What is the molar mass of acetanilide?
C 8 H 9 N O Molar mass 135.166 g·mol −1 Odor Odorless Density 1.219 g/cm 3 Melting point 113–115 C (235–239 F; 386–388 K) Boiling point 304 C (579 F; 577 K) Acetanilide is an odourless solid chemical of leaf or flake-like appearance. It is also known as N-phenylacetamide, acetanil, or acetanilid, and was formerly known by the trade name Antifebrin
What is acetanilide?
Acetanilide crystals on a watch glass Acetanilide is an odourless solid chemical of leaf or flake-like appearance. It is also known as N-phenylacetamide, acetanil, or acetanilid, and was formerly known by the trade name Antifebrin.
What is the standard state of acetanilide in KPA?
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ?) Acetanilide [7] is an odourless solid chemical of leaf or flake-like appearance. It is also known as N-phenylacetamide, acetanil, or acetanilid, and was formerly known by the trade name Antifebrin .
What is the difference between acetanilide and acetylarylamine?
Acetanilide is a white to gray solid. (NTP, 1992) N-Acetylarylamine is an odourless solid chemical of leaf or flake-like appearance. It is also known as acetanilide, N-phenylacetamide, acetanil, or acetanilid, and was formerly known by the trade name Antifebrin.
What is the melting point of acetanilide in Celsius?
113.7 ºCPhysical-chemical properties of acetanilide are as follows: melting point 113.7 ºC, boiling point 304 ºC at 760 mmHg, water solubility 4 g/L at 20 ºC, Log Pow 1.16 at 23 ºC.
What is the lit value of the melting point for acetanilide?
113-115 °C(lit.)
What is the melting point of purified acetanilide?
114oC.The melting point of pure acetanilide is reported as 114oC. A pure compound melts over a narrow range of 1-3 oC near its reported melting point. laboratory. Weigh about 2 g of impure acetanilide [Data Sheet] and place it into a 100-mL beaker (label as Beaker 1).
What is the density of acetanilide in g mL?
1.214 g/mLSpecific Gravity 1.214 g/mL @ 20°C.
How do you determine melting point?
The melting point of an organic solid can be determined by introducing a tiny amount into a small capillary tube, attaching this to the stem of a thermometer centred in a heating bath, heating the bath slowly, and observing the temperatures at which melting begins and is complete.
What is melting point?
Melting point is the temperature at which a given solid material changes from a solid state to a liquid, or melts.
Does acetanilide dissolve in water?
WaterBenzeneEthanolAcetoneDiethyl etherAcetanilide/Soluble in
What is the boiling point of acetanilide?
579.2°F (304°C)Acetanilide / Boiling point
Why is acetanilide good for recrystallization?
The crude solid is dissolved in the smallest possible amount of solvent of choice; in this case the solvent is water. Acetanilide has a much higher solubility in hot water than in cold water. The purified solid will not recrystallize later in the experiment if too much hot solvent is added in the beginning.
Is acetanilide soluble in hot water?
Acetanilide is moderately soluble in boiling water, but it's much less soluble in room temperature and cold water. Aniline, a potential impurity, is much more soluble in room temperature water. Thus, you'll first make a saturated solution of acetanilide in boiling water.
What is the Colour of acetanilide?
whiteAcetanilide is a white organic solid compound used primarily in organic synthesis.
Is acetanilide a base or acid?
Acetanilide is the neutral compound in the mixture. Since it is neutral, it will not react with any inorganic base or acid.
What is melting point of P Nitroacetanilide?
213°C to 216°CSpecificationsCAS Min %98.5ColorBrown-Green or Green-Yellow to YellowMelting Point213°C to 216°CAssay Percent Range99%Infrared SpectrumAuthentic12 more rows
What is the boiling point of acetanilide?
579.2°F (304°C)Acetanilide / Boiling point
What is the melting point of P Bromoacetanilide?
166.0°C to 170.0°CSpecificationsCAS Min %97.5Melting Point166.0°C to 170.0°CAssay Percent Range97.5% min. (GC)Infrared SpectrumAuthenticLinear FormulaCH3CONHC6H4Br12 more rows
What is the formula of acetanilide?
C8H9NOAcetanilide / Formula
What is acetanilide used for?
Acetanilide is used as an inhibitor of hydrogen peroxide decomposition and is used to stabilize cellulose ester varnishes. It has also found uses in the intermediation in rubber accelerator synthesis, dyes and dye intermediate synthesis, and camphor synthesis. Acetanilide is used for the production of 4-acetamidobenzenesulfonyl chloride, a key intermediate for the manufacture of the sulfa drugs.
Is acetanilide a drug?
Acetanilide was the first aniline derivative found to possess analgesic as well as antipyretic properties, and was quickly introduced into medical practice under the names of Antifebrin by A. Cahn and P. Hepp in 1886. But its (apparent) unacceptable toxic effects, the most alarming being cyanosis due to methemoglobinemia and ultimately liver and kidney damage, prompted the search for supposedly less toxic aniline derivatives such as phenacetin. After several conflicting results over the ensuing fifty years, it was established in 1948 that acetanilide was mostly metabolized to paracetamol (acetaminophen) in the human body, and that it was this metabolite that was responsible for the analgesic and antipyretic properties. The observed methemoglobinemia after acetanilide administration was ascribed to the small proportion of acetanilide that is hydrolyzed to aniline in the body. Acetanilide is no longer used as a drug in its own right, although the success of its metabolite – paracetamol (acetaminophen) – is well known (although it is itself toxic in excessive amounts ).
Is paracetamol safer than acetaminophen?
^ The presence of aniline as an impurity in 19th century batches of acetanilide drugs cannot be ruled out. In this sense as well, paracetamol (acetamino phen) is safer than acetanilide, as (1) the corresponding impurity would be 4-aminophenol, which is less toxic than aniline; and (2) in vivo hydrolysis of the amide group in paracetamol appears to be negligible.
