Precautions
Dec 02, 2020 · Evamist is a transdermal spray containing estradiol. Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body. Each spray delivers 90 mcL which contains 1.53 mg of estradiol. Evamist is used to reduce moderate to severe hot flashes due to menopause.
What is Evamist?
Jan 10, 2022 · What is Evamist and how is it used? Evamist is a prescription medicine used to treat the symptoms of Vulvar and Vaginal Atrophy in Menopause, Hypoestrogenism from Castration, Hypogonadonism, or Ovarian Failure, Metastatic Breast Cancer, Hypoestrogenism, Osteoporosis, Vasomotor symptoms associated with Menopause, and Prostate Cancer. …
What is Evamist (estradiol) used for?
Evamist (estradiol) is an easy-to-use topical spray that helps relieve the hot flashes and night sweats caused by menopause. It absorbs well into your skin without needing to rub it in and is a good option if you don’t want to or can't use estrogen pills or patches.
Can you use Evamist on your face?
What is evamist used for? Evamist (estradiol transdermal) Spray is a form of estrogen, a female sex hormone, used to treat certain symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. Click to see full answer. Similarly, it is asked, where can I …
Why should I avoid Evamist?
Evamist ® offers the most titration choices for a single HRT prescription. An applicator that provides the flexibility of 3 daily dosing options. Enables women to start with the lowest dose and titrate according to their healthcare provider’s direction. Use of estrogen alone, or in combination with a progestin, should be with the lowest ...
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Find everything you need to know about Evamist, including what it is used for, warnings, reviews, side effects, and interactions. Learn more about Evamist at EverydayHealth.com.
Does Evamist help with vaginal dryness?
How long does Evamist last?
Is Evamist a HRT?
Is Evamist still available?
Does Evamist cause weight gain?
Where can I apply Evamist?
Does estradiol cause weight gain?
When should you take estrogen pills?
How is divigel prescribed?
Is there a generic Evamist?
How is Evamist supplied?
Is vagifem an estrogen?
The estrogen used in Vagifem® 10 mcg is called “estradiol,” which is the same estrogen that your body makes.
Before Using This Medicine
You should not use Evamist if you have: 1. abnormal vaginal bleeding that has not been checked by a doctor; 2. any type of breast, uterine, or horm...
How Should I Use Evamist?
Use Evamist exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller a...
What Happens If I Miss A Dose?
Use the missed dose as soon as you remember. If you are more than 12 hours late, skip the missed dose. Do not use extra medicine to make up the mis...
What Happens If I Overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, stomach pain, brea...
What Should I Avoid While Using Evamist?
Do not apply sunscreen to your skin at the same time you apply Evamist.Avoid getting Evamist in your eyes. If this does happen, rinse with water.Gr...
What Other Drugs Will Affect Evamist?
Other drugs may interact with estradiol topical, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of...
Does Evamist (estradiol) cause weight gain?
Weight gain is not a common side effect of Evamist (estradiol). If you notice unusual weight gain after starting this medication, contact your prov...
Can I shower after applying Evamist (estradiol)?
In order for Evamist (estradiol) to be completely absorbed by your body, wait at least 1 hour after applying your dose before you get the area wet.
Can I apply sunscreen after using Evamist (estradiol)?
It's better to apply sunscreen an hour before you use Evamist (estradiol) if possible. Applying sunscreen after you use this medication can prevent...
What are the most common side effects of Evamist (estradiol)?
The most common side effects of Evamist (estradiol) include headache, breast tenderness, and nipple pain.
Is it normal to experience spotting or vaginal bleeding after starting Evamist (estradiol)?
No. Vaginal bleeding after you have entered menopause is not typical, even if you are using estrogen products like Evamist (estradiol) to relieve s...
What is an evamist?
Evamist (estradiol transdermal spray) is designed to deliver estradiol to the blood circulation following topical application to the skin of a rapidly drying solution from a metered-dose pump.
How to report evamist side effects?
Tell your healthcare provider if you have any side effect that bothers you or does not go away. You may report side effects to Perrigo at 1-866-634-9120 or to FDA at 1-800-FDA-1088.
Does Evamist help with endometrial cancer?
Evamist Dosage and Administration. Generally, when estrogen is prescribed for a postmenopausal woman with a uterus, a progestin should also be considered to reduce the risk of endometrial cancer. A woman without a uterus does not need a progestin.
What is an evamist?
Evamist (estradiol transdermal spray) is designed to deliver estradiol to the blood circulation following topical application to the skin of a rapidly drying solution from a metered-dose pump.
How much estradiol is in evamist?
One spray of Evamist contains 1.53 mg estradiol. The metered-dose pump should be held upright and vertical for spraying. Before a new applicator is used for the first time, the pump should be primed by spraying 3 times into the cover.
What temperature should evamist be stored at?
Store EVAMIST at room temperature 68°F to 77°F (20°C to 25°C )
Why was the WHI study stopped?
The WHI estrogen-alone substudy was stopped early because an increased risk of stroke was observed , and it was deemed that no further information would be obtained regarding the risks and benefits of estrogen-alone in predetermined primary endpoints. Results of the estrogen-alone substudy, which included 10,739 women (average 63 years of age, range 50 to 79 years of age; 75.3 percent White, 15.1 percent Black, 6.1 percent Hispanic, 3.6 percent Other), after an average follow-up of 7.1 years are presented in Table 5.
How long does it take for evamist to absorb?
In order for Evamist (estradiol) to be completely absorbed by your body, wait at least 1 hour after applying your dose before you get the area wet.
How long before you use evamist should you apply sunscreen?
It's better to apply sunscreen an hour before you use Evamist (estradiol) if possible. Applying sunscreen after you use this medication can prevent your body from absorbing the medication properly. If you need to apply sunscreen after Evamist (estradiol), make sure it's been at least an hour since applying your dose.
Can evamist cause headaches?
Let your provider know if you experience vaginal bleeding, lumps in your breast, changes to your vision, or severe headaches after starting Evamist (estradiol). These are not typical side effects and could be a sign of more serious problems.
Does Evamist cause weight gain?
Weight gain is not a common side effect of Evamist (estradiol). If you notice unusual weight gain after starting this medication, contact your provider.
Can you take evamist while pregnant?
Because of this, if you have or have had any problems with your liver, including liver problems during a past pregnancy, you should not use Evamist (estradiol).
Can you use evamist on your forearm?
If more than 1 spray is needed, always use a different area on your forearm. Don't spray Evamist (estradiol) on any areas where the skin is broken (cuts, scrapes, wounds).
What is evamist spray?
Evamist ® (estradiol transdermal spray) is an estrogen indicated for the treatment of moderate-to-severe vasomotor symptoms due to menopause.
What is an applicator for estrogen?
An applicator that provides the flexibility of 3 daily dosing options. Use of estrogen alone, or in combination with a progestin, should be with the lowest effective dose and the shortest duration consistent with treatment goals and risks for the individual woman.
Uses
Treatment of moderate to severe vasomotor symptoms associated with the menopause.
Side Effects
GI disturbances, genitourinary changes, haematologic disorders, CV and CNS effects, endocrine and metabolic disorders, cholestatic jaundice, local skin reactions, chorea, contact lens intolerance, steeping of corneal curvature, pulmonary thromboembolism, carbohydrate intolerance.
Precaution
Conditions exacerbated by fluid retention; hypercalcaemia, cerebrovascular diorders, coronary artery disease, gall bladder diseases; lipid effects; familial defects of lipoprotein metabolism. May increase BP, risk of venous thromboembolism, breast cancer, benign hepatic adenoma, endometrial cancer and size of preexisting uterine leiomyomata.
Interaction
CYP1A2 and CYP3A4 inducers e.g. aminoglutethimide, carbamazepine, phenobarbital, and rifampin may decrease the effects of estradiol. May enhance the effects of hydrocortisone and prednisolone when used together.
Volume of Distribution
Estrogens administered exogenously distribute in a similar fashion to endogenous estrogens. They can be found throughout the body, especially in the sex hormone target organs, such as the breast, ovaries and uterus.
Half Life
The terminal half-lives for various estrogen products post oral or intravenous administration has been reported to range from 1-12 hours. One pharmacokinetic study of oral estradiol valerate administration in postmenopausal women revealed a terminal elimination half-life of 16.9 ± 6.0 h.
Clearance
In one pharmacokinetic study, the clearance of orally administered micronized estradiol in postmenopausal women was 29.9±15.5 mL/min/kg. Another study revealed a clearance of intravenously administered estradiol was 1.3 mL/min/kg.
What to do if side effects persist?
If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Is Evamist spray an aerosol?
Evamist Spray, Non-Aerosol. Warnings: Estrogens, either used alone or with another hormone ( progestin ), have rarely caused very serious side effects. Discuss the risks and benefits of hormone treatment with your doctor. Estrogens should not be used to prevent heart disease or dementia. Estrogens can increase the risk of cancer ...
Evamist Dosage and Administration
This medication is a female hormone (estrogen). It is absorbed through the skin and enters into the bloodstream. It is used by women to help reduce a certain symptom of menopause (hot flashes). Symptoms of menopause are caused by the body making less estrogen. If you are using estrogens to treat only vaginal symptoms of menopause (such as vaginal dryness/burning/itching), products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected.
May Treat: Advanced prostatic carcinoma · Atrophic vaginitis associated with menopause · Atrophy of vulva · Dyspareunia due to menopausal vulvovaginal atrophy · Female hypogonadism and more
Drug Class: Estrogens · Menopausal Symptoms Supressant - Hormonal Agents · Vaginal Estrogens
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
May Treat: Advanced prostatic carcinoma · Atrophic vaginitis associated with menopause · Atrophy of vulva · Dyspareunia due to menopausal vulvovaginal atrophy · Female hypogonadism and more
Drug Class: Estrogens · Menopausal Symptoms Supressant - Hormonal Agents · Vaginal Estrogens
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
- If available, read the patient package insert
- See doctor regularly for examinations.
- Not recommended during pregnancy.
- If available, read the patient package insert
- See doctor regularly for examinations.
- Not recommended during pregnancy.
- Tell doctor your complete medical history
- Not smoking lowers risk for heart attack/stroke.
- Use sunscreen
- Use sunscreen
- For cream with applicator products : Learn how to correctly use this medicine. Keep all medical appointments.
- For gel in packet products : Apply to clean/dry/intact skin as directed. Do not allow others to touch application site.
- For patch, transdermal semiweekly products : May make you dizzy. Use caution when driving. Ask MD about lifestyle changes for your symptoms. Skin may be more prone to sunburn.
- For patch, transdermal weekly products : Apply to clean/dry skin on buttocks or abdomen. Apply to clean/dry/intact skin on the abdomen.
- For ring, vaginal products : Call MD now for dizziness fever & sunburn-like rash.
- For tablet products : Tell Dr/dentist on drug prior to any surgery. Avoid sun lamps/prolonged direct sun.
Dosage Forms and Strengths
Contraindications
Warnings and Precautions
Adverse Reactions
Use in Specific Populations
Overdosage
Evamist Description
Evamist - Clinical Pharmacology
Nonclinical Toxicology