Precautions
What is desonide cream 0.05% used for?
Desonide topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions (eg, atopic dermatitis). This medicine is a corticosteroid (cortisone-like medicine or steroid). This medicine is available only with your doctor's prescription.
What is Desonate used to treat?
Desonide (Desonate) is a mild to moderate steroid medication that comes in many forms, and is used on the skin to relieve inflammation and itching caused by various skin conditions, including atopic dermatitis (eczema).
Can you use desonide cream 0.05 on your face?
To use desonide foam on your face, apply foam into your hands and gently rub the medicine into affected areas of face; do not apply desonide foam directly to your face. You should wash your hands after applying desonide foam.
Does Desonide help with dark spots?
Desonide reduces inflammation to lessen redness, swelling, itching, or any other discomfort you may be feeling. Desonide has been proven to be clinically useful in reducing post-inflammatory conditions such as melasma, hyperpigmentation, and sun, liver, and other dark spots.
How often can you apply desonide?
Adults—Apply to the affected area of the skin 2 or 3 times a day. Children—Use and dose must be determined by your doctor.
Can I buy desonide cream over the counter?
Desonide topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions (eg, atopic dermatitis). This medicine is a corticosteroid (cortisone-like medicine or steroid). This medicine is available only with your doctor's prescription.
How do you apply desonide cream to your face?
Apply a thin film of the medication to the affected area and gently rub in, usually 2-3 times daily, or as directed by your doctor. If using the gel, apply the gel usually only 2 times daily. Do not bandage, wrap, or cover the area unless you are instructed to do so by your doctor.
Is desonide good for a rash?
Desonide topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions (eg, atopic dermatitis). This medicine is a corticosteroid (cortisone-like medicine or steroid).
Is desonide an anti inflammatory?
Desonide is a synthetic nonfluorinated corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents.
Which ointment removes dark spots?
Best dark spot removal creamsBlue Nectar Natural Vitamin C Face Cream. ... Glowpink Dark Spot Corrector Cream. ... Re' Equil Skin Radiance Cream. ... Eeza Anti Blemish Face Cream. ... Dermafique Age Defying Nuit Regenerating Cream. ... DERMATOUCH Skin Radiance Cream. ... AURAVEDIC Dark Spot Removal Cream. ... Mamaearth Skin Correct Face Serum.More items...•
Does desonide thin skin?
High doses or long-term use of desonide topical can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.
Which ointment is best for dark spots?
Best Dark Spots Removal Creams For BodyFabindia Vitamin E Cream De-Pigmentation. ... Khadi Omorose Anti-Blemish Cream. ... VLCC Almond Honey: Deep Nourishing & Skin Brightening Body Lotion. ... Garnier Light Complete Moisturising Serum-In-Lotion. ... Nivea Whitening Even Tone Body Lotion.More items...•
Is desonide stronger than hydrocortisone?
Results: No differences in safety were observed between hydrocortisone and desonide.
Is desonide an anti inflammatory?
Desonide is a synthetic nonfluorinated corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents.
Can you use desonide on broken skin?
Large sores, broken skin, or severe skin injury at the application site—Use with caution. May increase risk for more side effects.
Which is stronger desonide or triamcinolone?
Clobetasol is a potent steroid, triamcinolone 0.1% is midstrength, and desonide is lower-potency. Clobetasol and triamcinolone 0.1% are generally utilized for skin disease on the body, whereas desonide is the appropriate choice for skin disorders on the face, groin, axillae, and breasts.
Before Taking This Medicine
You should not use Desonate if you are allergic to desonide.To make sure Desonate is safe for you, tell your doctor if you have: 1. any type of ski...
How Should I Use Desonate?
Desonate gel is usually applied 2 or 3 times daily. Follow all directions on your prescription label. Do not use this medicine in larger or smaller...
What Happens If I Miss A Dose?
Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not use extra medicine to make up t...
What Happens If I Overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.An overdose of...
What Should I Avoid While Using Desonate?
Avoid getting this medicine in your eyes. If contact does occur, rinse with water. Do not use Desonate gel on broken or infected skin. Also avoid u...
What Other Drugs Will Affect Desonate?
It is not likely that other drugs you take orally or inject will have an effect on topically applied Desonate. But many drugs can interact with eac...
What is desonate used for?
Desonate is indicated for the treatment of mild to moderate atopic dermatitis in patients 3 months of age and older. Patients should be instructed to use Desonate for the minimum amount of time as necessary to achieve the desired results because of the potential for Desonate to suppress the hypothalamic- pituitary -adrenal (HPA) ...
How long does desonate affect HPA?
The effect of Desonate on HPA axis function was investigated in pediatric subjects, with atopic dermatitis covering at least 35% of their body, who were treated with Desonate twice daily for 4 weeks. One of 37 subjects (3%) displayed adrenal suppression after 4 weeks of use, based on the cosyntropin stimulation test [see WARNINGS AND PRECAUTIONS ].
How much desonide is in a gram of desonate?
Each gram of Desonate contains 0.5 mg of desonide in an aqueous gel base of purified water, glycerin, propylene glycol, edetate disodium dihydrate, methylparaben, propylparaben, sodium hydroxide, and Carbopol® 981.
Why are pediatric patients at a greater risk than adults of HPA axis suppression when they are treated with topic?
Because of a higher ratio of skin surface area to body mass, pediatric patients are at a greater risk than adults of HPA axis suppression when they are treated with topical corticosteroids. They are therefore also at greater risk of glucocorticosteroid insufficiency after withdrawal of treatment and of Cushing's syndrome while on treatment.
What is ACTH test?
An ACTH stimulation test may be helpful in evaluating patients for HPA axis suppression. If HPA axis suppression is documented, an attempt should be made to gradually withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid. Manifestations of adrenal insufficiency may require supplemental systemic corticosteroids. Recovery of HPA axis function is generally prompt and complete upon discontinuation of topical corticosteroids.
How do corticosteroids get absorbed?
Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption. Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. They are metabolized primarily in the liver and then are excreted by the kidneys. Some corticosteroids and their metabolites are also excreted in the bile.
What are the adverse events of desonate?
The most common local adverse events in Desonate treated subjects were application site burning in 1% (4/425) and rash in 1% (3/425) followed by application site pruritus in < 1% (2/425).
Are you currently using Desonate Gel?
This survey is being conducted by the WebMD marketing sciences department.
What is desonide used for?
Uses. This medication is used to treat a variety of skin conditions (e. g., eczema, dermatitis, allergies, rash ). Desonide reduces the swelling, itching and redness that can occur in these types of conditions. Desonide is a mild corticosteroid.
How to apply a gel to a swollen ear?
Wash your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 2-3 times daily, or as directed by your doctor. If using the gel, apply the gel usually only 2 times daily. Do not bandage, wrap, or cover the area unless you are instructed ...
How to store a med?
Read the package labeling or ask your pharmacist for the storage requirements for the product you are using. Store the medication away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
How long does it take for a syringe to go away?
Tell your doctor if your condition persists or worsens after 2 weeks. Side Effects. Stinging, burning, itching, irritation, dryness, or redness may occur when first applied to the skin. This should disappear in a few days as your body adjusts to the medication.
Can desonide cause allergies?
Precautions. Before using desonide, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., hydrocortisone, prednisone ); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Can you take corticosteroid while pregnant?
Do not use if there is an infection or sore in the area to be treated. Children may be more sensitive to the effects of too much corticosteroid medication. Consult your doctor for more details. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
What Are the Side Effects of Desonate?
This is not a complete list of side effects and others may occur. A medical professional can advise you on side effects. If you experience other effects, contact your pharmacist or a medical professional. You may report side effects to the FDA at www.fda.gov/medwatch or 1-800-FDA-1088.
What Is Desonate Used For?
The Food and Drug Administration (FDA) has approved Desonate to treat mild to moderate atopic dermatitis (more commonly known as eczema) in people 3 months of age and older. 2
What Other Medications Interact With Desonate?
Desonate does not significantly interact with any medications, but you should avoid using other topical steroids since it can increase side effects. Let your healthcare provider know about all medications you take, including topical creams or ointments, so they can ensure your treatment regimen is safe and effective.
What Medications Are Similar?
Many topical steroids are available that come in other forms, including ointments, creams, lotions, solutions, foams, sprays, and gels. Deciding on a product will depend on the area of the body you are treating and the severity of your symptoms.
How Can I Stay Healthy While Taking Desonate?
Talk with your healthcare provider about all your symptoms and concerns. Together you will develop a plan to improve your discomfort and the appearance of your skin, so you can look and feel your best.
How long does it take for desonate to work?
Desonate should significantly improve your eczema symptoms within four weeks, although many people begin to see improvements sooner.
What is the FDA approved treatment for eczema?
The Food and Drug Administration (FDA) has approved Desonate to treat mild to moderate atopic dermatitis (more commonly known as eczema) in people 3 months of age and older. 2
What factors predispose a patient using a topical corticosteroid to HPA?
Factors that predispose a patient using a topical corticosteroid to HPA axis suppression include the use of more potent steroids, use over large surface areas, use over prolonged periods, use under occlusion, use on an altered skin barrier, and use in patients with liver failure.
What is desonate used for?
Desonate is indicated for the treatment of mild to moderate atopic dermatitis in patients 3 months of age and older. Patients should be instructed to use Desonate for the minimum amount of time as necessary to achieve the desired results because of the potential for Desonate to suppress the hypothalamic-pituitary-adrenal (HPA) ...
Why are pediatric patients at a greater risk than adults of HPA axis suppression when they are treated with topic?
Because of a higher ratio of skin surface area to body mass, pediatric patients are at a greater risk than adults of HPA axis suppression when they are treated with topical corticosteroids. They are therefore also at greater risk of glucocorticosteroid insufficiency after withdrawal of treatment and of Cushing's syndrome while on treatment.
What is ACTH test?
An ACTH stimulation test may be helpful in evaluating patients for HPA axis suppression. If HPA axis suppression is documented, an attempt should be made to gradually withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid. Manifestations of adrenal insufficiency may require supplemental systemic corticosteroids. Recovery of HPA axis function is generally prompt and complete upon discontinuation of topical corticosteroids.
How do corticosteroids get absorbed?
Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption. Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. They are metabolized primarily in the liver and then are excreted by the kidneys. Some corticosteroids and their metabolites are also excreted in the bile.
What are the adverse events of desonate?
The most common local adverse events in Desonate treated subjects were application site burning in 1% (4/425) and rash in 1% (3/425) followed by application site pruritus in <1% (2/425).
What is the mechanism of action of desonide?
The mechanism of action of desonide is unknown.
What is desonide used for?
This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash). Desonide reduces the swelling, itching and redness that can occur in these types of conditions. Desonide is a mild corticosteroid. Use this medication only on the skin. Wash your hands.
How to store a med?
Different brands/strengths of this medication may have different storage requirements. Read the package labeling or ask your pharmacist for the storage requirements for the product you are using. Store the medication away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
How to use desonide?
Desonide is a mild corticosteroid. How to use. Use this medication only on the skin. Wash your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 2-3 times daily, or as directed by your doctor. If using the gel, apply ...
Why is corticosteroid not used?
diabetes. immune system problems. other skin conditions (e.g., rosacea, perioral dermatitis) Do not use if there is an infection or sore in the area to be treated . Children may be more sensitive to the effects of too much corticosteroid medication.
What medications suppress the immune system?
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: oral corticosteroids (e.g., prednisone) other topical corticosteroids (e.g., hydrocortisone) drugs that suppress the immune system (e.g., cyclosporine)
How long does it take for a syringe to go away?
Tell your doctor if your condition persists or worsens after 2 weeks. Side effects. Stinging, burning, itching, irritation, dryness, or redness may occur when first applied to the skin. This should disappear in a few days as your body adjusts to the medication.
Can desonide cause allergies?
Before using desonide, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., hydrocortisone, prednisone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
What is a desonate?
DESONATE is a corticosteroid indicated for the topical treatment of mild to moderate atopic dermatitis in patients 3 months of age and older. (1) ( 1)
What are the adverse events of desonate?
The most common local adverse events in DESONATE treated subjects were application site burning in 1% (4/425) and rash in 1% (3/425) followed by application site pruritus in <1% (2/425).
What is ACTH test?
An ACTH stimulation test may be helpful in evaluating patients for HPA axis suppression. If HPA axis suppression is documented, an attempt should be made to gradually withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid. Manifestations of adrenal insufficiency may require supplemental systemic corticosteroids. Recovery of HPA axis function is generally prompt and complete upon discontinuation of topical corticosteroids.
Why are pediatric patients at a greater risk than adults of HPA axis suppression when they are treated with topic?
Because of a higher ratio of skin surface area to body mass, pediatric patients are at a greater risk than adults of HPA axis suppression when they are treated with topical corticosteroids. They are therefore also at greater risk of glucocorticosteroid insufficiency after withdrawal of treatment and of Cushing's syndrome while on treatment.
Can you discontinue desonate?
If irritation develops, DESONATE should be discontinued and appropriate therapy instituted. Allergic contact dermatitis with corticosteroids is usually diagnosed by observing failure to heal rather than noting a clinical exacerbation as with most topical products not containing corticosteroids. Such an observation should be corroborated with appropriate diagnostic patch testing.
Can topical corticosteroids be used for HPA?
Because of the potential for systemic absorption, use of topical corticosteroids may require that patients be periodically evaluated for HPA axis suppression. Factors that predispose a patient using a topical corticosteroid to HPA axis suppression include the use of more potent steroids, use over large surface areas, use over prolonged periods, use under occlusion, use on an altered skin barrier, and use in patients with liver failure.
Is desonate toxic to children?
Pediatric patients may be more susceptible than adults to systemic toxicity from equivalent doses of DESONATE due to their larger skin surface-to-body mass ratios [see Use In Specific Populations ( 8.4 )].
Indications and Usage For Desonate
This medication is used to treat a variety of skin conditions (such as eczema, dermatitis, allergies, rash).
May Treat: Allergic dermatitis · Atopic dermatitis · Contact dermatitis · Cutaneous T-cell lymphoma · Discoid lupus erythematosus and more
Alternate Brand Names: Tridesilon
Drug Class: Dermatological - Glucocorticoid
Availability: Prescription Required
Pregnancy: Consult a doctor before using
May Treat: Allergic dermatitis · Atopic dermatitis · Contact dermatitis · Cutaneous T-cell lymphoma · Discoid lupus erythematosus and more
Alternate Brand Names: Tridesilon
Drug Class: Dermatological - Glucocorticoid
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
Manufacturer: BAYER, PHARM DIV · LEO PHARMA INC.
- Keep away from eyes
- Wash hands before and after using
- Clean and dry skin, then use a thin layer on area.
- Keep away from eyes
- Wash hands before and after using
- Clean and dry skin, then use a thin layer on area.
- Do not bandage unless told by doctor.
- Avoid plastic pants on children
- Call doctor if condition does not improve.
- For cream products : Use only prescribed dura- tion. Ask MD if unsure. Use for other problems only if directed by MD.
- For foam products : If available, read the patient package insert. Keep medicine away from heat or flames.
Desonate Dosage and Administration
Contraindications
Warnings and Precautions
Adverse Reactions
Use in Specific Populations
- Apply a thin layer to the affected areas two times daily and rub in gently. Discontinue use when control is achieved. If no improvement is seen within 4 weeks, reassessment of diagnosis may be necessary. Treatment beyond 4 consecutive weeks is not recommended. Do not use with occlusive dressings. Avoid contact with eyes or other mucous membranes. For topical use only. …
Overdosage
- Desonate is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
Desonate Description
- Effects on Endocrine System
Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for clinical glucocorticosteroid insufficiency. This may occur during treatment or upon withdrawal of the topical corticosteroid. The effect of … - Local Adverse Reactions with Topical Corticosteroids
Local adverse reactions may be more likely to occur with occlusive use, prolonged use or use of higher potency corticosteroids. Reactions may include skin atrophy, striae, telangiectasias, burning, itching, irritation, dryness, folliculitis, acneiform eruptions, hypopigmentation, perioral d…
Desonate - Clinical Pharmacology
- Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. In controlled clinical studies of 425 Desonate-treated subjects and 157 Vehicle-treated subjects, adverse events occurred at th…
Nonclinical Toxicology
- Pregnancy
There are no adequate and well-controlled studies in pregnant women. Therefore, Desonate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Corticosteroids have been shown to be teratogenic in laboratory animals when administer… - Nursing Mothers
Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects. It is not known whether topical administration of corticosteroids could result in sufficient systemic abso…