
Precautions
Zylet Description. Zylet (loteprednol etabonate and tobramycin ophthalmic suspension) is a sterile, multiple dose topical anti-inflammatory corticosteroid and anti-infective combination for ophthalmic use. Both loteprednol etabonate and tobramycin are white to off-white powders.
What kind of drug is Zylet?
Zylet Description. Zylet (loteprednol etabonate and tobramycin ophthalmic suspension) is a sterile, multiple dose topical anti-inflammatory corticosteroid and anti-infective combination for ophthalmic use.
What is Zylet ophthalmic suspension?
Zylet eye drops contain a combination of loteprednol and tobramycin. Loteprednol is a steroid. It prevents the release of substances in the body that cause inflammation. Tobramycin is an antibiotic that fights bacteria. Zylet eye drops are used to treat eye inflammation caused by surgery, infection, allergies, and other conditions.
What are Zylet eye drops made of?
Zylet (loteprednol etabonate and tobramycin ophthalmic suspension) is a sterile, multiple dose topical anti-inflammatory corticosteroid and anti-infective combination for ophthalmic use. Both loteprednol etabonate and tobramycin are white to off-white powders.
What is the composition of the powder in Zylet?

What is Zylet prescribed for?
This medication is used to treat conditions involving swelling (inflammation) of the eyes and to treat or prevent bacterial eye infections. This product contains tobramycin, an antibiotic that works by stopping the growth of bacteria.
Is Zylet a steroid?
Zylet (loteprednol / tobramycin) is a steroid-antibiotic combination eye medication that works well to treat eye inflammation (swelling) and bacterial eye infections, but it's a brand medication only and can cause high eye pressure and eye injury if used for a long time.
How long does it take for Zylet to work?
It takes several days to work, and while that may not sound like a long time, when you are used to wearing contacts everyday, having to do eye drops for a week and wearing glasses gets annoying after 3 days.
What are the side effects of Zylet eye drops?
Common side effects of Zylet include stinging, burning, irritation, itching, discomfort, or redness of the eyes for 1 to 2 minutes when this medication is applied. Other side effects of Zylet include headache, sensitivity of the eyes to light, or blurred vision.
What is the cost of Zylet?
The cost for Zylet ophthalmic suspension (0.5%-0.3%) is around $320 for a supply of 5 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Is Zylet a prescription?
Zylet is a prescription medicine used to treat the symptoms of Ocular Inflammation.
What is the generic name for Zylet?
Generic Name & Formulations: Loteprednol etabonate 0.5% + tobramycin 0.3%, oph susp; contains benzalkonium chloride.
Can Zylet be used for ear infection?
Zylet (loteprednol and tobramycin) Ocuflox (ofloxacin) is effective for most common types of eye and ear infections. Make sure to follow your doctor's instructions exactly on how to use it. Treats certain eye inflammation and infections.
Is pink eye a bacterial infection?
Pink eye is commonly caused by a bacterial or viral infection, an allergic reaction, or — in babies — an incompletely opened tear duct. Though pink eye can be irritating, it rarely affects your vision. Treatments can help ease the discomfort of pink eye.
Is Tobradex the same as Zylet?
Peer-reviewed clinical results published in Current Medical Research and Opinion¹ show Zylet (loteprednol etabonate 0.5 % and tobramycin 0.3 % ophthalmic suspension) to be clinically equivalent to Tobradex (dexamethasone 0.1 % and tobramycin 0.3 % ophthalmic suspension) in decreasing the signs and symptoms of ocular ...
Can tobramycin raise eye pressure?
Loteprednol and tobramycin eye drops is not for long-term use. Steroid eye drops may cause glaucoma (increased pressure inside the eye) or posterior subcapsular cataracts (a rare type of cataract) if used too long. Slow or delayed healing may also occur while you are using this medicine after cataract surgery.
What is tobramycin used for?
Ophthalmic tobramycin is used in the eye to treat bacterial infections of the eye. Tobramycin works by killing bacteria. Ophthalmic tobramycin may be used alone or with other medicines for eye infections. Either the drops or the ointment form of this medicine may be used alone during the day.
Is ciprofloxacin eye drops a steroid?
Ciprofloxacin belongs to a group of medicines called fluoroquinolone antibiotics. It works by killing bacteria that cause conjunctivitis. This medicine is available only with your doctor's prescription.
Is Tobradex the same as Zylet?
Peer-reviewed clinical results published in Current Medical Research and Opinion¹ show Zylet (loteprednol etabonate 0.5 % and tobramycin 0.3 % ophthalmic suspension) to be clinically equivalent to Tobradex (dexamethasone 0.1 % and tobramycin 0.3 % ophthalmic suspension) in decreasing the signs and symptoms of ocular ...
Can Zylet be used for ear infection?
Zylet (loteprednol and tobramycin) Ocuflox (ofloxacin) is effective for most common types of eye and ear infections. Make sure to follow your doctor's instructions exactly on how to use it. Treats certain eye inflammation and infections.
Can tobramycin raise eye pressure?
Loteprednol and tobramycin eye drops is not for long-term use. Steroid eye drops may cause glaucoma (increased pressure inside the eye) or posterior subcapsular cataracts (a rare type of cataract) if used too long. Slow or delayed healing may also occur while you are using this medicine after cataract surgery.
Is there a generic for Zylet (loteprednol / tobramycin)?
Currently, there is no generic form of Zylet (loteprednol / tobramycin). If you're having trouble paying for it, talk to your provider to see if yo...
How long should Zylet (loteprednol / tobramycin) be used for?
Zylet (loteprednol / tobramycin) is used for various eye problems, so there is no set amount of time for how long you should use this medication. I...
Can you use Zylet (loteprednol / tobramycin) for pink eye?
Zylet (loteprednol / tobramycin) can be used to treat pink eye (also known as conjunctivitis) if it's due to a bacterial infection. Keep in mind th...
Is Zylet (loteprednol / tobramycin) the same as Tobradex?
Zylet (loteprednol / tobramycin) is not the same thing as Tobradex (tobramycin / dexamethasone), but they are very similar. Both are eye medication...
Is Zylet (loteprednol / tobramycin) good for dry eyes?
There are numerous different causes of dry eyes. Zylet (loteprednol / tobramycin) may help in some situations, like if you have problems with the o...
What happens if you finish Zylet?
If you finish your prescription of Zylet (loteprednol / tobramycin) and feel like you need a refill, you will need follow-up eye exams with your provider to make sure the medication is working and not causing side effects.
What is the difference between Zylet and Tobramycin?
Zylet (loteprednol / tobramycin) contains two ingredients that work together to treat or prevent inflammation and bacterial infections of the eye. Loteprednol, a corticosteroid, lessens eye inflammation and relieves eye pain. Tobramycin, an antibiotic, prevents bacteria from making the nutrients they need to survive.
What are the side effects of Zylet (loteprednol / tobramycin)?
With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.
How much does Zylet (loteprednol / tobramycin) cost?
There is currently no generic for Zylet (loteprednol / tobramycin), so it can be expensive, even with insurance. GoodRx coupons, copay cards and patient assistance programs may help lower the cost.
Is Zylet the same as Tobradex?
Zylet (loteprednol / tobramycin) is not the same thing as Tobradex (tobramycin / dexamethasone), but they are very similar. Both are eye medications that contain tobramycin (an antibiotic) to treat or prevent bacterial infections, as well as a steroid to help with symptoms of inflammation such as swelling, itching, and pain. Zylet (loteprednol / tobramycin) is only available as a suspension (liquid) eye drop, while Tobradex (tobramycin / dexamethasone) also comes as an eye ointment.
Is Zylet a generic?
Currently, there is no generic form of Zylet ( loteprednol / to bramycin). If you're having trouble paying for it, talk to your provider to see if you can take something else for your condition. There are some other antibiotic-steroid eye medications, like Maxitrol (neomycin / polymyxin B / dexamethasone) or Tobradex (tobramycin / dexamethasone), that are available as lower-cost generic medications.
Can you stop taking zylet?
Stopping Zylet (loteprednol / tobramycin) too soon can cause your infection to come back and be harder to treat.
What is zylet used for?
Zylet is a prescription medicine used to treat the symptoms of Ocular Inflammation. Zylet may be used alone or with other medications.
What is zylet suspension?
Zylet (loteprednol etabonate and tobramycin) Ophthalmic Suspension is a sterile, multiple dose topical anti-inflammatory corticosteroid and anti-infective combination for ophthalmic use. Both loteprednol etabonate and tobramycin are white to off-white powders. The chemical structures of loteprednol etabonate and tobramycin are shown below.
What is the use of a combination drug with an anti-infective component?
The use of a combination drug with an anti-infective component is indicated where the risk of superficial ocular infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye.
Is Zylet a corticosteroid?
Zylet® is a topical anti-infective and corticosteroid combination for steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists. Ocular steroids are indicated in inflammatory conditions of the palpebral ...
Is Loteprednol etabonate teratogenic?
Pregnancy Category C. Loteprednol etabonate has been shown to be embryotoxic (delayed ossification) and teratogenic (increased incidence of meningocele, abnormal left common carotid artery, and limb fixtures) when administered orally to rabbits during organogenesis at a dose of 3 mg/kg/day (35 times the maximum daily clinical dose), a dose which caused no maternal toxicity. The no-observed-effect-level (NOEL) for these effects was 0.5 mg/kg/day (6 times the maximum daily clinical dose). Oral treatment of rats during organogenesis resulted in teratogenicity (absent innominate artery at ≥ 5 mg/kg/day doses, and cleft palate and umbilical hernia at ≥ 50 mg/kg/day) and embryotoxicity (increased post- implantation losses at 100 mg/kg/day and decreased fetal body weight and skeletal ossification with ≥ 50 mg/kg/day). Treatment of rats at 0.5 mg/kg/day (6 times the maximum daily clinical dose) during organogenesis did not result in any reproductive toxicity. Loteprednol etabonate was maternally toxic (significantly reduced body weight gain during treatment) when administered to pregnant rats during organogenesis at doses of ≥ 5 mg/kg/day. Oral exposure of female rats to 50 mg/kg/day of loteprednol etabonate from the start of the fetal period through the end of lactation, a maternally toxic treatment regimen (significantly decreased body weight gain), gave rise to decreased growth and survival and retarded development in the offspring during lactation; the NOEL for these effects was 5 mg/kg/day. Loteprednol etabonate had no effect on the duration of gestation or parturition when administered orally to pregnant rats at doses up to 50 mg/kg/day during the fetal period.
What is zylet used for?
Zylet is used to treat or prevent eye infections.
How is Zylet best taken?
Use Zylet as ordered by your doctor. Read all information given to you. Follow all instructions closely.
What are some things I need to know or do while I take Zylet?
Tell all of your health care providers that you take Zylet. This includes your doctors, nurses, pharmacists, and dentists.
What are some other side effects of Zylet?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
Who to talk to about Zylet?
Check with your pharmacist. If you have any questions about Zylet, please talk with your doctor, nurse, pharmacist, or other health care provider.
Can you take Zylet with all your medications?
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Zylet with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
How to sterilize contact lenses?
Sterilize contact lenses according to manufacturer's directions, and check with your doctor before you begin using them again. Tilt your head back, look upward, and pull down the lower eyelid to make a pouch. Hold the dropper directly over your eye and place one drop into the pouch.
Does loteprednol help with eye infections?
It also contains loteprednol, an anti-inflammatory corticosteroid that works by reducing swelling, redness, and itching .This medication treats/prevents only bacterial eye infections. It will not work for other types of eye infections and may worsen them (e.g., infections caused by viruses, fungi, mycobacteria).
Are you currently using Zylet Suspension, Drops (Final Dose Form)?
This survey is being conducted by the WebMD marketing sciences department.
What is loteprednol and tobramycin ophthalmic?
Loteprednol and tobramycin ophthalmic (for the eyes) is a combination antibiotic and steroid medicine that is used to treat eye inflammation caused by allergies, shingles ( herpes zoster ), severe acne, iritis, uveitis, eye injury, radiation, chemical burns, or certain other conditions.
Can you take loteprednol if you have herpes simplex?
You should not use this medicine if you are allergic to loteprednol or tobramycin, or if you have a fungal or viral infection in your eyes (including herpes simplex).
What is zylet used for?
Zylet (loteprednol etabonate and tobramycin) is a combination of a corticosteroid and an antibiotic used to treat eye inflammation caused by surgery, infection, allergies, and other conditions. Common side effects of Zylet include stinging, burning, irritation, itching, discomfort, ...
How long does it take for zylet to cause redness?
Common side effects of Zylet include stinging, burning, irritation, itching, discomfort, or redness of the eyes for 1 to 2 minutes when this medication is applied. Other side effects of Zylet include headache, sensitivity of the eyes to light, or blurred vision. The recommended dose of Zylet is one or two drops applied into the conjunctival sac ...
Can you take zylet while pregnant?
During pregnancy, Zylet should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding. Our Zylet (loteprednol etabonate and tobramycin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
