Precautions
The most common side effects of Reglan include:
- restlessness
- drowsiness
- tiredness
- lack of energy
What are some side effects of taking drug "Reglan"?
Reglan works best for acid reflux if taken 30 minutes before each meal and at bedtime. Patients using Reglan to treat acid reflux should not take more than the maximum recommended daily dosage of 60 mg. If taken intermittently, or only as symptoms occur, a single dose of Reglan up to 20 mg can be administered as the situation warrants.
When should I take Reglan?
Take note that the primary adverse effect of Reglan is tardive dyskinesia (disorder characterized by uncontrollable, repetitive movements). Some other medications that may interact with Reglan include: Antidepressants & Antipsychotics such as Abilify, Seroquel, and Zyprexa Antispasmodics (drugs that contain hyocyamine, scopolamine and atropine)
Does Reglan interact with other medications?
Your chances for getting tardive dyskinesia increase:
- the longer you take Reglan and the more Reglan you take. You should not take Reglan for more than 12 weeks.
- if you are older, especially if you are an older woman.
- if you have diabetes.
Should I take Reglan?
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What symptoms does Reglan treat?
Reglan (metoclopramide) is a dopamine antagonist that is used as an antiemetic (anti-vomiting) agent used to treat nausea, vomiting, loss of appetite, heartburn and early satiety (feeling of fullness). Reglan is available in generic form.
What is the most common side effect of Reglan?
Reglan (metoclopramide) is prescribed for gastrointestinal disorders. The most common side effects of the drug are relatively minor and include restlessness, drowsiness, fatigue and a general lack of energy.
How does Reglan make you feel?
You may feel very anxious and restless for a short time, and then become sleepy while you are receiving a dose of REGLAN. Tell your doctor or nurse right away if this happens. You may have more side effects the longer you take REGLAN and the more REGLAN you take.
Is Reglan good for stomach pain?
Reglan is used for 4 to 12 weeks to treat heartburn caused by gastroesophageal reflux in people who have used other medications without relief. Reglan is also used to treat gastroparesis (slow stomach emptying) in people with diabetes, which can cause heartburn and stomach discomfort after meals.
Why was Reglan taken off the market?
The incidence of TD in long-term Reglan users is cited to be as high as 20 percent in the literature. This led to the FDA requiring a black-box warning in 2009. The warning advises patients about the dangers of developing tardive dyskinesia after long-term use of Reglan and its generic counterparts.
What can I take instead of Reglan?
At present, the only available alternative to metoclopramide that has been extensively studied in critically ill patients is erythromycin, but both agents are commonly used as a combined strategy to improve gastric emptying and improve patient outcomes [11].
How quickly does Reglan work?
Metoclopramide (Reglan) typically begins to work in 30 minutes, so it's best when you time it with your meals. Taking metoclopramide (Reglan) at bedtime will also help relieve any worsening symptoms, since the muscle movements in your gut normally slows down at night.
Is Reglan used for anxiety?
Compazine (prochlorperazine) and Reglan (metoclopramide) are used to control severe nausea and vomiting. Compazine is also used to treat psychotic disorders such as schizophrenia and to treat anxiety. Reglan is also used to treat loss of appetite, heartburn, and early satiety (feeling of fullness).
Are Zofran and Reglan the same?
Zofran and Reglan belong to different antiemetic drug classes. Zofran is a selective 5-HT3 receptor antagonist and Reglan is a dopamine antagonist.
When should I take Reglan?
Adults—At first, 10 to 15 milligrams (mg) four times a day, taken 30 minutes before symptoms are likely to begin or before each meal and at bedtime, for 4 to 12 weeks. Your doctor may adjust your dose as needed. However, the dose is usually not more than 60 mg per day.
Can you get Reglan over the counter?
Metoclopramide is also used to treat heartburn for patients with gastroesophageal reflux disease (GERD). GERD is esophageal irritation from the backward flow of gastric acid into the esophagus. This medicine is available only with your doctor's prescription.
Is Reglan good for acid reflux?
REGLAN relieves daytime heartburn and heartburn after meals. It also helps ulcers in the esophagus to heal. to relieve symptoms of slow stomach emptying in people with diabetes. REGLAN helps treat symptoms such as nausea, vomiting, heartburn, feeling full long after a meal, and loss of appetite.
What are the serious side effects of metoclopramide?
Serious side effectsDepression and suicide. ... Neuroleptic malignant syndrome (nervous system disorder). ... Tardive dyskinesia, a movement disorder that can be permanent. ... Parkinsonism (symptoms similar to those caused by Parkinson's disease). ... Allergic reaction. ... Hyperprolactinemia (increased levels of the hormone prolactin).More items...
How long do Reglan side effects last?
These side effects may take two to three months to subside following discontinuation. Adults aged less than 30 are more at risk. Metoclopramide use has been associated with the development of tardive dyskinesia (TD) (a nerve disorder characterized by involuntary movements of the face and jaws).
Can you stop Reglan cold turkey?
If you suddenly stop using this medication, you may have withdrawal symptoms (such as dizziness, nervousness, headaches). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used metoclopramide for a long time or in high doses.
What are the adverse effects of metoclopramide?
What side effects can this medication cause?drowsiness.excessive tiredness.weakness.headache.dizziness.diarrhea.nausea.vomiting.More items...•
What is diabetic gastroparesis?
Gastroparesis is a condition where muscles in your gut move slower than normal, causing food to stay in your stomach longer. This can lead to sympt...
Can I still take metoclopramide (Reglan) for gastroparesis if I don't have diabetes?
Currently, metoclopramide (Reglan) is only FDA-approved for diabetic gastroparesis. Even though most studies with this medication have focused on t...
Why is metoclopramide (Reglan) not a first-choice option to treat GERD?
Metoclopramide (Reglan) is not the first-choice medication for GERD because it might cause some permanent and serious side effects, such as uncontr...
Can I use metoclopramide (Reglan) for nausea and vomiting?
Metoclopramide (Reglan) has been prescribed off-label (not FDA-approved) by providers for treating morning sickness during pregnancy and nausea and...
What other forms of metoclopramide (Reglan) can I take if I have a hard time swallowing tablets?
Metoclopramide (Reglan) is also available as a fast-melting tablet, liquid, nasal spray, and injection. Metoclopramide (Reglan) fast-melting tablet...
How long does metoclopramide last?
This medication is used to treat certain conditions of the stomach and intestines. Metoclopramide is used as a short-term treatment (4 to 12 weeks) for persistent heartburn when the usual medicines do not work well enough. It is used mostly for heartburn that occurs after a meal or during the daytime.
How to report metoclopramide side effects in Canada?
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Precautions. Before taking metoclopramide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
How long can you take metoclopramide?
Metoclopramide comes in different forms (such as tablets, solution, injection). Do not use metoclopramide products for longer than 12 weeks. Talk to your doctor about the risks and benefits of this medication.
Can metoclopramide be lowered?
To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used metoclopramide for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal. Tell your doctor if your condition persists or worsens. Side Effects.
How should I take Reglan?
Take Reglan exactly as your healthcare provider tells you. Do not change your dose unless your healthcare provider tells you to.
What are the possible side effects of Reglan?
Tardive dyskinesia (abnormal muscle movements). See “ What is the most important information I need to know about Reglan? ”
What should I tell my healthcare provider before taking Reglan?
Before taking Reglan, tell your healthcare provider about all of your medical conditions, including if you:
What should I avoid while taking Reglan?
Do not drink alcohol while taking Reglan. Alcohol may make some side effects of Reglan worse, such as feeling sleepy.
What is the name of the medicine that contains metoclopramide?
another medicine that contains metoclopramide, such as Reglan injection or metoclopramide oral solution
How to keep Reglan in bottle?
Keep Reglan in the bottle it comes in and away from light. Keep the bottle closed tightly.
What is the condition called when you have reglan?
Neuroleptic Malignant Syndrome (N MS). NMS is a very rare but very serious condition that can happen with Reglan. NMS can cause death and must be treated in a hospital. Symptoms of NMS include: high fever, stiff muscles, problems thinking, very fast or uneven heartbeat, and increased sweating.
What is Reglan used for?
Reglan is a prescription medicine used to treat symptoms of gastroesophageal reflux disease (GERD), nausea and vomiting caused by chemotherapy, diabetic gastroparesis and during radiology of the upper gastrointestinal tract. Reglan may be used alone or with other medications.
What are the side effects of Reglan?
What are the possible side effects of Reglan? Reglan may cause serious side effects including: tremors or shaking in your arms or legs, confusion, depression, thoughts of suicide or hurting yourself, slow or jerky muscle movements in your face, convulsions ( seizure ), anxiety,
How much metoclopramide is used for EPS?
Acute dystonic reactions, the most common type of EPS associated with metoclopramide, occur in approximately 0.2% of patients (1 in 500) treated with 30 to 40 mg of metoclopramide per day . Symptoms include involuntary movements of limbs, facial grimacing, torticollis, oculogyric crisis, rhythmic protrusion of tongue, bulbar type of speech, trismus, opisthotonus ( tetanus -like reactions), and, rarely, stridor and dyspnea possibly due to laryngospasm; ordinarily these symptoms are readily reversed by diphenhydramine (see WARNINGS ).
How long does reglan last?
reglan ® tablets are indicated as short-term (4 to 12 weeks) therapy for adults with symptomatic, documented gastroesophageal reflux who fail to respond to conventional therapy. The principal effect of metoclopramide is on symptoms of postprandial and daytime heartburn with less observed effect on nocturnal symptoms.
How much reglan should I take?
Administer from 10 mg to 15 mg reglan ® (metoclopramide hydrochloride, USP) orally up to q.i.d. 30 minutes before each meal and at bedtime, depending upon symptoms being treated and clinical response (see CLINICAL PHARMACOLOGY and INDICATIONS AND USAGE ). If symptoms occur only intermittently or at specific times of the day, use of metoclopramide in single doses up to 20 mg prior to the provoking situation may be preferred rather than continuous treatment. Occasionally, patients (such as elderly patients) who are more sensitive to the therapeutic or adverse effects of metoclopramide will require only 5 mg per dose.
How long does metoclopramide last?
The onset of pharmacological action of metoclopramide is 1 to 3 minutes following an intravenous dose, 10 to 15 minutes following intramuscular administration, and 30 to 60 minutes following an oral dose; pharmacological effects persist for 1 to 2 hours.
How to report side effects of prescription drugs?
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
What is metoclopramide (Reglan)?
Metoclopramide (Reglan) mainly works as a dopamine antagonist (blocks dopamine). Dopamine is a chemical made by your brain that affects many parts of your body, including the digestive tract.
What are the risks and warnings for metoclopramide (Reglan)?
Metoclopramide (Reglan) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options
How long can you take metoclopramide?
Prolonged treatment with metoclopramide (greater than 12 weeks) should be avoided in all but rare cases where therapeutic benefit outweighs the risks . Save up to 50% on Metoclopramide. Find big savings at pharmacies near you with GoodRx discount coupons.
What is the generic name for Metoclopramide?
Metoclopramide. Generic Reglan, Metozolv. METOCLOPRAMIDE is used to treat the symptoms of gastroesophageal reflux disease ( GERD) like heartburn. It is also used to treat people with slow emptying of the stomach and intestinal tract.
Does Reglan cause tardive dyskinesia?
Metoclopramide (Reglan) can cause tardive dyskinesia, a side effect in which there is uncontrolled muscle movements in the tongue, face, mouth, lips, hands, arms, legs, and feet. Your risk of this side effect is higher if you take other medications that might also cause tardive dyskinesia, such as prochlorperazine, haloperidol (Haldol), fluoxetine (Prozac), or carbidopa/levodopa (Sinemet). Avoid using metoclopramide (Reglan) if you are taking these medications. Talk to your provider right away if you notice any unusual movements you can't control because they can become permanent.
Is Reglan a first choice medication?
Metoclopramide (Reglan) is not the first-choice medication for GERD because it might cause some permanent and serious side effects, such as uncontrolled muscle movements. It also interacts with many medications, such as antipsychotics and antidepressants. Other medications that treat GERD, such as calcium carbonate (TUMS), famotidine (Pepcid AC), and omeprazole (Prilosec) have less risks for serious side effects compared with metoclopramide (Reglan). If you've already tried other medications for GERD and they didn't work well for you, talk to your healthcare provider to see if metoclopramide (Reglan) is a good option for you.
Can you drink alcohol while taking Reglan?
Avoid driving or performing any activity that requires a lot of attention until you know how this medication affects you. Do not drink alcohol while taking this medication, as it can make this side effect worse.
What is Reglan medicine?
Reglan (Metoclopramide) is a medicine that increases the movements or contractions of the stomach and intestines. When given by injection, it is used to help diagnose certain problems of the stomach and/or intestines.
What to tell your doctor about metoclopramide?
The following should be discussed with your doctor. Allergies: Tell your doctor if you have ever had any unusual or allergic reaction to metoclopramide, procaine, or procainamide. Also tell your healthcare professional if you are allergic to any other substances, such as foods, preservatives, or dyes. Breastfeeding: Metoclopramide passes ...
What to know before taking metoclopramide?
Before Using This Medicine 1 Allergies: Tell your doctor if you have ever had any unusual or allergic reaction to metoclopramide, procaine, or procainamide. Also tell your healthcare professional if you are allergic to any other substances, such as foods, preservatives, or dyes. 2 Breastfeeding: Metoclopramide passes into the breast milk and may cause unwanted effects in nursing babies. 3 Children: Muscle spasms, especially of jaw, neck, and back, and tic-like (jerky) movements of head and face may be especially likely to occur in children. Premature and full-term infants may develop blood problems if given high doses of metoclopramide. 4 Older adults: Shuffling walk and trembling and shaking of hands may be especially likely to occur in elderly patients after they have taken metoclopramide over a long time. 5 Other medicines: When you are taking metoclopramide, it is especially important that your healthcare professional know if you are taking central nervous system (CNS) depressants (medicine that causes drowsiness). Using these medications with metoclopramide may cause severe drowsiness.
Why is a syringe used for stomach pain?
When given by injection, it is used to help diagnose certain problems of the stomach and/or intestines. It is also used by injection to prevent the nausea and vomiting that may occur after treatment with anticancer medicines. Hero Images / Getty Images.
What are the medical problems associated with metoclopramide?
Make sure you tell your doctor if you have any other medical problems, especially: Abdominal or stomach bleeding. Asthma. High blood pressure. Intestinal blockage. Mental depression.
What is Reglan used for?
What Is Reglan? Reglan (metoclopramide) is a dopamine antagonist that is used as an antiemetic (anti- vomiting) agent used to treat nausea, vomiting, loss of appetite, heartburn and early satiety (feeling of fullness). Reglan is available in generic form.
What are the side effects of Reglan?
urinating more than usual. Tell your doctor if you experience serious side effects of Reglan including: tardive dyskinesia ( unusual muscle movements), muscle stiffness, depression, agitation, and. difficulty breathing.
How much metoclopramide is used for EPS?
Acute dystonic reactions, the most common type of EPS associated with metoclopramide, occur in approximately 0.2% of patients (1 in 500) treated with 30 to 40 mg of metoclopramide per day . Symptoms include involuntary movements of limbs, facial grimacing, torticollis, oculogyric crisis, rhythmic protrusion of tongue, bulbar type of speech, trismus, opisthotonus ( tetanus -like reactions), and, rarely, stridor and dyspnea possibly due to laryngospasm; ordinarily these symptoms are readily reversed by diphenhydramine (see WARNINGS ).
How to know if you are allergic to metoclopramide?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop taking metoclopramide and call your doctor at once if you have any of these SIGNS OF A SERIOUS MOVEMENT DISORDER, which may occur within the first 2 days of treatment:
What is motor restlessness?
Motor restlessness ( akathisia) may consist of feelings of anxiety, agitation, jitteriness, and insomnia, as well as inability to sit still, pacing, foot tapping. These symptoms may disappear spontaneously or respond to a reduction in dosage.
Can you take Reglan while pregnant?
Reglan During Pregnancy and Breastfeeding. Pregnant females should consult with their OB - GYN physicians before taking this medicine. Caution should be exercised when Reglan is administered to a nursing mother. Consult your doctor before breastfeeding.
Does metoclopramide cause jaundice?
Rarely, cases of hepatotoxicity, characterized by such findings as jaundice and altered liver function tests, when metoclopramide was administered with other drugs with known hepatotoxic potential.
Where is metoclopramide given?
A metoclopramide injection is given into a muscle or as an infusion into a vein. A healthcare provider will give the injection, usually during surgery, chemotherapy, or a medical procedure.
What is metoclopramide?
Metoclopramide increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines.
What other drugs will affect metoclopramide?
Using metoclopramide with other drugs that make you drowsy can worsen this effect. Ask your doctor before you take opioid pain medication, a sleeping pill, a muscle relaxer, or medicine for anxiety, depression, or seizures.
How long can you take metoclopramide?
NEVER USE METOCLOPRAMIDE IN LARGER AMOUNTS THAN RECOMMENDED, OR FOR LONGER THAN 12 WEEKS. High doses or long-term use can cause a serious movement disorder that may not be reversible. The longer you use metoclopramide, the more likely you are to develop this movement disorder. The risk of this side effect is higher in diabetics and older adults (especially women).
What happens if you are allergic to metoclopramide?
Get emergency medical help if you have signs of an allergic reaction to metoclopramide: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Can metoclopramide be used for longer than 12 weeks?
NEVER USE METOCLOPRAMIDE IN LARGER AMOUNTS THAN RECOMMENDED, OR FOR LONGER THAN 12 WEEKS. High doses or long-term use of metoclopramide can cause a serious movement disorder that may not be reversible. The longer you use metoclopramide, the more likely you are to develop this movement disorder. The risk of this side effect is higher in diabetics and older adults (especially women).
Can you take metoclopramide if you are allergic to it?
You should not use metoclopramide if you are allergic to it, or if you have:
