Precautions
What class of drug is Nardil?
Nardil is a prescription medicine used to treat the symptoms of Depression. Nardil may be used alone or with other medications. Nardil belongs to a class of drugs called Antidepressants, MAO Inhibitors.
What is another name for Nardil?
Nardil (phenelzine) is a monoamine oxidase inhibitor (MAOI), a type of antidepressant, used to treat symptoms of depression that may include feelings of sadness, fear, anxiety, or worry about physical health (hypochondria).
Is Nardil a good antidepressant?
A tally of 8,000 respondents to a poll on “Askapatient.com” shows Nardil the best antidepressant, tied with another MAOI.
What are the effects of Nardil?
Dizziness, drowsiness, tiredness, weakness, problems sleeping, constipation, and dry mouth may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly.
Why did Pfizer change Nardil?
Nardil was changed in late 2003, due to a complete reformulation by Pfizer, who removed many of the excipient ingredients, including the hard coating. It is possible that the current version is not surviving the stomach acid content and therefore not as much is being absorbed into the bloodstream.
Is Nardil a mood stabilizer?
Phenelzine is an antidepressant medication that works in the brain. It is approved for the treatment of major depressive disorder (MDD). Symptoms of depression include: Depressed mood - feeling sad, empty, or tearful.
Is Nardil still available?
Despite supply issues and delays, manufacturer ERFA has confirmed that Nardil has not been discontinued, and the shortage is only related to the medication's active ingredient.
What foods should be avoided when taking Nardil?
Do not eat foods that have dopamine and a high tyramine content (most common in foods that are aged or fermented to increase their flavor), such as cheese (especially strong or aged kinds), caviar, sour cream, liver, canned figs, soy sauce, sauerkraut, fava beans, yeasts, and yogurt.
Does Nardil affect blood pressure?
Dangerously high blood pressure MAOI medications, like phenelzine (Nardil), can cause your blood pressure to become too high, which in some cases can be fatal.
Does Nardil make you gain weight?
Some monoamine oxidase inhibitors (MAOIs) MAOIs that cause weight gain include: phenelzine (Nardil)
Is Nardil sedating?
The mental health side effects of Nardil can include somnolence, lethargy, sedation, anorexia, insomnia, and, in rare cases, mania, hypomania, and psychosis.
Can Nardil cause mania?
On rare occasions, treatment with Nardil can cause psychosis, mania, and acute liver failure.
Does Nardil cause weight gain?
Some monoamine oxidase inhibitors (MAOIs) MAOIs that cause weight gain include: phenelzine (Nardil)
What medications should not be taken with phenelzine?
Some products that may interact with this drug include: other antidepressants (including maprotiline, mirtazapine, nefazodone, TCAs such as amitriptyline/nortriptyline), appetite suppressants (such as diethylpropion), drugs for attention deficit disorder (such as atomoxetine, methylphenidate), apraclonidine, bupropion, ...
What is the generic name for Parnate?
Tranylcypromine (Parnate) is a monoamine oxidase inhibitor (MAOI). It blocks a protein in your brain that breaks down certain chemicals, such as norepinephrine, dopamine, and serotonin. This allows these chemicals to stay in your brain longer, which can help improve your mood.
What is the contraindications for Nardil?
NARDIL should not be used in patients who are hypersensitive to the drug or its ingredients, with pheochromocytoma, congestive heart failure, severe renal impairment or renal disease, a history of liver disease, or abnormal liver function tests.
What is nardil used for?
Nardil is a monoamine oxidase inhibitor (MAOI) that is used to treat symptoms of atypical depression in adults when other medicines have not been effective. Nardil is not for treating severe depression or bipolar disorder (manic depression). Nardil may also be used for purposes not listed in this medication guide.
What other drugs will affect Nardil?
When you start or stop taking Nardil, your doctor may need to adjust the doses of any other medicines you take on a regular basis.
How should I take Nardil?
Follow all directions on your prescription label and read all medication guides or instruction sheets . Your doctor may occasionally change your dose. Use the medicine exactly as directed.
How long before Nardil can you take it?
A dangerous drug interaction can occur between Nardil and certain other medicines you use within 14 days before or after taking this medicine.
Can Nardil cause high blood pressure?
Report any new or worsening symptoms to your doctor. There are many other drugs, foods, and beverages that can cause dangerously high blood pressure if you take them together with Nardil. Tell your doctor about all your current medicines and any you start or stop using.
Can you stop Nardil?
Do not stop using Nardil suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.
Can you eat chocolate while taking Nardil?
excessive amounts of chocolate or caffeine. Eating these foods while you are taking Nardil can raise your blood pressure to dangerous levels, causing life-threatening side effects. Also avoid these foods for 2 weeks after you stop taking this medicine. Nardil may impair your thinking or reactions.
What is Nardil used for?
Nardil is a prescription medicine used to treat the symptoms of Depression. Nardil may be used alone or with other medications.
What is the molecular weight of NARDIL?
NARDIL ® (phenelzine sulfate) is a potent inhibitor of monoamine oxidase (MAO). Phenelzine sulfate is a hydrazine derivative. It has a molecular weight of 234.27 and is chemically described as C 8 H 12 N 2 • H 2 SO 4. Its chemical structure is shown below:
How long after discontinuing Nardil can you eat?
All patients should be warned that the following foods, beverages, and medications must be avoided while taking NARDIL, and for two weeks after discontinuing use.
What are the side effects of Nardil?
Get medical help right away, if you have any of the symptoms listed above. The most common side effects of Nardil include: dizziness, drowsiness, weakness, sleep problems (insomnia),
Is Nardil effective for depression?
NARDIL has been found to be effective in depressed patients clinically characterized as "atypical," " nonendogenous," or " neurotic." These patients often have mixed anxiety and depression and phobic or hypochondriacal features. There is less conclusive evidence of its usefulness with severely depressed patients with endogenous features.
Can you take Nardil while pregnant?
Use in Pregnancy. The safe use of NARDIL during pregnancy or lactation has not been established.
How to report side effects of prescription drugs?
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
What should a prescriber know about Nardil?from rxlist.com
Prescribers or other health professionals should inform patients, their families, and their caregivers about the benefits and risks associated with treatment with Nardil and should counsel them in its appropriate use . A patient Medication Guide about "Antidepressant Medicines, Depression and other Serious Mental Illness, and Suicidal Thoughts or Actions" is available for Nardil. The prescriber or health professional should instruct patients, their families, and their caregivers to read the Medication Guide and should assist them in understanding its contents. Patients should be given the opportunity to discuss the contents of the Medication Guide and to obtain answers to any questions they may have. The complete text of the Medication Guide is reprinted at the end of this document.
What is the molecular weight of nardil?from rxlist.com
Nardil ® (phenelzine sulfate) is a potent inhibitor of monoamine oxidase (MAO). Phenelzine sulfate is a hydrazine derivative. It has a molecular weight of 234.27 and is chemically described as C 8 H 12 N 2 • H 2 SO 4. Its chemical structure is shown below:
How should I take Nardil?from drugs.com
Follow all directions on your prescription label and read all medication guides or instruction sheets . Your doctor may occasionally change your dose. Use the medicine exactly as directed.
What other drugs will affect Nardil?from drugs.com
When you start or stop taking Nardil, your doctor may need to adjust the doses of any other medicines you take on a regular basis.
What is the most important reaction associated with Nardil administration?from rxlist.com
The most important reaction associated with NARDIL administration is the occurrence of hypertensive crises, which have sometimes been fatal.
How much phenelzine is in Nardil?from drugs.com
Each Nardil tablet is orange, biconvex, film-coated, and engraved with "P-D 270" and contains phenelzine sulfate equivalent to 15 mg of phenelzine base.
How long does it take for nardil to show signs of depression?from drugs.com
Signs and symptoms may be absent or minimal during the initial 12-hour period following ingestion and may develop slowly thereafter, reaching a maximum in 24–48 hours. Death has been reported following overdosage. Therefore, immediate hospitalization, with continuous patient observation and monitoring throughout this period, is essential.
What is the molecular weight of nardil?
Nardil ® (phenelzine sulfate) is a potent inhibitor of monoamine oxidase (MAO). Phenelzine sulfate is a hydrazine derivative. It has a molecular weight of 234.27 and is chemically described as C 8 H 12 N 2 • H 2 SO 4. Its chemical structure is shown below:
What are the most serious reactions to Nardil?
The most serious reactions to Nardil involve changes in blood pressure.
How long does it take for nardil to show signs of depression?
Signs and symptoms may be absent or minimal during the initial 12-hour period following ingestion and may develop slowly thereafter, reaching a maximum in 24–48 hours. Death has been reported following overdosage. Therefore, immediate hospitalization, with continuous patient observation and monitoring throughout this period, is essential.
How long does it take for a man to recover from a lethal overdose?
With symptomatic and supportive measures, recovery from mild overdosage may be expected within 3 to 4 days.
Is Nardil the first antidepressant?
Nardil should rarely be the first antidepressant drug used. Rather, it is more suitable for use with patients who have failed to respond to the drugs more commonly used for these conditions.
Can you take nardil with pheochromocytoma?
Nardil should not be used in patients who are hypersensitive to the drug or its ingredients, with pheochromocytoma, congestive heart failure, severe renal impairment or renal disease, a history of liver disease, or abnormal liver function tests.
Can Nardil be taken with sympathomimetic drugs?
Therefore, patients being treated with Nardil should not take sympathomimetic drugs (including amphetamines, cocaine, methylphenidate, dopamine, epinephrine, and norepinephrine) or related compounds (including methyldopa, L-dopa, L-tryptophan, L-tyrosine, and phenylalanine).
warnings
You should not use phenelzine if you are allergic to it, or if you have:
Side Effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Dosage Guidelines & Tips
Use Nardil (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Overdose Signs
If you think you or someone else may have overdosed on: Nardil (Oral) , call your doctor or the Poison Control center
What is phenelzine (Nardil)?
Phenelzine (Nardil) is a monoamine oxidase inhibitor ( MAOI). It blocks a protein in your brain that breaks down certain chemicals, such as norepinephrine, dopamine, and serotonin. This allows these chemicals to stay in your brain longer, which can help improve your mood.
What are the side effects of phenelzine (Nardil)?
With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.
Is Nardil effective for depression?
NARDIL has been found to be effective in depressed patients clinically characterized as“atypical,” “nonendogenous,” or “neurotic.” These patients often have mixed anxiety anddepression and phobic or hypochondriacal features. There is less conclusive evidence ofits usefulness with severely depressed patients with endogenous features.
Is Nardil a monoamine oxidase inhibitor?
NARDIL is a potent inhibitor of monoamine oxidase. Because this enzyme is widelydistributed throughout the body, diverse pharmacologic effects can be expected to occur.When they occur, such effects tend to be mild or moderate in severity (see below), oftensubside as treatment continues, and can be minimized by adjusting dosage; rarely is itnecessary to institute counteracting measures or to discontinue NARDIL.
What Is Phenelzine and How Does It Work?
Phenelzine is a prescription medicine used to treat the symptoms of depression.
What Are Side Effects Associated with Using Phenelzine?
This is not a complete list of side effects and other serious side effects or health problems that may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.
What Other Drugs Interact with Phenelzine?
If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first
