what medications interact with beta blockers

Full Answer

What are the side effects of beta blockers?

Side effects commonly reported by people taking beta blockers include:

• feeling tired, dizzy or lightheaded (these can be signs of a slow heart rate)
• cold fingers or toes (beta blockers may affect the blood supply to your hands and feet)
• difficulties sleeping or nightmares
• feeling sick

Which medications are beta blockers?

Drug Names. Beta-blockers include: Acebutolol ; Atenolol ; Betaxolol ; Bisoprolol (Zebeta, Ziac) Carteolol ; Carvedilol ; Labetalol (Normodyne, Trandate)

Is it safe to take Benadryl while on beta blockers?

There are no know reasons why you can't take Benadryl while on Beta blockers. I was also on a beta blocker and took benadryl. They do not interfer with each other. Beta blockers do something to slow your heart rate to lower your blood pressure. As always do not overdose on the benadryl and talk to your doctor. +1 vote! Please wait...

Can you take ibuprofen while on beta blockers?

beta-blockers such as atenolol. Taking ibuprofen with quinolone antibiotics, such as ciprofloxacin or norfloxacin, may carry an increased risk of seizures (fits), particularly in people with...

What do beta-blockers interfere with?

Beta blockers, also known as beta-adrenergic blocking agents, are medications that reduce blood pressure. Beta blockers work by blocking the effects of the hormone epinephrine, also known as adrenaline.

What reacts with beta-blockers?

beta-Blockers may interact with a large number of commonly prescribed drugs, including antihypertensive and antianginal drugs, inotropic agents, anti-arrhythmics, NSAIDs, psychotropic drugs, anti-ulcer medications, anaesthetics, HMG-CoA reductase inhibitors, warfarin, oral hypoglycaemics and rifampicin (rifampin).

What medications should not be taken with metoprolol?

Conclusion: Metoprolol should not be used concomitantly with paroxetine, fluoxetine or bupropion due to extensive interactions and the risk of serious adverse effects.

What are the two major contraindications of beta-blockers?

Contraindications and side effects High-degree AV block is an absolute contraindication (if no pacemaker) [1]. Use cardioselective beta-blockers in case of chronic obstructive pulmonary disease (COPD); start low and go slow [1]. Asthma is a relative contraindication for the use of beta-blockers [4].

What patients should avoid beta-blockers?

Beta-blockers should not be used to treat hypertension in patients older than age 60 unless they have another compelling indication to use these agents, such as heart failure or ischemic heart disease.

What is a dangerously low heart rate on beta-blockers?

Beta-blockers are contraindicated in a variety of conditions, including severe asthma as their action disrupts natural bronchodilation7. In adults, bradycardia is arbitrarily said to be any heart rate below 60 beats per minute8 and may be associated with other arrhythmia such as compensatory ventricular escape beats9.

What are the dangers of taking metoprolol?

Metoprolol may worsen the symptoms of heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort, dilated neck veins, extreme fatigue, irregular breathing or heartbeat, swelling of the face, fingers, feet, or lower legs, trouble breathing, or weight gain.

Is it better to take metoprolol at night or morning?

Your doctor may advise you to take your first dose before bedtime because it could make you feel dizzy. If you do not feel dizzy after the first dose, take metoprolol in the morning. If you have metoprolol more than once a day, try to space the doses evenly throughout the day.

What should your heart rate be on metoprolol?

They also may act to reduce rhythm disturbances by counteracting adrenaline in the blood. A heart rate of 55-60 is not unusual in people taking metoprolol.

What is the most toxic beta blocker?

Propranolol is the most toxic beta-blocker and the most frequently used in suicide attempts worldwide.

Which one is a serious complication of beta-blockers?

High blood sugar (hyperglycemia). Beta-blockers can trigger high blood sugar in people with diabetes. Depression, insomnia, and nightmares. These side effects are more common with older, nonselective beta-blockers.

What are the long term side effects of beta-blockers?

Long-term side effects of beta-blockers may include disorientation, short-term memory loss, emotional lability (rapid, extreme changes in mood), inability to concentrate or think clearly, and decreased performance on neuropsychological tests used to measure a psychological function.

What happens if you take beta-blockers with caffeine?

Coffee increases the rate at which beta-blockers are metabolized in the body. This may cause the medication to remain active in the body for a shorter period.

Why should you avoid caffeine with beta-blockers?

Beta blockers are contraindicated because they allow caffeine's (like cocaine's) unopposed alpha effects and risk of severe hypertension. In summary, caffeine ingestion is usually benign, but it may have neurologic, cardiac and gastrointestinal side effects.

Does caffeine interfere with beta-blockers?

Caffeine may reduce the effectiveness of some antihypertensive agents, particularly that of β blockers, 93 although it may not affect the response to calcium channel blockers.

What happens when you mix beta-blockers and alcohol?

Drinking alcohol while you're taking a beta-blocker can cause your blood pressure to fall. A significant drop can cause you to faint and possibly injure yourself. In addition, alcohol alone can have negative effects on the condition you're taking a beta-blocker for.

What is the clinical significance of beta blockers?

beta-blockers. Drug interactions of clinical significance. The clinician prescribing beta-blockers for his or her patients is faced with an often difficult situation. There are many beta-blockers, each with its own pharmacological profile. Patients are often taking multiple medications, thus increasing the risk of both anticipated ...

Can a prescriber be aware of a patient's other medications?

The prescriber may not be aware of the patient's other medications or lifestyle habits. Pharmacokinetic and pharmacodynamic drug interactions involving beta-blockers are documented in the literature, but these studies often examine small numbers of patients.

Can beta blockers be used with other medications?

For these reasons, it is difficult for the prac titioner to distill guidelines for the administration of beta-blockers in conjunction with other medication. In general, beta-blockers are well tolerated, and symptomatic drug interactions are relatively infrequent.

Do beta blockers have a pharmacological profile?

There are many beta-blockers, each with its own pharmacological profile. Patients are often taking multiple medications, thus increasing the risk of both anticipated and unexpected drug interactions. Reports of drug interactions are frequently anecdotal. The prescriber may not be aware of the patient's other medications or lifestyle habits.

Can a clinician prescribe beta blockers?

The clinician prescribing beta-blockers for his or her patients is faced with an often difficult situation. There are many beta-blockers, each with its own pharmacological profile. Patients are often taking multiple medications, thus increasing the risk of both anticipated and unexpected drug intera ….

What is a beta blocker used for?

Beta-blockersmay be used to treat: angina chest pain caused by narrowing of the arteries supplying the heart heart failure failure of the heart to pump enough blood around the body atrial fibri

Do beta blockers have side effects?

Most people taking beta-blockers have either no or very mild side effects that become less troublesome with time. Contact your GP ifyou're experiencing symptoms that affect your everyday life. They c

Overview

Beta-blockers are a class of medicines commonly used to treat a wide range of problems involving your heart and your circulatory system. They also are sometimes used to treat conditions related to your brain and nervous system.

Recovery and Outlook

You can use beta-blockers for extended periods. In some cases, especially for adults over 65, it’s possible to use them for years or indefinitely.

When to Call the Doctor

Your healthcare provider can advise you on when you should call or schedule an appointment related to taking beta-blockers. In general, you should call or schedule an appointment if you have a sudden change in symptoms, especially ones related to your heart and circulatory system. These include:

What hormones do beta blockers block?

Beta-blockers also obstruct the production of angiotensin II , which is a hormone that the kidneys produce. This relaxes and widens the blood vessels, easing the flow of blood through them.

How do beta blockers work?

Beta-blockers work by blocking the action of certain hormones in the nervous system, such as adrenaline. By doing this, they help prevent the activation of the “fight-or-flight” stress response. Adrenaline and noradrenaline are hormones that prepare the muscles in the body for exertion. This is a crucial part of responding to danger.

What is a beta blocker?

Beta-blockers are drugs that can lower stress on the heart and blood vessels. They can also help manage migraine, anxiety, tremor, and other conditions. Other names for beta-blockers include beta-antagonists, beta-adrenergic blocking agents, and beta-adrenergic antagonists. In this article, learn about the different types of beta-blockers, ...

Why do people use beta blockers?

The main use of beta-blockers is to manage cardiovascular symptoms.

Which type of receptors regulate cardiac activity?

There are three types. Trusted Source. of beta receptor: beta-1 (B1) receptors, which occur mainly in the heart and regulate cardiac activity. beta-2 (B2) receptors, which occur in various organs and play a role in smooth muscle relaxation and metabolic activity. beta-3 (B3) receptors, which help break down fat cells.

Is metoprolol a beta blocker?

recommended using propra nolol and metoprolol, both of which are types of beta-blocker, as a first -line therapy for preventing migraine. A 2019 review. Trusted Source. of trials from around the world concluded that propranolol was more effective than a placebo in preventing migraine and tension-type headaches.

Do beta blockers help with anxiety?

Anxiety. Beta-blockers block the effects of stress hormones. As a result, they can also reduce the physical symptoms of anxiety, such as trembling and sweating. from the Food and Drug Administration (FDA) for treating anxiety, doctors may prescribe them off-label for this purpose.

Why are beta blockers not used in asthma?

Beta blockers generally aren't used in people with asthma because of concerns that the medication may trigger severe asthma attacks. In people who have diabetes, beta blockers may block signs of low blood sugar, such as rapid heartbeat.

How does a beta blocker work?

Beta blockers work by blocking the effects of the hormone epinephrine , also known as adrenaline. Beta blockers cause your heart to beat more slowly and with less force, which lowers blood pressure. Beta blockers also help open up your veins and arteries to improve blood flow.

What is the best medicine for high blood pressure?

Beta blockers. Beta blockers treat high blood pressure and other conditions, such as heart problems. Learn why you might need them and their possible side effects. Beta blockers, also known as beta-adrenergic blocking agents, are medications that reduce your blood pressure.

Can you take beta blockers with high blood pressure?

Beta blockers aren 't recommended as a first treatment if you have only high blood pressure. Beta blockers aren't usually prescribed for high blood pressure unless other medications, such as diuretics, haven't worked effectively. Also, your doctor may prescribe a beta blocker as one of several medications to lower your blood pressure.

Do beta blockers affect the heart?

Some beta blockers mainly affect the heart, while others affect both the heart and blood vessels. Your doctor will choose which beta blocker is best for you based on your health conditions.

Can beta blockers be used for older people?

Beta blockers may not work as effectively for black people and older people, especially when taken without other blood pressure medications.

Can beta blockers cause high cholesterol?

Beta blockers can also affect your cholesterol and triglyceride levels. They can cause a slight rise in triglycerides, a type of fat in your blood, and a modest decrease in "good" cholesterol, or high-density lipoprotein (HDL) cholesterol. These changes often are temporary.

Why are beta blockers not used in asthma?

Beta blockers generally aren't used in people with asthma because of concerns that the medication may trigger severe asthma attacks.

What is a beta blocker?

Beta blockers, also known as beta-adrenergic blocking agents, are medications that reduce blood pressure. Beta blockers work by blocking the effects of the hormone epinephrine, also known as adrenaline.

Can you take beta blockers for high blood pressure?

Beta blockers aren't recommended as a first treatment in people who have only high blood pressure. Beta blockers aren't usually prescribed for high blood pressure unless other medications, such as diuretics, haven't worked well. Also, a doctor may prescribe a beta blocker as one of several medications to lower blood pressure.

Do beta blockers affect the heart?

Some beta blockers mainly affect the heart, while others affect both the heart and blood vessels. Your doctor will choose which beta blocker is best for you based on your health conditions.

Can beta blockers be used for older people?

Beta blockers may not work as effectively for black people and older people, especially when taken without other blood pressure medications.

Can beta blockers cause high cholesterol?

Beta blockers can also affect cholesterol and triglyceride levels. They can cause a slight rise in triglycerides, a type of fat in the blood, and a modest decrease in good cholesterol, or high-density lipoprotein (HDL) cholesterol. These changes often are temporary.

What are the drugs that interact with bupropion?

Drug-Drug Interactions: Antidepressants and Beta Blockers. Background: Beta blockers such as metoprolol, and antidepressants such as fluoxetine, paroxetine, duloxetine and bupropion are commonly prescribed together for the management of cardiovascular disease and depression respectively.

What is the purpose of the study on beta blockers?

Objective: The objective of the study was to investigate whether the interaction between beta blockers and antidepressants with moderate to strong CYP2D6 inhibition resulted in increased morbidity, evidenced by hospitalization or emergency department visits for hemodynamic events.

Can beta blockers cause hemodynamic events?

Conclusion: The study suggested that concurrent administration of beta blockers and antidepressants with moderate to strong CYP2D6 interaction can lead to serious hemodynamic events requiring hospitalization or an emergency department visit.

Can beta blockers cause heart rate to drop?

Concurrent administration of antidepressants and beta blockers can result in increased beta blocker exposure, which can lead to drug toxicity and events such as decreased heart rate, hypotension and falls.

Can beta blockers and antidepressants be prescribed together?

Key Point: Beta blockers and antidepressants are commonly prescribed together, and it is important that pharmacists perform a prospective drug use review to decrease adverse events from using these medications together.

What are beta blockers and how do they work?

Beta blockers, also known as beta-adrenergic blocking agents, are a class of drugs that works by blocking the neurotransmitters norepinephrine and epinephrine from binding to receptors. There are three known types of beta receptors, known as beta 1 (β 1 ), beta 2 (β 2) and beta 3 (β 3 ).

What is the second generation beta blocker?

Second generation beta blockers such as metoprolol ( Lopressor, Toprol XL ), acebutolol hydrochloride ( Sectral ), bisoprolol fumarate ( Zebeta ), esmolol hydrochloride ( Brevibloc ), betaxolol hydrochloride ( Kerlone ), and acebutolol hydrochloride (Sectral) are selective, as they block only β 1 receptors and as such will affect mostly the heart and cause reduced cardiac output.

What are the drug interactions?

Beta blockers [pindolol (Visken) and propranolol (Inderal, InnoPran)] should not be taken with phenothiazines [ thioridazine and chlorpromazine ( Thorazine )] as this will cause an increase in blood plasma levels of either or both classes of drugs. Due to the fact that increased levels of thioridazine could increase the risk of life-threatening cardiac arrhythmias, thioridazine is contraindicated in patients receiving pindolol and propranolol.

Which beta blocker has quinidine?

Beta blocker such as propranolol (Inderal, InnoPran), acebutolol hydrochloride (Sectral), and betaxolol hydrochloride (Kerlone) possess a quinidine-like or anesthetic -like membrane action, which affects cardiac action potential (electrical impulses within the heart that cause contractions).

What happens when neurotransmitters are blocked?

When the neurotransmitters are prevented from binding to the receptors, it in turn causes the effects of adrenaline (epinephrine) to be blocked . This action allows the heart to relax and beat more slowly thereby reducing the amount of blood that the heart must pump.

Which beta blocker lowers blood pressure?

Beta blockers such as labetalol hydrochloride ( Trandate, Normodyne) and carvedilol ( Coreg) have both β- and α 1 -adrenergic receptors. Blocking the α 1 -adrenergic receptors in addition to the β blocker lowers blood pressure which provides additional vasodilatory action of the arteries.

Does beta blocker cause heart failure?

Effects on the heart and circulatory system include bradycardia (slow heart rate), hypotension (low blood pressure), heart failure or heart block in patients with heart problems, cold extremities due to reduced circulation. Abrupt withdrawal of beta blockers may worsen angina ( chest pain) and cause heart attacks or sudden death.