Salicylamide (o-hydroxybenzamide or amide of salicyl) is a non-prescription drug with analgesic and antipyretic
Antipyretic
Antipyretics are substances that reduce fever. Antipyretics cause the hypothalamus to override a prostaglandin-induced increase in temperature. The body then works to lower the temperature, which results in a reduction in fever.
What is salicylamide?
Salicylamide is the simplest member of the class of salicylamides derived from salicylic acid. It has a role as a non-narcotic analgesic and an antirheumatic drug. It is a member of salicylamides and a member of phenols. Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl.
What are the different doses of salicylamide?
Salicylamide is available in the following doses: Acetaminophen-salicylamide 250 Mg-600 Mg Oral Tablet Acetaminophen/aspirin/caffeine/salicylamide 115 Mg-210 Mg-16 Mg-65 Mg Oral Tablet Acetaminophen/aspirin/caffeine/salicylamide 250 Mg-500 Mg-32.5 Mg-150 Mg Oral Tablet Acetaminophen/cpm/phenylephrine/salicylamide 150 Mg-2 Mg-5 Mg-250 Mg Oral Tablet
Is salicylamide sensitive to aspirin?
PT ALLERGIC TO ASPIRIN HAVE BEEN REPORTED NOT TO BE SENSITIVE TO SALICYLAMIDE. SALICYLIC ACID, SALICYLAMIDE, & ACETAMINOPHEN USUALLY DO NOT SHOW CROSS SENSITIVITY /TO OTHER PROSTAGLANDIN INHIBITORS AS DOES ASPIRIN/ IN...GROUP OF PT. Salicylamide is used in the treatment of minor aches and pains.
What is the effect of salicylamide on pindolol?
Salicylamide may decrease the antihypertensive activities of Pindolol. Salicylamide may decrease the excretion rate of Piperacillin which could result in a higher serum level. Salicylamide may decrease the excretion rate of Piracetam which could result in a higher serum level.
Is Salicylamide anti-inflammatory?
Salicylamide, a non-steroidal anti-inflammatory drug (NSAID), is used as an analgesic and antipyretic agent. We have previously shown that several NSAIDs have anti-melanogenic properties in B16F1 melanoma cells.
What is Salicylamide found in?
It has a role as a non-narcotic analgesic and an antirheumatic drug. It is a member of salicylamides and a member of phenols. Salicylamide is a natural product found in Streptomyces rimosus and Streptomyces spectabilis with data available.
Is Salicylamide in Excedrin?
Excedrin Migraine is identical to regular Extra Strength Excedrin. The combination of Acetaminophen/ Aspirin/ Caffeine/ Salicylamide is totally successful in limiting the effects of my migraines.
Is Salicylamide an irritant?
The substance is toxic to lungs, mucous membranes. Repeated or prolonged exposure to the substance can produce target organs damage. Repeated or prolonged inhalation of dust may lead to chronic respiratory irritation.
Is salicylamide more polar than acetaminophen?
Acetaminophen has a phenol and amide function group, but caffeine has multiple amide functional groups; therefore, acetaminophen is more polar than aspirin and less polar than caffeine.
Does BC powder have salicylamide?
BC powder (I) is a commercially available analgesic containing the active ingredients aspirin and salicylamide.
Why is Excedrin not made anymore?
They are being discontinued due to quality and assurance measures. GSK recently discovered inconsistencies in how products are transferred and weighed.
Why was Excedrin discontinued?
Why is there a shortage of Excedrin®? In their official statement, GlaxoSmithKline said they've halted production because of “inconsistencies in how we transfer and weigh ingredients.” There isn't a nationwide shortage yet, but drugstores won't be able to restock once they run out of their current supply.
Why did Excedrin stop production?
The company ceased nationwide production and distribution of its Excedrin Extra Strength and Excedrin Migraine products because of "inconsistencies in how we transfer and weigh ingredients," a GSK spokesperson told told ABC Syracuse affiliate WSYR.
Is salicylamide an Nsaid?
Salicylamide, a non-steroidal anti-inflammatory drug (NSAID), is used as an analgesic and antipyretic agent. We have previously shown that several NSAIDs have anti-melanogenic properties in B16F1 melanoma cells.
Does salicylamide have teratogenic effects?
It has been shown that the non-narcotic analgesic salicylamide is teratogenic for rats. When this drug is administered to rats during gestation, sulfate incorporation into the fetal skeleton is reduced.
Is salicylamide soluble in water?
It is used as an analgesic and as an antipyretic. Soluble in water (2.06 mg/ml at 25°C), chloroform, dimethyl sulfoxide, alcohol, and methanol (100 mg/ml).
Is salicylamide solubility in water?
Soluble in water (2.06 mg/ml at 25°C), chloroform, dimethyl sulfoxide, alcohol, and methanol (100 mg/ml). Keep container tightly sealed.
Is salicylamide a liquid?
Salicylamide is a white or light pink crystals or powder.
Is salicylamide an NSAID?
Salicylamide, a non-steroidal anti-inflammatory drug (NSAID), is used as an analgesic and antipyretic agent. We have previously shown that several NSAIDs have anti-melanogenic properties in B16F1 melanoma cells.
What is c13h18o2 used for?
Ibuprofen is a commonly used nonsteroidal antiinflammatory (NSAID) drug which is available both by prescription and over-the-counter. Ibuprofen is considered to be among the safest NSAIDs and is generally well tolerated but can, nevertheless, rarely cause clinically apparent and serious acute liver injury.
What is salicylamide used for?
Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies. 2-hydroxybenzamide appears as odorless white or slightly pink crystals. Bitter taste, leaves a sensation of warmth on the tongue. pH (saturated aqueous solution at 82°F) about 5.
What is the koc of salicylamide?
The Koc of salicylamide is estimated as approximately 118 (SRC), using an experimental log Kow of 1.28 (1) and a regression-derived equation (2,SRC). According to a recommended classification scheme (3), this estimated Koc value suggests that salicylamide has high mobility in soil (SRC).
What is the rate constant for the vapor phase reaction of salicylamide with photochemically produced hydroxyl?
The rate constant for the vapor-phase reaction of salicylamide with photochemically produced hydroxyl radicals has been estimated as 3.25X10-11 cu cm/molecule-sec at 25 °C (SRC) using a structure estimation method (1,SRC). This corresponds to an atmospheric half-life of about 12 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm (1,SRC). The reaction of phenols with nitrate radicals may also be important (2).
How long does salicylamide react with hydroxyl radicals?
Vapor-phase salicylamide is degraded in the atmosphere by reaction with photochemically produced hydroxyl radicals (SRC); the half-life for this reaction in air is estimated to be about 12 hours (3,SRC). Particulate-phase salicylamide may be physically removed from the air by wet and dry deposition (SRC).
What is the Henry's law constant for salicylamide?
The Henry's Law constant for salicylamide is estimated as 2.9X10-10 atm-cu m/mole (SRC) using a fragment constant estimation method (1). This value indicates that salicylamide will be essentially nonvolatile from water surfaces (2,SRC). Salicylamide's low vapor pressure, 6.9X10-6 mm Hg (3,SRC) and low Henry's Law constant (1,SRC) indicate that volatilization from dry and moist soil will not occur (SRC).
What does 2-hydroxybenzamide taste like?
2-hydroxybenzamide appears as odorless white or slightly pink crystals. Bitter taste, leaves a sensation of warmth on the tongue. pH (saturated aqueous solution at 82°F) about 5. Sublimation begins at the melting point. (NTP, 1992)
Is salicylamide a sedative?
Salicylamide's production and use as an analgesic, antipyretic, antirheumatic, sedative, and for protection against mildew and fungus in a variety of soaps, salves, lotions, and oils may result in its release to the environment through various waste streams. If released to soil, salicylamide will have high mobility. Volatilization of salicylamide will not be important from moist or dry soil surfaces. Insufficient data are available to determine the rate or importance of biodegradation of salicylamide in soil or water but its structure would suggest rapid biodegradation. If released to water, salicylamide may not adsorb to suspended solids and sediment. Salicylamide will be essentially nonvolatile from water surfaces. An estimated BCF value of 5.5 (3,SRC) suggests that salicylamide will not bioconcentrate in aquatic organisms. If released to the atmosphere, salicylamide will exist in both the vapor and particulate phases. Although salicylamide has not been detected in the atmosphere, vapor-phase salicylamide is degraded in the atmosphere by reaction with photochemically produced hydroxyl radicals with an estimated half-life of about 12 hours. Particulate-phase salicylamide may be physically removed from the air by wet and dry deposition. The reaction of phenols with nitrate radicals may also be important. The general population may be exposed to salicylamide through ingestion of salicylamide containing pharmaceuticals and use of certain soaps and lotions. (SRC)
What is the name of the drug DB08797?
DB08797. Background. Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin.
Can hydrocortisone butyrate be combined with salicylamide?
The risk or severity of gastrointestinal irritation can be increased when Hydrocortisone butyrate is combined with Salicylamide. Hydrocortisone cypionate. The risk or severity of gastrointestinal irritation can be increased when Hydrocortisone cypionate is combined with Salicylamide.
Does salicylamide increase the excretion rate of procaine?
Salicylamide may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level. The risk or severity of hypertension can be increased when Procaterol is combined with Salicylamide. The risk or severity of hypertension can be increased when Promazine is combined with Salicylamide.
Does salicylamide increase hemorrhage?
The risk or severity of bleeding and hemorrhage can be increased when Salicylamide is combined with Anistreplase. Antihemophilic factor (recombinant), PEGylated. Salicylamide may decrease the excretion rate of Antihemophilic factor (recombinant), PEGylated which could result in a higher serum level. Antipyrine.
Can fluticasone be combined with salicylamide?
The risk or severity of gastrointestinal irritation can be increased when Fluticasone propionate is combined with Salicylamide. Fluvoxamine. The risk or severity of gastrointestinal bleeding can be increased when Salicylamide is combined with Fluvoxamine.
Can salicylamide and amitriptyline be combined?
Amitriptylinoxide. The risk or severity of gastrointestinal bleeding can be increased when Salicylamide is combined with Amitriptylinoxide.
Does colestipol affect salicylamide?
Colestipol. Colestipol can cause a decrease in the absorption of Salicylamide resulting in a reduced serum concentration and potentially a decrease in efficacy.
How is this medicine (Acetaminophen, Aspirin, Caffeine, and Salicylamide Tablets) best taken?
Use this medicine (acetaminophen, aspirin, caffeine, and salicylamide tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
What are some other side effects of Acetaminophen, Aspirin, Caffeine, and Salicylamide Tablets?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
