Lymphocytic leukocytosis is an abnormally high number of lymphocytes (a type of white blood cell) in the blood. Lymphocytes are a type of white blood cell that play several roles in the immune system, including protection against bacteria, viruses, fungi, and parasites. There are three types of lymphocytes. B cells (B lymphocytes)
What are the causes of increased lymphocytes in leukocytosis?
The most common cause of lymphocytic leukocytosis is infection with a virus. Other causes include: Two blood cancers, lymphoma and lymphocytic leukemia, are associated with high numbers of lymphocytes in the bloodstream. Neutrophils, like lymphocytes, protect against bacteria, viruses, parasites, and fungal growth.
What are the treatment options for leukocytosis?
Leukocytosis treatments. The treatment for leukocytosis varies depending on the reason. Among the most prevalent therapeutic options are: antihistamines used to treat allergic reactions; Inhalers for asthma; antibiotics used to treat bacterial infections; Chemotherapy, radiation therapy, or stem cell transplantation for leukemia are examples of ...
What are the causes and treatment for leukocytosis?
Treatments for symptoms of the underlying conditions associated with leukocytosis may include:
- Antihistamines to reduce symptoms of inflammation
- Cold medicines to reduce sore throat, congestion, runny nose
- Tylenol (acetaminophen) or nonsteroidal anti-inflammatory drugs (NSAIDs) such as Advil (ibuprofen) or Aleve (naproxen) to reduce fever, swelling, and pain
- Steroids or other anti-inflammatory drugs to reduce inflammation
What causes high leukocytes?
Serious Causes
- Asthma
- Pregnancy
- Infections such as tuberculosis
- Tumors in the bone marrow
- Leukemia
- Inflammatory conditions, such as arthritis and bowel disease
- Tissue damage
What causes lymphocytosis leukocytosis?
This common type of leukocytosis is caused by an increase in neutrophils, which account for 40–60 percent of the white blood cells in your body. Lymphocytosis. This occurs when you have high levels of lymphocytes, which make up 20–40 percent of your white blood cells.
What happens if you have leukocytosis?
Leukocytosis means you have a high white blood cell count. This means you have more white blood cells than normal. Leukocytosis is a normal immune response and isn't always a cause for concern. Most of the time, it means that your body is fighting off infection or inflammation.
What is the difference between leukocytosis and lymphocytosis?
Leukocytosis in which neutrophils are elevated is neutrophilia; leukocytosis in which lymphocyte count is elevated is lymphocytosis; leukocytosis in which monocyte count is elevated is monocytosis; and leukocytosis in which eosinophil count is elevated is eosinophilia.
Is lymphocytosis serious?
You can have a higher than normal lymphocyte count but have few, if any, symptoms. It usually occurs after an illness and is harmless and temporary. But it might represent something more serious, such as a blood cancer or a chronic infection.
Can leukocytosis cause death?
Neutrophilic Leukocytosis It can cause a stroke or breathing problems that could lead to death. Doctors treat this syndrome by adding fluid to the blood and using drugs to reduce the neutrophils in the blood.
Is leukocytosis a leukemia?
Excessive numbers of white blood cells are most often due to the response of normal bone marrow to infection or inflammation. In some instances, leukocytosis is a sign of more serious primary bone marrow disease (leukemias or myeloproliferative disorders).
Can leukocytosis be cured?
Your WBCs may return to normal without treatment. Your healthcare provider will treat the cause of your leukocytosis. You may also need any of the following: IV fluids may be given to give you extra fluid and electrolytes.
What are the causes of lymphocytosis?
Common causes of reactive lymphocytosis: infections (EBV, CMV, pertussis, cat-scratch disease, HIV, etc.), drug reactions (DRESS), stress, and asplenia. Common causes of lymphocytosis secondary to monoclonal expansion: CLL/SLL, MBL (ALC under 5000 cells/microL), NHL (MZL, FL, MCL), T-LGL, HCL, Scezary syndrome.
What medications cause leukocytosis?
Among the most common medications causing leukocytosis are corticosteroids, lithium, and β-agonists. Also implicated are recombinant cytokines, antihypertensives, antifungals, antibiotics, anticonvulsants, antidiabetics, antidepressants, and others.
What is the treatment for lymphocytosis?
Immunotherapy is another complex procedure to treat severe cases of lymphocytosis. In immunotherapy, the drugs are used to help your immune system identify the cells and destroy these cells. Other forms of treatment include targeted cell therapy, stem cell therapy, etc.
What is an alarming lymphocyte count?
A count significantly higher than 3,000 lymphocytes in a microliter of blood is generally considered to be lymphocytosis in adults. In children, the threshold for lymphocytosis varies with age. It can be as high as 9,000 lymphocytes per microliter.
How do you reduce lymphocytosis?
Treatment optionsantiretroviral combination therapy for HIV.other antiviral agents, antibiotics, antifungals, or antiparasitic drugs to treat specific infections.gamma globulin to help prevent infections that can occur due to B-cell lymphocytopenia.bone marrow stem cell transplant.
What is the treatment for leukocytes?
Treatment for leukocytes in the urine depends on the cause and if there is an infection. For some conditions, such as a bacterial UTI, antibiotic therapy will clear up the infection relatively quickly. For more severe infections or those that will not resolve easily, more in-depth medical treatment may be needed.
What causes leukocytosis without infection?
Stressors capable of causing an acute leukocytosis include surgery, exercise, trauma, and emotional stress. Other nonmalignant etiologies of leukocytosis include certain medications, asplenia, smoking, obesity, and chronic inflammatory conditions.
Drugs Mentioned In This Article
Acute myeloid leukemia (AML) is a life-threatening disorder in which certain blood cells become cancerous and rapidly replace normal cells in the bone marrow. As normal blood cells are replaced by cancerous cells, people with AML become anemic from too few red blood cells.
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Overview
A high white blood cell count is also called leukocytosis. This means the numbers of white blood cells are higher than the normal range.
Test Details
White blood cells are measured in the number per microliter, and a “normal” count is generally a range. Different laboratories might use different ranges. In general, the normal range for men is 5,000-10,000 white blood cells per microliter of blood. For women who are not pregnant, the range is 4,500-11,000 white blood cells per microliter.
Results and Follow-Up
The following conditions can cause white blood cell counts to be high:
White Blood Cells
Although leukocytes are very important, they make up only about 1% of your blood. Like other blood cells, they are made in the bone marrow. They are being created all the time because most have a very short lifespan. Some live for less than a day.
How Is Leukocytosis Diagnosed?
Most of the time, doctors use a complete blood count (CBC) to check for leukocytosis. A CBC can be part of a routine physical, or your doctor might use it to help diagnose a specific illness. Another test, called a white blood cell differential or "diff," is sometimes done at the same time.
Lymphocytic Leukocytosis
Lymphocytes are an important part of the body's defense system. They protect against bacteria, viruses, parasites, and fungal growth. A high count of these cells is called lymphocytic leukocytosis. Lymphocytes come in three types: B cells, T cells, and natural killer cells.
Neutrophilic Leukocytosis
Neutrophils, like lymphocytes, protect against bacteria, viruses, parasites, and fungal growth. They also play a role in healing injuries. Myeloid leukemias can cause high neutrophil counts. If doctors find a high number of immature neutrophils in the blood, they may suspect leukemia.
Non-Malignant Causes of Leukocytosis
Disorders of the white blood cells can be malignant or non-malignant. The main non-malignant cause of leukocytosis is infection. A high white blood count most often signals an infection in the body, especially when there are also other symptoms.
Overview
Lymphocytosis is a higher-than-normal amount of lymphocytes, a subtype of white blood cells, in the body. Lymphocytes are part of your immune system and work to fight off infections.
Symptoms and Causes
Lymphocytosis results from increased numbers of lymphocytes in your blood. Lymphocytes are a type of white blood cell. They play an important role in your immune system, helping your body fight off infection. Many underlying medical conditions can cause lymphocytosis.
Diagnosis and Tests
Your doctor diagnoses lymphocytosis with a blood test called a complete blood count (CBC) with differential. This test shows an increase in white blood cells, with higher than normal amount of lymphocytes.
Management and Treatment
Doctors treat lymphocytosis by working to resolve its underlying cause. For most people, lymphocytosis goes away as the underlying condition improves.
Prevention
There is no way to prevent lymphocytosis. You can reduce your risk of viral infection by:
Living With
If you have a persistent infection or you experience chronic (ongoing) symptoms or symptoms that get worse over time, contact your doctor. Your doctor can determine if you have lymphocytosis during a complete medical examination.
Main Difference – Leukocytes vs Lymphocytes
Leukocytes and lymphocytes are found in the blood of vertebrates. Leukocytes are composed of granulocytes and agranulocytes. Three types of granulocytes are found in blood. They are neutrophils, eosinophils and basophils. Granulocytes are involved in the host defense through innate immunity.
What are Leukocytes
Leukocytes are the only type of nucleated cells found in blood, involved in the host defense by destroying pathogens which invade the body of vertebrates. They are generally called white blood cells. Leukocytes can be divided into two groups, depending on the presence of granules in their cytoplasm: granulocytes and agranulocytes.
What are Lymphocytes
Lymphocytes are the last type of leukocytes, involved mainly in the adaptive immunity by producing specific antibodies to a particular pathogen during host defense. During hematopoiesis, lymphocytes are differentiated from lymphoblastic stem cells. The three main types of lymphocytes are T lymphocytes, B lymphocytes and natural killer cells.
Difference Between Leukocytes and Lymphocytes
Leukocytes: Leukocytes refer to all the white blood cells in the blood.
