
Minute Ventilation in Health and Disease
Condition | Minute ventilation | N. of patients | Prevalence of CHV | Reference |
Normal breathing | 6 l/min | – | 0 % | Medical textbooks |
Heart disease | 15 (±4) l/min | 22 | 100% | Dimopoulou et al, 2001 |
Heart disease | 16 (±2) l/min | 11 | 100% | Johnson et al, 2000 |
Heart disease | 12 (±3) l/min | 132 | 100% | Fanfulla et al, 1998 |
What causes high minute ventilation?
- The minute volume has fallen below the lower alarm limit
- Obstruction
- Flow sensor is not calibrated or faulty
- Leakage or disconnection
- Device failure
What is the formula for minute ventilation?
Minute ventilation can double with light exercise, and it can even exceed 40 L/min with heavy exercise. The most commonly used minute ventilation equation is: VE in mL/min = Tidal volume (Vt) in mL x Respiratory rate (RR) in resp/min.
What is considered normal adult respiration per minute?
- Infants between 2 months to 1 year old: More than 50 breaths per minute.
- Children aged 1–12: More than 40 breaths per minute.
- Children over 12 years old: More than 20 breaths per minute.
What is normal breaths per minute in adult with COPD?
The normal respiratory rate for a healthy adult ranges from 12 to 18 breaths per minute. If you take more than 20 breaths per minute for at least a few minutes, you would be described as having tachypnea. Typically, when you have COPD, you may feel a sense of discomfort during episodes of tachypnea.

What is high minute ventilation?
Minute ventilation during moderate exercise may be between 40 and 60 litres per minute. Hyperventilation is the term for having a minute ventilation higher than physiologically appropriate. Hypoventilation describes a minute volume less than physiologically appropriate.
What is the normal ventilation rate?
The normal respiration rate for an adult at rest is 12 to 20 breaths per minute.
How do you calculate minute ventilation?
Minute ventilation = tidal volume x respiratory rate (normal is 4-6 L/min) Tidal volume = alveolar space + dead space.
What is normal respiratory minute volume?
5-8 liters per minuteA normal minute volume would be 5-8 liters per minute. or MV. "Alveolar ventilation" is a closely related quantity, consisting of the respiratory rate multiplied by the dead space subtracted from the tidal volume.
What is low minute ventilation?
Low Minute Ventilation (Ve): This alarm will sound when the amount of air taken in perminute drops below a set value. It will act similar to a low pressure alarm and usually indicates some kind of a leak or disconnect in the system. High pressure alarm: This will sound when the pressure in the circuit has increased.
Is 30 breaths a minute normal?
A normal breathing rate for an adult at rest is 8 to 16 breaths per minute. For an infant, a normal rate is up to 44 breaths per minute.
How do you calculate Vt?
*VT is the volume of air inspired/expired with each breath. (Also, VT= IC-IRV. VT= VC-(IRV+ERV), VT= TLC-(IRV+ERV+RV).
What is a normal tidal volume?
On average, adults breathe 7 milliliters (mL) per kilogram (kg) of ideal body weight. The average adult female has a Vt of around 400 mL, and the average adult male has a Vt of around 500 mL.
Determination of minute volume
Minute volume can either be measured directly or calculated from other known parameters.
Physiological significance of minute volume
Blood carbon dioxide (PaCO 2) levels generally vary inversely with minute volume. For example, a person with increased minute volume (e.g. due to hyperventilation) should demonstrate a lower blood carbon dioxide level. The healthy human body will alter minute volume in an attempt to maintain physiologic homeostasis.
Relationship to other physiological rates
Minute volume comprises the sum of alveolar ventilation and dead space ventilation. That is:

Overview
Physiological significance of minute volume
Blood carbon dioxide (PaCO2) levels generally vary inversely with minute volume. For example, a person with increased minute volume (e.g. due to hyperventilation) should demonstrate a lower blood carbon dioxide level. The healthy human body will alter minute volume in an attempt to maintain physiologic homeostasis. A normal minute volume while resting is about 5–8 liters per minute in humans. Minute volume generally decreases when at rest, and increases with exercise…
Determination of minute volume
Minute volume can either be measured directly or calculated from other known parameters.
Minute volume is the amount of gas inhaled or exhaled from a person's lungs in one minute. It can be measured by a Wright respirometer or other device capable of cumulatively measuring gas flow, such as mechanical ventilators.
If both tidal volume (VT) and respiratory rate (ƒ or RR) are known, minute volume can be calculate…
Relationship to other physiological rates
Minute volume comprises the sum of alveolar ventilation and dead space ventilation. That is:
where is alveolar ventilation, and represents dead space ventilation.
External links
• Overview at healthsystem.virginia.edu
• Nosek, Thomas M. "Section 4/4ch3/s4ch3_15". Essentials of Human Physiology. Archived from the original on 2016-03-24.
• What is minute ventilation