What is the melting point of trimyristin after recrystallization?
After the recrystallization, a melting point between 55-56 °C is achieved for the product. Some of the material was used for the hydrolysis, but what was used to recrystallize gave a 72.91% yield. The melting point range decreased by 1 °C and moved closer to the literature range for trimyristin.
What is trimyristin and where is it found?
Trimyristin is found naturally in many vegetable fats and oils . The isolation of trimyristin from powdered nutmeg is a common introductory-level college organic chemistry experiment. It is an uncommonly simple natural product extraction because nutmeg oil generally consists of over eighty percent trimyristin.
Is trimyristin soluble in ethanol?
It is a [ [saturated fat which is the triglyceride of myristic acid. Trimyristin is a white to yellowish-gray solid that is insoluble in water, but soluble in ethanol, acetone, benzene, chloroform, dichloromethane, ether, and TBME .
What is the isolation of trimyristin from powdered nutmeg?
The isolation of trimyristin from powdered nutmeg is a common introductory-level college organic chemistry experiment. It is an uncommonly simple natural product extraction because nutmeg oil generally consists of over eighty percent trimyristin.
What is trimyristin melting point?
591.8°F (311°C)Trimyristin / Boiling point
What is the physical state of pure trimyristin at room temperature?
Pure trimyristin is a liquid at room temperature. ether. d. Trimyristin is more soluble in acetone than in diethyl ether.
What is the structure of trimyristin?
C45H86O6Trimyristin / Formula
What is the maximum amount of trimyristin recoverable from your sample of nutmeg?
Trimyristin is found in the fixed oil of nutmeg. The fixed oil comprises approximately 24-40% of the nutmeg seed. Trimyristin comprises 73% of the fixed oil. Overall, trimyristin should have a percent recovery of 18-29%.
Is trimyristin liquid at room temperature?
Pure trimyristin is a liquid at room temperature. b. According to the equation defining the distribution coefficient K, a value of 2 for K means that A is more soluble in solvent So than in solvent Sx.
What is pure trimyristin?
Trimyristin is a triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by myristic (tetradecanoic) acid. It is a triglyceride and a tetradecanoate ester. ChEBI. Trimyristin is a natural product found in Horsfieldia irya, Staudtia kamerunensis, and other organisms with data available.
What is trimyristin used for?
Presently, the main use of trimyristin is for research and development as a laboratory reagent.
What are the melting points of both trimyristin and myristic acid?
The dried sample also had the melting point taken and was recorded at 54 °C. The literature gives a melting point value of 54.4 °C for myristic acid, so the product of hydrolysis and acid addition can be identified as such.
Is trimyristin polar or nonpolar?
nonpolarTrimyristin consists of long saturated hydrocarbon chains and it is relatively nonpolar. Thus using a relatively nonpolar solvent, trimyristin can be easily extracted by the concept of "like dissolves like".
What is the theoretical yield of trimyristin from nutmeg?
The theoretical yield would be 55 mg of myristic acid and 41mg of product was collected.
Is water a good solvent for trimyristin?
Water would not be suitable or extracting trimyrisitn from nutmeg because it is insoluble in water. Trimyristin in insoluble in water because it has a long chain of C-H groups which takes this compound nonpolar.
Does trimyristin make nutmeg smell?
Trimyristin is one of a number of natural products found in nutmeg, including the one which gives it its characteristic odor.
Does trimyristin have a boiling point?
591.8°F (311°C)Trimyristin / Boiling point
What kind of fat is trimyristin?
saturated fatTrimyristin is an ester with the chemical formula C45H86O6. It is a saturated fat which is the triglyceride of myristic acid. Trimyristin is found naturally in many vegetable fats and oils.
Why is trimyristin insoluble in water?
Trimyristin in insoluble in water because it has a long chain of C-H groups which takes this compound nonpolar.
Why is trimyristin a saturated fat?
Trimiyristin is indeed classified as a saturated fat. If the carboxylic acid portion of the fat contains no alkene groups, then the fat can be said to be saturated. If one alkene group is present then we can classify the fat as polyunsaturated.
How much trimyristin is in nutmeg oil?
It is an uncommonly simple natural product extraction because nutmeg oil generally consists of over eighty percent trimyristin. Trimyristin makes up between 20-25% of the overall mass of dried, ground nutmeg.
What is the formula for trimyristin?
Chemical compound. Trimyristin is an ester with the chemical formula C 45 H 86 O 6. It is a saturated fat which is the triglyceride of myristic acid. Trimyristin is a white to yellowish-gray solid that is insoluble in water, but soluble in ethanol, benzene, chloroform, dichloromethane, and ether .
Use of Trimyristin
Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC50s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively [1].
Synthetic Route
Literature: Chemische Berichte, , vol. 68, p. 747 Journal of the Chemical Society, , p. 670 Journal of the Chemical Society, , p. 987
Why is my melting point low?
The low melting point in this case can most likely be attributed to either methylene chloride that was not distilled from the trimyristin or acetone that did not completely evaporate from the trimyristin.
What solvent is used to extract trimyristin?
To extract the trimyristin we performed a solid-liquid extraction using the organic solvent Methylene Chloride (CH2Cl2) . We use methylene chloride to extract the trimyristin because both are relatively non-polar, and under the principle of ‘like dissolves like’ this will allow for the proper extraction of trimyristin from the nutmeg.
What is the triglyceride extracted from nutmeg?
This is the type of extraction we performed in our experiment. Nature of the Experiment. Our goal was to extract a triglyceride called trimyristin from solid nutmeg. Nutmeg is a spice from the ground-up seed of the East Indian nutmeg tree. Plant seeds are typically rich in triglycerides, the fatty acid triesters of glycerol.
How much trimyristin is in 5g of dried nutmeg?
In 5g of dried nutmeg with 20-25% composed of trimyristin the theoretical yield after the extraction should be between 1.00g and 1.25g of trimyristin.
