Precautions
Apr 28, 2020 · Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID). NSAIDs may increase your risk of heart attack, heart failure, or stroke. This risk may be higher if you're taking it long term, at high doses, or if you already have heart problems or risk factors for heart disease, such as high blood pressure.
Is it safe to drink alcohol while taking Indocin?
Oct 12, 2020 · Indomethacin may harm your kidneys if you take it for a long time. Call your doctor if you have symptoms of kidney damage, such as: …
Is Indomethacin a pain killer?
The long-term tolerability and efficacy of indomethacin were evaluated in a retrospective study of 67 patients with moderate to severe rheumatoid arthritis, osteoarthritis, or ankylosing spondylitis who took the drug daily for periods ranging from three to 20 years. Only patients who had not experienced side effects during the first ten to 14 days of indomethacin therapy were included.
Does indomethacin Make you Sleepy?
istration of indomethacin. In fact, indomethacin com-pletely prevente th incremented isn PR (froAm 1.0 ± 0.2 to 1.5 ± 0.3 ng angiotensin I/ml/hr,p>0.5) and PA (from 1.2 ±0.2 to 3.4 ± 1.0 ng/dl, p>0.5) after ambulation while the intake of sodium was nor-mal. Prolonged treatment with indomethacin failed to prevent completel th increasey ien ...
Will indomethacin pills cause weight gain?
Taking high doses of indomethacin (Indocin) or taking it for a long time can cause heart problems. It is not recommended to take indomethacin (Indocin) if you have a history of heart problems like heart attacks or strokes, and you should never use indomethacin (Indocin) right before or after heart bypass surgery.
How long is it safe to take indomethacin?
Can indomethacin be used long term?
Is indomethacin hard on the kidneys?
Is indomethacin high risk?
What does indomethacin do to your body?
What can I take instead of indomethacin?
- Naproxen.
- Indocin.
- Ibuprofen.
- Advil.
- Methylprednisolone.
- Aleve.
Can indomethacin cause liver damage?
Which is better indomethacin or diclofenac?
Can you drink alcohol while taking indomethacin?
It's safest to avoid alcohol altogether while you're taking Indoin. If you do drink alcohol while you're on Indocin, you can increase your risk of internal bleeding.Feb 5, 2021
Does indomethacin make you gain weight?
How long does indomethacin 50 mg stay in your system?
Is indomethacin safe for older adults?
Does indomethacin go away?
Some side effects of indomethacin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Does indomethacin cause side effects?
Side effects requiring immediate medical attention. Along with its needed effects, indomethacin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention .
Can NSAIDs cause bleeding?
NSAIDs cause an increased risk of serious gastrointestinal adverse events, including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal events.
Can NSAIDs cause stroke?
NSAIDs cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use. Indomethacin is contraindicated in the setting of CABG surgery.
Does renal dysfunction occur more frequently during IV use?
In controlled clinical trials, renal dysfunction occurred statistically significantly more frequently during IV use in neonates than in those treated with place bo. Renal dysfunction has been reported in 41% of neonates and included at least 1 of the following: reduced urinary output, reduced urine sodium, chloride, or potassium; reduced urine osmolality, free water clearance, or GFR; elevated serum creatinine or BUN; or uremia. [ Ref]
What causes a swollen eye?
increased hunger. increased sweating. increased thirst. increased urination. irregular breathing. irritation and swelling of the eye. jerky movements of the head, face, mouth, and neck. joint pain. large, flat, blue or purplish patches in the skin.
How long does it take for a syringe to work?
This medicine usually begins to work within 1 week, but in severe cases up to two weeks or even longer may pass before you begin to feel better. Also, several weeks may pass before you feel the full effects of this medicine. Swallow the capsule whole. Do not open, crush, break, or chew it.
How to store a med?
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Ask your healthcare professional how you should dispose of any medicine you do not use.
What to do if you miss a dose of a sulfate sulfate?
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Can indomethacin be used for elderly?
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of indomethacin in the elderly. However, elderly patients may be more sensitive to the effects of indomethacin than younger adults, and are more likely to have unwanted side effects (eg, confusion, psychosis) and age-related kidney or stomach problems, which may require caution and an adjustment in the dose for patients receiving indomethacin.
Does Indomethacin help with arthritis?
However, this medicine does not cure arthri tis and will help you only as long as you continue to take it.
Can medicine cause side effects?
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur:
Can NSAIDs cause stroke?
NSAIDs cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use. Indomethacin is contraindicated in the setting of CABG surgery. NSAIDs cause an increased risk of serious gastrointestinal adverse events, including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal events .
What is Indomethacin used for?
Indomethacin (Indocin) is used to treat moderate to severe pain, swelling, tenderness, and stiffness caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It can also be used for gout attacks and shoulder busitis or tendonitis.
Can you take two different meds together?
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
What are the side effects of a heart attack?
Pain that radiates up to your shoulder, arm, neck , or jaw (signs of a heart attack) Sudden trouble talking, trouble walking, or numbness on one side of your body or face (signs of a stroke) The following side effects may get better over time as your body gets used to the medication.
Why do doctors prescribe indometacin?
If you need to take indometacin for a long time, your doctor may want to prescribe another medicine along with it to protect your stomach from irritation.
Is indometacin a NSAID?
Indometacin for pain and inflammation. Indometacin is a medicine called a non-steroidal anti-inflammatory drug. It is also known as 'an NSAID'. Before you take indometacin, let your doctor know if you have ever had a bad reaction to any other anti-inflammatory painkiller.
What is the purpose of Indometacin?
Indometacin is used to treat painful conditions such as arthritis, sprains and strains, back pain, period (menstrual) pain, and gout pain. Indometacin works by blocking the effect of chemicals in your body, called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins.
Can you take more than the prescribed dose of a sulfate?
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
Can medicine cause side effects?
Side Effects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur:
What are the symptoms of overdose?
Symptoms of overdose. Confusion about identity, place, and time. severe headache. unusual drowsiness, dullness, or feeling of sluggishness. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
What are the symptoms of a burning stomach?
blue lips and fingernails. blurred vision. breast enlargement and tenderness. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings. burning upper abdominal or stomach pain. canker sores. change in consciousness. change in hearing. chest pain, discomfort, or burning.
What causes a swollen eye?
increased hunger. increased sweating. increased thirst. increased urination. irregular breathing. irritation and swelling of the eye. jerky movements of the head, face, mouth, and neck. joint pain. large, flat, blue or purplish patches in the skin.
What does it mean when you have a purple spot on your face?
pale skin. persistent bleeding or oozing from puncture sites, mouth, or nose. personality changes. pinpoint red or purple spots on the skin. pounding in the ears. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. red skin lesions, often with a purple center. red, irritated eyes.
How It Works
Indomethacin is used to relieve pain, swelling, and joint stiffness caused by arthritis, gout, bursitis, and tendonitis.
May Treat: Gout · Acute shoulder pain due to bursitis · Acute shoulder pain due to tendonitis · Ankylosing spondylitis · Bursitis and more
Brand Names: Indocin · Indocin SR · Bene-Cin · Indameth · Indo-Lemmon and more
Drug Class: NSAID Analgesics, (COX Non-Specific) - Indole Acetic Acid Derivatives
Availability: Prescription Required
Pregnancy: Do not use. This medication may be harmful to an unborn child.
May Treat: Gout · Acute shoulder pain due to bursitis · Acute shoulder pain due to tendonitis · Ankylosing spondylitis · Bursitis and more
Brand Names: Indocin · Indocin SR · Bene-Cin · Indameth · Indo-Lemmon and more
Drug Class: NSAID Analgesics, (COX Non-Specific) - Indole Acetic Acid Derivatives
Availability: Prescription Required
Pregnancy: Do not use. This medication may be harmful to an unborn child.
Lactation: Consult a doctor before using
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution
- Watch for bleeding, heart attack or stroke signs.
- Avoid use in pregnancy from 20 weeks until birth
- May make you drowsy or dizzy. Drive with caution
- Watch for bleeding, heart attack or stroke signs.
- Avoid use in pregnancy from 20 weeks until birth
- May make you drowsy or dizzy. Drive with caution
- Limit alcohol consumption and stop using tobacco.
- Low dose daily aspirin ok Ask MD about other NSAIDs
- For capsule products : Important to read patient package insert& med guide. Best to take with food to lessen stomach upset. Swallow with 8 oz water. Do not lie down for 10min.
- For capsule, extended release products : Before use, important to read the Medication Guide. Swallow whole with water. Do not lie down for 10min.
- For suppository, rectal products : Do not hold in hand too long.Suppository may melt. Tell doctor your complete medical history.
- For suspension, oral products : Shake well & measure with dosing spoon/cup/syringe.
Upsides
Downsides
Bottom Line
Tips
Response and Effectiveness
Interactions
Further Information
in Summary
For The Consumer
For Healthcare Professionals
- Medicines that interact with indomethacin may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with indomethacin. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about ho...
Frequently Asked Questions
Further Information
