What is nateglinide (Starlix)?
What is nateglinide (Starlix)? Nateglinide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. This medicine is not for treating type 1 diabetes. Other diabetes medicines are sometimes used in combination with nateglinide if needed.
What class of drug is Nateglinide?
Nateglinide belongs to a class of drugs called meglitinides. Nateglinide helps your body regulate the amount of glucose (sugar) in your blood.
Is Nateglinide safe for diabetics?
Nateglinide was approved by the Food and Drug Administration in 2000 for manufacture by Novartis. Nateglinide shouldn't be used in people with type 1 diabetes (the body doesn't produce any insulin) or diabetic ketoacidosis (a dangerous condition that can occur if high blood sugar is untreated).
Can I take Nateglinide If I am pregnant or breastfeeding?
Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby. You should not breastfeed while using this medicine. Nateglinide is not approved for use by anyone younger than 18 years old. What are the side effects of Nateglinide (Starlix)?
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What are side effects of nateglinide?
Nateglinide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:headache.nasal congestion.runny nose.joint aches.back pain.constipation.cough.flu-like symptoms.
How long does it take for nateglinide to work?
Take nateglinide up to 30 minutes before each of your three main meals....About nateglinide.Type of medicineAn antidiabetic medicineAvailable asTablets2 more rows•Aug 12, 2020
Can you take nateglinide after eating?
This is a very important part of controlling your condition, and is necessary if the medicine is to work properly. Also, exercise regularly and test for sugar in your blood or urine as directed. Take this medicine 1 to 30 minutes before a meal. If you skip a meal, then you should also skip your dose of nateglinide.
What is the generic name for nateglinide?
Starlix (nateglinide) is available as a generic medication and may be significantly cheaper compared to the brand version.
Does nateglinide cause weight gain?
Weight Gain Patients treated with STARLIX had statistically significant mean increases in weight compared to placebo. In clinical trials, the mean weight increases with STARLIX 60 mg (3 times daily) and STARLIX 120 mg (3 times daily) compared to placebo were 1.0 kg and 1.6 kg respectively.
Does nateglinide cause blurred vision?
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, gout. You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar.
Is nateglinide A insulin?
Nateglinide is an insulinotropic agent that restores the physiological pattern of insulin secretion lost in T2DM in a transient and glucose-sensitive manner and thus can control glucose mealtime excursions.
Can nateglinide cause hypoglycemia?
This medicine may cause hypoglycemia (low blood sugar). This is more common when this medicine is taken together with certain medicines. Low blood sugar must be treated before it causes you to pass out (unconsciousness).
When should I take Starlix?
The recommended dose of STARLIX is 120 mg orally three times daily before meals. The recommended dose of STARLIX is 60 mg orally three times daily before meals in patients who are near glycemic goal when treatment is initiated. Instruct patients to take STARLIX 1 to 30 minutes before meals.
Is nateglinide fast acting?
Abstract. Nateglinide is a fast-acting insulin secretion agent that specifically targets postprandial hyperglycemia in patients with type 2 diabetes.
Is metformin good for weight loss?
Conclusion: Metformin is an effective drug to reduce weight in a naturalistic outpatient setting in insulin sensitive and insulin resistant overweight and obese patients.
What does Starlix do?
Nateglinide is used alone or with other medications to control high blood sugar along with a proper diet and exercise program. It is used in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.
How much does nateglinide lower blood sugar?
The blood glucose-lowering capacity of nateglinide is added to that of these medications and yields an overall potential HbA1c reduction of 1.8 to 2.5%.
What is the single advantage of nateglinide over glibenclamide?
Comparative preclinical studies in vitro indicate that nateglinide inhibits KATP channels more rapidly, and with a shorter duration of action, than glibenclamide, glimepiride and repaglinide, and shows a greater degree of specificity for SUR1 over SUR2, as compared with glibenclamide and repaglinide.
What is the mechanism of action of nateglinide?
Mechanism Of Action Nateglinide is an amino-acid derivative that lowers blood glucose levels by stimulating insulin secretion from the pancreas. This action is dependent upon functioning beta-cells in the pancreatic islets. Nateglinide interacts with the ATP-sensitive potassium (K+ATP) channel on pancreatic beta-cells.
Can nateglinide cause hypoglycemia?
This medicine may cause hypoglycemia (low blood sugar). This is more common when this medicine is taken together with certain medicines. Low blood sugar must be treated before it causes you to pass out (unconsciousness).
What is natellinide used for?
Nateglinide is used alone or in combination with other medications to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood) in people whose diabetes cannot be controlled by diet and exercise alone. Nateglinide belongs to a class of drugs called meglitinides. ...
What to do if you forget to take Nateglinide?
Before you start taking nateglinide, ask your doctor what to do if you forget to take a dose. Write these directions down so you can refer to them later. As a general rule, if you have just begun to eat a meal, take the missed dose as soon as you remember it.
How should this medicine be used?
Nateglinide comes as a tablet to take by mouth. It is usually taken three times daily. Take nateglinide any time from 30 minutes before a meal to just before the meal. If you skip a meal, you need to skip the dose of nateglinide. If you add a meal, add a dose of nateglinide. Your doctor may gradually increase your dose, depending on your response to nateglinide. Monitor your blood glucose closely. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take nateglinide exactly as directed. Do not take more or less of it or take it more often than directed by the package label or prescribed by your doctor.
What should I know about storage and disposal of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
What to do if you are allergic to nateglinide?
tell your doctor and pharmacist if you are allergic to nateglinide or any other drugs.
How to dispose of unneeded medication?
However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
Can you get pregnant while taking Nateglinide?
If you become pregnant while taking nateglinide, call your doctor. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking nateglinide. tell your doctor if you have fever, infection, injury, or illness with vomiting or diarrhea. These may affect your blood sugar level.
What is Nateglinide used for?
It is used in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.
How to report nateglinide side effects in Canada?
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Precautions. Before taking nateglinide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
Why do you need to check the labels on cough and cold?
Check the labels on all your nonprescription medicines (such as cough -and-cold products) because they may contain ingredients that could affect your blood sugar. Ask your pharmacist about the safe use of those products.
Can Nateglinide cause low blood sugar?
Nateglinide can cause low blood sugar ( hypoglycemia) especially if you are taking other medicines for diabetes. Consuming large quantities of alcohol, not getting enough calories from food, or doing unusually heavy exercise may also lead to low blood sugar.
What is nateglinide used for?
What is nateglinide, and how does it work (mechanism of action)? Nateglinide is an oral drug used to lower blood sugar (glucose) levels in type 2 diabetes. It is in a class of drugs called meglitinides which also includes repaglinide ( Prandin ). Approximately 90% of patients with diabetes have type 2 diabetes.
When was Nateglinide approved?
Nateglinide was approved by the FDA in December 2000.
What are the side effects of nateglinide?
Another important side effect of nateglinide therapy is hypoglycemia ( low blood glucose levels with or without symptoms) can occur.
Where to report negative side effects of nateglinide?
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088. See more info: nateglinide on RxList. Medically Reviewed on 11/8/2019.
Can you take Nateglinide while pregnant?
Nateglinide should not be used during pregnancy. No safety and efficacy studies have been conducted in pregnant women taking nateglinide. Since many drugs are excreted in breast milk, the manufacturer recommends that nateglinide not be administered to nursing mothers.
Does MedicineNet provide medical advice?
MedicineNet does not provide medical advice, diagnosis or treatment. See additional information.
Does Nateglinide cause high glucose levels?
This leads to high levels of blood glucose. Nateglinide stimulates cells in the pancreas to produce insulin in a manner similar to the class of drugs called sulfonylureas, for example, glyburide (Diabeta, Glynase and Micronase), which also are used in type 2 diabetes.
What is nateglinide used for?
Nateglinide is used to lower blood sugar in patients with high blood sugar (diabetes).
How is nateglinide best taken?
Use nateglinide as ordered by your doctor. Read all information given to you. Follow all instructions closely.
Can you take Nateglinide if you feel well?
Keep taking nateglinide as you have been told by your doctor or other health care provider, even if you feel well.
Can nateglinide cause seizures?
Low blood sugar may happen with nateglinide. Very low blood sugar can lead to seizures, passing out, long lasting brain damage, and sometimes death. Talk with the doctor.
Who to talk to about Nateglinide?
Check with your pharmacist. If you have any questions about nateglinide, please talk with your doctor, nurse, pharmacist, or other health care provider.
Can nateglinide cause low blood sugar?
Low blood sugar can happen. The chance may be raised when nateglinide is used with other drugs for diabetes . Signs may be dizziness, headache, feeling sleepy or weak, shaking, fast heartbeat, confusion, hunger, or sweating. Call your doctor right away if you have any of these signs. Follow what you have been told to do for low blood sugar. This may include taking glucose tablets, liquid glucose, or some fruit juices.
How does Nateglinide work?
This way, it also helps to prevent kidney damage, blindness, loss of limbs, nerve problems, and sexual dysfunctions. It also reduces the risk of experiencing heart attacks and strokes. It works by stimulating the body to produce increased amounts of insulin to reduce blood sugar levels. This medication is administered orally, and is available in the form of tablets.
Does Lybrate take responsibility for any medication?
Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
Can you take Nateglinide if you are allergic to it?
Do not take Nateglinide if you are allergic to any of its components. Inform your doctor of your allergies.
Does Nateglinide cause weight gain?
Weight gain is an observed side effect of Nateglinide. You must monitor your blood sugar levels regularly, so that your physician is able to regulate your dosage as per your body’s needs. Nateglinide can cause low blood sugar especially if used in a combination with other medicines. Increased consumption of alcohol, decreasing the number of calories obtained from food, and doing uncommonly heavy exercises without taking in the required amount of calories can also result in low blood sugar levels. Symptoms include chills, dizziness, weakness, headaches, fast heartbeat and hunger.
Is glynase MF the same as glycomet GP?
Hello, Thanks for the query. Tablet Glynase MF contains Glibeclamide an earlier sulfonylurea and Glycomet GP contains Glimiperide. Both are different. Can not be just replaced one for another. You have to talk to your doctor about the dosage when ...
Who can provide more information about nateglinide?
Your pharmacist can provide more information about nateglinide.
What is nateglinide (Starlix)?
Nateglinide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. This medicine is not for treating type 1 diabetes.
What are the possible side effects of nateglinide (Starlix)?
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
What is the most important information I should know about nateglinide (Starlix)?
You should not use nateglinide if you have diabetic ketoacidosis (call your doctor for treatment).
What should I avoid while taking nateglinide (Starlix)?
Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.
How old do you have to be to take Nateglinide?
Nateglinide is not approved for use by anyone younger than 18 years old.
What is Multum's drug information?
Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
What to do if you overdose on natellinide?
If you think you or someone else may have overdosed on: Nateglinide (Starlix) , call your doctor or the Poison Control center. (800) 222-1222. If someone collapses or isn't breathing after taking Nateglinide (Starlix), call 911. 911.
How to treat hypoglycemia?
To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda). Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.
Can you breastfeed while taking Nateglinide?
Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby. You should not breastfeed while using this medicine. Nateglinide is not approved for use by anyone younger than 18 years old.
Can you take Nateglinide with diabetes?
This medicine is not for treating type 1 diabetes. Other diabetes medicines are sometimes used in combination with nateglinide if needed. Nateglinide may also be used for purposes not listed in this medication guide.
What is Starlix (nateglinide)?
Starlix (nateglinide) belongs to the meglitinide drug class that works by making the cells in your body release more insulin.
What are the side effects of Starlix (nateglinide)?
With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.
How much does Starlix (nateglinide) cost?
Starlix (nateglinide) is available as a generic medication and may be significantly cheaper compared to the brand version. Unless there is a specific reason you need the brand, the generic medication will be a better value. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price.
What is the purpose of Starlix?
Starlix (nateglinide) is an add-on medication to diet and exercise to control blood sugar in people with type 2 diabetes.
What is nateglinide used for?
Nateglinide is used to treat a type of diabetes mellitus (sugar diabetes) called type 2 diabetes. With this type of diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly. Using nateglinide alone, or with metformin or a thiazolidinedione (other types of oral antidiabetic medicines), ...
Is Nateglinide available with a prescription?
Nateglinide is available only with your doctor's prescription.
Does Nateglinide help with diabetes?
Their blood glucose is best controlled by insulin injections. Nateglinide does not help patients who have already been treated with other antidiabetic medicines for a long time.
Does Nateglinide help with antidiabetic medicine?
Nateglinide does not help patients who have already been treated with other antidiabetic medicines for a long time.
Medical uses
- Nateglinide is used alone or in combination with other medications to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood) in people whose diabetes cannot be controlled by diet and exercise alone. Nateglinide belongs to a class of drugs called meglitinides. N...
Treatment
- Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your h…
Usage
- Nateglinide comes as a tablet to take by mouth. It is usually taken three times daily. Take nateglinide any time from 30 minutes before a meal to just before the meal. If you skip a meal, you need to skip the dose of nateglinide. If you add a meal, add a dose of nateglinide. Your doctor may gradually increase your dose, depending on your response to nateglinide. Monitor your blo…
Preparation
- Before you start taking nateglinide, ask your doctor what to do if you forget to take a dose. Write these directions down so you can refer to them later. As a general rule, if you have just begun to eat a meal, take the missed dose as soon as you remember it. However, if you have finished eating, or if it is almost time for the next dose, skip the missed dose and continue your regular d…
Prevention
- Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resista…
Results
- Keep all appointments with your doctor and the laboratory. Your blood sugar and glycosylated hemoglobin (HbA1c) should be checked regularly to determine your response to nateglinide. Your doctor will also tell you how to check your response to this medication by measuring your blood or urine sugar levels at home. Follow these instructions carefully.