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what is small ldl p in blood test

by Kian Emmerich Published 3 years ago Updated 2 years ago
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Your Small LDL-P number is a measure of the number of small LDL particles in your blood. These particles are associated with an increased risk of heart disease; more of these small particles lead to greater risk. Please discuss various treatment options with your doctor.

Your Small LDL-P number is a measure of the number of small LDL particles in your blood. These particles are associated with an increased risk of heart disease; more of these small particles lead to greater risk. Your Small LDL particle score can vary widely, with a lower score being much better.

Full Answer

Is LDL of 117 bad?

The LDL, which is considered the “bad” cholesterol, should be less than 110, however, that number varies depending on risk factors. Borderline LDL levels range between 110 and 129 and anything greater than 130 is considered high. Know more about it here. Besides, what level of LDL is dangerous? LDL cholesterol levels should be less than 100 mg/dL.

What causes small dense LDL?

People at risk of developing small, dense LDL in the blood include:

  • Individuals who consume a high amount of carbohydrates in their diet 3 , especially refined sugars.
  • Those that consume trans fats in their diet.
  • Anyone who has uncontrolled diabetes.
  • Individuals who have been diagnosed with metabolic syndrome. 4 

What is the normal range for LDL?

The set guidelines for LDL cholesterol levels along with the interpretation range that help determine the heart risk of individuals is: Normal – >100 mg/dL Near-normal – 100-129 mg/dL Borderline High – 130-159 mg/dL High – 160-189 mg/dL Very High – 190 mg/dL Interpreting LDL Cholesterol Test Results Possible Cardiovascular Risks

What causes elevated LDL particle number?

What causes high LDL particle number? Obesity, diabetes, low HDL levels, infections, and inflammatory conditions are each associated with having an abundance of small, dense LDL particles. Also, certain conditions and lifestyle choices are linked with higher triglyceride and LDL levels and lower HDL levels. These include: obesity.

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How do I lower my small LDL-P?

Can I reduce my amount of small, dense LDLs?Eat a diet very rich in soluble fiber (BYOBB) – Beans, Yams, Oats, Barley, and Berries.Eat fewer refined carbohydrates.Eat much less saturated and trans fats and cholesterol.Exercise regularly, and.Lose excess weight.

What is the difference between LDL-P and small LDL-P?

Small LDLs correspondingly carry less cholesterol than large LDLs. In people with a large number of small-sized LDL particles in the blood, the LDL cholesterol value could be within the normal range despite a relatively high LDL particle number, or LDL-P.

What causes high small LDL?

There is a genetic pre-disposition to have small dense LDL. An atherogenic lifestyle involving minimal activity or exercise along with a typical American diet high in saturated fat is another cause. Insulin resistance or pre-diabetes is the last major cause of small dense LDL.

What is an LDL-P?

Low-density lipoprotein particles (LDL-P) are bi-products of fat transport that remain in circulation for an extended time. While in circulation, LDL-P can penetrate the artery wall and get stuck, forming a fatty plaque. These plaques can build over time and lead to blockages, resulting in heart attacks and strokes.

What does high small LDL mean?

Small dense LDL is the most atherogenic subtype of LDL, which means that it is more likely to leave fatty deposits in the blood. Having fatty deposits in the blood means that a person may be at higher risk of developing certain conditions, such as: heart disease. diabetes. obesity.

Do statins reduce small dense LDL?

One mechanism that prevents cardiovascular disease when statins are used is the reduction of total LDL particle concentration, including small, dense LDL and large, buoyant LDL.

Are small LDL particles bad?

The smallest and densest particles are high-density lipoproteins (HDL), also known as "good" cholesterol. They remove cholesterol from artery walls and return it to the liver for excretion. Low-density lipoprotein (LDL) particles are known as "bad" cholesterol.

What is considered high LDL-P?

For LDL-P, we categorized patients as optimal (<1,100), near optimal (1,101–1,399), borderline-high (1,400–1,799), high (1,800–2,100) or very high (>2,100).

Can you change your LDL particle size?

Alternate day fasting (ADF) with a low-fat (LF) diet increases low-density lipoprotein (LDL) particle size. Whether these beneficial effects can be reproduced by a high-fat (HF) ADF diet is unclear. This study compared an ADF-HF to an ADF-LF diet on plasma lipids, LDL size and high-density lipoprotein (HDL) size.

What is a normal range of LDL?

These are the adult ranges for LDL cholesterol: Optimal: Less than 100 mg/dL (This is the goal for people with diabetes or heart disease.) Near optimal: 100 to 129 mg/dL. Borderline high: 130 to 159 mg/dL.

Are there 2 types of LDL?

LDL consists of several subclasses of particles with different sizes and densities, including large buoyant (lb) and intermediate and small dense (sd) LDLs.

Can stress cause high LDL?

If high levels of stress are part of your daily life, you are at risk for high cholesterol, according to research. In a large study of more than 91,500 adults in different professions, job-related stress was linked to high cholesterol, including high LDL and low HDL cholesterol.

What should I do if my LDL is high?

AdvertisementEat heart-healthy foods. A few changes in your diet can reduce cholesterol and improve your heart health: ... Exercise on most days of the week and increase your physical activity. Exercise can improve cholesterol. ... Quit smoking. ... Lose weight. ... Drink alcohol only in moderation.

Why is my cholesterol high when I have a healthy diet?

Even if you eat right and exercise, you can still have high cholesterol if you have inherited a genetic form of high cholesterol from your parents called familial hypercholesterolemia. Even though it cannot be prevented, maintaining a healthy lifestyle can help keep the condition under control.

What foods cause high LDL?

Red meat, fried foods, and baked goods are notorious for raising levels of low-density lipoprotein (LDL) cholesterol, the sticky kind that builds up in artery walls.

What is a direct LDL test?

A direct LDL cholesterol test measures the actual amount of LDL cholesterol in a person’s blood. Some people with healthy LDL cholesterol levels can still be at risk of cardiovascular disease. For these individuals, a doctor may also use an LDL particle test (LDL-P). LDL-P tests can measure the number, size, and density ...

What is LDL cholesterol?

What to know about LDL blood tests. Low-density lipoprotein (LDL) cholesterol is a type of cholesterol in the blood. Blood tests can help determine a person’s LDL cholesterol levels. Having unhealthy levels of LDL cholesterol may increase a person’s risk of serious conditions, such as heart disease.

What is low density lipoprotein?

Low-density lipoprotein (LDL) cholesterol is a type of cholesterol in the blood. Blood tests can help determine a person’s LDL cholesterol levels. Having unhealthy levels of LDL cholesterol may increase a person’s risk of serious conditions, such as heart disease. Cholesterol moves around a person’s body via lipoproteins in their bloodstream.

How does cholesterol move?

Cholesterol moves around a person’s body via lipoproteins in their bloodstream. There are two types in the blood: LDL cholesterol and high-density lipoprotein (HDL) cholesterol. Some people may refer to LDL as “bad” cholesterol and HDL as “good” cholesterol. The body uses cholesterol to make cells, vitamins, and various hormones.

Why is LDL cholesterol important?

However, high levels of cholesterol can increase a person’s risk of heart disease. LDL blood tests can help a doctor monitor a person’s LDL cholesterol levels and treat any issues quickly.

What is the optimal LDL level?

The results of a cholesterol test will appear in milligrams per deciliter of blood (mg/dl). According to the CDC, the optimal level for LDL cholesterol is less than 100 mg/dl. Trusted Source.

How long do you have to fast for a LDL test?

Before the test. Before having an LDL blood test, a person may have to fast for 9–12 hours. Fasting means that a person cannot eat or drink anything but water during this time. However, a doctor may decide that a person does not need to fast before their LDL blood test.

What is the smallest LDL?

The subclasses of LDL cholesterol that are the smallest are called small dense LDL. However, this classification method may not always be the same among all studies.

What is the name of the test that shows the cholesterol level of a person?

A doctor can measure a person’s cholesterol level with a simple blood test. They call this a lipid panel or lipid profile because it shows the levels of each type of cholesterol.

Why is HDL cholesterol good?

Therefore, having a higher HDL level can correlate with lower LDL and VLDL levels. Some people call HDL cholesterol “good” because it reduces the amount of fat in a person’s blood.

What is the most atherogenic subtype of LDL?

Small dense LDL is the most atherogenic subtype of LDL, which means that it is more likely to leave fatty deposits in the blood. Having fatty deposits in the blood means that a person may be at higher risk of developing certain conditions, such as: heart disease. diabetes. obesity.

What is a small dense low density lipoprotein?

Small dense low-density lipoprotein (LDL) cholesterol is a type of potentially harmful cholesterol protein that can increase a person’s risk of heart disease if they have it in excess. Small dense LDL cholesterol is one of two proteins that carry cholesterol to and away from the body’s cells. The other type.

How low can you get LDL cholesterol?

under 40 mg per dl. Doctors have not established a firm limit on how low LDL cholesterol can get. However, experts suggest that men with an LDL level higher than 190 mg per dl receive cholesterol-lowering medications regardless of other risk factors. Learn more about healthy cholesterol levels here.

What are the best ways to reduce LDL?

LDL formation and high cholesterol include: avoiding trans fats and limiting foods high in saturated fat. eating high fiber foods, such as fruits and vegetables. maintaining or reaching a moderate body weight.

What tests can measure LDL?

However, there are tests that can measure small, dense LDL, which include: VAP cholesterol test. LDL gradient gel electrophoresis 2. NMR Lipoprofile test.

What is the difference between LDL and LDL?

The type of LDL in your body may influence your risk of having heart disease down the road. Small, dense L DL is a type of LDL cholesterol that is considered to be an emerging risk factor for cardiovascular disease. 1  It is smaller and heavier than typical LDL cholesterol and can increase your risk of developing atherosclerosis.

How to lower LDL cholesterol?

Ways you can lower your risk of small, dense LDL cholesterol formation include: If you have been diagnosed with diabetes, keep it under control by taking medication and following a healthy diet. Lose weight if you are obese. 2  This can be accomplished by following a healthy diet and moderate physical activity.

What are the risks of LDL?

People at risk of developing small, dense LDL in the blood include: 1 Individuals who consume a high amount of carbohydrates in their diet 3 , especially refined sugars. 2 Those that consume trans fats in their diet. 3 Anyone who has uncontrolled diabetes. 4 Individuals who have been diagnosed with metabolic syndrome. 4 

What are the factors that contribute to the formation of LDL?

People at risk of developing small, dense LDL in the blood include: Individuals who consume a high amount of carbohydrates in their diet 3 , especially refined sugars. Those that consume trans fats in their diet.

What medications can help reduce LDL?

These would include fibrates and statins.

Is high LDL cholesterol bad for you?

Having high LDL cholesterol, otherwise known as “bad” cholesterol, is not good for your heart health. However, more studies are now finding that it isn’t only the quantity of LDL circulating in your blood—it’s the quality, too. The type of LDL in your body may influence your risk of having heart disease down the road.

What is LDL-P cholesterol?

Standard cholesterol lab work measures LDL cholesterol (LDL-C). This is a measure of the amount of cholesterol contained within LDL particles. LDL-P measures the actual number of LDL particles. Research shows LDL-P to be a stronger predictor of heart disease than LDL-C.

What are the two types of LDL particles?

LDL particles come in two main sizes: Large, fluffy particles and small, dense particles.

How to reduce LDL particle size?

Add 20-30-minutes of exercise to your daily (or almost daily) routine for positive, long term improvements to LDL particle size. Discuss niacin supplementation with your doctor. Niacin has been used to effectively raise HDL cholesterol levels and research suggests niacin can lower LDL-P.

Why is LDL cholesterol important?

LDL cholesterol level is often used to determine if preventative treatment is needed, such as medication to lower levels in an effort to prevent heart disease .

How to increase LDL?

Positive changes to particle sizes from exercise are not permanent and will “go away” within two weeks of ceasing activity. Studies have found exercise duration to be a greater factor than exercise intensity. Add 20-30-minutes of exercise to your daily (or almost daily) routine for positive, long term improvements to LDL particle size.

Is LDL cholesterol a good determinant of heart disease?

However, research indicates LDL cholesterol alone is not necessarily a good determinant of risk. LDL particles vary in their content, size, and density. Not all LDL particles impact heart disease risk in the same way.

Does statin lower LDL?

It’s important to note statin medication does not decrease small, dense LDL levels. Just because you lower LDL-C to normal levels with statin treatment, your risk for heart disease may remain elevated if your LDL-P is above normal.

What Is LDL-P and Why Is It Important?

LDL-C is usually calculated using the Friedewald equation. However, this measure can underestimate LDL-C level as triglycerides increase. Direct LDL-C measurements are also available and better reveal individual issues, but are less often promoted or done due to slightly higher costs.

What is the LDL particle?

LDL is the lipoprotein particle that is mostly involved in atherosclerosis. LDL particles exist in different sizes. On the one hand there are the large, fluffy, cotton-ball like molecules, and on the other hand the small dense molecules. Many recent studies have looked into the importance of LDL-particle size.

What is the correlation between LDL and triglycerides?

Thus, the higher your triglycerides, the greater the number of small LDL parti cles. Conversely, the lower your triglycerides, the higher the number of large, fluffy LDL particles.

What are the two major lipoproteins that enable the transport of different fat molecules, including cholesterol?

HDL and LDL are two of five major lipoproteins that enable transport of different fat molecules, including cholesterol. The other lipoproteins are chylomicrons, IDL (intermediate density lipoprotein) and VLDL (very low-density lipoprotein, mainly triglycerides). LDL is the lipoprotein particle that is mostly involved in atherosclerosis.

What does LDL-C mean?

LDL-C reflects the total content or concentration of cholesterol within LDL-C particles in mg/dl or mmol/L. Since the amount of cholesterol in each particle may vary, measuring LDL-C does not necessarily reflect the actual number of particles. LDL-P (LDL particle number) measures the actual number of LDL particles (particle concentration, nmol/L).

Which is better, Apolipoprotein B or LDL-P?

Apolipoprotein B (apoB) and LDL-P, on the other hand, reflect the number of atherogenic particles, with no mention of cholesterol mass. Therefore apoB and LDL-P are believed to be better risk predictors than LDL-C.

Which type of fat is most often associated with increased risk of heart disease?

Cholesterol is the type of fat that is most often associated with increased risk of heart disease. High blood levels of low-density lipoprotein cholesterol (LDL-C) in particular are believed to increase risk.

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