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what is the most effective antiemetic

by Miss Eldridge McKenzie III Published 3 years ago Updated 2 years ago
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Which antiemetic drugs are most effective?

  • Chemotherapy. Many people require a combination of antiemetic drugs for CINV. ...
  • Viral or bacterial infections of the digestive tract. The most effective options for this situation are usually dopamine receptor antagonists and serotonin receptor antagonists.
  • Motion sickness or ear infections. ...
  • Pregnancy. ...
  • Migraines. ...

A systematic review found that serotonin antagonists (ondansetron, granisetron and tropisetron), dexamethasone, droperidol and cyclizine were all more effective than placebo for the treatment of postoperative nausea and vomiting.Apr 1, 2020

Full Answer

What are antiemetic drugs used to treat?

Antiemetic drugs are taken to treat nausea and vomiting, and can be administered as tablets, sublinguals, oral solutions, suppositories, transdermal patches or intravenous injections. Nausea and vomiting can be symptoms of various conditions, such as motion sickness, upper abdominal irritation, food poisoning, and gastroenteritis.

What is an antiemetic for nausea?

Medicines for nausea are called antiemetics. They can help relieve nausea and vomiting. Several OTC medicines are used as antiemetics. These include: Bismuth subsalicylate (2 brand names: Kaopectate, Pepto-Bismol). It may help treat some types of nausea and vomiting,...

How should I take antiemetic drugs?

Some antiemetic drugs are taken by mouth. Others are available as an injection or as a patch placed on your body so you don’t have to swallow anything. The type of antiemetic drug you should take depends on what is causing your symptoms: Antihistamines that prevent nausea and vomiting caused by motion sickness are available over the counter (OTC).

What is the best anti-antiemetics for chemotherapy?

Antiemetics for chemotherapy. Some prescription treatments include: serotonin 5-HT3 receptor antagonists: dolasetron (Anzemet), granisetron (Kytril, Sancuso), ondansetron (Zofran, Zuplenz), palonosetron (Aloxi) dopamine antagonists: prochlorperazine (Compazine), domperidone (Motilium, not available in the US),...

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What is the best anti vomiting drug?

Best anti-nausea medicationsBest anti-nausea medicationsZofran (ondansetron)RxGet CouponPromethegan (promethazine)RxGet CouponPhenergan (promethazine)RxGet CouponReglan (metoclopramide)RxGet Coupon10 more rows

What is the most effective OTC antiemetic?

Bismuth subsalicylate (Kapectate, Pepto-Bismol). It is best for nausea brought on by the stomach flu or food poisoning. It works by reducing inflammation, slowing down the flow of fluids to the intestines, and potentially killing bacteria that may cause stomach upset.

Which is most effective against nausea and vomiting?

Bismuth subsalicylate(2 brand names: Kaopectate, Pepto-Bismol). This medicine may help treat some types of nausea and vomiting, such as from gastroenteritis (stomach flu). It's also used for upset stomach and as an antidiarrheal (medicine to treat diarrhea). Antihistamines.

What is the most common antiemetic?

The most well-known natural antiemetic is ginger (Zingiber officinale). Ginger contains 5-HT3 antagonists known as gingerols. Clinical studies show that ginger may be effective in treating nausea and vomiting.

How can I stop vomiting immediately?

What can be done to control or relieve nausea and vomiting?Drink clear or ice-cold drinks.Eat light, bland foods (such as saltine crackers or plain bread).Avoid fried, greasy, or sweet foods.Eat slowly and eat smaller, more frequent meals.Do not mix hot and cold foods.Drink beverages slowly.More items...•

What is equivalent to Zofran over-the-counter?

Dramamine is used for prevention and treatment of symptoms associated with motion sickness including nausea, vomiting, and dizziness. Brand names for ondansetron include Zofran, Zofran ODT, and Zuplenz. Dramamine is a brand name for dimenhydrinate. Dramamine is available over-the-counter (OTC).

What are 7 drug classes of antiemetics?

Antiemetic drugs are medicines that ease nausea or vomiting....Antiemetics that a doctor may prescribe after surgery include:dexamethasone (Decadron)droperidol (Inapsine)granisetron (Kytril)metoclopramide (Reglan)ondansetron (Zofran)

Why can't you take Zofran OTC?

Ondansetron is a prescription medication, which means you can't get it over the counter. It must be prescribed by a healthcare professional.

Does Cyclizine work straight away?

Cyclizine starts to work after 30 minutes. You should feel better after 1 to 2 hours. It should work for about 4 to 6 hours.

What's better Zofran or Phenergan?

Phenergan has an average rating of 7.2 out of 10 from a total of 135 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 24% reported a negative effect. Zofran has an average rating of 8.0 out of 10 from a total of 212 ratings on Drugs.com.

Which is better for nausea Zofran or promethazine?

Conclusions: Promethazine and ondansetron have similar efficacy in reducing nausea among ED patients. Change in anxiety was similar, but promethazine was associated with greater sedation.

Which is better ondansetron or prochlorperazine?

These results demonstrate that prochlorperazine and ondansetron appear to be equally effective at controlling vomiting in patients presenting to the ED with nausea and/or vomiting. Theoretically prochlorperazine may have an advantage over ondansetron, as serotonin can cause the release of dopamine.

What are antiemetic drugs?

Antiemetic drugs are medications used to treat nausea and vomiting. These two symptoms are very common and can be caused by many different conditio...

What does antiemetic mean?

Antiemetic literally means ‘against emesis’, otherwise known as against vomiting.

How do antiemetics work?

Antiemetics work on the neural pathways involved with vomiting by blocking specific receptors that respond to neurotransmitter molecules, such as s...

What are the side effects of antiemetic drugs?

Antiemetics are generally well-tolerated, but can have potential side effects, such as constipation or diarrhea, headache, fatigue, malaise, dizzin...

What are antiemetic drugs used for?

Antiemetic drugs are taken to treat nausea and vomiting, and can be administered as tablets, sublinguals, oral solutions, suppositories, transderma...

What are some examples of antiemetics?

There are a few classes of antiemetic medications, which are categorized based on the predominant receptor they act on. Choosing the most appropria...

What is the most effective antiemetic?

Out of all medications indicated for vomiting, it’s difficult to choose the most effective one. The medication should be appropriately chosen by a...

Which antiemetic is indicated for use with vertigo?

Vertigo is an illusion of motion often accompanied by headaches, nausea, and vomiting. Most often, H1 receptor antagonists from the antihistamines...

What are the most important facts to know about antiemetics?

Antiemetics are medications aimed at preventing or treating nausea and vomiting, which are common symptoms that may be tied to numerous different c...

What antiemetics are prescribed after chemo?

Different types of drugs can help, including serotonin and dopamine receptor blockers, NK1 receptor blockers, and corticosteroids. Some antiemetics that people take to combat nausea from chemotherapy include:

Why are antihistamines important?

The inner ear plays an important role in balance, and it is sensitive to the movements caused by sitting in a moving car or a boat, for example. Antihistamines that combat nausea caused by motion sickness include: Each can cause side effects, and it is important to speak with a doctor before trying one.

What is an antiemetic drug?

Side effects. Complications. Natural antiemetics. Summary. Antiemetic drugs are medicines that ease nausea or vomiting. A person might use an over-the-counter or prescription version. The feeling of nausea results from a complex process in the body, and this is why various drugs have been designed to ease nausea in different situations.

What antiemetics are safe for pregnancy?

Some antiemetics for morning sickness include: dimenhydrinate (Dramamine, Gravol) prochlorperazine (Compazine) promethazine. vitamin B6.

How does surgery affect the brain?

These medications work by blocking chemical messengers called neurotransmitters, which send information about nausea to the brain. Blocking their signals can keep a person from feeling nauseous and vomiting.

What are the effects of corticosteroids?

cannabinoids: an altered state of perception and dizziness. corticosteroids: indigestion, increased appetite or thirst, and acne. dopamine receptor blockers: fatigue, constipation, ringing in the ears, dry mouth, restlessness, and muscle spasms. NK1 receptor blockers: dry mouth, reduced urine volume, and heartburn.

What is the best medicine for nausea?

Natural antiemetics. Some natural options exist for people who prefer to avoid drugs. Ginger is a traditional remedy for nausea and an upset stomach. The findings of a review from 2015, for example, confirm its effectiveness, though the researchers highlight the need for more research.

What is the treatment for nausea and vomiting after chemo?

Antiemetics for chemotherapy. Nausea and vomiting are a common part of chemotherapy treatment. Antiemetic drugs are used before and after chemotherapy to prevent symptoms. Some prescription treatments include:

Why do you take antiemetic drugs?

Antiemetic drugs are prescribed to help with nausea and vomiting that are side effects of other drugs. This may include drugs for anesthesia used during surgeries or chemotherapy for cancer. Antiemetic drugs are also used for nausea and vomiting caused by: motion sickness. morning sickness during pregnancy.

What is the medication for postoperative nausea?

Prescription drugs used for treating PONV include: dopamine antagonists: metoclopramide (Reglan), droperidol (Inapsine), domperidone.

What is the best medication for motion sickness?

Antiemetics for motion sickness. Antihistamines that prevent nausea and vomiting caused by motion sickness are available over the counter (OTC). They work by keeping your inner ear from fully sensing motion and include: dimenhydrinate (Dramamine, Gravol) meclizine (Dramamine Less Drowsy, Bonine)

What are the side effects of antiemetic drugs?

The side effects depend on the type of antiemetic drug you take: dopamine antagonists: dry mouth, fatigue, constipation, tinnitus, muscle spasms, restlessness. If you experience any of the following, consult your doctor:

What is the best medicine for nausea?

Make sure you read the labels carefully or follow your doctor’s instructions. For mild cases of nausea or vomiting, try an herbal therapy like ginger.

How to get rid of nausea and vomiting?

Clinical studies show that ginger may be effective in treating nausea and vomiting. Steep fresh ginger in hot water to make tea, or try candied ginger, ginger biscuits, or ginger ale. way to overcome nausea and vomiting. Try rubbing a couple drops into the back of your neck and taking deep breaths.

What is Bismuth subsalicylate used for?

Bismuth subsalicylate (2 brand names: Kaopectate, Pepto-Bismol). This medicine may help treat some types of nausea and vomiting, such as from gastroenteritis (stomach flu). It’s also used for upset stomach and as an antidiarrheal (medicine to treat diarrhea). Antihistamines.

What is the OTC medicine for nausea?

Antiemetic Medicines: OTC Relief for Nausea and Vomiting. Over-the-counter (OTC) medicines are medicines you can buy without a prescription from your doctor. Medicines that treat nausea and vomiting are called antiemetics. Several OTC medicines are used as antiemetics. These include: Bismuth subsalicylate (2 brand names: Kaopectate, Pepto-Bismol).

Why do antihistamines work?

Antihistamines appear to dull the inner ear’s ability to sense motion. They block messages to the part of the brain that controls nausea and vomiting. This is why they work best if you take them before you start feeling motion sickness.

How to make sure you are taking the right amount of medicine?

Follow these tips to make sure you are taking the right amount of medicine: Take only the amount recommended on the medicine’s label. Don’t assume that more medicine will work better or quicker. Taking more than the recommended amount can be dangerous.

Can you take bismuth with aspirin?

Ask your doctor before taking bismuth subsalicylate if you take pain relievers or cold medicines. These medicines may contain aspirin, which is a salicylate. You may get too much salicylate if you take more than 1 of these medicines at a time.

Can you take more than one antihistamine?

If you use more than 1 of these medicines, you may get more antihistamine than you intend. Some prescription medicines have side effects similar to the side effects of antihistamines. These could include dry mouth and drowsiness. Talk with your doctor before taking these medicines at the same time.

What is an antiemetic?

As a noun, a drug taken to prevent or treat nausea and vomiting. As, for example, the antihistamine meclizine hydrochloride (Bonine). As an adjective, pertaining to the prevention or treatment of nausea and vomiting. Opening a window in a car can have an antiemetic effect. Read more about antiemetics definition ».

Why is emetrol used for nausea?

Emetrol is an oral solution designed to soothe the stomach when nausea and vomiting are caused by viral or bacterial infection or overeating. Emetrol contains sugar and phosphoric acid. Diabetics should not use Emetrol without medical supervision because of the concentrated sugar.

What is the medication used to treat nausea and vomiting?

Drugs used to treat nausea and vomiting are called antiemetics. Many types of antiemetics can decrease the severity of nausea. Nausea and vomiting occur for many reasons. Common causes include motion sickness, self-limited illnesses ( viruses or food poisoning) that last a few hours to a few days, and toxins (such as certain medications).

What are the symptoms of vomiting and nausea?

People should consult a doctor if nausea and/or vomiting are persistent or are accompanied by other severe symptoms such as abdominal pain, fever, yellow discoloration of the skin ( jaundice ), or bleeding.

What percentage of pregnant women have nausea?

early stages of pregnancy (nausea occurs in approximately 50%-90% of all pregnancies, vomiting in 25%-55%), painful injury, postoperative (the period following surgery), an emotional or fearful situation, gallbladder disease, gallstones or infection ( cholecystitis ), overeating (especially after gastric bypass surgery ),

Can you use bismuth subsalicylate on pregnant women?

Pregnant or nursing women should consult their doctors before using bismuth subsalicylate since part of the active ingredient (salicylate) is chemically similar to aspirin, which may harm infants and the fetus. Patients allergic to aspirin or related drugs also should not use bismuth subsalicylate.

What are the symptoms of gallbladder disease?

gallbladder disease, gallstones or infection ( cholecystitis ), overeating (especially after gastric bypass surgery ), a reaction to certain smells or odors, heart attack (may be the only symptom in some people), concussion or head injury, brain tumor, ulcers or gastritis,

Which regimens are more effective in producing CR?

Further analysis, based on the surface under the cumulative ranking probability curve, indicated that olanzapine-containing regimens were the most effective in producing CR.

Is olanzapine effective for aprepitant?

Furthermore, the 70% less costly drug, olanzapine, is suggested to be equally effective to aprepitant in reducing nausea and vomiting. The possibility of offering a cost-effective treatment to a wider range of the population is discussed.

Can chemotherapy cause nausea?

Nausea and vomiting during chemotherapy often pose difficulties for patients and doctors, making it hard to continue the proper therapy and to maintain the quality of life. This article gives insights into the optimal choice of medicine to treat nausea during chemotherapy.

What Are Prescription Antiemetics?

Prescription antiemetic drugs are grouped by how they work in the body. Some groups of prescription anti-nausea drugs work better for certain conditions. Some medications combine two types of these medications to effectively treat different causes of nausea at one time.

Are Antiemetics Safe?

Follow directions on the medicine’s package and any directions given to you by your doctor. Some people think that taking more will make the medicine work better or faster; however, taking more than recommended can be harmful.

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1.Antiemetics: What Are They, How Do They Work, What …

Url:https://www.osmosis.org/answers/antiemetics

2 hours ago Dopamine antagonists, such as metoclopramide ( Reglan ), domperidone (Motilium), and chlorpromazine, are amongst the most commonly used antiemetics, and they’re also indicated for postoperative nausea and motion sickness . H1 antihistamines, such as cyclizine, promethazine, and diphenhydramine, or antimuscarinics ( anticholinergics) like scopolamine ( Hyoscine) are …

2.Antiemetic drugs list: Types and side effects - Medical …

Url:https://www.medicalnewstoday.com/articles/320384

10 hours ago  · Which antiemetic drugs are most effective? Chemotherapy. Many people require a combination of antiemetic drugs for CINV. However, the risk of nausea and vomiting... Viral or bacterial infections of the digestive tract. The most effective options for this situation are usually dopamine... Motion ...

3.What Are Antiemetic Drugs, and What Are the Best …

Url:https://www.goodrx.com/classes/antiemetics/antiemetic-drugs

21 hours ago  · “What is the most effective antiemetic in the ER setting?”: – For nausea and vomiting in the ER setting, metoclopramide, prochlorperazine, and promethazine were shown to be no more effective than placebo. These agents also comes with a risk of akathisia- especially if given as an IV bolus

4.Antiemetic Drugs List: OTC, Side Effects, for Pregnancy, …

Url:https://www.healthline.com/health/antiemetic-drugs-list

33 hours ago  · Meclizine hydrochloride is an antihistamine that is effective in the treatment of nausea, vomiting, and dizziness associated with motion sickness. Unless recommended by a physician, it should not be taken by people with lung diseases, glaucoma , or those who have difficulty urinating due to an enlarged prostate .

5.Antiemetic Medicines: OTC Relief for Nausea and Vomiting

Url:https://familydoctor.org/antiemetic-medicines-otc-relief-for-nausea-and-vomiting/

14 hours ago We confirmed that NK1RA + PAL + Dex is the most effective of conventional regimens. Substituting olanzapine for an Nk-1 receptor antagonist may offer a less costly and more effective alternative for patients.

6.Antiemetics for Nausea and Vomiting: Types and Side …

Url:https://www.medicinenet.com/antiemetics/article.htm

16 hours ago  · What is considered the most effective AE? Suicide Discussion Quick Exit Suicide Discussion Recovery OffTopic News ... Forums. New posts What's new. Rules & Info. Tickets. Open new ticket. Light/Dark Most effective antiemetic Thread starter Neuro; Start date 3 minutes ago . Forums. Sanctioned Suicide. Suicide Discussion. N. Neuro Member. Jun 12 ...

7.Effectiveness of Antiemetic Regimens for Highly …

Url:https://pubmed.ncbi.nlm.nih.gov/30333194/

13 hours ago What Are OTC Antiemetics? There are two types of over-the-counter antiemetics: Bismuth subsalicylate (Kapectate, Pepto-Bismol). This medication treats vomiting, nausea, and diarrhea.

8.What to Know About Antiemetics for Nausea - WebMD

Url:https://www.webmd.com/digestive-disorders/what-to-know-about-antiemetics-for-nausea

20 hours ago

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