Common tests & procedures
Immune thrombocytopenia (ITP) is not cancer, although some confuse it with blood cancer (leukemia). Learn about symptoms, causes, and treatment. Read more: Is ITP Considered Cancer? Article Some blood disorders are forms of cancer. Others are benign.
Is ITP considered cancer?
What Even Causes ITP?
- ITP happens when your immune system accidentally targets platelets. As you might already know, your immune system is your body’s basic line of defense against disease. ...
- A bacterial or viral infection can trigger ITP. ...
- Other autoimmune disorders can be a factor as well. ...
- And FYI: Pregnancy can exacerbate symptoms. ...
- Treating ITP depends on the cause.
What causes ITP blood disorder?
When being evaluated by a medical professional for ITP, exams may include: 2
- A skin check, looking for any evidence of bleeding, such as bruises or petechiae
- Inspection of the mouth and gums, looking for bleeding or blood blisters
- Examination of the abdomen to feel for the size of the spleen, as sometimes the spleen is enlarged in ITP
How is ITP diagnosed?
Immune thrombocytopenia (ITP)
- Overview. Immune thrombocytopenia (ITP) is a disorder that can lead to easy or excessive bruising and bleeding.
- Symptoms. Immune thrombocytopenia may have no signs and symptoms. ...
- Causes. ...
- Risk factors. ...
- Complications. ...
What is ITP diagnosis?
Is ITP a serious disease?
For most people with ITP, the condition isn't serious or life-threatening. For example, acute ITP in children often resolves within 6 months or less without treatment. Chronic ITP, though, can last for many years. Still, people can live for many decades with the disease, even those with severe cases.
What is the main cause of ITP?
Immune thrombocytopenia usually happens when your immune system mistakenly attacks and destroys platelets, which are cell fragments that help blood clot. In adults, this may be triggered by infection with HIV , hepatitis or H. pylori — the type of bacteria that causes stomach ulcers.
What is the best treatment for ITP?
Since spontaneous remissions are uncommon in adults with ITP, the administration of glucocorticoids is the recommended treatment when necessary. Prednisone (1 mg/kg per day orally) or high-dose dexamethasone (HDD), 40 mg/day orally for 4 days, repeated every 14–28 days as needed, are the regimens most commonly used.
What is ITP illness?
Idiopathic thrombocytopenic purpura is a blood disorder characterized by an abnormal decrease in the number of platelets in the blood. Platelets are cells in the blood that help stop bleeding. A decrease in platelets can result in easy bruising, bleeding gums and internal bleeding.
Can ITP be cured?
A: While there is no cure for ITP, many patients find their platelet count improves following treatment. What proves difficult for many ITP patients is finding the treatment that works for them without unwanted side effects. Some patients report that changing their diet or lifestyle helps them feel better.
Is ITP painful?
The symptoms usually begin suddenly and may include headache, fever, loss of appetite, cramping abdominal pain and/or joint pain. The resemblance to ITP is that red or purple spots typically appear on the skin that may resemble bruises, but thrombocytopenia is quite uncommon.
Is ITP a blood disease?
Immune thrombocytopenic purpura (ITP) is a blood disorder characterized by a decrease in the number of platelets in the blood. Platelets are cells in the blood that help stop bleeding.
What does ITP look like?
One of the most common symptoms of ITP is a skin condition called petechiae. These are small red bumps on your skin caused by bleeding from underneath. Petechiae can look like a red rash at first, but the bumps are slightly raised, scattered, and the size of pinpoints. They can also have a purplish tinge.
How can I increase my platelets fast?
How to Increase Platelet Count:Milk. We all know that milk is a rich source of calcium and protein and is important in maintaining the strength of bones and muscles in our body. ... Green Leafy Vegetables: ... Papaya Leaf Extract: ... Pomegranate: ... Pumpkin: ... Wheatgrass: ... Vitamin B-12. ... Iron.More items...
Can ITP be caused by stress?
Research suggests that physical or psychological stress and the resultant oxidative stress in the body may also trigger episodes of ITP,7 exacerbate fatigue15 and prolong duration of the platelet disorder in children.
What foods should you avoid with ITP?
Eat Less...Canned and frozen foods and leftovers. The nutritional value of food deteriorates with time.White flour, white rice and processed foods. ... Hydrogenated, partially hydrogenated or trans-fats. ... Sugar. ... Dairy products. ... Meat. ... Alcoholic beverages. ... Foods that can interfere with blood clotting.More items...
Is ITP a form of leukemia?
Immune thrombocytopenia (ITP) is not cancer, although some confuse it with blood cancer (leukemia). If you have a low platelet count (thrombocytopenia), your doctor will first rule out conditions, such as ITP, before thinking of blood cancer. Cancer treatments can also result in ITP.
Can ITP lead to other diseases?
Conclusion. In conclusion, the incidence of 'true' ITP as a primary disease is less common than has yet been suggested. Additionally, there is evidence that ITP itself predispose affected subjects toward development of other diseases.
What foods should you avoid with ITP?
Eat Less...Canned and frozen foods and leftovers. The nutritional value of food deteriorates with time.White flour, white rice and processed foods. ... Hydrogenated, partially hydrogenated or trans-fats. ... Sugar. ... Dairy products. ... Meat. ... Alcoholic beverages. ... Foods that can interfere with blood clotting.More items...
How long does ITP last?
ITP may be acute and resolve in less than 6 months, or chronic and last longer than 6 months. Treatment options include a variety of medications that can reduce the destruction of platelets or increase their production. In some cases, surgery to remove the spleen is necessary.
What causes platelet count to drop?
Platelet destruction A low platelet count can be a result of the body destroying too many platelets too quickly. Some reasons a body might destroy its platelets include : side effects of certain medications, including diuretics, some antibiotics, blood thinners, and anti-seizure medications. an enlarged spleen.
How to treat ITP?
Medications to treat ITP may include: 1 Steroids. Your doctor will likely start you on an oral corticosteroid, such as prednisone. Once your platelet count is back to a safe level, you can gradually discontinue taking the drug under the direction of your doctor. Long-term use of these medications isn't recommended because they can increase your risk of infections, high blood sugar and osteoporosis. 2 Immune globulin. If corticosteroids don't help, your doctor may give you an injection of immune globulin. This drug may also be used if you have critical bleeding or need to quickly increase your blood count before surgery. The effect usually wears off in a couple of weeks. 3 Drugs that boost platelet production. Medications such as romiplostim (Nplate) and eltrombopag (Promacta) help your bone marrow produce more platelets. These types of drugs can increase your risk of blood clots. 4 Other drugs. Rituximab (Rituxan, Truxima) helps increase your platelet count by reducing the immune system response that's damaging your platelets. But this drug also can reduce the effectiveness of vaccinations, which may be needed if you later choose surgery to remove your spleen.
What is the best treatment for ITP?
Medications to treat ITP may include: Steroids. Your doctor will likely start you on an oral corticosteroid, such as prednisone. Once your platelet count is back to a safe level, you can gradually discontinue taking the drug under the direction of your doctor.
What are some medications that can help with platelet function?
Examples include aspirin, ibuprofen (Advil, Motrin IB, others) and ginkgo biloba. Medications to treat ITP may include: Steroids.
What is the diagnosis of immune thrombocytopenia?
To diagnose immune thrombocytopenia, your doctor will try to exclude other possible causes of bleeding and a low platelet count, such as an underlying illness or medications you or your child may be taking.
What to do if you have thrombocytopenia?
If you have immune thrombocytopenia, try to: Avoid contact sports. Depending on your risk of bleeding, head impacts during sports like boxing, martial arts and football could cause bleeding in your brain. Talk to your doctor about what activities are safe for you. Watch for signs of infection.
Can you check platelets with blood?
Blood tests can check the levels of platelets. Rarely, adults might need a bone marrow exam to rule out other problems.
Can ITP cause bleeding?
Although rare, severe bleeding can occur with ITP. Emergency care usually includes transfusions of platelet concentrates. Steroids and immune globulin may also be given through a tube in a vein.
Diagnosing ITP
We begin the diagnosis by taking your complete medical history and performing a physical examination. Make sure to tell us about all of you (or your child's) symptoms.
ITP Treatment
Once we confirm a diagnosis, we will discuss the treatment plan with you. Learn about ITP treatment options at Stanford.
How is idiopathic thrombocytopenic purpura treated?
Specific treatment for idiopathic thrombocytopenic purpura will be determined by your health care provider based on:
What is immune thrombocytopenic purpura?
Immune thrombocytopenic purpura (ITP) is a blood disorder characterized by a decrease in the number of platelets in the blood. Platelets are cells in the blood that help stop bleeding. A decrease in platelets can cause easy bruising, bleeding gums, and internal bleeding. This disease is caused by an immune reaction against one's own platelets. It has also been called autoimmune thrombocytopenic purpura.
What causes idiopathic thrombocytopenic purpura?
In ITP, the immune system is stimulated to attack your body's own platelets. Most often this is a result of antibody production against platelets. In a small number of cases, a type of white blood cell called T-cells will directly attack platelets. This immune system error may be a result of any of the following:
What is the difference between purpura and thrombocytopenia?
Thrombocytopenia means a decreased number of platelets in the blood. Purpura refers to the purple discoloring of the skin, as with a bruise. ITP is a fairly common blood disorder that both children and adults can develop. There are two forms of ITP: Acute thrombocytopenic purpura.
How long does it take for ITP to go away?
There are two forms of ITP: Acute thrombocytopenic purpura. This usually affects young children, ages 2 to 6 years old. The symptoms may follow a viral illness, such as chickenpox. Acute ITP usually starts suddenly and the symptoms usually disappear in less than 6 months, often within a few weeks.
What is the normal platelet count for thrombocytopenic purpura?
What are the symptoms of idiopathic thrombocytopenic purpura? Normal platelet count is in the range of 150,000 to 450,000. With ITP, the platelet count is less than 100,000. By the time significant bleeding occurs, you may have a platelet count of less than 10,000.
How long does thrombocytopenic purpura last?
Chronic thrombocytopenic purpura. The onset of the disorder can happen at any age, and the symptoms can last a minimum of 6 months, several years , or a lifetime. Adults have this form more often than children do, but it does affect adolescents. Females have it more often than males.
What is an ITP?
Inspection & Test Plan (ITP) – An Inspection & Test Plan is the program of inspection, testing of materials, and survey shall be prepared and submitted by the contractor to the Engineer for approval before usage and application to the site.
What is ITP in project management?
ITP is one of the most important project documents that you need to provide for each activity and it must be prepared way ahead before the start of the activity.
Who submits the method statement and inspection and test plan?
As it is always required by the contract or specification, Method Statement and Inspection and Test Plan including Checklist shall be submitted to the Engineer for approval.
Who reviews inspection and test plans?
Inspection and Test Plan is made and issued by the Quality Engineer, it should then be reviewed by the Quality Manager, Construction Manager and approved by Project Manager before it shall submit to the Engineer.
What does S mean in inspection?
Surveillance ( S ) = random attendance at site, no signature required on the Inspection Request ( IR ) or its accompanying documentation.
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What Does Inspection and Test Plan (ITP) Mean?
An inspection and test plan, or inspection test plan, is a document or series of documents used for quality assurance purposes. An inspection and test plan outlines how the quality of a particular object will be ensured both at its beginning and throughout its service life.
Which industry uses inspection and test plans?
Another sector that uses inspection and test plans frequently is the oil and gas industry. Pipelines, for example, can be subject to corrosion because of the contents they carry. An inspection and test plan will dictate how often inspections will be conducted to prevent a pipeline failure.
Why do we need inspection and test plans?
Bridges, buildings and roads must be periodically inspected and tested to ensure that they are safe for their users or inhabitants.
What are the methods of inspection?
The inspection methods include ultrasonic testing, radiographic testing, visual inspection, pH testing and many others. The timing and frequency of these inspections are determined in the inspection and test plan.
What is an inspection test plan?
An inspection test plan is a project document that is usually prepared by the quality engineer. It sets down the program of inspections, tests, and surveys needed for each specified work or materials of the project. Having an inspection test plan protects the business from costly mistakes, and ensures the consistency and quality ...
Why is an inspection and test plan important?
Having an inspection test plan not only avoids poor quality work but prevents serious incidents from occurring. Make inspection test plans efficient by replacing paper forms with a digital template.
What does S mean in inspection?
Surveillance (S) – this means attendance on site can be random and that there is no need for signature on the inspection request or its accompanying documentation.
Where is the reference number on a test plan?
This is usually written in the last column of the form.
Who is involved in the inspection process?
In the inspection or verification section of the inspection test plan, the contractor, consultant or engineer, and client or employer will be involved. The parties involved should determine their responsibilities based on the inspection process criteria, and it should be done before works start, to avoid confusion and compromises. Below is the inspection process criteria for every inspection plan item:
Is it good practice to have a quality inspection and test plan?
It is good practice to have one prepared before starting the works as it will provide the construction business and its client a clear and concise plan in managing inspection and test activities that will provide quality assurance, control, and documented evidence of constructed works.
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Preparing For Your Appointment
- To diagnose immune thrombocytopenia, your doctor will try to exclude other possible causes of bleeding and a low platelet count, such as an underlying illness or medications you or your child may be taking. Blood tests can check the levels of platelets. Rarely, adults might need a bone marrow exam to rule out other problems.