
Full Answer
When to give hypotonic fluid?
What You Need to Know About Using Colloid Solutions:
- Risk for fluid volume overload – watch for signs and symptoms
- Use 18-gauge needles when administering colloid solutions
- Can cause increased bleeding time
When is hypotonic solution used?
Hypotonic solutions are used when the cell is dehydrated and fluids need to be put back intracellularly. This happens when patients develop diabetic ketoacidosis (DKA) or hyperosmolar hyperglycemia. Important: Watch out for depleting the circulatory system of fluid since you are trying to push extracellular fluid into the cell to re-hydrate it.
When are hypertonic solutions used?
- Document baseline data. Before infusion, assess the patient’s vital signs, edema status, lung sounds, and heart sounds. ...
- Watch for signs of hypervolemia. ...
- Monitor and observe the patient during administration. ...
- Verify order. ...
- Assess health history. ...
- Prevent fluid overload. ...
- Do not administer peripherally. ...
- Monitor blood glucose closely. ...
What is the difference between isotonic and hypotonic?
- Isotonic -The osmotic pressure outside the cells is the same as the osmotic pressure inside the cells.
- A hypotonic solution will have a lower concentration of solutes than the cell. ...
- A hypertonic solution will have a higher concentration of solutes than the cell and will have a higher osmotic pressure outside the cell than inside the cell.

Is parenteral nutrition hypertonic?
Solutions for peripheral parenteral nutrition are hypertonic to blood, and their osmolality should not exceed 900 mOsm/L.
Why is TPN hypotonic?
Although TPN/PPN and fluids containing 5% dextrose are iso/hyperosmolar, they are effectively hypotonic because the dextrose is rapidly metabolized. The aforementioned solutions containing 20–40mEq/L of KCl were also considered hypotonic.
Are TPN solution hypertonic?
TPN and PPN (total parenteral nutrition and partial parenteral nutrition) are hypertonic. Other than that, I know that greater than or equal to 5% Dextrose is considered hypertonic (D5NS, D5LR, D10). Albumin and highly concentrated electrolytes (Potassium, Magnesium), and also blood products, are hypertonic.
What happens if you give TPN too fast?
The rate at which TPN is administered to a baby is crucial: if infused too fast there is a risk of fluid overload, potentially leading to coagulopathy, liver damage and impaired pulmonary function as a result of fat overload syndrome.
Does TPN provide hydration?
TPN is beneficial because it provides nutrients that are vital in maintaining high energy, hydration and strength levels.
What is the main difference between PPN and TPN?
There are two primary types of PN, peripheral parenteral nutrition (PPN) and total parenteral nutrition (TPN). As the names imply, PPN is generally used for patients who need supplementary nutrition, while TPN is for patients who require all of their dietary needs replaced.
Is TPN a hyperosmolar?
Total parenteral nutrition (TPN) is a hyperosmolar glucose-containing lipid emulsion that provides an ideal medium in which bacteria can thrive. Much of the evidence regarding the administration of TPN through CVCs dates from the 1970s and 1980s and is well established.
What is in hypertonic solution?
Hypertonic solution: A solution that contains more dissolved particles (such as salt and other electrolytes) than is found in normal cells and blood.
Can you hang TPN with normal saline?
TPN is not compatible with any other type of IV solution or medication and must be administered by itself. TPN must be administered using an EID (IV pump), and requires special IV filter tubing (see Figure 8.10) for the amino acids and lipid emulsion to reduce the risk of particles entering the patient.
Why is TPN given through a central line?
Historically, total parenteral nutrition (TPN) has been administered by the central venous route because of the rapid development of thrombophlebitis when TPN solutions are administered into peripheral veins.
Why do you taper TPN?
TPN is usually slowed or discontinued prior to anesthesia, primarily to avoid complications from excessive (hyperosmolarity) or rapid decrease (hypoglycemia) in infusion rates in the busy operative arena. That said, because abrupt discontinuance may lead to severe hypoglycemia, TPN must be turned down gradually.
Can TPN cause fluid overload?
A physician may order a total fluid intake (TFI) for the amount of fluid to be infused per hour to prevent fluid overload in patients receiving TPN. It is important to keep track of all the fluids infusing (IV fluids, IV medications, and TPN) in order to avoid fluid overload (Perry et al., 2014).
What is a hypertonic solution?
In other words, a hypertonic solution is one in which there is a greater concentration or number of solute particles outside a membrane than there are inside it.
What are some examples of hypertonic cells?
Hypertonic Example. Red blood cells are the classic example used to explain tonicity. When the concentration of salts (ions) is the same inside the blood cell as outside of it, the solution is isotonic with respect to the cells, and they assume their normal shape and size. If there are fewer solutes outside the cell than inside it, ...
How does water move in hypertonic solutions?
Movement of Water in Hypertonic Solutions. Water moves across a semipermeable membrane. Remember, water moves to equalize the concentration of solute particles. If the solutions on either side of the membrane are isotonic, water moves freely back and forth.
Why is salt water hypertonic?
It's also a problem if you drink too much water . If there is a higher concentration of solutes outside of the cell than inside it, such as would happen if you placed red blood cells in a concentrated salt solution, then the salt solution is hypertonic with respect to the inside of the cells . The red blood cells undergo crenation, which means they ...
Is salt water hypertonic or hypotonic?
But, if you view the situation from the inside of the cell, you could consider the plasma to be hypotonic with respect to the saltwater.
Is each side of a partition isotonic?
Each side of the partition is isotonic with respect to the other if you consider there are 4 moles of ions on each side. However, the side with sodium ions is hypertonic with respect to that type of ions (another side is hypotonic for sodium ions). The side with the potassium ions is hypertonic with respect to potassium ...
What is TPN electrolyte?
TPN Electrolytes (multiple electrolyte additive) is indicated for use as a supplement to nutritional solutions containing concentrated dextrose and amino acids delivered by central venous infusion, to help maintain electrolyte homeostasis in adult patients.
What is the pH of TPN?
It contains no phosphate and no bacteriostat, antimicrobial agent or added buffer. The pH is 6.6 (6.0 to 7.5).
How much potassium is needed for TPN?
TPN patients usually require 30 to 50 mEq of potassium per liter of TPN solution containing concentrated (20—25%) dextrose.
Is TPN a multi-additional electrolyte?
TPN Electrolytes (multiple electrolyte additive) is contraindicated in pathological conditions where additives of potassium, sodium, calcium, magnesium or chloride could be clinically deleterious, e.g., anuria, hyperkalemia, heart block or myocardial damage and severe edema due to cardiovascular, renal or hepatic failure.
Can you add TPN to amino acids?
Alternatively, the TPN Electrolytes can be added to the bottle of amino acids or concentrated dextrose, to permit addition of the necessary phosphate additive to the remaining bottle. This latter technique helps avoid physical incompatibilities between calcium and phosphorus.
Can TPN electrolytes affect reproduction?
Animal reproduction studies have not been conducted with TPN Electrolytes. It is also not known whether TPN Electrolytes can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. TPN Electrolytes should be given to a pregnant woman only if clearly needed.
What happens when an egg is placed in a hypertonic solution?
The permeable membranes (aka eggs) that were in the Isotonic and Hypotonic solutions only had a very minor size difference…but the egg placed in the hypertonic solution shows a drastic change! The water has been sucked out into the hypertonic solution via osmos is, causing a very serious case of egg-dehydration.
Is IV solution hypertonic?
Seriously though, in nursing, we’re always comparing solutions to the human body! So when we say that an IV solution is Hypertonic, what we are really saying is that it has a higher solute to solvent ratio than blood does. Blood basically becomes our definition of what “Isotonic” means, but that article will come later this week.
