Precautions
Officially, Metrogel is only indicated for the papules and pustules of rosacea – this is what it was tested against. Some users of Metrogel do find a reduction in redness as a result of the anti-inflammatory actions of metronidazole, but you should probably consider this a bonus rather than a given. Interesting Research
Does Metrogel really help with rosacea?
MetroGel is a prescription medicine used to treat the symptoms of Rosacea. MetroGel may be used alone or with other medications. MetroGel belongs to a class of drugs called Antibacterials, Topical.
What is Metrogel used for?
The most common side effects of Metrogel Vaginal include:
- vaginal itching or discharge,
- menstrual pain,
- breast pain,
- headache,
- rash,
- nausea,
- diarrhea, and
- cold symptoms such as stuffy nose, sneezing, or sore throat
What are the side effects of Metrogel vaginal?
metrogel The good news is that Tetracycline antibiotics will help both acne and rosacea (and it is possible you have both conditions at the same time). It is not unusual for acne or rosacea to get worse before it gets better, when you start a new brand of antibiotics. They usually take about 4 months to work so don't give up too soon.
Does Metrogel help acne?
See more
What bacteria does MetroGel treat?
METROGEL-VAGINAL is indicated in the treatment of bacterial vaginosis (formerly referred to as Haemophilus vaginitis, Gardnerella vaginitis, nonspecific vaginitis, Corynebacterium vaginitis, or anaerobic vaginosis).
What is MetroGel VAG gel used for?
This medication is used to treat certain types of bacterial infections in the vagina. Metronidazole is an antibiotic that works by stopping the growth of bacteria.
Who should not use MetroGel?
You should not use this medicine if you are taking or have taken disulfiram (Antabuse®) within the last 2 weeks. Disulfiram is used to help people who have a drinking problem. If these 2 medicines are taken close together, serious unwanted effects may occur.
What infections does metronidazole treat?
Metronidazole capsules and tablets are used to treat infections of the reproductive system, gastrointestinal (GI) tract, skin, heart, bone, joint, lung, blood, nervous system, and other areas of the body. Metronidazole capsules and tablets are also used to treat sexually transmitted diseases (STDs).
What causes bacterial vaginosis?
BV is a result of an imbalance of “good” and “harmful” bacteria in a vagina. Douching, not using condoms, and having new or multiple sex partners can upset the normal balance of vaginal bacteria, increasing your risk for getting BV.
How long does bacterial vaginosis last?
While the infection may go away on its own, most doctors use antibiotics to treat it. You may have been prescribed pills or vaginal cream. With treatment, bacterial vaginosis usually clears up in 5 to 7 days.
What are the side effects of MetroGel?
Stinging, burning, skin irritation, dryness, redness, metallic taste, nausea, or headache may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Why do you have to use metronidazole at bedtime?
Metronidazole vaginal gel is used to treat bacterial vaginosis. Use one applicatorful at bedtime. A usual course of treatment lasts for five nights....What is metronidazole vaginal gel used for?Type of medicineAn antibacterial gelUsed forTreatment of bacterial vaginosisAlso calledZidoval®1 more row•May 20, 2020
How long can you use MetroGel for?
If you're prescribed metronidazole cream or gel for rosacea, you'll normally use it twice a day for about 2 months. Treatment can sometimes last longer. Follow the instructions from your doctor or pharmacist.
Why would a doctor prescribe metronidazole?
It's used to treat skin infections, rosacea and mouth infections, including infected gums and dental abscesses. It's also used to treat conditions such as bacterial vaginosis and pelvic inflammatory disease.
How fast does metronidazole gel work?
Metronidazole gel provides quick relief from BV, and starts to clear up symptoms in 2 to 3 days. Even if your symptoms have cleared up, you must complete your entire course of treatment to make sure the infection is completely cleared.
What should be avoided when taking in metronidazole?
Do not take metronidazole if you have taken disulfiram (Antabuse®) within the last 2 weeks. Using these medicines together may cause serious unwanted effects. Drinking alcoholic beverages while using this medicine may cause stomach pain, nausea, vomiting, headache, or flushing or redness of the face.
How fast does Metrogel work for BV?
For bacterial vaginosis (BV) you will normally be prescribed a seven-day course of antibiotics where you will take one tablet, twice a day. At the end of this period, all symptoms of BV should have cleared up, although you will probably notice an improvement after only a couple of days.
Is bacterial vaginosis a STD?
BV isn't considered a sexually transmitted disease (STD). But the chances of getting it seem to go up with the number of sexual partners a woman has.
How do you know when metronidazole gel is working?
Metronidazole starts to work 1 to 2 hours after you take it, because it is quickly absorbed, and it reaches its maximum concentration after 20 minutes to 3 hours. But it may take a couple of days before you start to feel better or notice an improvement in your symptoms.
When do you apply Metrogel?
Apply and rub in a thin film of METROGEL® Topical Gel twice daily, morning and evening, to entire affected areas after washing. Areas to be treated should be cleansed before application of METROGEL® (metronidazole topical gel) Topical Gel. Patients may use cosmetics after application of METROGEL® Topical Gel.
How long does it take for Metrogel (metronidazole) to work?
You should notice significant improvement in your symptoms in about 3 to 4 weeks.
Can you apply moisturizer after Metrogel (metronidazole)?
You can use makeup while using this medication. Only use water based products and apply lightly. You may also be able to use sunscreens or moisturi...
Is Metrogel (metronidazole) safe?
You should not use Metrogel (metronidazole) if you are allergic to it. To make sureMetrogel (metronidazole) is safe for you, tell your doctor about...
Is Metrogel (metronidazole) safe during pregnancy?
This drug should be used during pregnancy only if clearly needed.
What is Metrogel used for?
MetroGel is a prescription medicine used to treat the symptoms of Rosacea. MetroGel may be used alone or with other medications.
How old are people treated with metronidazole?
Sixty-six subjects aged 65 years and older were treated with metronidazole gel, 1% in the clinical study. No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out.
How much metronidazole is in a gram of methylparaben?
METROGEL is an aqueous gel; each gram contains 10 mg of metronidazole in a base of betadex, edetate disodium, hydroxyethyl cellulose, methylparaben, niacinamide, phenoxyethanol, propylene glycol, propylparaben and purified water.
How much does methylimidazole weigh?
Metronidazole has a molecular weight of 171.16. It is a white to pale yellow crystalline powder. It is slightly soluble in alcohol and has solubility in water of 10 mg/mL at 20°C. Metronidazole belongs to the nitroimidazole class of compounds.
What are the adverse reactions to metronidazole?
The following adverse reaction has been identified during post approval use of topical metronidazole: peripheral neuropathy. Because this reaction is reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate the frequency or establish a causal relationship to drug exposure.
Does metronidazole prolong prothrombin time?
Oral metronidazole has been reported to potentiate the anticoagulant effect of coumarin and warfarin, resulting in a prolongation of prothrombin time. Drug interactions should be kept in mind when METROGEL (metronidazole) is prescribed for patients who are receiving anticoagulant treatment, although they are less likely to occur with topical metronidazole administration because of low absorption.
Does Metrogel cause burning?
MetroGel may cause serious side effects including: severe stinging or burning. Get medical help right away, if you have any of the symptoms listed above. The most common side effects of MetroGel include: mild burning or stinging, numbness or tingly feeling in your hands or feet, mild skin redness or irritation, dry, scaly, or itchy skin,
What is Metrogel (metronidazole)?
Metrogel (metronidazole) is used to lower the swelling and redness caused by rosacea.
How much does Metrogel cost?
Prices for Metrogel (metronidazole) start at just $ 48.75 with a GoodRx coupon. They’re fast, easy-to-use and free!
What are the side effects of Metrogel (metronidazole)?
With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.
How much does Metrogel (metronidazole) cost?
Metrogel (metronidazole) is available as a generic medication and may be significantly cheaper compared to the brand version. Unless there is a specific reason you need the brand, the generic medication will be a better value. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price.
What is metronidazole used for in cats?
Also known as Flagyl, metronidazole is commonly prescribed as a cat antibiotic used to treat intestinal infections, diarrhea, and other bacterial infections. Learn more about how metronidazole works, typical doses, and side effects in this cat medication guide from GoodRx.
Can Metrogel cause eye irritation?
EYE IRRITATION. Metrogel (metronidazole) can cause tearing and irritation of the eye. Wash your hands thoroughly before and after using Metrogel (metronidazole) and avoid contact with the eyes. In case of contact with eyes, wash out immediately with water.
Can you take Metrogel if you are allergic to it?
You should not use Metrogel (metronidazole) if you are allergic to it. To make sureMetrogel (metronidazole) is safe for you, tell your doctor about all your medical conditions and allergies. Metrogel (metronidazole) is not expected to harm an unborn baby.
What is rosacea medication used for?
Uses. This medication is used on the skin to treat a certain skin disorder known as rosacea, a type of adult acne. It may help to decrease redness, swelling and the number of pimples caused by rosacea.This medication is an antibiotic.
How long does it take for a syringe to work?
It may take about three weeks before any improvement is seen, and up to nine weeks for full benefit. If no improvement is seen after three weeks, consult your doctor. Stinging, burning, skin irritation, dryness, redness, metallic taste, nausea, or headache may occur.
Can you take metronidazole if you are allergic to it?
Before using metronidazole, tell your doctor or pharmacist if you are allergic to it; or to other nitroimidazole antibiotics (such as tinidazole ); or to other ingredients in this product; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Are you currently using Metrogel Gel With Pump?
This survey is being conducted by the WebMD marketing sciences department.
How much metronidazole is in a day?
Following single and multiple 5 gram doses of metronidazole vaginal gel to 4 patients with bacterial vaginosis, a mean maximum serum metronidazole concentration of 214 ng/mL on day 1 and 294 ng/mL (range: 228 to 349 ng/mL) on day five were reported. Steady state metronidazole serum concentrations following oral dosages of 400 to 500 mg BID have been reported to range from 6,000 to 20,000 ng/mL.
What is the formula for metronidazole?
Chemically, metronidazole is a 2-methyl-5-nitroimidazole-1-ethanol. It has a chemical formula of C 6 H 9 N 3 O 3, a molecular weight of 171.16, and has the following structure: METROGEL-VAGINAL is a gelled, purified water solution, containing metronidazole at a concentration of 7.5 mg/g (0.75%).
What is the intravaginal dosage form of metronidazole?
METROGEL- VAGINAL is the intravaginal dosage form of the synthetic antibacterial agent, metronidazole, USP at a concentration of 0.75%. Metronidazole is a member of the imidazole class of antibacterial agents and is classified therapeutically as an antiprotozoal and antibacterial agent.
Is metronidazole carcinogenic?
Metronidazole has shown evidence of carcinogenic activity in a number of studies involving chronic oral administration in mice and rats. Prominent among the effects in the mouse was the promotion of pulmonary tumorigenesis. This has been observed in all six reported studies in that species, including one study in which the animals were dosed on an intermittent schedule (administration during every fourth week only). At very high dose levels (approximately 500 mg/kg/day), there was a statistically significant increase in the incidence of malignant liver tumors in males. Also, the published results of one of the mouse studies indicate an increase in the incidence of malignant lymphomas as well as pulmonary neoplasms associated with lifetime feeding of the drug. All these effects are statistically significant. Several long-term oral dosing studies in the rat have been completed. There were statistically significant increases in the incidence of various neoplasms, particularly in mammary and hepatic tumors, among female rats administered metronidazole over those noted in the concurrent female control groups. Two lifetime tumorigenicity studies in hamsters have been performed and reported to be negative.
Can you drink alcohol while taking metronidazole?
The patient should be cautioned about drinking alcohol while being treated with metronidazole vaginal gel. While blood levels are significantly lower with METROGEL-VAGINAL than with usual doses of oral metronidazole, a possible interaction with alcohol cannot be excluded.
Can you take metronidazole vaginal gel?
Accordingly, for such patients, metronidazole vaginal gel should be administered cautiously.
Is metronidazole administered vaginally?
Data from well-controlled trials directly comparing metronidazole administered orally to metronidazole administered vaginally are not available.
How long does it take for a metronidazole to cause a reaction?
The reaction includes flushing, headache, nausea, vomiting, sweating, and increased thirst. The reaction can last from 30 minutes to several hours.
How should I use this medicine?
Do not take by mouth or apply to other areas of the body. Follow the directions on the prescription label. Wash hands before and after use. Screw the applicator to the tube and squeeze the tube gently to fill the applicator. Lie on your back, part and bend your knees. Insert the applicator tip high in the vagina and push the plunger to release the gel into the vagina. Gently remove the applicator. Wash the applicator well with warm water and soap. Use at regular intervals. Finish the full course pre scribed by your doctor or health care professional even if you think your condition is better. Do not stop using except on the advice of your doctor or health care professional.
What medicines prolong QT interval?
other medicines that prolong the QT interval (cause an abnormal heart rhythm) like dofetilide, ziprasidone
What is the use of metronidazole?
Metronidazole topical (for the skin) is used to treat skin lesions caused by rosacea.
What happens if you take metronidazole?
Call your doctor at once if you have: numbness, tingling, or burning pain in your hands or feet; or. stinging or burning when you apply metronidazole topical. Common side effects may include: burning or stinging; skin redness or irritation; dry, scaly, or itchy skin; or. cold symptoms such as stuffy nose, sneezing, sore throat.
How to wash your skin before applying metronidazole?
Wash and gently dry your skin before applying metronidazole topical
How old do you have to be to take Metronidazole?
Metronidazole topical is not approved for use by anyone younger than 18 years old.
Can you take metronidazole if you are allergic to it?
You should not use metronidazole topical if you are allergic to it.
Can metronidazole be used in your eyes?
Avoid getting metronidazole topical in your eyes.
What is metronidazole?
Metronidazole is an antibiotic that is used to treat bacterial infections of the vagina, stomach, liver, skin, joints, brain and spinal cord, lungs, heart, or bloodstream.
How is metronidazole taken?
Metronidazole oral is taken by mouth. The injection is given as an infusion into a vein. A healthcare provider will give you the injection if you are unable to take the medicine by mouth.
What should I avoid while using metronidazole?
While taking metronidazole and for 3 days after your last dose: Do not drink alcohol or consume foods, medicines, or other products that contain alcohol or propylene glycol. You may have unpleasant effects such as headaches, nausea, vomiting, stomach cramps, and warmth or tingling under your skin.
What other drugs will affect metronidazole?
Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.
How long after stopping metronidazole can you drink alcohol?
Do not drink alcohol or consume foods or medicines that contain propylene glycol while you are taking metronidazole and for at least 3 days after you stop taking it.
How long does metronidazole last?
Metronidazole is usually given for up to 10 days in a row. You may need to repeat this dosage several weeks later.
How long after taking metronidazole can you breastfeed?
You should not breastfeed within 24 hours after using metronidazole. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby. Metronidazole is not approved for use in children younger than 12 years old, or in girls who have not begun having menstrual periods.
