Precautions
Be sure to tell your physician that you're taking Zyvox before having any type of surgery, including a dental procedure. This medicine will only treat bacterial infections. It won't work for colds, the flu, or any other viral infections. Antibiotics may cause diarrhea.
What should I know about Zyvox before taking it?
Dosage Guidelines for ZYVOX Neonates less than 7 days: Most pre-term neonates less than 7 days of age (gestational age less than 34 weeks) have lower systemic linezolid clearance values and larger AUC values than many full-term neonates and older infants. These neonates should be initiated with a dosing regimen of 10 mg/kg every 12 hours.
How often do you give Zyvox to newborns?
Get emergency medical help if you have signs of an allergic reaction to Zyvox (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Call your doctor at once if you have:
When should I get emergency medical help if I'm allergic to Zyvox?
ZYVOX I.V. Injection: 200 mg/100 mL (2 mg/mL) and 600 mg/300 mL (2 mg/mL) linezolid single-dose, ready-to-use flexible plastic infusion bags in a foil laminate overwrap. ZYVOX 600 mg... Did you find an answer to your question?
How many milligrams of Zyvox are in a single dose?
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How long does it take to administer zyvox?
ZYVOX I.V. Injection should be administered by intravenous infusion over a period of 30 to 120 minutes. Do not use this intravenous infusion bag in series connections. Additives should not be introduced into this solution. If ZYVOX I.V. Injection is to be given concomitantly with another drug, each drug should be given separately in accordance with the recommended dosage and route of administration for each product. Discard unused portion.
What is Zyvox used for?
ZYVOX is indicated for the treatment of nosocomial pneumonia caused by Staphylococcus aureus...
How to use Zyvox suspension?
ZYVOX for Oral Suspension is supplied as a powder/granule for constitution. Gently tap bottle to loosen powder. Add a total of 123 mL distilled water in two portions. After adding the first half, shake vigorously to wet all of the powder. Then add the second half of the water and shake vigorously to obtain a uniform suspension. After constitution, each 5 mL of the suspension contains 100 mg of linezolid. Before using, gently mix by inverting the bottle 3 to 5 times. Do not shake. Store constituted suspension at room temperature. Use within 21 days after constitution.
What is the name of the drug Zyvox?
ZYVOX I.V. Injection, ZYVOX Tablets, and ZYVOX for Oral Suspension contain linezolid, which is a synthetic antibacterial agent of the oxazolidinone class. The chemical name for linezolid is (S)-N- [ [3- [3-Fluoro...
How long does it take for a preterm neonate to get linezolid?
Neonates less than 7 days: Most pre-term neonates less than 7 days of age (gestational age less than 34 weeks) have lower systemic linezolid clearance values and larger AUC values than many full-term neonates and older infants. These neonates should be initiated with a dosing regimen of 10 mg/kg every 12 hours.
How to report a drug to the FDA?
You may also report to the U.S. Food and Drug Administration (FDA) by visiting www.fda.gov/medwatch or by calling the U.S. FDA at (800)-332-1088.
Does hemodialysis help with linezolid?
In the event of overdosage, supportive care is advised, with maintenance of glomerular filtration. Hemodialysis may facilitate more rapid elimination of linezolid. In a Phase 1 clinical trial, approximately 30...
Very Important
A change in your diet, medicine, or dosage may be necessary. Promptly consult your doctor or pharmacist.
Are you currently using Zyvox?
This survey is being conducted by the WebMD marketing sciences department.
What is zyvox used for?
Facts about Linezolid (Zyvox) Used to treat infections, including pneumonia, infections of the skin, and infections caused by a resistant bacterium (Enterococcus faecium). Is a reversible monoamine oxidase inhibitor (MAOI). Although the exact mechanism of this drug interaction is unknown, linezolid inhibits the action of monoamine oxidase A—an ...
How long after linezolid can you stop Prozac?
Most serotonergic psychiatric drugs should be stopped at least 2 weeks in advance of linezolid treatment. Fluoxetine (Prozac), which has a longer half-life compared to similar drugs, should be stopped at least 5 weeks in advance. Treatment with the serotonergic psychiatric medication may be resumed 24 hours after the last dose of linezolid.
How long after linezolid is it safe to take a serotonin med?
Treatment with the serotonergic psychiatric medication may be resumed 24 hours after the last dose of linezolid.
What is Linezolid used for?
Linezolid is used to treat infections such as nosocomial pneumonia and complicated skin and skin structure infections, including cases caused by methicillin-resistant Staphylococcus aureus (MRSA). Safety information about this potential drug interaction and important drug usage recommendations for emergency and non-emergency situations are being ...
Where to report adverse events on linezolid?
Report adverse events involving linezolid or serotonergic psychiatric medications to the FDA MedWatch program, using the information in the "Contact Us" box at the bottom of the page.
When should you stop linezolid?
Most serotonergic psychiatric drugs should be stopped at least 2 weeks in advance of linezolid treatment.
Is linezolid a life threatening medication?
In emergency situations requiring life-threatening or urgent treatment with linezolid ( as described above), the availability of alternative interventions should be considered and the benefit of linezolid treatment should be weighed against the risk of serotonin toxicity.
Can you use oral suspension if you have problems breaking down amino acids?
Avoid using the oral suspension formulation if you have problems breaking down amino acids as it contains about 20 mg of phenylalanine (an essential amino acid (a building block for proteins in the body, meaning the body needs it for health but cannot make it. You have to get it from food)
Can you take Zyvox with other drugs?
If Zyvox is taken with certain food and other drugs, the effects of either could be increased , decreased, or altered. It is especially important to check with your doctor before combining Zyvox with the following: buspirone, dopamine, dobutamine, epinephrine, isocarboxazid, meperidine, norephinephrine, phenylpropanolamine, phenelzine, pseudoephedrine, serotonin 5-HT1 receptor antagonists (such as sumatriptan, zolmitriptan), serotonin reuptake inhibitors (such as citalopram, fluoxetine, paroxetine), tricyclic antidepressants, tyramine.
Is zyvox an antibiotic?
Zyvox (linezolid) is not a commonly used antibiotic, but not necessarily because the drug is unsafe. In fact, Zyvox is an extremely effective antibiotic that is used to cure resistant microbial infections including:
Is Zyvox a resistant drug?
Unfortunately, there have been confirmed reports that Zyvox resistant organisms are occurring at various health care locations. Inappropriate and overuse of the drug has led to an increase in resistant organisms and generally, alternative treatments are to be considered prior to using Zyvox, especially in an outpatient setting.
What is Linezolid used for?
LINEZOLID (li NE zoh lid) is an oxazolidinone antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.
Can you take Linezolid with MAO?
Taking these beverages along with Linezolid might increase the risk of serious high blood pressure, confusion, restlessness, or other side effects. · Notes for Professionals: Linezolid is an antibiotic that is also a reversible, non-selective inhibitor of MAO.
Can you take tyramine with linezolid?
· Notes for Consumers: Certain foods containing tyramine might increase the risk of side effects with Linezolid. You should probably limit your intake of alcoholic beverages, aged or smoked meats (like sausages or smoked or pickled fish), aged cheeses, and caffeine containing foods like coffee, colas, teas, and chocolate while on Linezolid. Taking these foods along with Linezolid might increase the risk of increased blood pressure, confusion, restlessness, or other side effects. Ask your dietician or health care professional for a complete listing of foods best avoided while on Linezolid.
Is chocolate safe to eat with linezolid?
Chocolate is usually safe in small servings, but according to the Micromedex database, large amounts can contain tyramine. Because there are no studies specifically regarding chocolate and linezolid, ask your doctor for her guidance on consuming chocolate while you are taking linezolid 1.
Can you take tyramine with linezolid?
Linezolid is a powerful antibiotic that can sometimes cause an elevation in blood pressure 1. Because of this, it is important that you avoid foods that contain tyramine; foods containing tyramine can also elevate your blood pressure, leading to a potentially serious reaction. When your doctor prescribes linezolid (Zyvox), she should give you a list of foods to avoid 1. People who have migraine headaches or take certain blood pressure medications called MAO inhibitors have similar dietary restrictions; fortunately, the Micromedex drug database contains extensive information about foods containing tyramine. Contact your doctor if you have questions about any foods.
How to use zyvox?
Use Zyvox (Linezolid (Oral/Injection)) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
What is zyvox used for?
Zyvox (Linezolid (Oral/Injection)) Linezolid is an antibiotic that fights bacteria in the body. Linezolid is also an MAO (monoamine oxidase) inhibitor. Linezolid is used to treat different types of bacterial infections, such as pneumonia, skin infections, and infections that are resistant to other antibiotics.
How long can you keep linezolid?
Store all forms of linezolid at room temperature away from moisture, heat, and light. Do not freeze. Throw away any liquid not used within 21 days.
What to do if someone overdoses on zyvox?
If you think you or someone else may have overdosed on: Zyvox (Linezolid (Oral/Injection)) , call your doctor or the Poison Control center. (800) 222-1222. If someone collapses or isn't breathing after taking Zyvox (Linezolid (Oral/Injection)), call 911. 911.
Where is Linezolid given?
Linezolid injection is given in a vein.
Can you take Linezolid if you are allergic to it?
You should not use linezolid if you are allergic to it. Do not use linezolid if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, methylene blue injection, phenelzine, rasagiline, selegiline, and tranylcypromine. if you use a catheter.
Can you take tyramine with linezolid?
If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine. Eating tyramine while you are using linezolid can raise your blood pressure to dangerous levels.
