Precautions
Food and Drug Administration (FDA) list the following types of ACE inhibitor:
- benazepril (Lotensin)
- captopril
- enalapril (Vasotec)
- enalaprilat
- fosinopril
- lisinopril (Zestril and Prinivil)
- moexipril
- perindopril
- quinapril (Accupril)
- ramipril (Altace)
What are some names of ACE inhibitors?
What is the safest ACE inhibitor? For all-cause mortality, ramipril was associated with the lowest mortality and lisinopril with the highest. For increasing ejection fraction and stroke volume, enalapril was the most effective and the placebo ranked the lowest in efficacy. ... angiotensin-converting enzyme (ACE) inhibitors, works best when ...
What is the safest ACE inhibitor?
The following is a list of the ACE inhibitors that are available in the United States:
- benazepril(Lotensin, LotensinHct),
- captopril(Capoten),
- enalapril (Vasotec),
- fosinopril(Monopril),
- lisinopril(Prinivil, Zestril),
- moexipril (Univasc)
- perindopril(Aceon),
- quinapril(Accupril),
What are the most common ACE inhibitors?
- Thiazide diuretics.
- Calcium channel blockers - CCBs.
- Angiotensin-converting enzyme inhibitors -ACEIs.
- Angiotensin receptor blockers - ARBs.
What is the best ACE inhibitor?
See more
What is the generic suffix associated with the ACE inhibitor class?
ACE inhibitors have the common suffix –pril. Examples include captopril, ramipril and perindopril.
What suffix do beta blockers end in?
A few examples of drug stems are: ▪ -olol: a suffix for beta blockers which include atenolol, bisoprolol, esmolol, metoprolol, and propranolol.
What is suffix pril?
A suffix used in pharmacology to designate an angiotensin-converting-enzyme (ACE) inhibitor.
Which drugs are ACE inhibitors?
Angiotensin-converting enzyme inhibitor (ACE inhibitors) drugs include Benazepril (Lotensin), Captopril (Capoten), Enalapril/Enalaprilat (Vasotec oral and injectable), Fosinopril (Monopril), Lisinopril (Zestril and Prinivil), Moexipril (Univasc), Perindopril (Aceon), Quinapril (Accupril), Ramipril (Altace), and ...
How do you break down medication names?
Usually, drugs of the same therapeutic class are given names with the same stem. These stems are mostly placed word-finally (suffix), but in some cases, word-initial (prefix) stems are also used. Stems are useful for making communication of drugs more precise to avoid prescribing errors.
What drugs end in Pam?
“-Pam” and “-Lam” are usually the two suffixes of benzodiazepines with medications like:Lorazepam (Ativan)Alprazolam (Xanax)Clonazepam (Klonopin)Diazepam (Valium)
What medications end in the suffix sartan?
Angiotensin receptor blockers are a class of medicines that is used to treat high blood pressure (also known as hypertension). These medicines have names that end in 'sartan', including valsartan, irbesartan, candesartan, losartan and olmesartan.
What do ACE inhibitors do?
Angiotensin-converting enzyme (ACE) inhibitors are medications that help relax the veins and arteries to lower blood pressure. ACE inhibitors prevent an enzyme in the body from producing angiotensin II, a substance that narrows blood vessels.
Why do beta blockers end in Olol?
According to the FDA, identification of these types of drugs must be through their suffix. One of the easiest ways to identify your beta-blockers is to know, by heart, that it can make you laugh out loud (LOL). Meaning, beta-blockers generic names end in –lol. A typical example is atenolol and metoprolol.
What is the best ACE inhibitor?
Lisinopril (Zestril), enalapril (Vasotec), and benazepril (Lotensin) are popular options.
What does ACE stand for in ACE inhibitor?
ACE inhibitors can reduce the activity of an enzyme called angiotensin-converting enzyme, or ACE for short. The enzyme is responsible for hormones that help control your blood pressure. It has a powerful narrowing effect on your blood vessels, which increases your blood pressure.
Is aspirin an ACE inhibitor?
Aspirin blocks prostaglandin production, whereas ACE inhibitors tend to increase it. Animal experiments have shown that aspirin can block ACE inhibitor–induced vascular relaxation. Studies have also suggested that the combination of aspirin and ACE inhibitors may have an adverse effect on renal function.
Why do beta-blockers end in Olol?
According to the FDA, identification of these types of drugs must be through their suffix. One of the easiest ways to identify your beta-blockers is to know, by heart, that it can make you laugh out loud (LOL). Meaning, beta-blockers generic names end in –lol. A typical example is atenolol and metoprolol.
What word stem indicates that a medication is a beta blocker?
For example, drugs ending in the stem -olol belong to the class of drugs known as beta blockers. Some examples of beta blockers available in the US include atenolol, bisoprolol, esmolol, metoprolol, and propranolol.
What is beta blocker?
Beta blockers, also known as beta-adrenergic blocking agents, are medications that reduce blood pressure. Beta blockers work by blocking the effects of the hormone epinephrine, also known as adrenaline. Beta blockers cause the heart to beat more slowly and with less force, which lowers blood pressure.
What is a suffix in medical terminology?
The suffix usually indicates a specialty, test, procedure, function, condition/disorder, or status. For example, “itis” means inflammation and “ectomy” means removal. Alternatively, the suffix may simply make the word a noun or adjective.
What is a drug prefix, root, and suffix?
A root is the core of a word, usually located in the middle of a word, that specifies its meaning. Prefixes and/or suffixes are added to the root t...
What is the drug suffix for beta-blockers?
The suffix for beta-blockers is -lol, often -olol although sometimes -alol is also used.Examples: atenolol, metoprolol, propranololAction: Reduce b...
What is the drug suffix for ACE inhibitors?
The suffix for ACE inhibitors is -pril.Examples: captopril, lisinoprilAction: Reduce blood pressure by dilating blood vessels, thus reducing the he...
What is the drug suffix for calcium channel blockers?
The suffix for calcium channel blockers is -dipine.Examples: amlodipine, nifedipineAction: Relax blood vessels, therefore increasing blood supply a...
What is the drug suffix for angiotensin-II receptor blockers?
The suffix for angiotensin-II receptor blockers (ARBs) is -sartan.Examples: losartan, valsartanAction: Inhibit blood vessel constriction, helping b...
What are the drug suffixes for the different types of diuretics?
The suffix for potassium-sparing diuretics is -actone.Examples: spironolactone, aldactoneAction: Increase the fluid excreted by the kidneys, while...
What is the drug suffix for cholesterol-lowering drugs?
The suffix for anti-lipids is -statin.Examples: atorvastatin, simvastatinAction: Reduce LDL cholesterol and lower risks from cardiovascular disease.
What are the drug suffixes for the different types of antibiotics?
The suffix for tetracyclines is -cycline.Examples: doxycyclineAction: Broad spectrum antibiotic that treats bacterial infections.The suffix for ami...
What is the drug suffix for antiviral medications?
The suffix for antiviral medications is -vir.Examples: acyclovirAction: Protect the body against, or fight current, viral infections through variou...
What is the drug suffix for antiemetics?
The suffix for antiemetics is -azine.Examples: promethazineAction: Treat and prevent nausea and vomiting.
What are some examples of ACE inhibitors?
Examples of ACE inhibitors include: Benazepril (Lotensin) Captopril. Enalapril (Vasotec)
How does ACE inhibitor work?
ACE inhibitors prevent an enzyme in your body from producing angiotensin II, a substance that narrows your blood vessels.
Can you take ACE inhibitors while pregnant?
Taking ACE inhibitors during pregnancy increases the risk of birth defects in the baby. If you're pregnant or plan to become pregnant, talk to your doctor about other options to treat high blood pressure.
Can ACE cause angioedema?
Rarely, ACE inhibitors can cause some areas of the tissues to swell (angioedema). If swelling occurs in the throat, it can be life-threatening.
Can you take ACE inhibitors with angiotensin blocker?
ACE inhibitors shouldn't be taken with an angiotensin receptor blocker or with a direct renin inhibitor. ACE inhibitors work better for younger people than for older people. They also work better for white people than for black people. Your doctor may recommend a different medication.
Why is ACE inhibitors used?
The use of a maximum dose of ACE inhibitors in such patients (including for prevention of diabetic nephropathy, congestive heart failure, and prophylaxis of cardiovascular events) is justified, because it improves clinical outcomes independently of the blood pressure-lowering effect of ACE inhibitors.
What are the side effects of ACE inhibitor?
Adverse effects. Common side effects include: low blood pressure, cough, hyperkalemia, headache, dizziness, fatigue, nausea, and kidney impairment. The main adverse effects of ACE inhibition can be understood from their pharmacological action. The other reported adverse effects are liver problems and effect on the fetus.
What is acei used for?
Angiotensin-converting-enzyme inhibitors ( ACE inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure.
What are the consequences of taking potassium with ACE inhibitors?
This leads to cardiac dysfunction and neuromuscular consequences, such as muscle weakness, paresthesia, nausea, diarrhea, and others. Close monitoring of potassium levels is required in patients receiving treatment with ACE inhibitors who are at risk of hyperkalemia.
What are the symptoms of an overdose on ACE inhibitors?
Symptoms and Treatment: There are few reports of ACE inhibitor overdose in the literature. The most likely manifestations are hypotension, which may be severe, hyperkalemia, hyponatremia and renal impairment with metabolic acidosis.
How long should renal function be monitored after ACE?
Therefore, renal function should be closely monitored over the first few days after initiation of treatment with ACE inhibitor in patients with decreased renal perfusion.
Which probiotics have antihypertensive and ACE inhibitors?
The lactotripeptides Val-Pro-Pro and Ile-Pro-Pro produced by the probiotic Lactobacillus helveticus or derived from casein have been shown to have ACE-inhibiting and antihypertensive functions. In one study, L. helveticus PR4 was isolated from Italian cheeses.
What end does ACE inhibitor end in?
ACE inhibitors end in -pril, such as captopril and lisinopril. ACE inhibitors reduce blood pressure by dilating blood vessels, thus reducing the heart’s workload. Beta-blockers end in -lol, such as atenolol, propranolol, and labetalol. Beta-blockers reduce blood pressure by slowing the heart rate and reducing myocardial contractility.
What is the drug ending and azine used for?
Drugs ending and -azine, such as promethazine, are an antiemetic used to treat nausea and vomiting.
What is the antibiotic ending with a virus?
Fluoroquinolones are a broadspectrum antibiotic ending with -floxacin, such as ciprofloxacin and levofloxacin. While antibiotics treat bacterial infections, antivirals treat a virus infection. If the ending is -vir, it’s most likely an antiviral, such as acyclovir.
What antibiotics have an easy ending?
There are tetracyclines, which have an easy ending -cycline, such as tetracycline or doxycycline. These broadspectrum anti-microbial drugs are used in treating and preventing bacterial infections. Aminoglycosides are another antibiotic ending with -mycin, such as neomycin and tobramycin.
What is the drug that ends in a lam?
Drugs ending in -pam or -lam are most likely a benzodiazepine, which are used to treat anxiety, and prolonged use may lead to physical dependence. Benzodiazepines include alprazolam (Xanax), diazepam (Valium), and lorazepam (Ativan).
What is the name of the medication that is used to treat anxiety?
Medications used to treat depression and anxiety include the following: Drugs ending in -pam or -lam are most likely a benzodiazepine, which are used to treat anxiety, and prolonged use may lead to physical dependence. Benzodiazepines include alprazolam (Xanax), diazepam (Valium), and lorazepam (Ativan).
What is the medication that ends with a -arin?
If the medication ends with -arin, it’s most likely an anticoagulant, such as heparin or warfarin. Anticoagulants prevent blood coagulation or prolong the clotting time. Now, let’s take a look at some antibiotics. There are tetracyclines, which have an easy ending -cycline, such as tetracycline or doxycycline.
What is ACE inhibitor?
ACE inhibitors are an important medicinal class in the treatment of a wide range of cardiovascular disease. As pharmacy technicians, you will handle this important drug class daily – working within the community or hospital pharmacy and patients to deliver these essential medicines to patients.
What are the side effects of ACE inhibitors?
Other side effects of ACE inhibitors include: 1 Elevated potassium levels (hyperkalemia) 2 Increased risk of renal failure 3 Hypotension – which is worst after the first dose
How does ACE inhibitor work?
By blocking the ACE enzyme, ACE inhibitors prevent these two hypertensive mechanisms and therefore work to reduce blood pressure. By preventing the release of aldosterone, water and sodium are not encouraged to remain in the body – again, having a hypotensive effect.
What are the indications for aceon?
The indications of a medicine refer to what it is used to treat. There are four primary indications of ACE inhibitors, including: Hypertension – reducing blood pressure and the risk of stroke and/or heart attacks. Chronic heart failure – to improve symptoms and prognosis.
Can ACE cause coughing?
One of the most prominent side effects of ACE inhibitors is their propensity to cause a persistent, dry cough . This can often prove troublesome for the patient. Clinicians may decide to change to another hypotensive drug – such as angiotensin-receptor blockers (examples of which include candesartan and losartan).
Can you take ACE inhibitors while pregnant?
ACE inhibitors are not safe in pregnancy and so should be avoided.
Is ACE a pril?
As pharmacy technicians, you will invariably come across many ACE inhibitors. They are important medicines – and are easily identified as they all contain the suffix – pril .
Overview
Ramipril is used to treat high blood pressure (hypertension).
May Treat: Hypertension · Cerebrovascular accident · Chronic heart failure · Chronic heart failure following myocardial infarction · Diabetic nephropathy and more
Brand Names: Altace
Drug Class: ACE Inhibitors
Availability: Prescription Required
Pregnancy: Do not use. This medication may be harmful to an unborn child.
May Treat: Hypertension · Cerebrovascular accident · Chronic heart failure · Chronic heart failure following myocardial infarction · Diabetic nephropathy and more
Brand Names: Altace
Drug Class: ACE Inhibitors
Availability: Prescription Required
Pregnancy: Do not use. This medication may be harmful to an unborn child.
Lactation: Consult a doctor before using
Driving: May cause drowsiness or dizziness. Use caution
- Do not take if pregnant contact your doctor
- Drink fluids and try to avoid getting too hot
- May make you dizzy. Use caution when driving.
- Do not take if pregnant contact your doctor
- Drink fluids and try to avoid getting too hot
- May make you dizzy. Use caution when driving.
- Be careful not to stand up too quickly
- Tell doctor if bothersome cough develops & persists
- Tell Dr. of slow pulse. Avoid potassium salt.
- Review all drugs you are taking with your doctor
- It is important to check blood pressure regularly.
Examples
Medical use
Adverse effects
Overdose
Contraindications and precautions
ACE inhibitors are easily identifiable by their common suffix, '-pril'. ACE inhibitors can be divided into three groups based on their molecular structure of the enzyme binding sites (sulfhydryl, phosphinyl, carboxyl) to the active center of ACE:
• Alacepril
• Captopril (trade name Capoten), the first ACE inhibitor.
Mechanism of action
ACE inhibitors were initially approved for the treatment of hypertension and can be used alone or in combination with other anti-hypertensive medications. Later, they were found useful for other cardiovascular and kidney diseases including:
• Acute myocardial infarction (heart attack)
• Heart failure (left ventricular systolic dysfunction)
Comparative information
Common side effects include: low blood pressure, cough, hyperkalemia, headache, dizziness, fatigue, nausea, and kidney impairment.
The main adverse effects of ACE inhibition can be understood from their pharmacological action. The other reported adverse effects are liver problems and effects on the fetus. Kidney problems may occur with all ACE inhibitors that directly follows from their mechanism of action. Patients …