Precautions
- nausea
- vomiting
- stomach area (abdominal) pain
- tiredness
- trouble breathing If you get any of these symptoms during treatment with Xigduo XR, if possible check for ketones in your urine, even if your blood sugar is less than ...
What is Xigduo XR used for?
- Fever or
- Infection of any type or
- Surgery (major) or
- Trauma—These conditions may cause temporary problems with blood sugar control and your doctor may treat you with insulin.
What conditions does Janumet XR treat?
To make sure Janumet is safe for you, tell your doctor if you have ever had:
- kidney disease (your kidney function may need to be checked before and while you are taking this medicine);
- liver disease;
- heart disease;
- pancreatitis;
- high triglycerides (a type of fat in the blood);
- gallstones; or
- alcoholism.
What is the alternative of Janumet?
Tradjenta
- Uses. The Food and Drug Administration (FDA) has approved both Januvia and Tradjenta to treat type 2 diabetes in adults, along with diet and exercise.
- Drug forms and administration. Januvia comes as a tablet that you swallow. ...
- Side effects and risks. Januvia and Tradjenta both work in the same way. ...
- Effectiveness. ...
- Costs. ...
What is Januvia used for and how does it work?
What are side effects of JANUMET XR?
Common side effects when taking JANUMET or JANUMET XR include stuffy or runny nose and sore throat, gas, upset stomach, indigestion, headache, upper respiratory tract infection, weakness, diarrhea, low blood sugar (hypoglycemia) when used in combination with certain medicines such as sulfonylurea or insulin, nausea and ...
Does JANUMET XR cause weight loss?
Some people who took Janumet and Janumet XR in clinical trials lost weight. So, it's possible that you may lose weight while taking Janumet or Janumet XR for type 2 diabetes. However, the drugs aren't typically prescribed for this purpose.
What is the difference between metformin and JANUMET XR?
Glucophage (metformin) Lowers your blood sugar. Janumet is a combination of two anti-diabetic medicines that work better together, but is available as brand only. Lowers blood sugar.
What is the best time of day to take JANUMET XR?
It is better to take JANUMET XR with your evening meal. Take JANUMET XR one time each day by mouth with a meal to help lower your chance of having an upset stomach. It is better to take JANUMET XR with your evening meal. Take JANUMET XR exactly as your doctor tells you.
Does Janumet cause kidney damage?
There have been postmarketing reports of worsening renal function in patients taking sitagliptin with or without metformin, including acute renal failure, sometimes requiring dialysis. Before initiating JANUMET or JANUMET XR and at least annually thereafter, renal function should be assessed.
How quickly does Janumet XR work?
The effect of Januvia (generic name: sitagliptin) on your blood sugar levels may begin quickly, within the first 1 to 2 weeks. You may start to see your blood sugar drop after just a few doses.
How long does it take for Janumet to lower blood sugar?
How quickly does Janumet (sitagliptin / metformin) work? Depending on the dose, the medication starts working within 4 to 5 days, but the full effects of Janumet (sitagliptin / metformin) can take up to a few weeks in lowering your blood sugar and improving your A1c level.
What happens if I stop taking Janumet?
Official answer. If you stop taking a diabetes medication without consulting your doctor first, your blood sugar will likely return to abnormally high levels. Uncontrolled high blood sugar can lead to serious health consequences over the long term, including: Heart disease.
Is it OK to take Janumet XR twice a day?
Take JANUMET XR orally once daily with a meal. Patients taking two JANUMET XR tablets should take the two tablets together once daily. Individualize the dosage of JANUMET XR on the basis of the patient's current regimen, effectiveness, and tolerability.
What is the safest diabetic medication?
by Drugs.com Most experts consider metformin to be the safest medicine for type 2 diabetes because it has been used for many decades, is effective, affordable, and safe. Metformin is recommended as a first-line treatment for type 2 diabetes by the American Diabetes Association (ADA).
Is a banana OK for diabetics?
Fruits like bananas are healthy foods that contain fiber, vitamins, and minerals. You can include bananas in your diet even if you have diabetes.
Is JANUMET the same as metformin?
Janumet is a combination of two drugs, metformin and sitagliptin, that are used for reducing blood glucose (sugar) levels in individuals with type 2 diabetes. The FDA approved Janumet in March 2007. Insulin is a hormone produced by the pancreas.
Does janumet cause loss of appetite?
Get medical help right away if you have any very serious side effects, including: signs of pancreatitis (such as nausea/vomiting that doesn't stop, loss of appetite, severe stomach/abdominal/back pain), lactic acidosis (see Warning section). A very serious allergic reaction to this drug is rare.
Is there a difference between Janumet and Janumet XR?
Janumet and Janumet XR are both prescription medications designed to be used along with diet and exercise to help control blood sugar levels in adults with type 2 diabetes. The difference is that Janumet is taken twice daily, while Janumet XR (extended-release) is taken only once daily.
What is the advantage of Janumet over metformin?
Cimetidine (Tagamet), by decreasing the elimination of metformin from the body, can increase the level of metformin in the blood by 40%.
Does metformin cause weight loss?
Is Metformin an Effective Weight Loss Pill? No. The amount of weight you're likely to lose is low. In one diabetes prevention study, 29% of people lost 5% or more of their body weight and just 8% lost around 10%.
Before Taking This Medicine
You should not use Janumet if you are allergic to metformin or sitagliptin (Januvia), or if you have severe kidney disease or diabetic ketoacidosis...
How Should I Take Janumet?
Take Janumet exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller...
Janumet Dosing Information
Usual Adult Dose of Janumet for Diabetes Type 2:Dose should be individualized based on patient's current regimen, effectiveness, and tolerability.M...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember (be sure to take the medicine with food). Skip the missed dose if it is almost time for your next sche...
What Happens If I Overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have severely low blood sugar (extreme weakness, nausea, t...
What Should I Avoid While Taking Janumet?
Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.See also: Janumet and alcohol (in more detail)
What Other Drugs Will Affect Janumet?
Many drugs can interact with metformin and sitagliptin. Some drugs can affect how well Janumet controls your blood sugar. Other drugs may increase...
How does janumet work?
Janumet is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Janumet is not used to treat type 1 diabetes.
What is Janumet?
Janumet contains a combination of metformin and sitagliptin. Metformin and sitagliptin are oral diabetes medicines that help control blood sugar levels.
How old do you have to be to use Janumet?
Janumet is not approved for use by anyone younger than 18 years old.
What medications should I take before taking Janumet?
Tell your doctor if you use any of the following medications before taking Janumet: anti-seizure medications (including topiramate, zonisamide, acetazolamide, phenytoin, and others) anti-viral medications for HIV or AIDS; antipsychotic medications (especially chlorpromazine, pro chlorperazine, thioridazine, and others);
Can Janumet cause pancreatitis?
Janumet may also lead to a serious condition called pancreatitis. Call your doctor right away if you have severe stomach pains with or without vomiting.
Does Janumet dissolve in the body?
Janumet tablets may not completely dissolve in the body. Part of the tablet may appear in your stool. This is a normal side effect of Janumet and will not make the medicine less effective. Call your doctor if you see a tablet in your stool several times.
Does Janumet cause a rash?
Janumet side effects. Get emergency medical help if you have signs of an allergic reaction to Janumet: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
What is metformin used for?
Sitagliptin / metformin is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.
Are you currently using Janumet XR?
This survey is being conducted by the WebMD marketing sciences department.
What is the drug JANUMET XR?
JANUMET XR tablets combine two antihyperglycemic agents with complementary mechanisms of action to improve glycemic control in adults with type 2 diabetes mellitus: sitagliptin, a dipeptidyl peptidase4 (DPP-4) inhibitor , and metformin hydrochloride extended-release, a member of the biguanide class .
When to discontinue JANUMET XR?
Discontinue JANUMET XR at the time of, or prior to, an iodinated contrast imaging procedure in patients with an eGFR between 30 and 60 mL/min/1.73 m 2; in patients with a history of liver disease, alcoholism, or heart failure; or in patients who will be administered intra-arterial iodinated contrast. Reevaluate eGFR 48 hours after the imaging procedure; restart JANUMET XR if renal function is stable [see WARNINGS AND PRECAUTIONS ].
How long does it take for a JANUMET XR to go steady state?
After administration of two JANUMET XR 50 mg/1000 mg tablets once daily with the evening meal for 7 days in healthy adult subjects, steady-state for sitagliptin and metformin is reached by Day 4 and 5 , respectively.
How much metformin is recommended for JANUMET XR?
The dose of JANUMET XR should be individualized on the basis of the patient’s current regimen, effectiveness, and tolerability while not exceeding the maximum recommended daily dose of 100 mg sitagliptin and 2000 mg metformin. Initial combination therapy or maintenance of combination therapy should be individualized and left to the discretion of the health care provider.
What is the name of the medication that is used in the treatment of diabetes?
JANUMET XR tablets contain two oral antidiabetic medications used in the management of type 2 diabetes: sitagliptin and metformin hydrochloride extended-release.
Can you split a junumet xr?
JANUMET XR should be administered with food to reduce the gastrointestinal side effects associated with the metformin component. JANUMET XR should be given once daily with a meal preferably in the evening. JANUMET XR should be swallowed whole. The tablets must not be split, crushed, or chewed before swallowing.
What is in Janumet XR?
JANUMET (JAN-you-met) tablets contain 2 prescription medicines: sitagliptin (JANUVIA ®) and metformin. Once-daily prescription JANUMET XR (JAN-you-met XR ) tablets contain sitagliptin (the medicine in JANUVIA ®) and extended-release metformin. JANUMET or JANUMET XR can be used along with diet and exercise to lower blood sugar in adults ...
Can JANUMET cause hives?
If you have an allergic reaction, stop taking JANUMET or JANUMET XR and call your doctor right away or get emergency medical help.
Can you stop JANUMET XR?
Tell your doctor if you are going to get an injection of dye or contrast agent for an x-ray procedure; JANUMET or JANUMET XR may need to be stopped for a short time.
Can Janumet and Janumet XR be crushed, split, or chewed?
No, Janumet and Janumet XR should not be crushed, split, or chewed. It’s best to swallow the tablets whole.
Is Janumet or Janumet XR a blood thinner?
No, Janumet and Janumet XR aren’t blood thinners. Blood thinners are drugs that help prevent or treat blood clots.
Are Janumet and Janumet XR harmful for your kidneys?
Possibly. Taking Janumet or Janumet XR may cause kidney issues, such as kidney failure. Kidney issues weren’t reported as side effects in clinical trials of Janumet and Janumet XR. However, this side effect has been reported since the drugs became available for use.
Is Janumet or Janumet XR taken for weight loss?
Janumet and Janumet XR aren’t currently approved for weight loss. The drugs are approved to treat type 2 diabetes when taken along with diet and exercise.
