what is the drug desyrel used for

Precautions

Trazodone, also know by brand names “Desyrel” and “Oleptro,” is an antidepressant medication that is used to treat major depressive disorders. Trazodone is a serotonin antagonist and reuptake inhibitor—not a narcotic. Yet, like narcotics, this drug has serious potential for abuse. What Is Trazodone?

Is Desyrel a narcotic?

Trazodone: Trazodone is the generic name for Desyrel and Oleptro. It was primarily developed as an antidepressant. It works by helping to increase the availability of serotonin in the brain. Serotonin is considered a natural mood stabilizer. It is also the chemical that helps with sleeping, eating, reducing depression, and regulating anxiety.

Is Desyrel the same as trazodone?

Trazodone stays in your body for one day to three days or less, in general for 42 hours. It does not mean after this period, it is out of your system, some traces of the drug can still remain in the body at lower levels. Trazodone can cause a number of side effects and are as follows:

How long does trazodone stay in your system?

The starting dose of trazodone for depression is 150 mg daily. It can then be increased to a max dose of 600 mg daily, which may be split across multiple doses during the day. Because trazodone is used at high doses in depression, it is important not to stop the drug cold turkey.

What is the maximum daily dose of trazodone?

Is Desyrel a sleeping pill?

There are numerous medications designed to address issues with insomnia. Two of the more popular medications are Ambien (zolpidem) and Desyrel or Oleptro (trazodone).

Is Desyrel used for anxiety?

Desyrel (trazodone) is used to treat all types of depression. It belongs to the SARI (serotonin antagonist and reuptake inhibitor) class. It is also used to treat anxiety and insomnia related to depression. Your doctor may use this medicine to treat other conditions.

How long does it take for trazodone to kick in for sleep?

Since it is a generic drug covered by most insurance plans, trazodone is lower in cost than other medications. Trazodone works quickly as a sleep aid, often taking only 30 minutes to feel the effects.

When should Desyrel be taken?

Take this medication by mouth after a meal or snack as directed by your doctor, usually once or twice daily. If drowsiness is a problem and you are taking 1 dose daily, take it at bedtime. If you are taking 2 doses each day, it may help to take 1 of the doses at bedtime. Follow your doctor's directions carefully.

How long does it take for 50mg of trazodone to kick in?

Trazodone can take 1 to 2 weeks to start to work, and it can be 4 to 6 weeks before you feel the full benefit. Give the medicine at least 6 weeks to work. Some people feel worse during the first few weeks of treatment before they begin to feel better.

What is the most likely side effect of trazodone?

The most common side effects of trazodone are drowsiness, nausea, dizziness, and dry mouth (Zhang, 2014). Trazodone is generally well tolerated and may be less likely than some other antidepressants to cause insomnia, sexual side effects, and anxiety (Shin, 2020).

Is it OK to take trazodone every night?

A key advantage of using trazodone to counter sleep issues is that it can be safely used for much longer than most common sleep aids. Normally, prescription sleeping pills are used for no more than two weeks. Trazodone can be safely used for longer than this.

What should you not take with trazodone?

Do not use trazodone with buspirone (Buspar®), fentanyl (Abstral®, Duragesic®), lithium (Eskalith®, Lithobid®), tryptophan, St. John's wort, or some pain or migraine medicines (eg, sumatriptan, tramadol, Frova®, Maxalt®, Relpax®, Zomig®).

How many hours does trazodone last?

Factors that Affect How Long Trazodone Stays in Your Body Trazodone has a half-life between five and 9 hours. This means it will take your body (on average) around seven hours to eliminate half of the drug. In a healthy adult, a single dosage of Trazodone can remain in the body for one to three days.

Is 50 mg of trazodone a lot?

The starting dose is usually 50 mg to 100 mg dose at bedtime. If needed, the dose can be increased to up to 200 mg at bedtime. Those with both depression and sleep problems may need a higher dose in some cases — up to 300 mg at bedtime.

What is best sleeping pill for elderly?

In the elderly, should prescription medication be necessary, the first-line treatment is nonbenzodiazepines (e.g., zolpidem, eszopiclone, zaleplon, and ramelteon) as they have been found to be safer and better tolerated than tricyclic antidepressants, antihistamines, and benzodiazepines.

Can trazodone cause memory loss?

Trazodone produced small but significant impairments of short-term memory, verbal learning, equilibrium, and arm muscle endurance across time points.

What kind of drug is Desyrel?

Desyrel is a prescription medicine used in adults to treat major depressive disorder (MDD). Desyrel belongs to a class of medicines known as SSRIs (or selective serotonin reuptake inhibitors).

What symptoms does trazodone treat?

Trazodone: a medicine to treat depression and anxiety - NHS.

Is Desyrel the same as trazodone?

In 1981, trazodone (the generic name of the pharmaceutical) was approved by the U.S. Food and Drug Administration (FDA) under the brand name Desyrel for use in treating major depressive disorder.

Is Desyrel a benzodiazepine?

Desyrel (trazodone) and Xanax belong to different drug classes. Desyrel (trazodone) is an antidepressant and Xanax is a benzodiazepine.

What Is Desyrel (Trazodone)?

Trazodone is an antidepressant medicine. It affects chemicals in the brain that may be unbalanced in people with depression.Trazodone is used to tr...

What Is The Most Important Information I Should Know About Desyrel (Trazodone)?

You should not use trazodone if you are allergic to it, or if you are being treated with methylene blue injection.Do not use trazodone if you have...

What Should I Discuss With My Healthcare Provider Before Taking Desyrel (Trazodone)?

You should not use trazodone if you are allergic to it, or if you are being treated with methylene blue injection.Do not use trazodone if you have...

How Should I Take Desyrel (Trazodone)?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take...

What Happens If I Miss A Dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...

What Happens If I Overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of trazodone can be fatal when it is taken with alcoho...

What Should I Avoid While Taking Desyrel (Trazodone)?

Do not drink alcohol. Trazodone can increase the effects of alcohol, which could be dangerous.Avoid getting up too fast from a sitting or lying pos...

Desyrel (Trazodone) Side Effects

Stop taking trazodone and call your doctor at once if you have a penis erection that is painful or lasts 6 hours or longer. This is a medical emerg...

What Other Drugs Will Affect Desyrel (Trazodone)?

Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking trazodone with a sleeping pill, na...

What is the purpose of antidepressants?

Antidepressant medications are used to treat a variety of conditions, including depression and other mental/ mood disorders. These medications can help prevent suicidal thoughts /attempts and provide other important benefits. However, studies have shown that a small number of people (especially people younger than 25) who take antidepressants ...

What medications cause drowsiness?

Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, marijuana ( cannabis ), antihistamines (such as cetirizine, diphenhydramine ), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and opioid pain relievers (such as codeine).

Are you currently using Desyrel Tablet?

This survey is being conducted by the WebMD marketing sciences department .

What is Desyrel used for?

What is Desyrel and how is it used? Desyrel is a prescription medicine used in adults to treat major depressive disorder (MDD). Desyrel belongs to a class of medicines known as SSRIs (or selective serotonin reuptake inhibitors).

How many patients were in the placebo controlled trial of SSRIs?

In pooled analyses of placebo-controlled trials of antidepressant drugs (SSRIs and other antidepressant classes) that included approximately 77,000 adult patients and over 4,400 pediatric patients, the incidence of suicidal thoughts and behaviors in pediatric and young adult patients was greater in antidepressant-treated patients than in placebo-treated patients. The drug-placebo differences in the number of cases of suicidal thoughts and behaviors per 1000 patients treated are provided in Table 1.

Can you increase a DESYREL dose?

Consider increasing DESYREL dose based on therapeutic response when DESYREL is coadministered with a strong CYP3A4 inducer [see DRUG INTERACTIONS ].

How many mg of Desyrel is in a tablet?

Desyrel is supplied for oral administration in 50 mg tablet.

What are the symptoms of antidepressants?

The following symptoms, anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia (psychomotor restlessness), hypomania, and mania, have been reported in adult and pediatric patients being treated with antidepressants for major depressive disorder as well as for other indications, both psychiatric and nonpsychiatric. Although a causal link between the emergence of such symptoms and either the worsening of depression and/or the emergence of suicidal impulses has not been established, there is concern that such symptoms may represent precursors to emerging suicidality.

Can Desyrel cause death?

Death from overdose has occurred in patients ingesting Desyrel (trazodone hydrochloride) and other drugs concurrently (namely, alcohol; alcohol + chloral hydrate + diazepam; amobarbital; chlordiazepoxide; or meprobamate).

Is Desyrel a tricyclic?

Desyrel ( trazodone hydrochloride) is an antidepressant chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. Trazodone hydrochloride is a triazolopyridine derivative designated as 2- [3- [4- (3-chlorophenyl)-1-piperazinyl]propyl]-1,2,4-triazolo [4,3-a]pyridin-3 (2 H )-one hydrochloride. It is a white, odorless, crystalline powder which is freely soluble in water. Its molecular weight is 408.3. The empirical formula is C 19 H 22 ClN 5 O • HCl and the structural formula is represented as follows:

Is Desyrel safe for children?

Patients who are started on therapy should be observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Desyrel is not approved for use in pediatric patients. (See WARNINGS and PRECAUTIONS: Pediatric Use ).

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How does a syringe work?

One of its actions is to regulate the neurotransmitter serotonin, which helps brain cells communicate with each other and influences many activities such as sleep , thoughts, mood, appetite, and behavior.

What is off label prescribing?

The FDA approves medications to treat specific conditions based on clinical trials. When doctors prescribe the medicine for conditions other than what was approved by the FDA , it is known as off-label prescribing. Off-label use of a medication is a widespread practice. Twenty percent of medications are prescribed off-label.

What is the most commonly prescribed antidepressant?

The most commonly prescribed antidepressants are reuptake inhibitors. Reuptake, as described by WebMD, is "the process in which neurotransmitters are naturally reabsorbed back into nerve cells in the brain after they are released to send messages between nerve cells.".

Why is antidepressant not widely used?

Due to negative side effects associated with the drug early on—including dizziness, fainting, irregular heartbeat (and in rare cases, priapism in men) —the antidepressant wasn’t widely favored in the medical community. Eventually, however, internists and clinicians recognized potential benefits of the drug, particularly when administered ...

Desyrel Dosage and Administration

Dosage Forms and Strengths

Contraindications

Warnings and Precautions

Adverse Reactions

Use in Specific Populations

Drug Abuse and Dependence

Overdosage

Desyrel Description

Desyrel - Clinical Pharmacology