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what type of toxin is ciguatera

by Otha Hudson Published 2 years ago Updated 2 years ago
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Ciguatera fish poisoning (or ciguatera) is an illness caused by eating fish that contain toxins produced by a marine microalgae called Gambierdiscus toxicus. People who have ciguatera may experience nausea, vomiting, and neurologic symptoms such as tingling fingers or toes.

How to avoid ciguatera poisoning?

This is not an exclusive list, but it's a guide that should keep you out of trouble:~

  • Seek out, listen and adhere to local advice.
  • Avoid eating large fish of any species that are known to host the ciguatera toxin.
  • Only eat the flesh of the fish - never its liver, gills, guts or any of its other internal organs.
  • Make sure to clean all fish thoroughly before cooking.

Which type of microbe produces toxins?

The organisms which are capable of producing toxins include bacteria, fungi, algae, and plants. Some of the major types of toxins include, but are not limited to, environmental, marine, and microbial toxins. Microbial toxins may include those produced by the microorganisms bacteria (i.e. bacterial toxins) and fungi (i.e. mycotoxins).

What are the different types of toxins?

  • Hemotoxin, causes destruction of red blood cells ( hemolysis)
  • Phototoxin, causes dangerous photosensitivity
  • Hepatotoxin s affect the liver
  • Neurotoxin s affect the nervous system

How to tell if a fish has ciguatera?

  • Gastrointestinal symptoms: Characterize the first stage of ciguatera poisoning and appear within 12 hours of consuming the contaminated fish, lasting for a couple of days.
  • Neurological symptoms: The next set of symptoms affects the neurological system. ...
  • Cardiovascular symptoms: The third set of symptoms affects the cardiovascular system.

More items...

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What type of toxin is ciguatera toxin bacterial?

Ciguatera toxicity is a food-borne illness caused by eating fish contaminated with Ciguatoxin. This toxin is a potent neurotoxin, and it is produced by Dinoflagellates, such as Gambierdiscus toxicus. They adhere to algae, coral, and seaweed, where herbivorous fish eat them.

What is ciguatera toxin commonly found in?

Ciguateria can accumulate in reef fish that eat other fish. Fish you may want to avoid include barracuda, moray eel, grouper, amberjack, sea bass, sturgeon, parrot fish, surgeonfish, and red snapper.

Is ciguatera poisoning a bacteria?

Ciguatera poisoning is a form of food poisoning. It is caused by eating warm water ocean finfish that carry ciguatera poison (a toxin). This poison is produced by a very tiny organism called a dinoflagellate, which attaches itself to algae growing in warm ocean water reef areas.

Is ciguatera a chemical?

Ciguatera is a significant food-borne disease caused by potent polyether toxins (ciguatoxins) which accumulate in the flesh of ciguateric reef fish at risk levels > 0.1 ppb for Pacific ciguatoxins.

What is ciguatera fish poisoning caused by?

About Ciguatera Ciguatera fish poisoning (or ciguatera) is an illness caused by eating fish that contain toxins produced by a marine microalgae called Gambierdiscus toxicus. People who have ciguatera may experience nausea, vomiting, and neurologic symptoms such as tingling fingers or toes.

Do all fish have ciguatera?

Any reef fish can cause ciguatera poisoning, but species such as barracuda, grouper, red snapper, moray eel, amberjack, parrotfish, hogfish, sturgeonfish, kingfish, coral trout, and sea bass are the most commonly affected. Ciguatoxins are concentrated in the fish liver, intestines, heads, and roe.

Is ciguatera a virus?

Ciguatera fish poisoning (CFP), also known simply as ciguatera, is a foodborne illness caused by eating reef fish whose flesh is contaminated with certain toxins....Ciguatera fish poisoningSpecialtyToxicologySymptomsDiarrhea, vomiting, numbness, itchiness, sensitivity to hot and cold, dizziness, weakness12 more rows

Is there a cure for ciguatera?

There is no specific cure for ciguatera fish poisoning, but symptoms can be treated until the illness resolves on its own. Most poisoning resolves in a few days or weeks, but in severe cases the neurologic symptoms may last for weeks or months.

Does tuna have ciguatera?

Sometimes fish are ciguatoxic only in certain areas and at certain times of the year. Outbreaks of ciguatera are unpredictable and may spread from one area to another. You cannot get ciguatera poisoning from open ocean fish such as tuna, mahi mahi, marlin or deepwater snapper.

What chemical toxin is from grouper fish?

The most commonly reported marine toxin disease in the world is Ciguatera, associated with consumption of contaminated reef fish such as barracuda, grouper, and snapper.

How common is ciguatera toxin?

Ciguatera fish poisoning is a rare disorder that occurs because of the ingestion of certain contaminated tropical and subtropical fish. When ingested, the toxin (ciguatoxin), which is present at high levels in these contaminated fish, may affect the digestive, muscular, and/or neurological systems.

Is ciguatera a red tide?

Human ciguatera fish poisoning in the Gulf may be underreported or not diagnosed yet. The toxin is no doubt present in the Gulf. Dinoflagellates are implicated in causing the “red tide” phenomenon in the Gulf, also known as an algal bloom. The photosynthetic pigment in the algae gives it the red coloration.

Where can ciguatoxin be found?

Ciguatoxins are toxins found in seafood that occurs from fish that consume dinoflagellates or other toxic elements and are then eaten by people.

How do I get rid of ciguatera?

There is no specific cure for ciguatera fish poisoning, but symptoms can be treated until the illness resolves on its own. Most poisoning resolves in a few days or weeks, but in severe cases the neurologic symptoms may last for weeks or months.

Is ciguatera common?

At least 50,000 people per year who live in or visit tropical and subtropical areas suffer from Ciguatera worldwide. For example, CDC and others estimate that only 2-10% of Ciguatera cases are actually reported in the United States.

How do you prevent ciguatera poisoning?

Travelers can take the following precautions to prevent ciguatera fish poisoning: Avoid or limit consumption of reef fish. Never eat high-risk fish such as barracuda or moray eel. Avoid eating the parts of the fish that concentrate ciguatera toxin: liver, intestines, roe, and head.

How long does it take for ciguatera to cause nausea?

Eating ciguatera toxin contaminated fish result in the following symptoms: Symptoms generally begin 6 to 8 hours after eating the contaminated fish but can occur as early as 2 or as late as 24 hours after ingestion. Symptoms include nausea, vomiting, diarrhea, muscle pain, numbness, tingling, abdominal pain, dizziness, and vertigo.

What is ciguatera toxin?

Ciguatera is a foodborn illness ( food poisoning) caused by eating fish that is contaminated by ciguatera toxin. Ciguatera toxin is a heat-stable lipid soluble compound, produced by dinoflagellates and concentrated in fish organs, that can cause nausea, pain, cardiac, and neurological symptoms in humans when ingested.

What to take for ciguatera rash?

Diphenhydramine (Benadryl) and hydroxyzine (Atarax, Vistaril) may help relieve itching. Avoid alcohol, fish, nuts, and nut oils after exposure to ciguatera toxin because they may trigger recurrent symptoms.

How long does it take for activated charcoal to absorb?

Activated charcoal may absorb the toxin if done 3 to 4 hours after ingestion. Maintain hydration. Intravenous fluids may be necessary for uncontrollable nausea and vomiting. No specific antidote is available. Osmotic diuretics have been used to decrease symptoms (for example, mannitol [ Osmitrol ]).

What does it mean when you feel hot and cold?

The classic finding of hot and cold sensation reversal is actually a burning sensation on contact with cold (allodynia). Teeth may feel loose and itching may be intense. Severe cases of ciguatera poisoning may result in shortness of breath, salivation, tearing, chills, rashes, itching, and paralysis. Bradycardia, coma and hypotension can occur.

What is the main way that humans are exposed to the toxin?

Eating ciguatera-contaminated tropical or subtropical fish is the main way that humans are exposed to the toxin. The toxin activates voltage-dependent sodium channels causing symptoms in human (and other mammals) gastrointestinal, cardiac, and nerve tissues.

Where do ciguatera live?

These fish live in coral reef waters and accumulate the toxin when they eat smaller reef fish which feed on the dinoflagellates. The area of concern include the Caribbean Sea, Hawaii, and coastal Central America. With fish from ciguatera endemic areas being shipped nationwide, poisonings can potentially occur in any areas in the United States.

What are the symptoms of ciguatera poisoning?

Symptoms of ciguatera poisoning generally begin six to eight hours after eating the contaminated fish.

What is antizol used for?

Antizol (fomepizole) Antizol (fomepizole) is an antidote used to treat poisoning with ethylene glycol (antifreeze) or methanol (contained in solvents, fuels, and other household or automotive chemicals). Antizol is sometimes used together with hemodialysis to rid the body of a poison.

What is the medication used for a tremor?

Atropen (atropine) is a prescription medicine used to treat the symptoms of Anesthesia Premedication, Sinus Bradycardia (ACLS), Bronchospasm, and Organophosphate or Carbamate Poisoning. Atropen may be used alone or with other medications. Serious side effects of Atropen include restlessness, tremor, fatigue, coordination difficulties, confusion, hallucinations, depression, loss of muscle control on one side, sensation loss on one side of the face, nausea, difficulty speaking, vomiting, and cardiac arrest.

What is the ciguatera?

Ciguatera is a type of food poisoning. The ciguatera toxin may be found in large reef fish, most commonly barracuda, grouper, red snapper, eel, amberjack, sea bass, and Spanish mackerel. These fish live in coral reef waters between latitudes of 35 degrees south to 35 degrees north, corresponding to the area located between the Tropic of Cancer and the Tropic of Capricorn. These geographic lines ring the earth north and south of the equator and make up the tropics. These areas include the Caribbean Sea, Hawaii, and coastal Central America.

Where is ciguatera toxin found?

These areas include the Caribbean Sea, Hawaii, and coastal Central America. Ciguatera toxin tends to accumulate in predator fish, such as the Barracuda and other carnivorous reef fish because they eat other fish that consume toxin-producing algae (dinoflagellates) that live in coral reef waters. Ciguatera toxin is harmless to fish ...

How are seizures produced?

Generalized seizures are produced by electrical impulses from throughout the brain , while partial seizures are produced by electrical impulses in a small part of the brain. Seizure symptoms include unconsciousness, convulsions, and muscle rigidity.

Why do I get vertigo?

Vertigo may be caused by a problem in the brain or spinal cord or a problem within in the inner ear. Head injuries, certain medications, and female gender are associated with a higher risk of vertigo. Medical history, a physical exam, and sometimes an MRI or CT scan are required to diagnose vertigo.

What is the number to call for ciguatera poisoning?

If you think you may have ciguatera poisoning, call the New York City Poison Control Center at 800-212-POISONS (800-222-1222) . To report a case of ciguatera fish poisoning, call 311.

Which fish has the highest ciguatoxin levels?

The bigger the fish, the more ciguatoxin it contains. The highest levels of ciguatoxin are usually found in large, predatory reef fish. This includes barracuda, grouper, amberjack, snapper and mackerel. Fish with ciguatoxins do not look, smell or taste differently from fish without ciguatoxins.

How to treat ciguatera poisoning?

There is no effective treatment or antidote for ciguatera poisoning. The mainstay of treatment is supportive care. There is some evidence that calcium channel blockers like nifedipine and verapamil are effective in treating some of the symptoms that remain after the initial sickness passes, such as poor circulation and shooting pains through the chest. These symptoms are due to vasoconstriction caused by maitotoxin. Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. Opening a sodium channel causes depolarization, which could sequentially cause paralysis, heart contraction, and changing the senses of hot and cold. Some medications such as amitriptyline may reduce some symptoms, such as fatigue and paresthesia, although benefit does not occur in every case.

How many people died from ciguatera poisoning in 2016?

During October 2016, more than 100 people suffered from ciguatera poisoning after eating fish heads supplied by an export firm in Mangalore, India.

What is a ciguatera fish?

Ciguatera fish poisoning ( CFP ), also known simply as ciguatera, is a foodborne illness caused by eating reef fish whose flesh is contaminated with certain toxins. Such individual fish are said to be ciguatoxic. Symptoms may include diarrhea, vomiting, numbness, itchiness, sensitivity to hot and cold, dizziness, and weakness.

What is the medicinal use of octopus bush?

Leaves of Heliotropium foertherianum (Boraginaceae) – also known as octopus bush – are used in many Pacific islands as a traditional medicine to treat ciguatera fish poisoning. Senescent octopus bush leaves contain rosmarinic acid and derivatives, which are known for their antiviral, antibacterial, antioxidant, and anti-inflammatory properties. Rosmarinic acid may remove the ciguatoxins from their sites of action, as well as being an anti-inflammatory.

How long does a ciguatera rash last?

The symptoms can last from weeks to years, and in extreme cases as long as 20 years, often leading to long-term disability. Most people do recover slowly over time.

Why can't you eat fish in Dominican Republic?

In Dominican Republic, another common belief is that during months whose names do not include the letter "R" (May through August), it is not recommended to eat certain kinds of fish, because they are more likely to be infected by the ciguatera toxin.

How to test for ciguatoxin in fish?

The first method is that flies are supposed not to land on contaminated fish. The second is that cats will either refuse to eat or vomit/display symptoms after eating contaminated fish. A third, less common testing method involves putting a silver coin under the scales of the suspect fish. If the coin turns black, according to the theory, it is contaminated.

What is the cause of ciguatera fish poisoning?

Ciguatera fish poisoning is caused by a toxin (ciguatoxin) found in tropical or subtropical fish during certain times of the year. The source of the toxin responsible for ciguatera fish poisoning is found in high levels in a marine organism (dinoflagellate Gamabierdiscus toxicus) that typically inhabits low-lying tropical shore areas and coral reefs. As local fish feed on this organism, toxin accumulates in their bodies and ultimately causes ciguatera fish poisoning when humans consume the fish.

What is a ciguatera fish?

Ciguatera fish poisoning is a rare disorder that occurs because of the ingestion of certain contaminated tropical and subtropical fish. When ingested, the toxin (ciguatoxin), which is present at high levels in these contaminated fish, may affect the digestive, muscular, and/or neurological systems. More than 400 different species of fish have been implicated as a cause of ciguatera fish poisoning, including many that are otherwise considered edible (i.e., sea bass, snapper, and perch). These fish typically inhabit low-lying shore areas or coral reefs in tropical or subtropical areas. In the United States, ciguatera fish poisoning has occurred more frequently in the last decade perhaps as a result of a general increase in fish consumption.

How long does it take for ciguatera to get numb?

The symptoms of acute ciguatera fish poisoning may begin as soon as 30 minutes after eating contaminated fish. The initial symptoms may include itching, tingling, and numbness of the lips, tongue, hands, and/or feet. Other symptoms during the first six to 17 hours are abdominal cramps, nausea, vomiting, diarrhea, and/or a red skin rash (pruritus). Chills, hot and cold temperature reversal, generalized weakness, restlessness, dizziness, wheezing, blurred vision, abnormal sensitivity to light (photophobia), muscle aches (myalgias), and/or joint pain (arthralgias) may also develop.

Where does ciguatera occur?

This disease occurs with the greatest frequency in tropical and subtropical countries , particularly those in the Pacific and Caribbean areas. All age groups are at risk for this disease. However, a longer duration and more severe symptoms of ciguatera fish poisoning may be associated with increasing age. Children seem to experience milder symptoms ...

How long does it take for a coma to occur?

Life-threatening complications (i.e., abnormally slow heartbeat, respiratory arrest, convulsions, or coma) may occur in these severe cases within 24 hours.

Can ciguatera fish be passed to a female?

The presence of ciguatoxin has been reported in semen from affected males which can cause the symptoms of ciguatera fish poisoning in females after sexual intercourse. Since this toxin has also been identified in breast milk, it is also possible for affected mothers to pass this disease to their nursing children.

Can cooking kill ciguatera?

As local fish feed on this organism, toxin accumulates in their bodies and ultimately causes ciguatera fish poisoning when humans consume the fish. No known method of cooking can destroy the ciguatoxin in contaminated fish. It is possible that more than one form of the toxin may be present in a fish.

How to treat ciguatera poisoning?from en.wikipedia.org

There is no effective treatment or antidote for ciguatera poisoning. The mainstay of treatment is supportive care. There is some evidence that calcium channel blockers like nifedipine and verapamil are effective in treating some of the symptoms that remain after the initial sickness passes, such as poor circulation and shooting pains through the chest. These symptoms are due to vasoconstriction caused by maitotoxin. Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. Opening a sodium channel causes depolarization, which could sequentially cause paralysis, heart contraction, and changing the senses of hot and cold. Some medications such as amitriptyline may reduce some symptoms, such as fatigue and paresthesia, although benefit does not occur in every case.

How many people died from ciguatera poisoning in 2016?from en.wikipedia.org

During October 2016, more than 100 people suffered from ciguatera poisoning after eating fish heads supplied by an export firm in Mangalore, India.

What is the cause of ciguatera fish poisoning?from rarediseases.org

Ciguatera fish poisoning is caused by a toxin (ciguatoxin) found in tropical or subtropical fish during certain times of the year. The source of the toxin responsible for ciguatera fish poisoning is found in high levels in a marine organism (dinoflagellate Gamabierdiscus toxicus) that typically inhabits low-lying tropical shore areas and coral reefs. As local fish feed on this organism, toxin accumulates in their bodies and ultimately causes ciguatera fish poisoning when humans consume the fish.

What is a ciguatera fish?from en.wikipedia.org

Ciguatera fish poisoning is a rare disorder that occurs because of the ingestion of certain contaminated tropical and subtropical fish. When ingested, the toxin (ciguatoxin), which is present at high levels in these contaminated fish, may affect the digestive, muscular, and/or neurological systems. More than 400 different species of fish have been implicated as a cause of ciguatera fish poisoning, including many that are otherwise considered edible (i.e., sea bass, snapper, and perch). These fish typically inhabit low-lying shore areas or coral reefs in tropical or subtropical areas. In the United States, ciguatera fish poisoning has occurred more frequently in the last decade perhaps as a result of a general increase in fish consumption.

What is the medicinal use of octopus bush?from en.wikipedia.org

Leaves of Heliotropium foertherianum (Boraginaceae) – also known as octopus bush – are used in many Pacific islands as a traditional medicine to treat ciguatera fish poisoning. Senescent octopus bush leaves contain rosmarinic acid and derivatives, which are known for their antiviral, antibacterial, antioxidant, and anti-inflammatory properties. Rosmarinic acid may remove the ciguatoxins from their sites of action, as well as being an anti-inflammatory.

How long does it take for ciguatera to get numb?from rarediseases.org

The symptoms of acute ciguatera fish poisoning may begin as soon as 30 minutes after eating contaminated fish. The initial symptoms may include itching, tingling, and numbness of the lips, tongue, hands, and/or feet. Other symptoms during the first six to 17 hours are abdominal cramps, nausea, vomiting, diarrhea, and/or a red skin rash (pruritus). Chills, hot and cold temperature reversal, generalized weakness, restlessness, dizziness, wheezing, blurred vision, abnormal sensitivity to light (photophobia), muscle aches (myalgias), and/or joint pain (arthralgias) may also develop.

How long does a ciguatera rash last?from en.wikipedia.org

The symptoms can last from weeks to years, and in extreme cases as long as 20 years, often leading to long-term disability. Most people do recover slowly over time.

How to reduce the risk of ciguatera poisoning?

Since it is very difficult to immediately detect a fish with ciguatera, the most appropriate way to reduce the risk of consuming the fish is to recognize which fish are most susceptible to ciguatera toxin.

Can ciguatera be cooked out?

Fish with ciguatoxin can not be detected by appearance, taste, or odor, and the toxin is not removed by freezing, filleting, or cooking the fish. There is currently no FDA-approved test for ciguatoxin.

Can you get ciguatera from eating salmon?

Salmon is a sea fish and also a freshwater fish regularly found in the oceans, this type of fish is not exposed to ciguatoxin.

What is the most common fish poisoning?

Ciguatera is one of the most common fish poisonings worldwide, caused by ciguatoxins present in edible fish.

Where does ciguatera come from?

As well as in which parts of the body ciguatoxin accumulates in a fish, ciguatera is a toxin obtained from small reef-feeding fish in the Pacific and the Caribbean Sea.

What is the term for an abnormal sensation of tissues, cold and/heat, tingling, and sensitivity?

An abnormal sensation of tissues, cold and/heat, tingling (paresthesia) and sensitivity disorder (dysesthesia).

Can you detect ciguatera fish with the naked eye?

The problem is that a ciguatera fish is impossible to detect with the naked eye or human senses, because ciguatoxin is odorless, colorless, does not alter the taste of the fish, and does not alter the physical appearance of the fish.

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Url:https://www.ncbi.nlm.nih.gov/books/NBK482511/

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