
Precautions
DIPROLENE AF Cream is a prescription corticosteroid medicine used on the skin (topical) for the relief of redness, swelling, heat, pain (inflammation) and itching, caused by certain skin problems in people 13 years of age and older. DIPROLENE AF Cream should not be used in children under 13 years of age.
What is Diprolene AF cream used for?
Diprolene AF Description. Diprolene AF (augmented betamethasone dipropionate) Cream 0.05% contains betamethasone dipropionate USP, a synthetic adrenocorticosteroid, for topical use in a cream base. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a slight degree of mineralocorticoid activity.
Is Diprolene AF a steroid?
Betamethasone is a highly potent steroid that prevents the release of substances in the body that cause inflammation. Diprolene (for the skin) is used to treat the inflammation and itching caused by a number of skin conditions such as eczema or psoriasis. Diprolene may also be used for purposes not listed in this medication guide.
What is betamethasone and Diprolene used for?
The most common side effects of Diprolene AF Cream in children include thinning of the skin (atrophy), tiny red lines or blood vessels showing under the skin (telangiectasia), bruising and shininess. These are not all of the possible side effects of Diprolene AF Cream.
What are the side effects of Diprolene AF cream in children?

What does the AF mean in Diprolene AF?
by Drugs.com Diprolene AF is a cream that has been discontinued in the US, but generic forms of this “augmented” betamethasone dipropionate cream 0.05% are available. AF stands for “augmented formulation”.
How do you use Diprolene?
Use DIPROLENE Ointment exactly as your healthcare provider tells you to use it. Apply a thin layer (film) of DIPROLENE Ointment to the affected skin area 1 or 2 times each day. Do not use more than 50 grams of DIPROLENE Ointment in 1 week.
What are the side effects to Diprolene?
Side effects of Diprolene include:application site reactions (burning, itching, irritation, redness, peeling, and dry skin),thinning of your skin,blistering skin, or.stretch marks.
How long does it take for Diprolene to work?
6. Response and effectiveness. It takes about one to three days for Diprolene to start working when it is being used to treat eczema. Some improvement in symptoms such as inflammation (redness) and itching, should be noticed within this time.
Where should you not apply betamethasone?
Avoid use in the genital and rectal areas and in skin creases and armpits unless directed by your doctor. If you are using betamethasone on a child's diaper area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.
Can you use betamethasone on your private parts?
This medicine is for use on the skin only. Do not get it in your eyes, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns.
Is Diprolene a steroid?
DIPROLENE AF Cream is a high-potency corticosteroid. Treatment with DIPROLENE AF Cream should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis [see WARNINGS AND PRECAUTIONS].
Is betamethasone a strong steroid?
Betamethasone is a highly potent steroid that prevents the release of substances in the body that cause inflammation. Betamethasone topical (for the skin) is used to treat the inflammation and itching caused by a number of skin conditions such as eczema or psoriasis.
What skin conditions does betamethasone treat?
Betamethasone skin treatments are used to treat itching, swollen and irritated skin. They can help with conditions such as eczema, contact dermatitis and psoriasis. Betamethasone skin treatments are available on prescription only.
How long does betamethasone stay in your body?
Betamethasone belongs to the glucocorticoid class of medication. It is a stereoisomer of dexamethasone, the two compounds differing only in the spatial configuration of the methyl group at position 16 (see steroid nomenclature)....Betamethasone.Clinical dataElimination half-life36-54 hoursExcretionKidney (in urine)Identifiers32 more rows
Is betamethasone stronger than hydrocortisone?
Some types of betamethasone are up to 600 times as potent as hydrocortisone. Both medications are available in various forms, including: Ointments.
Do you need a prescription for diprolene?
Official answer. No, Diprolene is not available as an over-the-counter (OTC) product. Diprolene (augmented betamethasone dipropionate) is a super-high potency topical corticosteroid (“steroid”) medication used on the skin and it requires a prescription from your healthcare provider.
How long can I use Diprosone cream?
Do not use DIPROSONE for more than four weeks at a time unless your doctor tells you.
Can I use Diprolene on my face?
Use this medication on the skin only. However, do not use it on the face, groin, or underarms or for diaper rash unless directed to do so by your doctor. Wash and dry your hands. Before applying the medication, clean and dry the affected area.
Is Diprolene a steroid?
DIPROLENE AF Cream is a high-potency corticosteroid. Treatment with DIPROLENE AF Cream should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis [see WARNINGS AND PRECAUTIONS].
How long can you use taclonex?
Do not use this medication for more than 4 weeks if you are using the ointment or foam (or 8 weeks if you are using the cream) unless directed by your doctor.
Can Diprolene cream be used for poison ivy?
Yes, Diprolene cream can be used to treat poison ivy, if prescribed by your doctor specifically for this use. The brand name product Diprolene (bet...
Diprolene: AF vs Augmented vs Regular - What does this mean?
Topical skin preparations, such as Diprolene, which are described as AF, Augmented, or regular, have differences in the way they are formulated tha...
Is Diprolene available over-the-counter (OTC)?
No, Diprolene is not available over-the-counter. Diprolene (augmented betamethasone dipropionate) is a super-high potency topical corticosteroid (“...
What is the mechanism of action of diprolenes?
Corticosteroids play a role in cellular signaling, immune function, inflammation, and protein regulation; however, the precise mechanism of action of DIPROLENE AF Cream in corticosteroid responsive dermatoses is unknown.
Why does diprolene cream stop working?
Too much DIPROLENE AF Cream passing through your skin can cause your adrenal glands to stop working properly . Your healthcare provider may do blood tests to check for adrenal gland problems. Cushing's syndrome, a condition that happens when your body is exposed to too much of the hormone cortisol.
How old do you have to be to use diproleone cream?
DIPROLENE AF Cream should not be used in children under 13 years of age.
Is betamethasone dipropionate excreted in breast milk?
There are no data regarding the excretion of betamethasone dipropionate in breast milk, the effects on the breastfed infant, or the effects on milk production after topical application of DIPROLENE AF Cream to women who are breastfeeding.
Does diprolene cream cause telangiectasia?
The most common side effects of DIPROLENE AF Cream in children include thinning of the skin ( atrophy ), tiny red lines or blood vessels showing under the skin (telangiectasia), bruising and shininess.
Can diprolene AF cream be used on the skin?
DIPROLENE AF Cream can pass through your skin. Too much DIPROLENE AF Cream passing through your skin can cause your adrenal glands to stop working properly. Your healthcare provider may do blood tests to check for adrenal gland problems.
Does diproleone AF cream cause stinging?
The most common side effect of DIPROLENE AF Cream in adults includes stinging. The most common side effects of DIPROLENE AF Cream in children include thinning of the skin (atrophy), tiny red lines or blood vessels showing under the skin (telangiectasia), bruising and shininess.
What is a diprolene AF cream?
Diprolene AF (augmented betamethasone dipropionate) Cream 0.05% contains betamethasone dipropionate USP, a synthetic adrenocorticosteroid, for topical use in a cream base. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a slight degree of mineralocorticoid activity. Betamethasone dipropionate is the 17,21-dipropionate ester of betamethasone.
Is diprolene AF cream contraindicated?
Diprolene AF Cream is contraindicated in patients who are hypersensitive to betamethasone dipropionate, to other corticosteroids, or to any ingredient in this preparation.
Is betamethasone dipropionate soluble in water?
Betamethasone dipropionate is a white to creamy white, odorless crystalline powder, insoluble in water.
Can diprolene be used for breast feeding?
It is possible that topical administration of large amounts of betamethasone dipropionate could result in sufficient systemic absorption to produce detectable quantities in human milk. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for Diprolene AF Cream and any potential adverse effects on the breastfed infant from Diprolene AF Cream or from the underlying maternal condition.
Is betamethasone dipropionate excreted in breast milk?
There are no data regarding the excretion of betamethasone dipropionate in breast milk, the effects on the breastfed infant, or the effects on milk production after topical application of Diprolene AF Cream to women who are breastfeeding.
Does Diprolene AF cream cause cataracts?
Use of topical corticosteroids, including Diprolene AF Cream, may increase the risk of posterior subcapsular cataracts and glaucoma. Cataracts and glaucoma have been reported postmarketing with the use of topical corticosteroid products, including Diprolene AF Cream [see Adverse Reactions (6.2) ].
What is betamethasone used for?
Uses. This medication is used to treat a variety of skin conditions (e.g., eczema, dermatitis, allergies, rash ). Betamethasone reduces the swelling, itching, and redness that can occur in these types of conditions. This medication is a strong to very strong (high- to super-high-potency) corticosteroid. The strength depends on the form (cream, gel, ...
Can you use a saline pill on your face?
Use this medication on the skin only. However, do not use it on the face, groin, or underarms or for diaper rash unless directed to do so by your doctor.
Are you currently using Diprolene AF 0.05 % Topical Cream?
This survey is being conducted by the WebMD marketing sciences department.
What is diprolene cream?
Diprolene AF (augmented betamethasone dipropionate) Cream 0.05% is a high-potency corticosteroid used to relieve inflammation and itchiness due to a skin disease caused by a reaction to other corticosteroids. Diprolene AF is available in generic form.
What are the side effects of diprolene?
Common side effects of Diprolene AF include: 1 skin redness, 2 burning, 3 itching, 4 peeling, 5 irritation, and 6 dryness at the application area
How many people have had adverse reactions to diproleone AF cream?
In a controlled clinical trial involving 67 pediatric subjects from 3 months to 12 years of age, the adverse reactions associated with the use of DIPROLENE AF Cream occurred in 7 of 67 (10%) subjects. Reported reactions included signs of skin atrophy (telangiectasia, bruising, shininess).
Can you take cyclosporine with diprolene?
Prednisone and cyclosporine may interact with Diprolene AF. Tell your doctor all medications you take. Do not use Diprolene AF if you have an infection or sore on the affected area. Before using Diprolene AF tell your doctor if you have poor blood circulation, immune system problems, rosacea, or perioral dermatitis.
Can you use diprolene AF while pregnant?
If you are pregnant only use Diprolene AF if clearly needed. Talk to your doctor if you are breastfeeding before using Diprolene AF.
Does diprolene cause stretch marks?
Other side effects of Diprolene AF include thinning of your skin, blistering skin, or stretch marks.
What are some things I need to know or do while I take Diprolene?
Tell all of your health care providers that you take Diprolene. This includes your doctors, nurses, pharmacists, and dentists.
How is Diprolene best taken?
Use Diprolene as ordered by your doctor. Read all information given to you. Follow all instructions closely.
What are the side effects of Diprolene that I need to call my doctor about immediately?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
What is a saline solution used for?
It is used to treat skin irritation.
Can you take diprolene with all your medications?
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Diprolene with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
Can you give a child diprolene?
Different brands of Diprolene may be for use in different ages of children. Talk with the doctor before giving Diprolene to a child.
Who to talk to about diprolene?
Check with your pharmacist. If you have any questions about Diprolene, please talk with your doctor, nurse, pharmacist, or other health care provider.
Read drug prescription
It is very important to know about what medicine is given by the doctor, for what condition, and when it needs to be taken in what dose. This information given by the doctor is called Prescription. The patients should be familiar with the medicine prescription, and the details about the medicine before purchasing it and using it.
Compare prices at online shops
Prices of the drug can vary in different shops. There will be a variation in price from pharmacy to an online shop. Most online shops will have a little lower price when compared to pharmacy stores, so you need to cross check before buying. Just go to a nearest pharmacy store and check for prices before you decide on buying.
Select the most affordable brand or generic drug
Generic drug is the basic drug with an active substance in it, and the name of the generic drug is same as active substance most of the times. Like Acetaminophen/Paracetemol is Generic name and it has different brand names like Tylenol, Acimol, Crocin, Calpol etc.
DIPROLENE AF - Frequently asked Questions
In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine.
Reviews
Following the study conducted by gmedication.com on Diprolene AF, the result is highlighted below. However, it must be clearly stated that the survey and result is based solely on the perception and impression of visitors and users of the website as well as consumers of Diprolene AF.

Indications and Usage For Diprolene Af
This medication is used to treat a variety of skin conditions (such as eczema, dermatitis, allergies, rash).
Status: Discontinued
May Treat: Allergic dermatitis · Atopic dermatitis · Contact dermatitis · Cutaneous T-cell lymphoma · Discoid lupus erythematosus and more
Alternate Brand Names: Diprolene
Drug Class: Dermatological - Glucocorticoid
Availability: Prescription Required
Status: Discontinued
May Treat: Allergic dermatitis · Atopic dermatitis · Contact dermatitis · Cutaneous T-cell lymphoma · Discoid lupus erythematosus and more
Alternate Brand Names: Diprolene
Drug Class: Dermatological - Glucocorticoid
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
Manufacturer: MERCK SHARP & D
Diprolene Af Dosage and Administration
Dosage Forms and Strengths
Contraindications
Warnings and Precautions
Adverse Reactions
- Apply a thin film of Diprolene AF Cream to the affected skin areas once or twice daily. Therapy should be discontinued when control is achieved. Diprolene AF Cream is a high-potency corticosteroid. Treatment with Diprolene AF Cream should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis [see Warnin…
Use in Specific Populations
- Cream, 0.05%. Each gram of Diprolene AF Cream, 0.05% contains 0.643 mg betamethasone dipropionate (equivalent to 0.5 mg betamethasone) in a white cream base.
Diprolene Af Description
- Diprolene AF Cream is contraindicated in patients who are hypersensitive to betamethasone dipropionate, to other corticosteroids, or to any ingredient in this preparation.
Diprolene Af - Clinical Pharmacology
- Effects on Endocrine System
Diprolene AF Cream can produce reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency. This may occur during treatment or after withdrawal of treatment. Factors that predispose to HPA axis suppression inc… - Ophthalmic Adverse Reactions
Use of topical corticosteroids, including Diprolene AF Cream, may increase the risk of posterior subcapsular cataracts and glaucoma. Cataracts and glaucoma have been reported postmarketing with the use of topical corticosteroid products, including Diprolene AF Cream [see Adverse Reac…
Nonclinical Toxicology
- Clinical Trials Experience
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice. In controlled clinical trial… - Postmarketing Experience
Because adverse reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Postmarketing reports for local adverse reactions to topical corticosteroids may also …