what is the generic name for metoclopramide

Precautions

Metoclopramide is available under the following different brand names: Reglan, and Metozolv ODT. What Are Side Effects Associated with Using Metoclopramide? This is not a complete list of side effects and other serious side effects may occur. Call your doctor for information and medical advice about side effects.

What are the different brands of metoclopramide?

Metoclopramide side effects. Get emergency medical help if you have signs of an allergic reaction to metoclopramide: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

What are the side effects of metoclopramide?

Metoclopramide IV is approved by the FDA for pediatric use to facilitate small bowel intubation by causing gastric emptying where delayed gastric emptying interferes with radiological examination of the stomach and/or small intestine. What happens if I miss a dose?

What does metoclopramide mean?

PMID 16882832. S2CID 21568481. ^ a b c d "FDA requires boxed warning and risk mitigation strategy for metoclopramide-containing drugs" (Press release). U.S. Food and Drug Administration. 26 February 2009.

What is the PMID for metoclopramide?

What is metoclopramide?

How long can you take metoclopramide?

What other drugs will affect metoclopramide?

Where is metoclopramide given?

What is the name of the bronchodilator?

What happens if you are allergic to metoclopramide?

Is metoclopramide safe for children?

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What is the brand name of metoclopramide?

What is metoclopramide? Metoclopramide oral tablet is a prescription drug that's available as the brand-name drugs Reglan and Metozolv ODT. It's also available as a generic drug. Generic drugs usually cost less than brand-name versions.

What is metoclopramide given for?

Metoclopramide is an anti-sickness medicine (known as an antiemetic). It's used to help stop you feeling or being sick (nausea or vomiting) including: after radiotherapy or chemotherapy (treatment for cancer) sickness you may get with a migraine.

Is Zofran and metoclopramide the same thing?

Are Zofran and Reglan the Same Thing? Zofran (ondansetron) and Reglan (metoclopramide) are antiemetics (anti-nausea and vomiting) used to treat nausea and vomiting. Zofran is often used to prevent and treat nausea and vomiting during chemotherapy and after surgery.

What is metoclopramide 10 mg used for?

Metoclopramide is used to treat the symptoms of slow stomach emptying (gastroparesis) in patients with diabetes. It works by increasing the movements or contractions of the stomach and intestines. It relieves symptoms such as nausea, vomiting, heartburn, a feeling of fullness after meals, and loss of appetite.

What drugs should not be taken with metoclopramide?

Some products that may interact with this drug are: antipsychotic drugs (such as aripiprazole, haloperidol), atovaquone, dopamine agonists (such as cabergoline, pergolide, ropinirole), fosfomycin, MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, ...

Who should not take metoclopramide?

talk to your doctor about the risks and benefits of taking metoclopramide if you are 65 years of age or older. Older adults should not usually take metoclopramide, unless it is used to treat slow stomach emptying, because it is not as safe or effective as other medications that can be used to treat those conditions.

What is the strongest anti-nausea medication?

One of the most effective anti-nausea medications is Zofran (ondansetron) which was developed to solve this problem. Zofran is available as tablets, dissolvable tablets, strips, or liquid. While it is safe for the general population, it is so effective, that it is also used in patients undergoing chemotherapy.

What is the best prescription medicine for nausea?

Prochlorperazine (or brand name Stemetil®) is one of the most used medicines for nausea. It works for many common causes of nausea, including vertigo, ear problems and sickness in pregnancy.

What is the best medicine for nausea?

Several OTC medicines are used as antiemetics. These include: Bismuth subsalicylate (2 brand names: Kaopectate, Pepto-Bismol). This medicine may help treat some types of nausea and vomiting, such as from gastroenteritis (stomach flu).

What are the side effects of metoclopramide 10 mg?

Common metoclopramide side effects may include:feeling restless;feeling drowsy or tired;lack of energy;nausea, vomiting;headache, confusion; or.sleep problems (insomnia).

How quickly does metoclopramide work?

Metoclopramide takes about one to three minutes to start working following an intravenous dose; 10-15 minutes following an intramuscular dose; and 30-60 minutes following an oral dose. Effects last for approximately one to two hours.

Can you buy metoclopramide over the counter?

It is only available with a prescription. For migraines, you can also get metoclopramide combined with a painkiller with a prescription.

How quickly does metoclopramide work?

Metoclopramide takes about one to three minutes to start working following an intravenous dose; 10-15 minutes following an intramuscular dose; and 30-60 minutes following an oral dose. Effects last for approximately one to two hours.

Is metoclopramide used for acid reflux?

Metoclopramide is also used to treat heartburn for patients with gastroesophageal reflux disease (GERD). GERD is esophageal irritation from the backward flow of gastric acid into the esophagus.

Is metoclopramide a muscle relaxer?

Metoclopramide causes airway smooth muscle relaxation through inhibition of muscarinic M3 receptor in the rat trachea. Anesth Analg. 2004 May;98(5):1325-9, table of contents. doi: 10.1213/01.

Is metoclopramide a sedative?

Background. Metoclopramide is a dopamine D2-receptor antagonist used as an antiemetic and gastroprokinetic agent in man and animals. The drug causes sedation as a side effect in man.

Metoclopramide: 7 things you should know - Drugs.com

Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 12 Oct 2022), Cerner Multum™ (updated 21 Sep 2022), ASHP (updated 12 Oct 2022 ...

Metoclopramide | Side Effects, Dosage, Uses, and More - Healthline

Metoclopramide oral tablet may cause drowsiness. Some people may have dizziness, nervousness, or headaches after they stop taking this drug. It can also cause other side effects.

Metoclopramide Side Effects: Common, Severe, Long Term - Drugs.com

Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 12 Oct 2022), Cerner Multum™ (updated 21 Sep 2022), ASHP (updated 12 Oct 2022 ...

Metoclopramide (Oral Route) Side Effects - Mayo Clinic

Side Effects. Drug information provided by: IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Metoclopramide: Uses, Interactions, Mechanism of Action - DrugBank

Generic Name Metoclopramide DrugBank Accession Number DB01233 Background. Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. 6 Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition ...

What is metoclopramide used for?

Metoclopramide is used to treat gastroesophageal reflux disease (GERD) that causes symptoms. GERD occurs when acid flows up from your stomach. This causes heartburn. It may also harm your esophagus (the tube that connects your mouth to your stomach). This drug is used to relieve heartburn and heal sores in your esophagus when other treatments haven’t worked.

How to store metoclopramide?

Store metoclopramide at room temperature. Keep it between 68°F and 77°F (20°C and 25°C).

What to do if you don't feel better after taking metoclopramide?

Metoclopramide oral tablet comes with several warnings. Call your doctor if your symptoms don’t improve after taking this drug.

Is metoclopramide an oral solution?

Metoclopramide also comes in an oral solution as well as injectable forms that are only given to you by a healthcare provider.

Can metoclopramide cause headaches?

Metoclopramide oral tablet may cause drowsiness. Some people may have dizziness, nervousness, or headaches after they stop taking this drug. It can also cause other side effects.

Is metoclopramide a generic drug?

Metoclopramide oral tablet is a prescription drug that’s available as the brand-name drugs Reglan and Metozolv ODT. It’s also available as a generic drug. Generic drugs usually cost less than brand- name versions. In some cases, they may not be available in all strengths or forms as a brand-name drug.

Is metoclopramide a tablet?

This dosage information is for metoclopramide oral tablet. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

What are the side effects of metoclopramide?

Diabetes, age, and female gender are risk factors that increase the likelihood of experiencing a neuropsychiatric side effect of metoclopramide. Panic Disorder. Major depressive disorder. Agoraphobia.

When was metoclopramide first used?

Metoclopramide was first described by Louis Justin-Besançon and Charles Laville in 1964, while working to improve the anti-dysrhythmic properties of procainamide. That research project also produced the product sulpiride. The first clinical trials were published by Tourneu et al. in 1964 and by Boisson and Albot in 1966. Justin-Besançon and Laville worked for Laboratoires Delagrange and that company introduced the drug as Primperan in 1964. Laboratoires Delagrange was acquired by Synthelabo in 1991 which eventually became part of Sanofi.

What is the black box warning for metoclopramide?

In 2009, the FDA required all manufacturers of metoclopramide to issue a black box warning regarding the risk of tardive dyskinesia with chronic or high-dose use of the drug. Dystonic reactions may be treated with benzatropine, diphenhydramine, trihexyphenidyl, or procyclidine.

How long after metoclopramide do you see side effects?

Side effects were usually seen in the first 15 min after the dose of metoclopramide.

Does metoclopramide cause nausea?

The antiemetic action of metoclopramide is due to its antagonist activity at D 2 receptors in the chemoreceptor trigger zone in the central nervous system — this action prevents nausea and vomiting triggered by most stimuli. At higher doses, 5-HT 3 antagonist activity may also contribute to the antiemetic effect.

Can metoclopramide be taken with aspirin?

In migraine headaches, metoclopramide may be used in combination with paracetamol (acetaminophen) or in combination with aspirin.

Is metoclopramide a generic?

It belongs to the group of medications known as dopamine-receptor antagonists and works as a prokinetic. In 2012, metoclopramide was one of the top 100 most prescribed medications in the United States. It is available as a generic medication. It is on the World Health Organization's List of Essential Medicines.

Product (s) containing metoclopramide

Brand names: Reglan, Maxolon, Gimoti, Metozolv ODT Drug class (es): GI stimulants, miscellaneous antiemetics Metoclopramide systemic is used in the treatment of:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

How long can you take metoclopramide?

Do not use metoclopramide products for longer than 12 weeks. Talk to your doctor about the risks and benefits of this medication. Tell your doctor right away if you develop any unusual uncontrolled movements (especially of the face, mouth, tongue, arms or legs).

How long does metoclopramide last?

This medication is used to treat certain conditions of the stomach and intestines. Metoclopramide is used as a short-term treatment (4 to 12 weeks) for ongoing heartburn when the usual medicines do not work well enough. It is used mostly for heartburn that occurs after a meal or during the daytime.

How to report metoclopramide side effects in Canada?

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Precautions. Before taking metoclopramide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.

Can metoclopramide cause tardive dyskinesia?

The risk of tardive dyskinesia is increased with the longer use of the medication and the more medication that you take. The risk is also increased in older adults (especially women) and in people with diabetes. Metoclopramide comes in different forms (such as solution, injection). Do not use metoclopramide products for longer than 12 weeks. Talk to your doctor about the risks and benefits of this medication.

Can metoclopramide be lowered?

To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used metoclopramide for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal. Tell your doctor if your condition lasts or gets worse. Side Effects.

Are you currently using Metoclopramide 10 Mg Disintegrating Tablet GI Stimulants?

This survey is being conducted by the WebMD marketing sciences department.

What Is Metoclopramide and How Does It Work?

Metoclopramide is used to treat certain conditions of the stomach and intestines. Metoclopramide is used as a short-term treatment (4 to 12 weeks) for persistent heartburn when the usual medicines do not work well enough. It is used mostly for heartburn that occurs after a meal or during the daytime. Treating persistent heartburn can decrease the damage done by stomach acid to the swallowing tube ( esophagus) and help healing.

How to report metoclopramide side effects?

Call your doctor for information and medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Why is metoclopramide used for cancer?

Metoclopramide may also be used to prevent nausea/vomiting from chemotherapy or radiation treatments for cancer.

How many drugs interact with metoclopramide?

Metoclopramide has moderate interactions with at least 39 different drugs.

Does Metoclopramide help with heartburn?

Treating persistent heartburn can decrease the damage done by stomach acid to the swallowing tube ( esophagus) and help healing. Metoclopramide is also used in diabetic patients who have poor emptying of their stomachs ( gastroparesis ). Treating gastroparesis can decrease symptoms of nausea, vomiting, and stomach/ abdominal fullness.

Can you take metoclopramide for kids?

Metoclopramide is not recommended for use in children younger than 1 year due to an increased risk of serious side effects (such as muscle spasms/uncontrolled muscle movements). Ask the doctor or pharmacist for details. Metoclopramide may also be used to prevent nausea/vomiting from chemotherapy or radiation treatments for cancer.

Is metoclopramide safe for pregnancy?

Metoclopramide may be acceptable for use during pregnancy. Either animal studies show no risk but human studies are not available or animal studies showed minor risks and human studies were done and showed no risk. No association was observed between exposure to metoclopramide during pregnancy and an increased risk of birth defects, spontaneous abortion, or stillbirth, according to results of a large, register-based study [ JAMA 2013 310 (15)]. Other studies have also shown no association with first trimester use and major congenital malformations [N Engl J Med 2009 360 (24)].

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

How long can you take metoclopramide?

NEVER USE METOCLOPRAMIDE IN LARGER AMOUNTS THAN RECOMMENDED, OR FOR LONGER THAN 12 WEEKS. High doses or long-term use can cause a serious movement disorder that may not be reversible. The longer you use metoclopramide, the more likely you are to develop this movement disorder. The risk of this side effect is higher in diabetics and older adults (especially women).

What is Reglan?

Reglan (metoclopramide) increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines and may help with nausea.

How should I use Reglan?

Take Reglan exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Use the medicine exactly as directed.

Can you take Reglan if you have a seizure?

Do not use Reglan if you've ever had muscle movement problems after using metoclopramide or similar medicines, or if you've had a movement disorder called tardive dyskinesia. You also should not use this medicine if you've had stomach or intestinal problems (a blockage, bleeding, or a hole or tear), epilepsy or other seizure disorder, or an adrenal gland tumor ( pheochromocytoma ).

Can metoclopramide cause movement problems?

High doses or long-term use of metoclopramide can cause a serious movement disorder that may not be reversible. The longer you use metoclopramide, the more likely you are to develop this movement disorder. The risk of this side effect is higher in diabetics and older adults (especially women).

Does Reglan help with stomach pain?

Reglan is also used to treat gastroparesis (slow stomach emptying) in people with diabetes, which can cause heartburn and stomach discomfort after meals.

What is metoclopramide?

Metoclopramide increases muscle contractions in the upper digestive tract. This speeds up the rate at which the stomach empties into the intestines.

How long can you take metoclopramide?

NEVER USE METOCLOPRAMIDE IN LARGER AMOUNTS THAN RECOMMENDED, OR FOR LONGER THAN 12 WEEKS. High doses or long-term use can cause a serious movement disorder that may not be reversible. The longer you use metoclopramide, the more likely you are to develop this movement disorder. The risk of this side effect is higher in diabetics and older adults (especially women).

What other drugs will affect metoclopramide?

Using metoclopramide with other drugs that make you drowsy can worsen this effect. Ask your doctor before you take opioid pain medication, a sleeping pill, a muscle relaxer, or medicine for anxiety, depression, or seizures.

Where is metoclopramide given?

A metoclopramide injection is given into a muscle or as an infusion into a vein. A healthcare provider will give the injection, usually during surgery, chemotherapy, or a medical procedure.

What is the name of the bronchodilator?

bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);

What happens if you are allergic to metoclopramide?

Get emergency medical help if you have signs of an allergic reaction to metoclopramide: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Is metoclopramide safe for children?

Metoclopramide is not approved by the FDA for gastroesophageal reflux disease in pediatric patients; however, the following doses have been studied:#N#Oral, IM, IV:#N#Infants and Children: 0.4 to 0.8 mg/kg/day in 4 divided doses

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