Is CC genotype A Sickler? Hemoglobin C disease is not a form of sickle cell disease. People who have hemoglobin C disease have red blood cells that contain mostly hemoglobin C. Too much hemoglobin C can reduce the number and size of red blood cells in your body causing mild anemia.
What is the phenotype of an individual?
Phenotype A phenotype is an individual's observable traits, such as height, eye color, and blood type. The genetic contribution to the phenotype is called the genotype.
What is the genetic contribution to the phenotype called?
The genetic contribution to the phenotype is called the genotype. Some traits are largely determined by the genotype, while other traits are largely determined by environmental factors. "Phenotype" simply refers to an observable trait. "Pheno" simply means "observe" and comes from the same root as the word "phenomenon".
What is the Cold phenotype?
As the name suggests, the ‘cold phenotype’ is a panel that determines the expression of all antigens with common corresponding cold-reacting antibodies (M, N, P, Lea and Leb).
What is a complete phenotype in immunology?
A complete phenotype is performed when the patient has multiple antibodies that are both cold-reacting and warm-reacting. This determines the patient’s antigen profile for K, E, e, C, c, Fya, Fyb, Jka, Jkb, S, s, M, N, Lea and Leb antigens.
Is CC genotype or phenotype?
GenotypewphenotypeSS0.2anemiaAC0.9malarial susceptibilitySC0.7anemiaCC1.3malarial resistance2 more rows
What is the phenotype of the rabbit with the genotype CC?
If your rabbit is albino (white coat and red eyes), then the genotype is cc. You will not be able to identify any of the other genotypes based off of the phenotype.
What is the phenotype of DD?
dimplesSusan's genotype is "Dd", so she is considered HETEROZYGOUS (has two different alleles for a specific gene). Although Susan has both the allele "D" to make dimples and the allele "d" in her genotype, her phenotype is the presence of dimples....TttTt (tall)tt (short)1 more row
Is CC genotype dominant or recessive?
Incomplete Dominance Curly hair type (CC) is dominant to straight hair type (cc). An individual who is heterozygous for this trait will have wavy hair (Cc). In incomplete dominance relationships, one allele for a specific trait is not completely dominant over the other allele.
What is the phenotype of YY?
yellow seed colorYy is the heterozygous genotype (one dominant allele, one recessive allele). The phenotype of this genotype is yellow seed color. yy is the homozygous dominant genotype (2 y alleles). The phenotype of this genotype is green seed color.
What is example of phenotype?
Examples of phenotypes include height, wing length, and hair color. Phenotypes also include observable characteristics that can be measured in the laboratory, such as levels of hormones or blood cells.
What is the phenotype of TT?
tallThe phenotype of a plant with the genotype Tt would be tall. Here tallness (T) is a dominant trait over dwarfness (t), which is recessive. Tallness and dwarfness (stem height) are one of the seven contrasting pairs of traits in pea plants studied by Mendel.
Is CC a heterozygous or homozygous?
All of the above results have involved comparisons of the heterozygote (Cc) with the homozygous recessive genotype (cc).
What is the genotype for BB?
An organism with two dominant alleles for a trait is said to have a homozygous dominant genotype. Using the eye color example, this genotype is written BB.
What is CC genotype?
Hemoglobin C Disease. If a person inherits a gene for Hemoglobin C from both parents (CC), that person will have Hemoglobin C disease. This disease may produce mild to moderate anemia, jaundice, enlarged spleen and gallstones.
How do you determine phenotype?
To find a phenotypic ratio, we look at the alleles of the parent organisms and estimate how often those genes will be exhibited by the offspring. Most times, we know what the alleles will express and how they will look.
What is my phenotype?
Phenotype Definition Phenotype is a description of your physical characteristics. It includes both your visible traits (like hair or eye color) and your measurable traits (like height or weight). Phenotype also refers to characteristics related to your development and behavior, like elements of your personality.
What is C gene in rabbits?
Finally, the most recessive gene, the "c" gene takes all the color from the rabbit's coat, leaving all white fur, no matter the other gene pairs in the rabbit. Both the "ch" gene and the "c" gene removes color pigment from the eyes as well as the fur. When color is taken from the eyes, the eyes appear red.
What allele is dominant over C ch?
The C allele is dominant over all others, cch is dominant over ch and c, ch is dominant over c, and c is recessive to all other alleles. This dominance hierarchy can be summarized as C > cch > ch > c.
What is the phenotype of a heterozygous rabbit?
Two heterozygous white (brown fur is recessive) rabbits are crossed. The parents' genotypes are BB and Bb. The offspring's genotypes are 50% BB, 50% Bb, which means their phenotypes are 100% brown.
What is the genotype of the rabbit with white fur?
Directions: In rabbits, gray hair (G) is dominant to white hair (g), and black eyes (B) are dominant to red eyes (b). These two traits are independent of each other. In other words, a female rabbit with the genotype GgBb may produce eggs with the alleles GB, Gb, gB, or gb.
How many genotypes can Aa produce?
Aa x Aa can produce three genotypes: AA, Aa and aa (Aa and aA are equivalent). The same with Bb x Bb and Cc x Cc. Since we presume they are independent, you have 3 x 3 x 3 = 27 combinations (AABBCC, AABBCc, AABBcc, AABbCC, AABbCc, AABbcc … aabbcc). The proportions of them are a different matter, though (for instance, AABBCC are 1/64 and AaBbCc are 1/8).
How to find a plant that is homozygous recessive?
Work out all the possible genotypes of plant that could be 'tall' (there are only two) then use a Punett square to cross each of these in turn with a plant that is homozygous recessive ( phenotypically dwarf).
What is test cross?
Test cross is one type of ‘back cross’ in which the f1 generation progeny is crossed with it's recessive parent .
What is the cold phenotype?
As the name suggests, the ‘cold phenotype’ is a panel that determines the expression of all antigens with common corresponding cold-reacting antibodies (M, N, P, Lea and Leb ). The ‘full warm phenotype’ is a panel that determines the expression of all the antigens with common clinically significant corresponding antibodies that are warm reacting (K, E, e, C, c, Fya, Fyb, Jka, Jkb, S and s). The ‘complete phenotype’ is a panel that determines the expression of all antigens with common corresponding antibodies, either warm reacting (K, E, e, C, c, Fya, Fyb, Jka, Jkb, S and s) or cold reacting (M, N, P, Lea and Leb). In some cases, a ‘limited phenotype’ panel is performed to detect one or a few specific antigens. RBC phenotyping is always performed from a pre-transfusion specimen to avoid interference from transfused red blood cells. 2-3
When is a full warm phenotype performed?
A full warm phenotype is performed prior to drug administration to allow phenotype matched transfusions during the period the medication is administered when new antibodies cannot be detected and thus allow safe transfusions. 1.2 Indication to perform a red blood cell antigen cold phenotype.
What is the purpose of a limited antigen phenotype?
If an antibody panel identifies one or several alloantibodies of unclear specificity, performing a limited antigen phenotype may help determine the specificity of the antibody (ies).
Why do you perform RBC antigen phenotyping?
Performing RBC antigen phenotyping after identifying alloantibodies is critical to provide best matched transfusions and prevent additional antibodies from forming. This is performed either by a full warm phenotype or limited phenotype based on the reflex testing pathway.
Why do you need a warm phenotype before a transfusion?
Thus, performing a full warm phenotype prior to transfusions allows the transfusion services laboratory to provide fully or partially phenotype-matched units for these patients to prevent development of alloantibody (ies). The clinical indication for a full warm RBC phenotype prior to transfusions are as follows-
What is extended phenotyping?
That is, extended phenotyping usually supplements routine pre-transfusion testing in patients with clinically relevant alloantibody (ies) or in patients who are at risk for making clinically relevant alloantibody (ies).
How to determine the expression of red blood cells?
As the name suggests, red blood cell antigen expression may also be determined using genetic testing. Current testing allows the patient’s genomic DNA to be isolated and red cell antigen genotyping performed to predict the red cell antigen phenotype for select antigens. This is a send-out test, currently performed at Versiti laboratories. There are two panels available - Red cell genotyping panel (44 antigens) and a STAT panel (24 antigens). 4
