what is sceletium used for

Full Answer

What is Sceletium?

Sceletium is a plant from South Africa. It has a long history of use as a traditional medicine by tribes of South Africa.

What is Sceletium tincture Used for?

The San and Khoi people from South Africa are known to have used Sceletium to subdue their hunger and thirst in tincture form. Besides, it was also used to relieve pain and elevate their mood. Pastoralists and hunter-gatherers also used the plant for mood alteration during prehistoric times.

What is Sceletium tortuosum?

Sceletium tortuosum, also called Kanna, Kauwgoed, and Canna, is a plant commonly found in South Africa. Sceletium has powerful mood-enhancing properties, and it has been used for hundreds of years as a relaxant by the indigenous peoples of South Africa.

What is Sceletium Kanna?

Sceletium has powerful mood-enhancing properties, and it has been used for hundreds of years as a relaxant by the indigenous peoples of South Africa. Historically, Kanna was chewed, smoked, or snuffed for its benefits.

How quickly does Sceletium work?

There is preliminary clinical evidence that the extracts effect, described by the excited researcher as “experiential”, which can be felt two hours after oral ingestion (versus up to two to three weeks with some well-known pharmaceutical anti-depressive drugs).

Can Sceletium make you high?

It has a long history of use as a traditional medicine by native peoples of South Africa. Some people also use sceletium to get "high." People use sceletium for anxiety, depression, and many other conditions, but there is no good scientific evidence to support these uses.

What is Elev8 used for?

Overview. Elev8 assists in coping with stress, irritability, emotional strain, mood fluctuations and might support cognitive function in adults.

How does Zembrin make you feel?

The present indications for Zembrin, as a dietary supplement are to elevate mood, relieve stress and improve cognition (focus). Adjectives like “anti-stress, calmness, focused, serenity, motivated, energy, improves sleep” are often used to describe the experiential effects of Zembrin.

Is Sceletium tortuosum safe?

Zembrin has been found to be safe and well-tolerated at doses of 8 and 25 mg taken orally once a day in a randomized, double-blind, parallel-group, placebo-controlled clinical trial, supporting the ethnobotanical record of safe use of S. tortuosum (Nell et al, 2013).

How long does it take for kanna to work?

Oral Ingestion Kanna plant matter can be eaten by chewing over a long period time and then swallowing, or it can be made into a tea, which reportedly tastes like green tea, only worse. Duration: The effects can take as long as 90 minutes to come on, but the experience is also much longer and can last for 4–5 hours.

What are the effects of Kanna?

The plant is traditionally known for its ability to elevate mood, reduce stress, tension, anti-anxiety and its tranquilizing properties [10]. Furthermore, it is used for illnesses such as abdominal pains, toothache, and some people chew, smoke, or use it as tea or snuff mostly for pressure.

Does Zembrin affect sleep?

We observed that subjects taking Zembrin reported improvement in the subjective quality of their sleep on the HAM-D subscale. While none of the subjects had a history of insomnia, the data showed that Zembrin had a positive effect on onset of sleep, as compared with the placebo group.

Is Kanna and Zembrin the same?

One of the most interesting new product launches at Supply Side West last week was stress-buster Zembrin, the first patented, standardized and clinically studied extract of Sceletium tortuosum, a succulent plant known by the San people of South Africa as 'Kanna'.

What is serotonin syndrome?

Serotonin syndrome is a serious drug reaction. It is caused by medications that build up high levels of serotonin in the body. Serotonin is a chemical that the body produces naturally. It's needed for the nerve cells and brain to function.

What is a sceletium?

Sceletium is THE model anxiolytic (anti-anxiety agent). Millennia of traditional Kanna usage confirms this, as do the experiences of anyone today who has used Sceletium. Anxiety has multiple associated causes, but a central theme among them is a racing hyperactivity of the mind and a subsequent and consequential hyperactivity of the autonomic nervous system. Sceletium works directly, in an adpatogenic way, to mediate the “pace” of the mind, slowing a racing mind and bringing a calm centeredness to the being. It is unmistakable and anyone who suffers from anxiety readily attests to this.

What can we learn from the Sceletium-mediated state?

A key point here is that one actually learns from the Sceletium-mediated state that it is naturally possible to enjoy those kinds of social situations, and that one actually has the capacity to be at ease in them.

Is scleletium a SRA?

As Sceletium is both a Serotonin Releasing Agent (SRA) and Serotonin Re-Uptake Inhibitor (SRI) it greatly increases levels of active serotonin as well as melatonin, and is thus a first choice treatment for these disorders.

Does scleletium help with serotonin?

Sceletium greatly enhances serotonin function in the brain (more than any other herb known) and does so more effectively than L-Tryptophan, 5-HTP and Griffonia (without causing the drowsiness that is often associated with these serotonin precursors).

Is scletium good for alcoholism?

Alcoholism. Again, for similar reasons as in the Stopping Smoking and Drug Addiction sections above, Sceletium serves as a very good treatment for alcoholism as well as pre-alcoholic behaviours that would tend to lead to full-blown alcohol dependency.

Is mesembrenone a good memory stimulant?

Mesembrenone, a key component in Sceletium, is a known PDE4 Inhibitor. PDE4 Inhibitors are known to have strongly pro-cognitive (including long-term memory improving), wakefulness-promoting and anti-inflammatory effects. A high-mesembrenone strain or extract of Sceletium would thus be an effective component of a CILTEP-style Nootropic stack in place of luteolin (derived from artichoke extract).

That may elevate mood, increase focus and reduce the effects of modern-day living

TriSTILL™ is Botanical Resource Holdings’ flagship product containing Trimesemine™ – a Sceletium tortuosum active ingredient – beneficial in managing the maladies of our modern lifestyles.

PRECAUTIONS

In rare cases side effects such as a transient mild headache, abdominal discomfort or nausea may occur.

What is a scleletium?

Sceletium is a plant from South Africa. It has a long history of use as a traditional medicine by tribes of South Africa. It has been used to enhance mood, cause relaxation, and euphoria. Traditionally, the roots and leaves were fermented and then chewed. It has also been used as snuff, smoked, or made into a tea or tincture.

Is sceletium safe to take?

Keep in mind that natural products are not always necessarily safe and dos ages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

What is the use of S. tortuosum?

In traditional use, a plug of dried fermented S. tortuosum was chewed to release its constituents. Alternatively, a fresh leaf was applied directly to a tooth, or a drop of fresh leaf juice placed on the tongue. A decoction or infusion may also be prepared. South African Biodiversity Institute 2016

Which alkaloids are most active in S. tortuosum?

The mesembrine alkaloids are the most active of these subgroups. Jeffs 1981 Other alkaloids include mesembrone, mesembrenol, and turtuosamine. Gas chromatography–mass spectroscopy confirms that the unfermented preparation of S. tortuosum contains more alkaloids than the fermented one.

What is mesembrine hydrochloride?

Mesembrine hydrochloride is an inhibitor of phosphodiesterase type 4 (PDE4) at a half maximal inhibitory concentration of 29 mcM. The selective inhibition of the PDE4 family of enzymes affects cell signaling. Gericke 2008 The total synthesis of (±)-mesembrine has been reported.

What is the psychoactive compound in S. tortuosum?

The amount of active compounds in the plant appears to vary by season and locality. Mesembrine is the major psychoactive compound in S. tortuosum Nielsen 2004 and is a potent selective serotonin (5-HT) reuptake inhibitor (SSRI).

What is mesembrine in Shikanga?

Shikanga 2012. Mesembrine, a phenylethylamine alkaloid, was first extracted from S. tortuosum in 1898. Smith 1998 It is the major alkaloid found in S. tortuosum, occurring at levels of 0.3% in the leaves and 0.86% in the stems. The amount of active compounds in the plant appears to vary by season and locality.

What is tortuosum plant?

Botany. S. tortuosum is a perennial decumbent or climbing succulent plant indigenous to South Africa. Gericke 2008, Harvey 2011 It has white to pale yellow or pale pink sessile flowers, usually 20 to 30 mm in diameter and with 4 to 5 sepals.

Is S. tortuosum a SSRI?

S. tortuosum reportedly acts as an SSRI, a PDE4 inhibitor, an acetylcholinesterase inhibitor, a CB1 receptor blocker, and a cytochrome P17A1 inhibitor. It has been suggested that the plant's SSRI activity is secondary to its monoamine-releasing activity.

What is a scleletium?

Sceletium is a plant from South Africa. It has a long history of use as a traditional medicine by tribes of South Africa. It has been used to enhance mood, cause relaxation, and euphoria. Traditionally, the roots and leaves were fermented and then chewed. It has also been used as snuff, smoked, or made into a tea or tincture.

Is sceletium safe to take?

Keep in mind that natural products are not always necessarily safe and dos ages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

What is a scleletium?

Sceletium is a plant from South Africa. It has a long history of use as a traditional medicine by tribes of South Africa. It has been used to enhance mood, cause relaxation, and euphoria. Traditionally, the roots and leaves were fermented and then chewed. It has also been used as snuff, smoked, or made into a tea or tincture.

Is sceletium safe to take?

Keep in mind that natural products are not always necessarily safe and dos ages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Why do people use sceletium?

(2) 3. Anti-Anxiety. The most popular reason that people use Kanna is for its anti-anxiety and anti-stress properties.

Where is Sceletium found?

Written By. BeWellBuzz. Sceletium tortuosum, also called Kanna, Kauwgoed, and Canna, is a plant commonly found in South Africa. Sceletium has powerful mood-enhancing properties, and it has been used for hundreds of years as a relaxant by the indigenous peoples of South Africa.

What is the effect of scleletium on the brain?

Sceletium interacts with the brain’s dopamine and serotonin receptors, causing the release of these feel-good chemicals in the brain . For this reason, it has been used for hundreds of years and continues to be used for its antidepressant, anti-anxiety, anti-stress, and analgesic properties.

Is scletium good for smoking?

Smoking, Drug, and Alcohol Addiction. Sceletium is an excellent supplement for anyone looking to quit an addiction, such as smoking, drugs, or alcohol. Firstly, Kanna helps to reduce symptoms of withdrawal, which makes the process a lot more bearable.

Does scleletium help with anxiety?

During times of stress and anxiety, it can be difficult to let your creative juices flow. Sceletium can help to calm the mind and improve creativity, memory, and overall cognitive function.

Does sceletium cause insomnia?

Insomnia, usually due to taking a higher-than-recommended dose. A feeling of sedation, corrected by taking a smaller dose. All side effects reported were mild, and fortunately, no severe side effects have been reported from using sceletium.

Does Sceletium work?

Clinical anti-depressants, which are either SSRI (selective serotonin reuptake inhibitors) or SDRI (serotonin-dopamine reuptake Inhibitors), often take a while to start working and come with unwanted side effects. Sceletium works by causing the release of serotonin in the brain.

What is a fermented and dried preparation of Sceletium?

A fermented and dried preparation of Sceletium is known as Kanna or Kougoed. It means chewy things or something to chew, and it has been utilized as a very safe and advantageous inebriant since the prehistoric times. Kanna is chewed, prepared into tea and even smoked or snuffed sometimes.

What is the plant used for in the prehistoric period?

Besides, it was also used to relieve pain and elevate their mood. Pastoralists and hunter-gatherers also used the plant for mood alteration during prehistoric times. Jan van Riebeeck is known to have written the oldest account of its usage in the year 1662. A fermented and dried preparation of Sceletium is known as Kanna or Kougoed.

Does scleletium help with anxiety?

As an anxiolytic, Sceletium works really well. Sceletium slows down the hyperactivity of the mind and an abnormally active autonomic nervous system. If you suffer from problems like overthinking and anxiety, Sceletium is perfect for you. Anxiety is closely associated with social phobia.

Is scletium good for social phobia?

Anxiety is closely associated with social phobia. For people who find it tough to communicate, Sceletium can prove to be especially useful. The herb makes it all the more enjoyable for people to socialize. It proves to be a lot more than just a placebo.

Is scleletium a good healer?

All in all, it is a great healer. Sceletium stimulates the function of serotonin in the brain far better than L-Tryptophan, 5-Hydroxytryptophan, and Griffonia. What makes it superior to these agents is that it does not lead to drowsiness commonly experienced while using the precursors of serotonin.

Does Sceletium work?

They work by developing serotonin in the brain, but it leads to unwanted side effects. The pharmacological action of Sceletium is as a Serotonin Releasing Agent combined with a bit of SSRI activity.

What is Zembrin used for?

Zembrin (Sceletium Tortuosum) Benefits & Uses. Zembrin is a natural supplement that offers a boost to your everyday living, including bolstering your cognitive performance and mood.

Why is zembrin important?

When Zembrin is taken, it’s possible to protect the body’s immune cells and help slow the body’s inflammatory response.

What is Zembrin extract?

Zembrin is a one-of-a-kind supplement and is an extract from kanna, also called Sceletium Tortuosum. People have been using Sceletium for centuries, but Zembrin takes it a step further with: Zembrin is the first patented version of Sceletium Tortuosum.

Why do people take Zembrin?

Cognition benefits are often one of the key reasons that people take Zembrin. When taken, this product is shown to help a person’s cognition, which means the part of the brain that helps with:

How long does it take for zembrin to work?

Clinical studies are being performed using MRIs to determine how Zembrin impacts the brain. What the study found was that within a two-hour period , the ingredient, when given in 25mg doses, was able to reduce anxiety-related circuitry in the brain.

What is the selling point of Zembrin?

Zembrin’s biggest selling point is that this product has been highly tested. Consumers want to be sure that the products they purchase are high quality, and one of the best ways to do this is through rigorous testing. Clinical studies are being performed using MRIs to determine how Zembrin impacts the brain.

What is the South African government known for?

The South African government, which is known for its strict control over exports, granted the first Export and Bioprospecting permit to Zembrin. The permit took two years of negotiations and ensures that consumers are able to receive the best extract possible.

Clinical Overview

• Use
  S. tortuosum has been traditionally used to manage anxiety and depression, as well as to enhance mood, cognitive activity, and memory. However, clinical trials supporting these uses are lacking.
• Dosing
  Published clinical evidence is lacking to provide safe and effective dosing recommendations. S. tortuosum is available as a tincture, tablet, or capsule (in unit doses of 50 to 200 mg of the dried milled herbal material).

See more on drugs.com

Scientific Family

Botany

History

Chemistry

Uses and Pharmacology

Dosing

Interactions

Adverse Reactions

Toxicology