and for the treatment and control of roundworms (adult and fourth stage larval Toxocara cati ), hookworms (adult and fourth stage larval Ancylostoma tubaeforme ; adult Ancylostoma braziliense ), and tapeworms ...
How to apply Centragard?
To apply CENTRAGARD pull back the plunger of the unit applicator slightly and remove the cap. Part the hair in one spot on the midline of the neck between the base of the skull and the shoulder blades, place the tip of the unit applicator on the skin and apply the contents directly on the skin.
How much eprinomectin is in a ctrgard?
CENTRAGARD is dosed at a minimum of 0.055 mL/lb (0.12 mL/kg), which delivers a minimum dose of 0.23 mg/lb eprinomectin and 4.55 mg/lb praziquantel. Administer the entire contents of a CENTRAGARD unit applicator topically once a month as specified in the following table:
How much praziquantel is in Centragard?
Each mL of CENTRAGARD contains 4 mg of eprinomectin and 83 mg of praziquantel, as well as the inactive ingredients (dimethyl isosorbide, glycerol formal, and butylated hydroxytoluene). Eprinomectin belongs to the avermectin class of anthelmintics and is a mixture of homologous components referred to as eprinomectin B1a and B1b. Praziquantel is a pyrazinoisoquinoline anthelmintic.
How long does it take for a cat to get a CENTRAGARD?
CENTRAGARD may be administered year round or at a minimum, should start 1 month before the cat’s first expected exposure to mosquitoes and continuing at monthly intervals until at least one month after the cat’s last exposure to mosquitoes.
Does centragard cause hypersalivation?
When cats licked the application site after treatment, temporary excessive salivation was observed. Oral ingestion of CENTRAGARD may also result in hypersalivation, vomiting and/or lethargy. In margin of safety studies, transient neurological signs such as ataxia, disorientation, lethargy, and pupil dilation were observed in some cats. Correct application will minimize the occurrence of such events.
Can you administer Centragard to cats?
Do not administer orally. Cats may salivate excessively and vomit if CENTRAGARD is accidentally administered orally or is ingested through licking/grooming the application site (see ANIMAL SAFETY ). The safety of CENTRAGARD has not been tested in breeding, pregnant or lactating cats.
How does Centragard work?
When applied, Centragard absorbs through the skin and circulates into the bloodstream. Concentrations of eprinomectin and praziquantel, the active ingredients, in the tissue and bloodstream help prevent heartworm disease and treat and control other worms.
What is the most important thing I should know about Centragard?
Centragard is a prescription medication that is applied topically once a month. It should not be used on kittens under 7 weeks old or cats or kittens weighing under 1.8 lbs. When replacing another monthly heartworm preventive product in a heartworm prevention program, the first treatment with Centragard should be given within one month of the last dose of the former medication.
What should I discuss with my veterinarian before applying Centragard on my pet?
At the discretion of your veterinarian, cats older than 6 months of age may be tested to determine the presence of existing heartworm infection before treatment with Centragard. Tell your veterinarian if your cat is pregnant, lactating, or breeding. Let your veterinarian know if your pet has ever had an allergic reaction to the ingredients, eprinomectin or praziquantel.
What are the potential side effects of Centragard?
Side effects of Centragard can include vomiting, anorexia, lethargy, temporary clumping or spiking of the hair, and mild skin reaction.
What should I avoid while applying Centragard on my pet?
Avoid contact with the eyes or mouth. Apply Centragard onto the skin only.
How much does Centragard weigh?
It is a safe, monthly topical medication for cats and kittens 7 weeks of age or older and 1.8 lbs or more. Centragard comes in single-use applicators for simple administration. Centragard requires a prescription from your veterinarian. For: Cats and kittens (7 weeks of age or older, weighing 1.8 lbs or more) Benefits:
How old do cats have to be to get Centragard?
At the discretion of your veterinarian, cats older than 6 months of age may be tested to determine the presence of existing heartworm infection before treatment with Centragard. Tell your veterinarian if your cat is pregnant, lactating, or breeding. Let your veterinarian know if your pet has ever had an allergic reaction to the ingredients, eprinomectin or praziquantel.
CAUTION
Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.
DESCRIPTION
CENTRAGARD is a transdermal solution containing eprinomectin and praziquantel available in 0.3 mL and 0.9 mL unit applicators to treat cats from 1.8 lbs to 33 lbs. Each mL of CENTRAGARD contains 4 mg of eprinomectin and 83 mg of praziquantel, as well as the inactive ingredients (dimethyl isosorbide, glycerol formal, and butylated hydroxytoluene).
INDICATIONS
CENTRAGARD is indicated for the prevention of heartworm disease caused by Dirofilaria immitis, and for the treatment and control of roundworms (adult and fourth stage larval Toxocara cati ), hookworms (adult and fourth stage larval Ancylostoma tubaeforme; adult Ancylostoma braziliense ), and tapeworms (adult Dipylidium caninum and Echinococcus multilocularis) in cats and kittens 7 weeks of age and older and 1.8 lbs or greater..
DOSAGE AND ADMINISTRATION
CENTRAGARD is dosed at a minimum of 0.055 mL/lb (0.12 mL/kg), which delivers a minimum dose of 0.23 mg/lb eprinomectin and 4.55 mg/lb praziquantel. Administer the entire contents of a CENTRAGARD unit applicator topically once a month as specified in the following table:
HUMAN WARNING
Not for human use. Keep out of reach of children. Avoid contact with the application site for 5 hours following treatment. Wash hands after administering the product. If the product accidentally gets into the eyes, flush thoroughly with water.
PRECAUTIONS
Do not administer orally. Cats may salivate excessively and vomit if CENTRAGARD is accidentally administered orally or is ingested through licking/grooming the application site (see ANIMAL SAFETY ).
ADVERSE REACTIONS
In a well-controlled field study, emesis, anorexia, lethargy, temporary clumping or spiking of the hair, or mild, transient skin reactions (itching, hair loss) were reported. When cats licked the application site after treatment, temporary excessive salivation was observed.

Description
Indications
- CENTRAGARD is indicated for the prevention of heartworm disease caused by Dirofilaria immitis , and for the treatment and control of roundworms (adult and fourth stage larval Toxocara cati), hookworms (adult and fourth stage larval Ancylostoma tubaeforme ; adult Ancylostoma braziliense), and tapeworms (adult Dipylidium caninum and Echinococcus multilocularis) in cat…
Dosage and Administration
- CENTRAGARD is dosed at a minimum of 0.055 mL/lb (0.12 mL/kg), which delivers a minimum dose of 0.23 mg/lb eprinomectin and 4.55 mg/lb praziquantel. Administer the entire contents of a CENTRAGARD unit applicator topically once a month as specified in the following table: To apply CENTRAGARD pull back the plunger of the unit applicator slightly and remove the cap. Part the h…
Human Warning
- Not for human use. Keep out of reach of children. Avoid contact with the application site for 5 hours following treatment. Wash hands after administering the product. If the product accidentally gets into the eyes, flush thoroughly with water. In case of accidental ingestion, or if skin or eye irritation occurs, contact a poison control center or physician for treatment advice.
Precautions
- Do not administer orally. Cats may salivate excessively and vomit if CENTRAGARD is accidentally administered orally or is ingested through licking/grooming the application site (see ANIMAL SAFETY). The safety of CENTRAGARD has not been tested in breeding, pregnant or lactating cats. The safety of CENTRAGARD has not been tested in kittens less than 7-9 weeks of age or weighi…
Adverse Reactions
- In a well-controlled field study, emesis, anorexia, lethargy, temporary clumping or spiking of the hair, or mild, transient skin reactions (itching, hair loss) were reported. When cats licked the application site after treatment, temporary excessive salivation was observed. Oral ingestion of CENTRAGARD may also result in hypersalivation, vomiting and/or lethargy. In margin of safety st…
Information For Owner Or Person Treating Animal
- Echinococcus multilocularis is a tapeworm found in wild canids and domestic cats. E. multilocularis can infect humans and cause serious disease (alveolar hydatid disease). Owners of cats living in areas where E. multilocularis are endemic should be instructed on how to minimize their risk of exposure to this parasite, as well as their cat’s risk of exposure. Although ML-635 wa…