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what is lomotil used for in dogs

by Florine Kris Published 3 years ago Updated 2 years ago
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Diphenoxylate, also known as Logen®, Lomotil®, and Lonox®, is primarily used to treat diarrhea and colitis in dogs and cats. It also has anti-coughing properties. Diphenoxylate slows the gastrointestinal tract, decreases intestinal secretions and enhances absorption of liquids.Jul 18, 2015

Precautions

You can give 1/4 of a 2 mg or 2.5 mg tablet to her, up to twice a day. However, if there's an underlying cause to the diarrhea, such as parasites, etc, then she will need other medication that your veterinarian can prescribe. If there's no improvement after 2 or 3 doses, or if the diarrhea comes back after stopping the Lomotil, have her seen by your veterinarian ASAP, and bring a stool sample when you go.

How much Lomotil can I give my Dog?

While Lomotil can treat diarrhea, it’s most often used as a cough suppressant in dogs. Smaller toy breeds are predisposed to collapsing trachea, a condition whose symptoms include a persistent cough, Meeks says. Lomotil can help dry out the air passages and reduce the spasms that cause coughing.

Can you give Lomotil to a dog?

Yes Lomotil is more closely related to opioids than Imodium and may show up on drug tests. Bring your prescription with you when you get tested just to be safe. Lomotil doesn’t result penetrate the blood-brain barrier so if you want to get high off it, you have to take a whole lot.

Is Lomotil stronger than Imodium?

Most dogs have a cough suppressant effect from lmotil; it is generally effective at treating diarrhea. Her concern is that certain side effects associated with lomotil, such as Constipation in dogs and confusion in cat owners, may arise since it is also an antidiarrheal. How Fast Does Lomotil Work In Dogs?

Can I give my Dog Lomotil?

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How long does Lomotil take to work in dogs?

about 1 to 2 hoursThis medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow.

What is Lomotil prescribed for?

This medication is used to treat diarrhea. It helps to decrease the number and frequency of bowel movements. It works by slowing the movement of the intestines. Diphenoxylate is similar to opioid pain relievers, but it acts mainly to slow the gut.

What does diphenoxylate atropine do for dogs?

In dogs, diphenoxylate-atropine can be used to treat diarrhea or as a cough suppressant. The FDA (U.S. Food & Drug Administration) has approved this drug for use in humans but it is not officially approved for use in animals.

Does Lomotil stop diarrhea?

Lomotil (diphenoxylate/atropine) and Imodium (loperamide) are two antidiarrheal medications that are used to treat acute and chronic diarrhea. These medications work in similar ways to decrease the number and frequency of bowel movements.

Is Lomotil safe for dogs?

Diphenoxylate belongs to a class of drugs known as opiate agonists (morphine derivative). Diphenoxylate, also known as Logen®, Lomotil®, and Lonox®, is primarily used to treat diarrhea and colitis in dogs and cats.

Is Imodium and Lomotil the same thing?

Lomotil is typically used for acute diarrhea, but it may be used to treat chronic diarrhea as well. Imodium is used to treat both acute and chronic diarrhea. It can also be used to treat traveler's diarrhea (diarrhea from consuming contaminated food or water, usually when traveling to another country).

What is atropine used for in dogs?

Atropine is administered to block the effect of certain nervous system impulses (acetylcholine) on receptors throughout the body. In animals, like dogs and cats, it is most often used when an animal is undergoing anesthesia for surgery to block the undesirable effects of nervous system stimulation.

How do you stop a dog from having diarrhea?

A bland diet for 24 to 48 hours may help to resolve your pup's issue. Plain-cooked white rice with a little chicken and some canned plain pumpkin (not pumpkin pie filling) may help to make your pup's tummy feel better. Once your pooch feels better, gradually reintroduce their regular food.

How is colitis treated in dogs?

Non-specific treatment includes fasting for 24 to 48 hours, feeding a low residue or hypoallergenic diet, increasing dietary fiber content, and adding fermentable fiber such as psyllium, beet pulp, or fructooligosaccharides (FOS) to the food. Some dogs with colitis will do better on low-fiber diets.

When should Lomotil be taken?

Lomotil Tablet is a medication used to treat diarrhea. It manages symptoms of diarrhea such as stomach pain, cramping, and loose stools. Lomotil Tablet is taken with or without food at the dose and duration recommended by the doctor.

Why is Lomotil a narcotic?

Why is Lomotil (diphenoxylate / atropine) a controlled substance? Lomotil (diphenoxylate / atropine) is a controlled medication, because it contains diphenoxylate, which is an opioid medication. At smaller doses, it's used to treat diarrhea and does not cause pain-relieving effects like morphine at recommended doses.

Who should not take Lomotil?

Lomotil is contraindicated in pediatric patients less than 6 years of age due to the risks of severe respiratory depression and coma, possibly resulting in permanent brain damage or death (see CONTRAINDICATIONS). Lomotil has caused atropinism, particularly in pediatric patients with Down's syndrome (see PRECAUTIONS).

Why is Lomotil a narcotic?

Why is Lomotil (diphenoxylate / atropine) a controlled substance? Lomotil (diphenoxylate / atropine) is a controlled medication, because it contains diphenoxylate, which is an opioid medication. At smaller doses, it's used to treat diarrhea and does not cause pain-relieving effects like morphine at recommended doses.

Does Lomotil make you high?

In higher doses, however, like other narcotics, diphenoxylate can cause euphoria (elevation of mood) and physical dependence. In order to prevent abuse of diphenoxylate for its mood-elevating effects, atropine is combined with diphenoxylate in small quantities.

Who should not take Lomotil?

Lomotil is contraindicated in pediatric patients less than 6 years of age due to the risks of severe respiratory depression and coma, possibly resulting in permanent brain damage or death (see CONTRAINDICATIONS). Lomotil has caused atropinism, particularly in pediatric patients with Down's syndrome (see PRECAUTIONS).

Can you take Lomotil and Imodium at the same time?

Interactions between your drugs Using loperamide together with atropine may increase side effects such as dizziness, drowsiness, and difficulty concentrating.

What is the name of the drug that is used to treat diarrhea in dogs?

Brand Names for Diphenoxylate. Potential Side Effects of Diphenoxylate in Dogs. Dosing Information of Diphenoxylate for Dogs. Diphenoxylate belongs to a class of drugs known as opiate agonists (morphine derivative). Diphenoxylate , also known as Logen®, Lomotil®, and Lonox®, is primarily used to treat diarrhea and colitis in dogs and cats.

Can cats have diphenoxylate?

Diphenoxylate’s use in cats is controversial and should be avoided.

Can you give medication without consulting your veterinarian?

Medication should never be administered without first consulting your veterinarian.

How much diphenoxylate is in Lomotil?

Each Lomotil tablet contains: 2.5 mg of diphenoxylate hydrochloride USP (equivalent to 2.3 mg of diphenoxylate) and 0.025 mg of atropine sulfate USP (equivalent to 0.01 mg of atropine)

How long does it take for diarrhea to go away after taking lomotil?

If clinical improvement of chronic diarrhea after treatment with the maximum recommended daily dosage is not observed within 10 days, discontinue Lomotil as symptoms are unlikely to be controlled by further administration.

Can you take Lomotil with other drugs?

The concurrent use of Lomotil with other drugs that cause CNS depression (e.g., barbiturates, benzodiazepines, opioids, buspirone, antihistamines, muscle relaxants), may potentiate the effects of Lomotil (see WARNINGS). Either Lomotil or the other interacting drug should be chosen, depending on the importance of the drug to the patient. If CNS-acting drugs cannot be avoided, monitor patients for CNS adverse reactions. MAO Inhibitors Diphenoxylate may interact with monoamine oxidase inhibitors (MAOIs) and precipitate a hypertensive crisis. Avoid use of Lomotil in patients who take MAOIs and monitor for signs and symptoms of hypertensive crisis (headache, hyperthermia, hypertension).

Is lomotil safe for diarrhea?

Lomotil is contraindicated in patients with diarrhea associated with organisms that penetrate the GI mucosa ( toxigenic E. coli , Salmonella, Shigella ), and pseudomembranous enterocolitis (Clostridium difficile) associated with broad-spectrum antibiotics (see CONTRAINDICATIONS). Antiperistaltic agents, including Lomotil, slow gastrointestinal motility and may enhance bacterial overgrowth and the release of bacterial exotoxins. Lomotil has been reported to result in serious GI complications in patients with infectious diarrhea, including sepsis, prolonged and/or worsened diarrhea. Prolonged fever and the delay in the resolution of stool pathogens were reported in study of Shigellosis in adults who used Lomotil vs. placebo.

Can you take lomotil with electrolyte therapy?

The use of Lomotil should be accompanied by appropriate fluid and electrolyte therapy, when indicated. If severe dehydration or electrolyte imbalance is present, Lomotil should be withheld until appropriate corrective therapy has been initiated. Drug-induced inhibition of peristalsis may result in fluid retention in the intestine, which may further aggravate dehydration and electrolyte imbalance.

Is lomotil contraindicated for a 6 year old?

Cases of severe respiratory depression and coma, leading to permanent brain damage or death have been reported in patients less than 6 years of age who received Lomotil . Lomotil is contraindicated in patients less than 6 years of age due to these risks (see

Is diphenoxylate hydrochloride carcinogenic?

No long-term study in animals has been performed to evaluate carcinogenic potential. Diphenoxylate hydrochloride was administered to male and female rats in their diets to provide dose levels of 4 and 20 mg/kg/day throughout a three-litter reproduction study. At 50 times the human dose (20 mg/kg/day), female weight gain was reduced and there was a marked effect on fertility as only 4 of 27 females became pregnant in three test breedings. The relevance of this finding to usage of Lomotil in humans is unknown.

How does loperamide work?

Loperamide works by slowing the movement of the intestines. It may decrease intestinal secretions and may enhance mucosal absorption. The medication is absorbed from the gastrointestinal tract and metabolized by the liver.

What is imodium used for?

Overview of Loperamide (Imodium®) for Canines and Felines. Loperamide, commonly known as Imodium®, is used to treat diarrhea in cats and dogs. Loperamide is a synthetic piperidine derivative, a weak narcotic with antidiarrheal properties. Loperamide works by slowing the movement of the intestines.

Which is better, loperamide or diphenoxylate?

Some veterinarians feel that loperamide has a faster onset of action and longer duration of action than diphenoxylate (Lomotil®).

What happens if you overdose on loperamide?

Overdose of loperamide might result in nervous system stimulation or depression and respiratory distress.

What are the side effects of loperamide?

Adverse effects associated with loperamide include constipation, bloating, and sedation.

Does loperamide cause constipation?

Adverse effects associated with loperamide include constipation, bloating, and sedation. The use of loperamide in cats is controversial. Cats may react with excitatory behavior after receiving loperamide. Overdose of loperamide might result in nervous system stimulation or depression and respiratory distress.

Can loperamide be used for liver disease?

Use loperamide with caution in animals with head injuries, lung disease, acute abdominal pain or liver disease with associated neurologic abnormalities.

What is Lomotil?

Atropine affects the body in many different ways, such as reducing spasms in the bladder, stomach, and intestines.

How should I take Lomotil?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

What other drugs will affect Lomotil?

Using Lomotil with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, cold or allergy medicine, or medicine for anxiety, depression, or seizures.

Can you use lomotil for a purpose?

Lomotil may also be used for purposes not listed in this medication guide.

What is Lomotil?

Lomotil is a brand-name prescription drug that’s used to treat diarrhea. It’s prescribed as an add-on treatment for people who are still having diarrhea even though they’ve already been treated for it.

What is the only condition that both Lomotil and Imodium are used to treat?

Diarrhea is the only condition both Lomotil and Imodium are used to treat.

What is the name of the medication that slows down digestion?

Lomotil belongs to a class of medications called anti-diarrheals. It works by slowing down digestion in the stomach and also relaxes the digestive (stomach) muscles.

How long does diarrhea last with lomotil?

Lomotil is typically used to treat acute diarrhea. This is diarrhea that lasts for a short time (one to two days). Acute diarrhea may be related to a short-term illness such as a stomach bug. Lomotil can also be used to treat chronic diarrhea (lasting four weeks or longer).

What is the drug used to treat depression?

Monoamine oxidase inhibitors (MAOIs) such as isocarboxazid (Marplan) or phenelzine (Nardil) are used to treat depression. Diphenoxylate, an ingredient in Lomotil, interacts with these drugs and can cause hypertensive crisis (extremely high blood pressure).

Is Lomotil a brand name?

Lomotil tablets are available as a brand-name and a generic medication. The generic version is called diphenoxylate/atropine, and it also comes as a liquid solution you take by mouth. Lomotil contains two active drug ingredients: diphenoxylate and atropine. Neither drug is available as a generic on its own.

Is lomotil a digestive medication?

This type of diarrhea may be related to a digestive (stomach) condition. Lomotil comes as an oral tablet. It’s approved for use in adults and children ages 13 years and older. Lomotil belongs to a class of medications called anti-diarrheals . It contains two active drugs: diphenoxylate and atropine.

What is the best treatment for tracheal collapse in dogs?

Treatment of tracheal collapse is first geared toward medical management with anti-inflammatory steroids, cough suppressants, and sedation as needed. Bronchodilators are commonly used but likely show minimal benefit with solely tracheal disease present. Prednisone is often the first line corticosteroid ...

What breed of dog has a tracheal collapse?

Tracheal collapse is most common in middle aged to older small breed dogs with the Yorkshire terrier, Pug, Chihuahua, Poodle, and Maltese being over represented. The condition can be congenital but is often caused by progressive generative changes of the tracheal cartilages (tracheomalacia) leading to a loss of tracheal integrity ...

What breed of dog has a collapsed trachea?

Collapsing trachea is a debilitating respiratory disease process recognized predominately in miniature or toy breeds (Pomeranian, miniature and toy poodle, Yorkshire terrier, Chihuahuas, pug). The condition is reported in dogs of all ages, with the average being 7 years.

Can a dog have an intraluminal tracheal stent?

Intraluminal tracheal stents are best reserved for dogs with tracheal collapse that are not good candidates for extraluminal prosthesis and have failed medical therapy. They can be placed in dogs with intra thoracic tracheal collapse.

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Lomotil Description

This medication is used to treat diarrhea.

May Treat: Diarrhea

Drug Class: Antidiarrheal Antiperistaltic-Anticholinergic Combinations

Availability: Prescription Required

Pregnancy: Consult a doctor before using

Lactation: Consult a doctor before using

May Treat: Diarrhea

Drug Class: Antidiarrheal Antiperistaltic-Anticholinergic Combinations

Availability: Prescription Required

Pregnancy: Consult a doctor before using

Lactation: Consult a doctor before using

Alcohol: Limit intake while taking this medication

Driving: May cause drowsiness or dizziness. Use caution

Manufacturer: PFIZER US PHARM

Precautions

  • Do not use in kids less than 6.
  • May make you drowsy or dizzy. Drive with caution
  • Drink plenty of fluids

  • Do not use in kids less than 6.
  • May make you drowsy or dizzy. Drive with caution
  • Drink plenty of fluids
  • Reduce or avoid drinking alcohol
  • Review all drugs you are taking with your doctor
  • Call doctor if diarrhea lasts more than 2 days
  • For liquid products : Contains alcohol. Measure dose using a dosing spoon/cup/syringe.
  • For tablet products : May be habit forming. Call Dr before increasing dose or frequency.

Lomotil - Clinical Pharmacology

Indications and Usage For Lomotil

Contraindications

Warnings

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Each Lomotil tablet contains: 2.5 mg of diphenoxylate hydrochloride USP (equivalent to 2.3 mg of diphenoxylate) and 0.025 mg of atropine sulfate USP (equivalent to 0.01 mg of atropine) Diphenoxylate hydrochloride, an antidiarrheal, is ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate monohydrochloride an…
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Precautions

  • Diphenoxylate is rapidly and extensively metabolized in man by ester hydrolysis to diphenoxylic acid (difenoxine), which is biologically active and the major metabolite in the blood. After a 5 mg oral dose of carbon-14 labeled diphenoxylate hydrochloride in ethanolic solution was given to three healthy volunteers, an average of 14% of the drug plus its metabolites was excreted in the …
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Adverse Reactions

  • Lomotil is indicated as adjunctive therapy in the management of diarrhea in patients 13 years of age and older.
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Drug Abuse and Dependence

  • Lomotil is contraindicated in: 1. Pediatric patients less than 6 years of age due to the risks of respiratory and central nervous system (CNS) depression (see WARNINGS). 2. Patients with diarrhea associated with pseudomembranous enterocolitis (Clostridium difficile) or other enterotoxin-producing bacteria due to the risk of gastrointestinal (GI) complications, including s…
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Overdosage

  • Respiratory and/or CNS Depression in Pediatric Patients Less Than 6 Years of Age
    Cases of severe respiratory depression and coma, leading to permanent brain damage or death have been reported in patients less than 6 years of age who received Lomotil. Lomotil is contraindicated in patients less than 6 years of age due to these risks (see CONTRAINDICATION…
  • Anticholinergic and Opioid-Toxicities
    Toxicities associated with the atropine and diphenoxylate components of Lomotil have been reported. The initial presenting symptoms may be delayed by up to 30 hours due to prolonged gastric emptying time induced by diphenoxylate hydrochloride. Clinical presentations vary in ter…
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