
Precautions
Cetacaine (benzocaine, aminobenzoate and tetracaine) Spray is indicated for use to control painor gagging. Cetacaine (benzocaine, aminobenzoate and tetracaine) in all forms is indicated to control pain and for use for surgical or endoscopic or other procedures in the ear, nose, mouth, pharynx, larynx, trachea, bronchi, and esophagus.
What is Cetacaine spray used for?
Cetacaine is produced by the company Cetylite Industries, Inc. and they provide Cetacaine in three forms: liquid, gel, and spray. Cetacaine is a benzocaine-based anesthetic that also contains other active ingredients that include butamben and tetracaine hydrochloride.
What is Cetacaine made of?
INDICATIONS. Cetacaine (benzocaine, aminobenzoate and tetracaine) in all forms is indicated to control pain and for use for surgical or endoscopic or other procedures in the ear, nose, mouth, pharynx, larynx, trachea, bronchi, and esophagus. It may also be used for vaginal or rectal procedures when feasible.
Can Cetacaine be used for oral surgery?
Cetacaine is used to numb an area before a procedure. Cetacaine may be given to you for other reasons. Talk to your doctor. If you are allergic to Cetacaine; any part of this medicine; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If the patient is a child younger than 2 years of age.
What should I know about Cetacaine before taking it?

What class of drug is Cetacaine?
Cetacaine belongs to a class of drugs called Anesthetics, Topical.
What type of anesthetic is Cetacaine?
Medical uses. Cetacaine is a benzocaine-based anesthetic that also contains other active ingredients that include butamben and tetracaine hydrochloride. The main use for this drug is to produce anesthesia to mucous membranes to numb and help control the pain in that area.
Does Cetacaine cause methemoglobinemia?
Many topical anesthetic sprays such as CETACAINE (benzocaine 14%, tetracaine 2%) and HURRICAINE (benzocaine 20%) have been implicated in cases of methemoglobinemia, a serious and sometimes fatal adverse drug reaction. Methemoglobinemia occurs when iron in hemoglobin is changed from its ferrous to its ferric form.
Is Cetacaine flammable?
May be harmful if swallowed. This product is a Non-Flammable liquid with a flash point of >200°F. Warning! Contents under pressure and may rupture when heated.
How long does Cetacaine topical last?
The onset of Cetacaine-produced anesthesia is rapid (approximately 30 seconds) and the duration of anesthesia is typically 30-60 minutes, when used as directed.
How do you use Cetacaine spray?
0:000:44Cetacaine Spray Demo - YouTubeYouTubeStart of suggested clipEnd of suggested clipOne second or less for normal anaesthesia spray in excess of two seconds is contraindicated.MoreOne second or less for normal anaesthesia spray in excess of two seconds is contraindicated. Anesthesia is produced within 30 seconds and duration is typically 30 to 60 minutes when used as directed.
How likely is it to get methemoglobinemia from Orajel?
The second most common dosage form was oral gel (n=20). Four cases resulted in death, including one infant and three adults. In 36 of the 119 cases (30 percent) the reported methemoglobin level was 30 to 55 percent, with the normal concentration typically around one to two percent.
What are the symptoms of methemoglobinemia?
What are the symptoms of methemoglobinemia?headache.shortness of breath.nausea.rapid heart rate.fatigue and lethargy.confusion or stupor.loss of consciousness.
Who is at risk of methemoglobinemia?
Acquired methemoglobinemia is more frequent in premature infants and infants younger than 4 months, and the following factors may have a role in the higher incidence in this age group: Fetal hemoglobin may oxidize more easily than adult hemoglobin.
Is Cetacaine an ester or amide?
Available in gel, spray and liquid forms, Cetacaine is a combination of three ester topical anesthetics, 2% tetracaine, 14% benzocaine and 2% butamben. It is not an FDA-approved drug, therefore, the MRD is unknown — but caution is indicated due to its tetracaine content and rapid absorption.
Is Cetacaine an OTC?
Rx only. Cetacaine is not for injection. Cetacaine is contraindicated in patients who are hypersensitive to anesthetics. Cetacaine should not be used in patients with congenital or idiopathic methemoglobinemia.
What is another name for etomidate?
EtomidateClinical dataTrade namesAmidate, Hypnomidate, TomviAHFS/Drugs.comMonographLicense dataUS DailyMed: EtomidateRoutes of administrationIntravenous29 more rows
What's better benzocaine or lidocaine?
Lidocaine and benzocaine were equally efficient, and both were better than placebo in reducing pain caused by insertion of needles into the palate.
What is cetacaine used for?
Cetacaine is used to numb an area before a procedure.
How is Cetacaine best taken?
Use Cetacaine as ordered by your doctor. Read all information given to you. Follow all instructions closely.
What are some other side effects of Cetacaine?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
How do I store and/or throw out Cetacaine?
If you need to store Cetacaine at home, talk with your doctor, nurse, or pharmacist about how to store it.
How old do you have to be to give Cetacaine?
If the patient is a child younger than 2 years of age. Do not give Cetacaine to a child younger than 2 years of age. Do not use Cetacaine for teething.
What to do if you have questions about cetacaine?
Check with your pharmacist. If you have any questions about Cetacaine, please talk with your doctor, nurse, pharmacist, or other health care provider.
Can cetacaine be swallowed?
This medicine may cause harm if swallowed. If Cetacaine is swallowed, call a doctor or poison control center right away.
What is a cetacaine spray?
Cetacaine (benzocaine, aminobenzoate and tetracaine) Spray is indicated for use to control pain or gagging. Cetacaine (benzocaine, aminobenzoate and tetracaine) in all forms is indicated to control pain and for use for surgical or endoscopic or other procedures in the ear, nose, mouth, pharynx, larynx, trachea, bronchi, and esophagus.
How long should you spray Cetacaine?
DOSAGE AND ADMINISTRATION. Cetacaine (benzocaine, aminobenzoate and tetracaine) Spray should be applied for approximately one second or less for normal anesthesia. Only a limited quantity of Cetacaine (benzocaine, aminobenzoate and tetracaine) is required for anesthesia. Spray in excess of two seconds is contraindicated.
How long does it take for Cetacaine to produce anesthesia?
The onset of Cetacaine (benzocaine, aminobenzoate and tetracaine) produced anesthesia is rapid (approximately 30 seconds) and the duration of anesthesia is typically 30-60 minutes, when used as directed.
Can you give tetracaine to a hypersensitive person?
Cetacaine (benzocaine, aminobenzoate and tetracaine) should not be administered to patients who are hypersensitive to any of its ingredients or to patients known to have cholinesterase deficiencies. Tolerance may vary with the status of the patient.
Can you inject Cetacaine?
Cetacaine (benzocaine, aminobenzoate and tetracaine) is not suitable and should never be used for injection. Do not use on the eyes. To avoid excessive systemic absorption, Cetacaine (benzocaine, aminobenzoate and tetracaine) should not be applied to large areas of denuded or inflamed tissue.
Is it safe to use Cetacaine?
Safe use of Cetacaine (ben zocaine, aminobenzoate and tetracaine) has not been established with respect to possible adverse effects upon fetal development. Therefore, Cetacaine (benzocaine, aminobenzoate and tetracaine) should not be used during early pregnancy, unless in the judgement of a physician, the potential benefits outweigh the unknown hazards. Routine precaution for the use of any topical anesthetic should be observed when Cetacaine (benzocaine, aminobenzoate and tetracaine) is used.
Can Cetacaine be used for rash?
If rash, urticaria, edema, or other manifestations of allergy develop during use, the drug should be discontinued. To minimize the possibility of a serious allergic reaction, Cetacaine (ben zocaine, aminobenzoate and tetracaine) preparations should not be applied for prolonged periods except under continual supervision.
What is cetacaine used for?
The main use for this drug is to produce anesthesia to mucous membranes to numb and help control the pain in that area. The spray form of Cetacaine is also used to help prevent gagging in the patient.
What is the active ingredient in cetacaine?
Cetacaine is an anesthetic that contains the active ingredients of benzocaine at 14%, butamben at 2%, and tetracaine hydrochloride at 2%. Cetacaine also contains small amounts of benzalkonium chloride at 0.5% and 0.005% of cetyl dimethyl ethyl ammonium bromide all in a bland water-soluble base. Although Cetacaine has been widely used in ...
How long does cetacaine last?
Cetacaine acts quickly in about 30 seconds and can last between 30–60 minutes. This is due to benzocaine causing the immediate anesthetic effect, while butamben and tetracaine hydrochloride causes the extended effect of Cetacaine.
How long does it take for Cetacaine to work?
The anesthetic effect of Cetacaine can be expected to take effect in about 30 seconds and last between 30–60 minutes depending on location and application amount. Cetacaine can and has been used for surgeries that include bronchi, ear, esophagus, larynx, mouth, nose, pharynx, rectal, and vaginal procedures.
How long should you spray cetacaine?
Spray: Cetacaine spray should be applied for only one second and dosage should not exceed an application spray longer than 2 seconds.
Where is Cetacaine made?
The company the makes Cetacaine is called Cetylite Industries, Inc. This company is based out of Pennsauken, NJ and has a total of 75 employees. Cetylite brings in total revenue of around $7,500,000 with their main product being the topical anesthetics, and infection prevention products.
When was benzocaine first used?
The marketing start date for Cetacaine was January 1, 1960, but benzocaine was first produced in 1890 by German scientist 1890 by Eduard Ritsert. Cetacaine is mainly used in the dental field but has seen use as well in the medical field when dealing with small surgeries on or around mucus membranes.
What is cetacaine spray?
Cetacaine is a topical anesthetic indicated for the production of anesthesia of all accessible mucous membrane except the eyes. Cetacaine Spray is indicated for use to control pain or gagging. Cetacaine in all forms is indicated to control pain and for use for surgical or endoscopic or other procedures in the ear, nose, mouth, pharynx, larynx, ...
How long should you spray cetacaine?
Cetacaine Spray should be applied for approximately one second or less for normal anesthesia. Only a limited quantity of Cetacaine is required for anesthesia. Spray in excess of two seconds is contraindicated. Each one-second spray contains an average of 200 mg of product, not including propellant.
What is the item number for Cetacaine Liquid Chairside Kit?
Cetacaine Liquid Syringes and Microcapillary Delivery Tips are supplied with the Cetacaine Liquid Chairside Kit (Item # 0218) and Clinical Kit (Item # 0212). They also can be purchased separately. Syringes are available in packs of 50 (Item # 0219S) or packs of 100 (Item # 0214). Delivery Tips are available in packs of 50 (Item # 0219T) or packs of 100 (Item # 0213).
How long does Cetacaine take to produce anesthesia?
The onset of Cetacaine-produced anesthesia is rapid (approximately 30 seconds) and the duration of anesthesia is typically 30-60 minutes, when used as directed. This effect is due to the rapid onset, but short duration of action of Benzocaine coupled with the slow onset, but extended duration of Tetracaine HCI and bridged by ...
Can Cetacaine cause rash?
Localized allergic reactions may occur after prolonged or repeated use of any aminobenzoate anesthetic. The most common adverse reaction caused by local anesthetics is contact dermatitis characterized by erythema and pruritus that may progress to vesiculation and oozing. This occurs most commonly in patients following prolonged self-medication, which is contraindicated. If rash, urticaria, edema, or other manifestations of allergy develop during use, the drug should be discontinued. To minimize the possibility of a serious allergic reaction, Cetacaine preparations should not be applied for prolonged periods except under continual supervision. Dehydration of the epithelium or an escharotic effect may also result from prolonged contact.
Can you use Cetacaine under a denture?
Cetacaine should not be used under dentures or cotton rolls, as retention of the active ingredients under a denture or cotton roll could possibly cause an escharotic effect. Routine precaution for the use of any topical anesthetic should be observed when using Cetacaine.
Does cetacaine spray have propellant leaks?
Cetacaine Spray contains CFC-114 and CFC-11, substances which harm public health and environment by destroying ozone in the upper atmosphere. The propellant leak rate of Cetacaine Spray does not meet the USP requirements.
How old do you have to be to use Cetacaine?
Do not use Cetacaine Spray or Cetacaine Liquid to treat infants or children younger than 2 years.
How long should you spray cetacaine?
Cetacaine Spray should be applied for approximately one second or less for normal anesthesia. Only a limited quantity of Cetacaine is required for anesthesia. Spray in excess of two seconds is contraindicated. Each one-second spray contains an average of 200 mg of product, not including propellant.
What is the item number for Cetacaine Liquid Chairside Kit?
Cetacaine Liquid Syringes and Microcapillary Delivery Tips are supplied with the Cetacaine Liquid Chairside Kit (Item # 0218) and Clinical Kit (Item # 0212). They also can be purchased separately. Syringes are available in packs of 50 (Item # 0219S) or packs of 100 (Item # 0214). Delivery Tips are available in packs of 50 (Item # 0219T) or packs of 100 (Item # 0213).
How to use Cetylite Luer-lock?
Caution: Do not over-tighten. Remove small cap from luer-lock port, retaining it for replacement after use. Port allows for a single dip of a cotton or brush applicator for application directly to accessible mucous membrane. For application into periodontal pockets, Cetylite Luer-lock syringes and Microcapillary Delivery Tips are recommended. Cetylite Syringes are clearly marked in (4) 0.1 mL increments. To fill, attach syringe to port by gently twisting clockwise until secure. Invert and draw desired amount of liquid into the syringe. Remove filled syringe and attach Microcapillary Delivery Tip to the syringe. Tip may be bent to improve access. Apply drop-wise to accessible mucous membrane (such as buccal and lingual sulcus) by slowly depressing the syringe plunger. Discard all applicators after use.
Can Cetacaine cause rash?
Localized allergic reactions may occur after prolonged or repeated use of any aminobenzoate anesthetic. The most common adverse reaction caused by local anesthetics is contact dermatitis characterized by erythema and pruritus that may progress to vesiculation and oozing. This occurs most commonly in patients following prolonged self-medication, which is contraindicated. If rash, urticaria, edema, or other manifestations of allergy develop during use, the drug should be discontinued. To minimize the possibility of a serious allergic reaction, Cetacaine preparations should not be applied for prolonged periods except under continual supervision. Dehydration of the epithelium or an escharotic effect may also result from prolonged contact.
Can you inject cetacaine in the eyes?
Cetacaine is not suitable and should never be used for injection. Do not use on the eyes. To avoid excessive systemic absorption, Cetacaine should not be applied to large areas of denuded or inflamed tissue. Cetacaine should not be administered to patients who are hypersensitive to any of its ingredients or to patients known to have cholinesterase deficiencies. Tolerance may vary with the status of the patient.
Is cetacaine spray safe for kids?
An appropriate pediatric dosage has not been established for Cetacaine Spray or Cetacaine Liquid.
How long does cetacaine last?
A quick 1-second spray Cetacaine Spray delivers a single dose of mild-banana-flavored Cetacaine, that lasts 30-60 minutes.
How many doses of cetacaine are in a 20g bottle?
The 20g bottle contains 42 one-second doses. Cetacaine Topical Anesthetic Spray is indicated for uses on all accessible mucosal membrane except the eyes. Rx only. Cetacaine is not for injection. Cetacaine is contraindicated in patients who are hypersensitive to anesthetics.
What is the best topical anesthetic for gag reflex?
Cetacaine is the only Rx topical anesthetic spray indicated for gag reflex suppression. Cetacaine’ s combination of active ingredients is proven more effective than Benzocaine alone*.
What is Cetacaine Liquid?
Cetacaine Liquid is available in both a 14g and 30 g bottle size and each bottle also includes a special luer-lock dispensing cap, used for filling luer-lock syringes with just amount of Cetacaine Liquid needed for treatment, reducing waste. For dental procedures, such as SRP, Cetacaine Liquid can be comfortably dispensed into periodontal pockets for up to 60 minutes of needle-free pain control. The viscous liquid is easy to control using Cetylite’s single-use Delivery Syringes and Tips (available separately) to a comfortably apply Cetacaine Liquid drop by drop into periodontal pockets, or by applying to the surface of mucous membrane with a cotton swab or microbrush. Cetacaine’s three active ingredient formula has been actively prescribed for professional use in dental and medical settings for more than 50 years, an assurance of its efficacy and Cetylite’s uncompromising commitment to patient safety and comfort. Rx only.
Is cetacaine a rx?
Rx only. Cetacaine is not for injection.
Can you use cetacaine in congenital patients?
Cetacaine should not be used in patients with congenital or idiopathic methemoglobinemia. Please refer to the full prescribing information under Resources to know more about Cetacaine. Cetacaine Liquid is also available in kits. Further Kit information can be found under related items below.
Can you use Cetacaine in periodontal pockets?
For dental procedures, such as SRP, Cetacaine Liquid can be comfortably dispensed into periodontal pockets for up to 60 minutes of needle-free pain control. The viscous liquid is easy to control using Cetylite’s single-use Delivery Syringes and Tips (available separately) to a comfortably apply Cetacaine Liquid drop by drop into periodontal ...

Overview
Ascorbic acid (vitamin C) is used to prevent or treat low levels of vitamin C in people who do not get enough of the vitamin from their diets.
Status: Discontinued
May Treat: Vitamin C deficiency
Alternate Brand Names: Cecon · Vitamin C
Drug Class: Vitamins - C, Ascorbic Acid and Derivatives
Availability: Prescription sometimes needed
Status: Discontinued
May Treat: Vitamin C deficiency
Alternate Brand Names: Cecon · Vitamin C
Drug Class: Vitamins - C, Ascorbic Acid and Derivatives
Availability: Prescription sometimes needed
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
Manufacturer: FOREST PHARMACE
Medical uses
Adverse effects
Pharmacology
Contraindications
Cetacaine is a topical anesthetic that contains the active ingredients benzocaine (14%), butamben (2%), and tetracaine hydrochloride (2%). Cetacaine also contains small amounts of benzalkonium chloride at 0.5% and 0.005% of cetyl dimethyl ethyl ammonium bromide all in a bland water-soluble base. Although Cetacaine has been widely used in the medical and dental fields, it has yet to be officially approved by the FDA. Cetacaine is produced by the company Cetylite Industries, I…
Interactions
Cetacaine is a benzocaine-based anesthetic that also contains other active ingredients that include butamben and tetracaine hydrochloride. The main use for this drug is to produce anesthesia to mucous membranes to numb and help control the pain in that area. The spray form of Cetacaine is also used to help prevent gagging in the patient. The anesthetic effect of Cetacaine can be expected to take effect in about 30 seconds and last between 30–60 minutes …
History
Cetacaine has been known to cause adverse effects in the patients it has been administered to. These include hypersensitivity in the form of anaphylaxis, dermatitis, erythema, pruritus which can lead to oozing and vesiculation. There have also been accounts of rashes, edema, urticarial and other allergic symptoms as well as methemoglobinemia. Other adverse effects can include: tremors, twitching, dizziness, confusion, hypo-tension, vomiting, euphoria, and blurred or double …
Research
Cetacaine acts quickly in about 30 seconds and can last between 30–60 minutes. This is due to benzocaine causing the immediate anesthetic effect, while butamben and tetracaine hydrochloride causes the extended effect of Cetacaine.
The actual mechanism for the onset of anesthesia is unknown, but it is believed that the active ingredients reversibly block nerve conduction therefore causing the numbing sensation. This sta…