
Drugs Derived from Plants
Drug/Chemical | Action | Plant Source |
Acetyldigoxin | Cardiotonic | Digitalis lanata (Grecian foxglove, wool ... |
Adoniside | Cardiotonic | Adonis vernalis (pheasant's eye, red cha ... |
Aescin | Antiinflammatory | Aesculus hippocastanum (horse chestnut) |
Aesculetin | Antidysentery | Frazinus rhychophylla |
What prescription drugs are derived from plants?
According to the Memorial Sloan-Kettering Cancer Center:
- A few clinical trials show that when combined with chemotherapy lentinan increases the survival time of people with certain types of cancer.
- Lab studies and a few human studies show that lentinan boosts the activity of specific cells within the immune system.
- In the lab, lentinan has destroyed viruses and bacteria. ...
What products are derived from plants?
positive influence of social media and increasing health-conscious consumers around the world who prefer products with less calories create new opportunities for the global Plant Derived Sugar and Synthetic Sugar industry. However, high prices of these ...
What are drugs made from plants?
- Acetyldigoxin for Cardiotonic from Digitalis lanata
- Adoniside for Cardiotonic from Adonis vernalis
- Aescin for Antifrominflammatory from Aesculus hippocastanum
- Aesculetin for Antifromdysentery from Frazinus rhychophylla
- Agrimophol for Anthelmintic from Agrimonia supatoria
- Benzyl benzoate for Scabicide from Several plants
What are medicines made from plants?
Nature’s 9 Most Powerful Medicinal Plants and the Science Behind Them
- We scoured through histories of herbal studies for you. Today, we live in a time when manufactured medicines and prescriptions prevail, but do they have to be the only approach ...
- Gingko. ...
- Turmeric. ...
- Evening primrose oil. ...
- Flax seed. ...
- Tea tree oil. ...
- Echinacea. ...
- Grapeseed extract. ...
- Lavender. ...
- Chamomile. ...

What are some plants that are used for medicine?
People have used plants to make medicines since prehistoric times. Early plants used for medicines include herbs and spices, which were used to reduce food spoilage and parasites, not just as flavoring. The 60,000-year-old Neaderthal burial “Shanidar IV” included pollen from plant species that are used as herbal remedies. Ötzi the Iceman had a mushroom, likely used as a whipworm remedy, that was counted among his personal effects when his body was recovered after 5,000 years frozen in the ice. The ancient Sumerians lists myrrh, opium, and hundreds of other plants on clay tablets. The Egyptian Ebers Papyrus, dated to around 1550 BC, listed over 850 medicinal plants, including juniper, aloe, and cannabis.
What are medicines made of?
Medicines Made From Plants . This entry was posted on May 21, 2020 by Anne Helmenstine (updated on May 6, 2021) Many drugs and medicines are derived from plants. Medicines made from plants have been used throughout human history. Today, over 100 drugs and medicines trace their “roots” to chemical compounds found in plants.
How many drugs are traced to plants?
Today, over 100 drugs and medicines trace their “roots” to chemical compounds found in plants. Here is a table of plants, the compound used as a drug, and the medical use of the drug. While it is not a comprehensive list of all of the plants, names of chemicals, or uses for those chemicals, it’s a helpful starting point for further research.
What are polyphenols?
Polyphenols occur in many dietary supplements. Terpenes – Terpenes and turpenoids are chemically related to the hydrocarbon isoprene. These volatile organic compounds are the source of a plant’s fragrance and essential oils. Plants use them to attract pollinators and repel herbivores.
Why do plants use phytochemicals?
The plant uses these pharmacological phytochemicals mainly to deter herbivores, parasites, and insect pests and to keep other plants from getting too close. Basically, these compounds tend to be natural herbicides, pesticides, and insecticides, so they are usually toxic to humans at high levels.
What are glycosides used for?
They are used medically as laxatives, diuretics, and heart tonics.
Plant compounds
Plant polysaccharides have immunomodulatory or immunostimulatory effects, such as Ganoderma lucidum, Cordyceps sinensis and Açaí fruit.
Traditional herbal medicine
Overall, half the drugs in use today in any category come from over 35,000 plants. India and China meet half their demand for primary healthcare in the form of THM, catering to about four million people in all.
Examples of modern drug discovery from plants
An outstanding example of such a drug discovery process is artemisinin derivatives from Artemisia annua. Also known as Qing-hao in Chinese, this plant yields a highly oxygenated sesquiterpene called Qinghaosu, or artemisinin. This is poorly bioavailable on oral administration despite its potent antimalarial activity.
Current issues
The target molecules associated with drug use or diseases do not reflect in current therapies. Secondly, single-target approaches fail to encompass the complexity of the human organism, with multiple contributing factors for every disease condition, including genetic and environmental.
Future directions
As stated above, herbal medicine is a huge go-to for primary health care. This could change if these herbs are over-exploited by Big Pharma, making them rare or endangered, while pushing up the price beyond the limit of affordability. One possible answer to this problem is herb farming and agrotechnology.
What is the main ingredient in aspirin?
The main ingredient in Aspirin is salix , also known as salicylic acid. Salix is a powdery white substance that is found in the bark of the willow tree. Hippocrates, who was known as the father of modern medicine, discovered its medicinal benefits.
What is codeine made of?
Codeine is one of the most commonly prescribed medicines made from plants. Derived from a chemical that is extracted from the poppy plant, codeine belongs to the group of medicines that are known as opioids. It is used to treat various different ailments.
Where does camphor come from?
Camphor is made from the cinnamomum camphora plant, which is also known as the camphor tree. This tree is native to certain parts of Asia. It is used in creams and lotions that are designed for topical application, to treat numerous troubling skin conditions.
Which compound can be produced synthetically?
A compound that can be produced synthetically, is less bitter and has less stomach irritation. #1: Metformin. And finally we have the French Iliac, also known as Galega Officinalis. It contains a substance called Guanidine, which was found in 1918 to have blood sugar lowering effects.
What is the plant that is used to make opium?
Next up is the poppy of the plant Papaver Somniferum. In the early 1800s, a German pharmacist called Friedrich Sertürner was so curious about the effects of the opium poppy, that he started experimenting on stray dogs and then on himself.
What is the best treatment for chloroquine?
Today, Artemisinin based therapies are used as first line treatment where Chloroquine is no longer effective. #2: Aspirin. Modern day Aspirin has its roots in ancient medicines derived from the Willow tree. The ancient Egyptians mentioned using willow and myrtle to treat pain and fever.
What is the enzyme that makes gene editing?
Researchers looked at the immune system of bacteria and found an enzyme called Cas9 which can make specific gene edits. If you’d like to learn more about where CRISPR technology may take us in the future, click on the video on your right. Thanks for watching and I’ll see you in the next one.
Who invented the compound aspirin?
In 1828, the German chemist Johann Buchner called this compound Salicin. But extraction from the willow bark was difficult and wasteful. Eventually the combined work of multiple chemists led to the formulation of modern day Aspirin – acetylsalicylic acid.
Is being a plant hard?
This may surprise you, but being a plant is hard work. It’s not all about sunbaking and soaking up the rain. Plants are constantly fighting off pests, defending themselves from fungi and protecting their themselves from pesky plant eating animals.
What are some examples of drugs that are derived from plants?
Some examples include: Antibiotics. Chemotherapy. Pain management. Hallucinogenics. Here are some of the most common drugs that were derived from, or inspired by compounds found in plants. 1. Aspirin (Salicylic Acid) Aspirin is a popular treatment for pain, inflammation, and fever.
How is yew medicine made?
The drug is now made using semisynthetic methods obtained from liquid plant cultures. Although the plant tissue is still needed to make the medicine, it poses no threat to wild yew populations because manufactures now rely on sterile lab-grown cultures of the plant.
What is the antibiotic derived from the sterile fungus Mycelia sterilia?
4. Myriocin. Myriocin (aka ISP-1 or thermozymocidin), is an antibiotic and immunosuppressant derived from the sterile (non-spore-producing) fungus Mycelia sterilia and entomopathogenic (bug-eating) fungus Isaria sinclairii.
What is the difference between aspirin and acetyl?
All of these plants were traditionally used for conditions involving injury, pain, and inflammation. The difference Aspirin has to its naturally occurring counterpart is the addition of an acetyl chemical group, which gives Aspirin its antifibrinolytic effects and improved bioavailability. 2.
How does aspirin work?
It works by inhibiting an enzyme known as cyclooxygenase (COX). The COX-1 enzyme converts arachidonic acid to thromboxanes and prostaglandins which are responsible for sustaining inflammation and blood clotting. The compound was first synthesized in 1890 by a man named Felix Hoffmann. Aspirin is modelled after the naturally occurring polyphenol ...
What is the compound used to treat multiple sclerosis?
Scientists modified myriocin to produce a compound known as fingolimod (compound FTY720), which is used to treat autoimmune conditions like multiple sclerosis. 5. Penicillin. Penicillin was the very first class of antibiotics ever discovered. It’s made from a mould known as Penicillium chrysogenum.
How does penicillin work?
They work by blocking a key process during cell division (peptidoglycan cross-link formation), causing the cell to eject its insides, effectively killing the bacteria. This is most effective in gram-positive bacteria.
How long have plants been used in medicine?
Before modern medicine and the manufacture of synthetic drugs, plants had been in use as medication probably as long as humans have existed. There are even reports of chimpanzees using leaves to self-medicate.
Why are there more medicines in the rainforest?
Scientist know that many rainforest plants are rich in alkaloids which protect them from disease and insect attacks so there are certain to be more medical drugs derived from them in the future.
What is the name of the plant that is used for breast cancer?
Gabrielle Hatfield ( New Scientist 14th Oct 1995) found early 18th-century records of a treatment for breast cancer being a poultice of periwinkle plants (species of Vinca).
What is the best plant for worms?
Lesser Celendine (Ranunculus ficaria) – used for digestive system disorders and piles. Compass plant (Silphium laciniatum) – used to induce vomiting (an emetic) and for digestive system disorders. Wormwood (Artemisia brevifolia) – used as an anthelmintic to treat intestinal worms.
Why is opium used in fens?
Opium or laudanum from opium poppies (Papaver somniferus) has been used for hundreds of years to sooth pain. It was even given to Victorian babies who kept their mother’s awake with teething pain and a lot of it was consumed in fens of East Anglia to give pain relief to malaria victims (New Scientist. Fred Pearce. December 2001). Malaria was still common in the fens at that time because the malaria mosquito thrived in the marshland.
Which species of Cinchona produces the most quinine?
One species which proved to be quinine rich was Cinchona. ledgeriana.
What is a compass plant?
Compass plant (Silphium laciniatum) – used to induce vomiting (an emetic) and for digestive system disorders.
What are some plants that are used as medicine?
Plants and plant extracts have been used as medicines for thousands of years. Indeed, the first Botanic Garden here in Cambridge was set up in 1762 as a ‘Physic Garden’, with plants arranged according to which area of the body they would treat. Some traditional remedies such as Willow and Foxglove have subsequently been shown to have a scientific basis to their use as treatments. However, many others were ineffective, particularly those identified using the theory of the ‘Doctrine of Signatures’, which ascribed therapeutic properties to plants based on their resemblance to body parts. Walnut kernels, for example, resemble brains, so walnuts were used to treat headaches and mental illness.
How many terpenoids are there in plants?
Over 20,000 terpenoids have been described. They include steroids, resins, latexes and essential oils (which derive their name from the fact that they have an aroma characteristic of the ‘essence’ of the plant, rather than because they are essential for the plants’ survival). Some essential oils attract pollinators, while others prevent herbivory.
What are secondary metabolites?
Secondary metabolites generally fall into one of three categories: terpenoids, alkaloids and phenols.
Can plants get up and run away?
(This is the online version of the paper booklet available at ticket offices in the Garden.) When faced with a predator, plants cannot get up and run away, so must protect themselves with an arsenal of chemicals. Because these chemicals tend to work by interfering ...
Do alkaloids kill herbivores?
Alkaloids are often extremely poisonous to humans and other animals. Again, they deter herbivory – in the most extreme cases by killing the herbivore. They can also help plants dominate their patch of land – for example, Coffee ( Coffea arabica) leaves contain caffeine, which they release into the soil when they fall and decay, and which inhibits the germination of other seedlings.
What are the most common drugs that are derived from plants?
In fact, at the beginning of the 21st century, 11 percent of the 252 drugs considered “basic and essential” by the World Health Organization were “exclusively of flowering plant origin.” Drugs like codeine, quinine, and morphine all contain plant-derived ingredients.
Where does tea tree oil come from?
Tea tree oil is derived from the leaves of a tree that’s native to Queensland and New South Wales, Australia.
How long has turmeric been used?
Turmeric has been used as a medicinal herb for 4,000 years. It’s a tentpole of an Indian alternative medicine practice called Ayurveda.
Is evening primrose oil a medicine?
According to these studies, evening primrose oil might just be the Swiss Army knife of the medicinal plant world. The caveat is that it can interact with several medications. More research is coming, and the applications are promising.
Can you use herbs on babies?
Pay attention to what the evidence says about each herb’s effectiveness as well as potential interactions or safety issues. Avoid using herbs for infants and children and for those who are pregnant and breastfeeding.
Is it safe to take herbs without medication?
Most herbs haven’t been tested for safety for those who are vulnerable, and trying herbs isn’t worth the risk. With this cautionary tale in mind, choosing the right plant can seem difficult to someone who simply wants to feel better without taking medication.
Is codeine a plant derived drug?
Drugs like codeine, quinine, and morphine all contain plant-derived ingredients. While these manufactured drugs have certainly become paramount in our lives, it can be comforting to know that the power of nature is on our side, and these herbal choices are available to complement our health practices.

Plant Compounds
- Plant polysaccharides have immunomodulatory or immunostimulatory effects, such as Ganoderma lucidum, Cordyceps sinensisand Açaí fruit. Flavonoids, found in almost all plants, are compounds with a heterocyclic ring structure consisting of an aromatic ring and a benzopyran ring with a phenyl substituent and include flavones, isoflavone, flavonols, flavonones, and xanth…
Traditional Herbal Medicine
- Overall, half the drugs in use today in any category come from over 35,000 plants. India and China meet half their demand for primary healthcare in the form of THM, catering to about four million people in all. In China, it is estimated that 140 new drugs are being used at present, either directly extracted from plants or chemically modified. Using the wealth of experiential data from decade…
Examples of Modern Drug Discovery from Plants
- An outstanding example of such a drug discovery process is artemisinin derivatives from Artemisia annua. Also known as Qing-hao in Chinese, this plant yields a highly oxygenated sesquiterpene called Qinghaosu, or artemisinin. This is poorly bioavailable on oral administration despite its potent antimalarial activity. It was therefore reduced, yield...
Databases of Thm
- Multiple herbal medicine databases are available, including: 1. Traditional Chinese medicine information database (TCM-ID), containing more than 47,000 prescriptions for herbal formulations, over 8,000 herbs, over 25,000 compounds and the 3-D structure of thousands of them, besides diseases, drugs and related targets. This data has been used to model the therap…
Current Issues
- The target molecules associated with drug use or diseases do not reflect in current therapies. Secondly, single-target approaches fail to encompass the complexity of the human organism, with multiple contributing factors for every disease condition, including genetic and environmental. Despite the fact that systems pharmacology offers a powerful new approach for drug discovery …
Future Directions
- As stated above, herbal medicine is a huge go-to for primary health care. This could change if these herbs are over-exploited by Big Pharma, making them rare or endangered, while pushing up the price beyond the limit of affordability. One possible answer to this problem is herb farming and agrotechnology. The establishment of herb farms has become an industry in China, with go…
References
- Pan, S.-Y. et al. (2013). New Perspectives on How to Discover Drugs from Herbal Medicines: CAM's Outstanding Contribution to Modern Therapeutics. Evidence-Based Complementary and Alternative Medici...
- Veeresham, C. (2021). Natural Products Derived from Plants As A Source Of Drugs. Journal of Advanced Pharmaceutical Technology and Research. https://dx.doi.org/10.4103%2F2231-40…
- Pan, S.-Y. et al. (2013). New Perspectives on How to Discover Drugs from Herbal Medicines: CAM's Outstanding Contribution to Modern Therapeutics. Evidence-Based Complementary and Alternative Medici...
- Veeresham, C. (2021). Natural Products Derived from Plants As A Source Of Drugs. Journal of Advanced Pharmaceutical Technology and Research. https://dx.doi.org/10.4103%2F2231-4040.104709. https://w...
- Atanasov, A. G. et al. (2015). Discovery and Resupply of Pharmacologically Active Plant-Derived Natural Products: A Review. Biotechnology Advances. https://doi.org/10.1016/j.biotechadv.2015.08.001....
- Lavania, U. C. (2016). Evolving Trends In Plant-Based Drug Discovery. Published online by Ca…
Further Reading