Precautions
Gemfibrozil is used together with diet to treat very high cholesterol and triglyceride levels in people with pancreatitis. Gemfibrozil is also used to lower the risk of stroke, heart attack, or other heart complications in certain people with high cholesterol and triglycerides who have not been helped by other treatment methods.
How is gemfibrozil used to treat pancreatitis?
Gemfibrozil is used along with a proper diet to help lower fats ( triglycerides) and raise "good" cholesterol ( HDL) in the blood. It may also help to lower "bad" cholesterol ( LDL ). Gemfibrozil belongs to a group of drugs known as "fibrates." It works by decreasing the amount of fat produced by the liver.
How does gemfibrozil lower cholesterol?
Gemfibrozil belongs to a class of drugs called fibric acid derivatives. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Gemfibrozil works by changing the amount of cholesterol and other fats (lipids) in your body.
What class of drug is gemfibrozil?
Gemfibrozil (Lopid) is a fibrate. It works by helping to break down fats in the blood. This leads to the lowering of triglycerides (fats) and "bad" cholesterol (LDL) while increasing "good" cholesterol (HDL) in the body. What is gemfibrozil (Lopid) used for?
How does gemfibrozil (Lopid) work?
See more
What are the side effects of the drug gemfibrozil?
Common Side effects of Gemfibrozil include:Indigestion/heartburn.Stomach/abdominal pain.Atrial fibrillation.Diarrhea.Fatigue.Nausea.Vomiting.Eczema.More items...
Will gemfibrozil help you lose weight?
Some people who take gemfibrozil (Lopid) might experience weight loss, though this is not a common effect of the medication. Remember that it is best to maintain a healthy diet and lifestyle in order to lose weight, and to get the best effect from taking gemfibrozil (Lopid).
Is gemfibrozil the same as Lipitor?
Are Lopid and Lipitor the Same Thing? Lopid (gemfibrozil) and Lipitor (atorvastatin) are used to lower cholesterol levels. Lopid is also used to treat very high cholesterol and triglyceride levels in people with pancreatitis. Lipitor is also used to elevate HDL ("good") cholesterol.
Is gemfibrozil hard on the liver?
Gemfibrozil therapy is associated with mild and transient serum aminotransferase elevations and with rare instances of acute liver injury.
Does gemfibrozil make you tired?
dizziness, drowsiness; blurred vision; muscle or joint pain; or. loss of interest in sex, impotence.
What happens when you stop taking gemfibrozil?
Do not stop taking this medicine without first checking with your doctor. When you stop taking this medicine, your blood cholesterol levels may increase again. Your doctor may want you to follow a special diet to help prevent this from happening.
Who should not take gemfibrozil?
a patient who is producing milk and breastfeeding. a progressive liver disease called primary biliary cholangitis. chronic kidney disease stage 4 (severe) chronic kidney disease stage 5 (failure)
What can you not take with gemfibrozil?
Some products that may interact with this drug include: asunaprevir, "blood thinners" (such as warfarin), colchicine, repaglinide, "statin" drugs (such as atorvastatin, lovastatin, simvastatin). This medication can slow down the removal of other medications from your body, which may affect how they work.
How long should you take gemfibrozil?
Gemfibrozil is used for long-term treatment. Your doctor may decide to stop gemfibrozil after three months of therapy if you don't have enough change in your triglyceride levels. This drug comes with serious risks if you don't take it as prescribed.
Does gemfibrozil raise blood sugar?
Gemfibrozil treatment: 1) significantly reduces circulating triglyceride concentration; 2) does not significantly affect cholesterol concentration; 3) does not worsen glucose metabolism.
What causes high triglycerides?
Causes include obesity, eating too much unhealthy food, genetics, certain illnesses including poorly controlled diabetes, kidney disease, and underactive thyroid (hypothyroidism). Some drugs, such as steroids and birth control pills, and drinking a lot of alcohol can also cause it. Most people have no symptoms.
Does gemfibrozil cause constipation?
The most frequently reported side effects were gastrointestinal reactions and included dyspepsia, abdominal pain, diarrhea, nausea, vomiting, acute appendicitis, constipation, and flatulence.
How fast does gemfibrozil work?
It is very important to continue to follow your doctor's advice about diet and exercise. It may take up to 3 months before you get the full benefit of this drug.
Can gemfibrozil lower blood sugar?
Gemfibrozil treatment: 1) significantly reduces circulating triglyceride concentration; 2) does not significantly affect cholesterol concentration; 3) does not worsen glucose metabolism.
How long should you take gemfibrozil?
Gemfibrozil is used for long-term treatment. Your doctor may decide to stop gemfibrozil after three months of therapy if you don't have enough change in your triglyceride levels. This drug comes with serious risks if you don't take it as prescribed.
When is the best time to take gemfibrozil?
This medicine is usually taken two times a day. If you are taking two doses per day, it is best to take the medicine 30 minutes before your breakfast and evening meal. If you are taking colestipol, take it at least 2 hours before or after taking gemfibrozil.
Before Taking This Medicine
You should not use gemfibrozil if you are allergic to it, if you have: 1. severe liver disease; 2. severe kidney disease; 3. gallbladder disease; o...
How Should I Take Gemfibrozil?
Gemfibrozil is usually taken twice daily, 30 minutes before breakfast and dinner.Follow all directions on your prescription label. Do not take this...
Gemfibrozil Dosing Information
Usual Adult Dose for Hyperlipidemia:600 mg orally twice a day, 30 minutes before the morning and evening meal.See also: Dosage Information (in more...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...
What Should I Avoid While Taking Gemfibrozil?
Avoid eating foods that are high in fat or cholesterol. Gemfibrozil will not be as effective in lowering your cholesterol if you do not follow a ch...
What Other Drugs Will Affect Gemfibrozil?
Tell your doctor about all other medicines you use. Certain other drugs can increase your risk of serious muscle problems, and it is very important...
Is gemfibrozil (Lopid) a statin?
Gemfibrozil (Lopid) is a fibrate, which is a class of medications that help with cholesterol problems, especially high triglycerides. Statins also...
Can you drink alcohol while taking gemfibrozil (Lopid)?
It is best not to drink alcohol if you are taking gemfibrozil (Lopid). Drinking alcohol while taking gemfibrozil (Lopid) can increase your risk of...
Does gemfibrozil (Lopid) cause weight loss?
Some people who take gemfibrozil (Lopid) might experience weight loss, though this is not a common effect of the medication. Remember that it is be...
Why do you take gemfibrozil (Lopid) 30 minutes before meals?
Your body absorbs the most amount of gemfibrozil (Lopid) if you take it 30 minutes before a meal. If you take gemfibrozil (Lopid) after eating food...
Is gemfibrozil (Lopid) hard on the kidneys?
If you have kidney problems, taking gemfibrozil (Lopid) might make your kidneys worse. Talk to your provider if you have a history of kidney diseas...
How does Gemfibrozil work?
Gemfibrozil works by changing the amount of cholesterol and other fats (lipids) in your body. Gemfibrozil lowers triglyceride levels and raises HDL cholesterol levels. (HDL is considered a good type of cholesterol.)
How long after taking gemfibrozil can you take cholesterol medication?
Also, certain cholesterol drugs can decrease the effects of gemfibrozil. To prevent this, you should take these medications two hours or more after taking gemfibrozil. Examples of these drugs include:
Can you take gemfibrozil with Montelukast?
Montelukast is used to treat allergies and asthma. Taking gemfibrozil with it may increase your risk of side effects. Your doctor may lower your dosage of this drug if you need to take it with gemfibrozil.
Does Gemfibrozil make you sleepy?
Gemfibrozil doesn’t cause drowsiness, but it can cause other side effects.
Does Gemfibrozil lower triglycerides?
Gemfibrozil is used to lower your levels of triglycerides, a type of fat in your blood. Very high levels of triglycerides raise your risk of pancreatitis.
Can Gemfibrozil cause gallstones?
Gallstones warning: Gemfibrozil may cause you to develop gallstones. If you develop gallstones, you should stop using this drug.
Is Gemfibrozil a generic drug?
Gemfibrozil oral tablet is available as a brand-name drug and a generic drug. Brand name: Lopid.
How does Gemfibrozil work?
Gemfibrozil belongs to a group of drugs known as "fibrates.". It works by decreasing the amount of fat produced by the liver. Lowering triglycerides in people with very high triglyceride blood levels may decrease the risk of pancreas disease ( pancreatitis ).
How to take Gemfibrozil?
How to use Gemfibrozil. Take this medication by mouth as directed by your doctor, usually twice a day (30 minutes before your morning and evening meals). Dosage is based on your medical condition and response to treatment. If you also take certain other drugs to lower your cholesterol (bile acid-binding resins such as cholestyramine ...
How to report gemfibrozil side effects?
You may report side effects to Health Canada at 1-866-234-2345. Precautions. Before taking gemfibrozil, tell your doctor or pharmacist if you are allergic to it; or to other "fibrates" ...
Can you take gemfibrozil if you are allergic to it?
Before taking gemfibrozil, tell your doctor or pharmacist if you are allergic to it; or to other "fibrates" (such as fenofibrate ); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Are you currently using Gemfibrozil?
This survey is being conducted by the WebMD marketing sciences department.
What is Gemfibrozil used for?from go.drugbank.com
Gemfibrozil is a lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
Where did Gemfibrozil come from?from en.wikipedia.org
Gemfibrozil was selected from a series of related compounds synthesized in the laboratories of the American company Parke-Davis in the late 1970s. It came from research for compounds that lower plasma lipid levels in humans and in animals.
How long does Gemfibrozil last?from go.drugbank.com
Gemfibrozil has a plasma half-life of 1.5 hours. 11 In patients with renal failure the half life is 2.4h and in patients with liver disease the half life is 2.1h. 7
What is the volume of distribution of gemfibrozil?from go.drugbank.com
The volume of distribution of gemfibrozil is estimated to be 0.8L/kg. 10
Does Gemfibrozil increase the excretion rate of Solriamfetol?from go.drugbank.com
Gemfibrozil may decrease the excretion rate of Solriamfetol which could result in a higher serum level. The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Somatotropin is combined with Gemfibrozil. The metabolism of Sorafenib can be increased when combined with Gemfibrozil.
Can Gemfibrozil be combined with Mebeverine?from go.drugbank.com
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Gemfibrozil is combined with Mebeverine. Mecamylamine. Mecamylamine may decrease the excretion rate of Gemfibrozil which could result in a higher serum level.
Is Gemfibrozil a micropollutant?from en.wikipedia.org
This indicates that it survives the wastewater treatment process. It is also detected as environmental persistent micropollutant in aquifers and in groundwaters in karstic areas.
How to get rid of gemfibrozil?
To get maximum response from this treatment, follow a diet low in fats, and eat more vegetables, fruits, and whole grains. Try to exercise 3 to 4 times a week, for 40 minutes each time.
What is gemfibrozil (Lopid)?
Gemfibrozil (Lopid) is a fibrate. It works by helping to break down fats in the blood. This leads to the lowering of triglycerides (fats) and "bad" cholesterol (LDL) while increasing "good" cholesterol (HDL) in the body.
What are alternatives to gemfibrozil (Lopid)?
There are a number of medications that your doctor can prescribe in place of gemfibrozil (Lopid). Compare a few possible alternatives below.
Can Gemfibrozil interact with warfarin?
Gemfibrozil (Lopid) can interact with other medications which might be dangerous. If you are taking warfarin (Coumadin), let your provider or pharmacist know that you are also taking gemfibrozil (Lopid) and make sure to get your INR checked regularly.
Does gemfibrozil help with cholesterol?
Gemfibrozil (Lopid) is a fibrate, which is a class of medications that help with cholesterol problems, especially high triglycerides. Statins also help with cholesterol problems but work differently than gemfibrozil (Lopid). Can you drink alcohol while taking gemfibrozil (Lopid)?
Is Gemfibrozil a statin?
Gemfibrozil (Lopid) is an add-on medication to diet to lower triglycerides (fats) and "bad" cholesterol (LDL) while increasing "good" cholesterol (HDL), but may not be the best option if you're taking statins.
Is Gemfibrozil a serious drug?
Gemfibrozil (Lopid) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options
What Is Gemfibrozil and How Does It Work?
Gemfibrozil is used along with a proper diet to help lower fats ( triglycerides) and raise "good" cholesterol ( HDL) in the blood. It may also help to lower "bad" cholesterol ( LDL ). Gemfibrozil belongs to a group of drugs known as "fibrates." It works by decreasing the amount of fat produced by the liver. Lowering triglycerides in people with very high triglyceride blood levels may also decrease the risk of pancreas disease ( pancreatitis ). However, gemfibrozil might not lower your risk of a heart attack or stroke. Talk to your doctor about the risk and benefits of gemfibrozil.
What Other Drugs Interact with Gemfibrozil?
If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.
Does gemfibrozil cause cholelithiasis?
Cases of cholelithiasis reported with gemfibrozil therapy; gemfibrozil may increase cholesterol excretion into bile; if cholelithiasis suspected, perform gallbladder studies; discontinue therapy if gallstones found
Can you take gemfibrozil while pregnant?
Use gemfibrozil with caution during pregnancy if benefits outweigh risks. Animal studies show risk and human studies are not available or neither animal nor human studies were done. It is not known if gemfibrozil is excreted in breast milk; use caution if breastfeeding.
Does Gemfibrozil interact with warfarin?
warfarin. Gemfibrozil has moderate interactions with at least 31 different drugs. Mild interactions of gemfibrozil include: colestipol. ezetimibe. octacosanol. This information does not contain all possible interactions or adverse effects.
Does gemfibrozil cause dark urine?
Serious side effects of gemfibrozil include: Severe stomach/ abdominal pain. Persistent nausea or vomiting. Yellowing eyes or skin ( jaundice) Dark urine. This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
Does Gemfibrozil have any side effects?
Common Side effects of Gemfibrozil include: Less common side effects of gemfibrozil include: Serious side effects of gemfibrozil include: This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
How does this medication work? What will it do for me?
Gemfibrozil belongs to the class of medications known as fibrates. It is used to treat high cholesterol . It works by blocking the production of certain types of cholesterol, especially the type known as triglycerides.
What form (s) does this medication come in?
Gemfibrozil by Pro Doc is no longer being manufactured for sale in Canada. For brands that may still be available, search under gemfibrozil. This article is being kept available for reference purposes only. If you are using this medication, speak with your doctor or pharmacist for information about your treatment options.
Does gemfibrozil cause muscle breakdown?
Muscle effects: When combined with medications in the HMG-CoA reductase inhibitors class (commonly referred to as “statins”), there is an increased risk of muscle breakdown. If you are taking gemfibrozil and one of these medications, discuss with your doctor how this medication may affect your medical condition, and whether any special monitoring is needed.
Does Gemfibrozil lower cholesterol?
Gemfibrozil is used in combination with a healthy diet and exercise to lower cholesterol levels in the blood. Reduction of cholesterol levels has been shown to reduce the risks associated with heart disease, such as heart attack.
