
What are the side effects of depressants?
Some long-term effects of CNS depressants on the body include:
- Addiction
- Chronic fatigue
- Weight gain
- Sexual dysfunction and decreased libido
- Respiratory problems
- Difficulties sleeping
- Depression
- Suicidal thoughts and behavior
How do drugs affect the brain and central nervous system?
Your Brain And Drugs Misuse or long-term abuse of drugs can profoundly impact the way your brain functions. Drugs can do this because once ingested, they alter the brain's chemistry in order to slow down or speed up the central nervous system. The central nervous system consists of both your brain and your spinal cord.
What do drugs cause depressants?
Depression of the central nervous system is generally caused by the use of depressant drugs such as ethanol, opioids, barbiturates, benzodiazepines, general anesthetics, and anticonvulsants such as pregabalin used to treat epilepsy. What is CNS toxicity? Central nervous system toxicity manifests initially as anxiety, dizziness, circumoral numbness, lightheadedness, and tinnitus.
What are some examples of depressants?
What are prescription CNS depressants?
- diazepam (Valium ®)
- clonazepam (Klonopin ®)
- alprazolam (Xanax ®)
- triazolam (Halcion ®)
- estazolam (Prosom ®)

How do CNS stimulants work?
CNS stimulants work by blocking the reuptake of norepinephrine and dopamine in the brain. They may also directly increase the release of these neurotransmitters in the brain. Norepinephrine and dopamine are believed to be involved with different physical and mental processes like attention, mood, and motivation.
What are examples of CNS depressants?
Understanding CNS DepressantsDiazepam (Valium)Clonazepam (Klonopin)Alprazolam (Xanax)Triazolam (Halcion)Estazolam (Prosom)
What happens in CNS depression?
CNS depression occurs when a person's central nervous system has slowed down, causing a slower heart rate and slower breathing. CNS depressant medications work to depress the central nervous system, which slows down brain activity and causes your muscles to relax.
Why are CNS depressants addictive?
The Side Effects While Using CNS Depressant Drugs Even when individuals use depressant drugs responsibly and at proper doses, negative effects and depressant addiction can occur. This is because the objective of these drugs is to inhibit sensations and feelings by slowing activity in the brain.
How do CNS depressants affect the brain?
How do CNS depressants affect the brain? Most CNS depressants act on the brain by increasing activity of gamma-aminobutyric acid (GABA), a chemical that inhibits brain activity. This action causes the drowsy and calming effects that make the medicine effective for anxiety and sleep disorders.
What are signs of CNS depression?
Symptoms of severe CNS depression include:reduced heart rate.low breathing rate of fewer than 10 breaths per minute.extreme confusion or memory loss.nausea and vomiting.poor judgment.blue lips or fingertips.irritability and aggression.clammy or cold skin.More items...
Is caffeine a CNS depressant?
Caffeine is classified as a central nervous system (CNS) stimulant and an organic molecule called methylxanthine. Caffeine has three notable mechanisms of action on the CNS that produce a psychostimulant effect.
Is Xanax a CNS depressant?
Xanax is a prescription central nervous system (CNS) depressant. CNS depressants include sedatives, tranquilizers, and hypnotics that slow brain activity. They are prescribed to treat anxiety, panic, acute stress reactions, and sleep disorders.
Is vodka a central nervous system depressants?
Abstract. Introduction: alcohol is a psychotropic depressant of the central nervous system (CNS) that promotes simultaneous changes in several neuronal pathways, exerting a profound neurological impact that leads to various behavioral and biological alterations.
Is Gabapentin a CNS depressant?
Our evaluation shows that the use of these medicines, often referred to as gabapentinoids, has been growing for prescribed medical use, as well as misuse and abuse. Gabapentinoids are often being combined with CNS depressants, which increases the risk of respiratory depression.
What is a drug that calms you down?
Benzodiazepines (also known as tranquilizers) are the most widely prescribed type of medication for anxiety. Drugs such as Xanax (alprazolam), Klonopin (clonazepam), Valium (diazepam), and Ativan (lorazepam) work quickly, typically bringing relief within 30 minutes to an hour.
Is Zoloft a CNS depressant?
(1) Central Nervous System (CNS) Depressants Examples of CNS depressants include alcohol, barbiturates, anti-anxiety tranquilizers (e.g., Valium, Librium, Xanax, Prozac, and Thorazine), GHB (gamma hydroxybutyrate), Rohypnol, and many other anti-depressants (e.g., Zoloft, Paxil).
Is Xanax a CNS depressant?
Xanax is a prescription central nervous system (CNS) depressant. CNS depressants include sedatives, tranquilizers, and hypnotics that slow brain activity. They are prescribed to treat anxiety, panic, acute stress reactions, and sleep disorders.
What are examples of CNS stimulants?
OVERVIEW. Central nervous system stimulants used for attention deficit disorder, narcolepsy or excessive sleepiness include the amphetamines, methylphenidate, atomoxetine, modafinil, armodafinil, pitolisant and solriamfetol.
Is Benadryl a CNS depressant?
The CNS depressant effect of diphenhydramine parallels its plasma concentrations. The plasma concentration threshold for sedation is 30 to 42 ng/mL, and to cause mental impairment is 58 to 74 ng/mL.
Is caffeine a CNS depressant?
Caffeine is classified as a central nervous system (CNS) stimulant and an organic molecule called methylxanthine. Caffeine has three notable mechanisms of action on the CNS that produce a psychostimulant effect.
How do depressants affect the brain?
CNS depressants act on the brain by affecting the GABA neurotransmitter. GABA stands for gamma aminobutyric acid. GABA slows down brain activity. So, when it is activated by a particular CNS depressant, a sense of calm and relaxation will be felt. Various CNS depressants act on this neurotransmitter in their own unique way. But, whatever the case may be, all CNS depressants will have the same effect of relaxing the brain.
How do neurotransmitters work?
Neuro-transmitters work by sending messages between various cells in the brain. The brain has many different types of neurotransmitters for various functions. For instance, the transmitter dopamine works to provide pleasure in the midbrain area. Whereas, GABA is another neurotransmitter that helps to relax brain activity.
What are the chemicals in the CNS?
By doing so, they help to relax and calm people who use them. They include barbiturates, benzodiazepines, alcohol, and some tranquillisers to name a few. In high doses, they can become anaesthetics. CNS depressants can be harmful if used against prescription or abused.
What is a barbiturate?
Barbiturates, such as mephobarbital (Mebaral) and pentobarbital sodium (Nembutal) are prescribed medicines. These medications tend to treat sleeping disorders, anxiety, and tension.
Can pain meds be combined?
This includes over-the counter or OTC allergy, cold, and pain meds. If combined, it can be fatal. It's because these OTC drugs and CNS depressants lower brain activity simultaneously, when combined.
Can you get addicted to CNS depressants?
Potential AddictionIt's important to get treatment if one has abused or is dependent on CNS depressants. Due to its lulling effect, people do get hooked on these medications. And because it is not considered illegal, it's easy to dismiss such dependency as addiction. Nevertheless, any substance where there is a need to use it for normal functioning, has crossed the line into addiction. Especially, if such use continues unabated in spite of the risks involved in overdose. Examples of the risks of overdose include but are not limited to the following: Coma, Unconsciousness, and Death. Yet, besides the effects of the drug, we have to also consider the effects of an addiction, which may include: Isolation, Obsession, and Compulsive use. As there is potential for addiction, one can get help for CNS depressant abuse. What's important is to get into hospital for detoxification. Be honest about the amount, frequency, and type of drug used. Then, after some time in detoxification, you can then proceed for addiction treatment, if necessary. Some people may just have a problem with the drugs, but not have an addiction to it. But, if it has created an unmanageable life, addiction treatment will help in the long-run. These involve counselling, therapies, and behavioural management around relapse prevention. For more information, call us. We'll be more than happy to help you in your recovery from CNS depressants.
Can CNS depressants cause sleepiness?
For instance, they should not be applied with any medicine that causes sleepiness or reduces pain.
What is the CNS depressant?
CNS depressants are medications and other substances that slow down the CNS. Many CNS depressants work by increasing the activity of the neurotransmitter gamma-aminobutyric acid (GABA), a chemical that prevents or slows the delivery of messages between cells.
What are some examples of CNS depressants?
These substances are called CNS depressants. Examples of CNS depressants include tranquilizers, hypnotics, and sedatives. In recent years, doctors have prescribed opioid painkillers for many conditions, but overuse of these drugs can lead to problems. People also use them as recreational drugs.
How do opiates and opioids work?
Both opiates and opioids work by interfering with the CNS and blocking pain signals to the brain.
What are the symptoms of CNS depression?
Severe symptoms of CNS depression include loss of consciousness, coma, and death. Anyone with these symptoms needs immediate medical help. Treatment for CNS depression or CNS depressant overdose depends on the substances involved. Some CNS drugs have antidotes that can reverse their effects.
What are the factors that affect the impact of CNS depression?
Factors that affect the impact of CNS depression include: the cause. the type and dose of a substance. the severity of the illness or injury. the size of the individual. the person’s medical history.
What causes depression in the body?
Central nervous system — or CNS — depression happens when the body’s normal neurological functions slow down. It can result from substance overdoses, poisoning, or other medical conditions.
How does the brain control the heart?
It controls most bodily functions — including breathing and the heart — by sending messages between the brain and other nerves via the spinal cord. It plays a role in essential bodily processes: Involuntary processes: These do not need conscious thought. They regulate vital organs such as the heart, lungs, and stomach.
What is a CNS depressant?
Understanding CNS Depressants. CNS depressants are an overarching category of medications that include sedatives, tranquilizers, and hypnotics. Each type of CNS depressant has a different medical use depending on your health needs. Your doctor may give you a CNS depressant prescription to help with a variety of different conditions.
What happens if you become dependent on a depressant?
Substance abuse disorder. If you become dependent on your CNS depressant medication, it can lead you down the path of addiction. You may seek an even better feeling than your medication can provide, taking more than your doctor prescribed or mixing it with alcohol or other drugs. .
What is a non-benzodiazepine hypnotic?
. Non-Benzodiazepine Sedative Hypnotics include: These medications are prescribed in the form of a pill, capsule, or liquid that you take orally.
What is the name of the medication that slows the brain down?
If you suffer from insomnia, anxiety, panic attacks, or seizures, your doctor may prescribe a class of drugs called central nervous system (CNS) depressants. These medications are designed to slow your brain down, relax your muscles, and provide a sense of calm.
How does pentobarbital work?
They work by increasing your brain’s production of a chemical called gamma-aminobutyric acid (GABA). This chemical limits brain activity.
Can you take a CNS depressant long term?
If you need to take a CNS depressant medication long-term, you may need to increase your dose to continue benefiting from it . Over time, your body can get used to the effects of the medication, leading to the need for a higher dose to experience the same effects.. Increasing your dose may lead to a feeling of dependence or addition to ...
Can you overdose on a CNS depressant?
Taking too much of a CNS depressant can lead to an overdose. If you have signs of an overdose, like your ability to breathe slows or stops, seek immediate medical attention. A CNS overdose may lead to: Hypoxia, or a lack of oxygen to your brain. Seizures.
What is the chemical that causes depression in the CNS?
A variety of other things in your environment can lead to CNS depression when ingested or inhaled. One such product is ethylene glycol, a chemical found in a variety of consumer goods, including antifreeze and de-icing products. When ingested, this chemical is toxic to the CNS, kidneys, and heart. It can cause serious health complications, including death.
How to diagnose CNS depression?
To determine the cause of your CNS depression, your doctor will probably order a series of blood and urine tests. In many cases, they may also order a CT scan or MRI of the brain. Once your CNS is back on track, you’ll need to address the source of the problem.
How to lower the chances of depression due to substances?
To lower the chances of CNS depression due to substances, follow these tips: Tell your doctor about other medications you take and any other medical conditions you have, including problems with addiction. Follow directions for taking your medications.
What is it called when the brain slows down?
The spinal cord handles nerve impulses, allowing your brain to communicate with the rest of your body. When CNS functions slow down, it’s called CNS depression. Slowing down a little isn’t necessarily dangerous. In fact, sometimes it’s even helpful. But if it slows down too much, it can quickly become a life-threatening event.
What are opiates prescribed for?
These are usually prescribed for pain. Common opiates include:
How does a drug affect your heart?
Certain drugs affect the neurotransmitters in your brain, causing brain activity to slow. That, in turn, makes your breathing slower and shallower. It also makes your heart beat slower.
What is the CNS?
The central nervous system (CNS) consists of the brain and the spinal cord.
Common Types of CNS Depressants
Take a look at some of the most commonly used CNS depressant drugs and how they may lead to risks for addiction.
Addiction to Central Nervous System Depressants
If you have a dependence on or addiction to any of these drugs, it’s critical to seek help. You may have an addiction if you:
How do CNS depressants work?
Different classes of CNS depressants work in different ways, but all have the ability to reduce activity in the central nervous system and lower levels of awareness in the brain. While CNS depressants all share this ability, there are significant differences among substances within this drug class. In particular, some are generally considered ...
What is the purpose of central nervous system depressants?
Central nervous system depressants are medications or substances that slow brain activity, making them useful for treating anxiety, panic, and sleep disorders. Start the road to recovery.
How to treat addiction to CNS depressants?
Treatment and Therapies for CNS Depressant Addiction. Treatment for addiction to a central nervous system depressant begins with detox to allow the drugs to exit the system, preferably in rehab or medical facility.
What is a barbiturate?
Barbiturates, or “downers,” are a type of CNS depressant that are prescribed to treat anxiety, tension, and sleep disorders. Common barbiturates include Amytal, Luminal (Phenobarbital), Mebaral, Nembutal, and Seconal.
What are the different types of CNS depressants?
There are three major types of CNS depressants: sedatives, hypnotics, and tranquilizers. Drugs that are classified as CNS depressants include: Different classes of CNS depressants work in different ways, but all have the ability to reduce activity in the central nervous system and lower levels of awareness in the brain.
What is the best medication for anxiety?
Benzodiazepines. Sometimes called “benzos,” benzodiazepines are central nervous system depressants that are prescribed to treat anxiety, sleep disorders, convulsions, and other acute stress reactions. Common benzos include Valium, Xanax, and Ativan. Benzodiazepines are highly effective in treating anxiety and insomnia due to the sleep-inducing, ...
How does alcohol affect the brain?
The degree to which the brain is affected by this central nervous system depressant depends on how much, and how fast, a person drinks. Due to the initial positive behavioral effects of alcohol, many people don’t realize that the substance is a CNS depressant. For example, when someone first begins to drink, he or she may feel less reserved and more relaxed because of the chemical changes alcohol causes within the brain. However, the more someone drinks, the more the brain is affected and the likelihood that a negative emotional response will take over. Alcohol can actually increase anxiety and stress rather than reduce it, and elicit other negative reactions such as anger, aggression, and depression. Chronic alcohol use can also lead to dependence, addiction, and withdrawal symptoms when attempting to stop usage of the drug.
What are depressants and stimulants?
As you would expect from the name, depressants are the opposite of stimulants; they are drugs that reduce CNS activity. Because of this they are sometimes colloquially referred to as “downers,” in contrast to the term “uppers” being used for stimulants. Although there are many different types of depressants, most target the same site of action: the GABA receptor. Therefore, before we discuss any particular drugs, it is worth taking a closer look at this receptor and how different depressants interact with it.
Which receptors cause depolarization?
Both GABAA and GABAB receptor subtypes cause depolarization. What are the two different ways that they achieve this?
Why are barbiturates used as anticonvulsants?
Barbiturates have mostly been replaced with benzodiazepines and Z-drugs for treatment of insomnia and anxiety because they have fewer issues with dependence and overdose. They remain in use as anticonvulsants, general anesthetics, and antagonists to the effects of certain stimulants.
How long do barbiturates last?
Long-acting barbiturates such as phenobarbital have low lipid solubility and are absorbed slowly. In exchange for a delayed onset (about 1 hour), effects can last for up to 12 hours. This makes them useful as anticonvulsants, since fewer doses are required to maintain the drug’s level in the body.
Why are barbiturates used in the treatment of epilepsy?
Barbiturates were routinely used to induce sleep in psychotic patients and were prescribed to treat insomnia and anxiety. They were also shown to reduce the number and intensity of seizures—a first, since no other drugs were effective at treating epilepsy at the time—and began to see use as anticonvulsants.
When were barbiturates used?
Barbiturates are potent sedative-hypnotics that were widely used in the early 1900s. Although their use has declined in recent decades, they remain an illustrative example of how depressants affect neurotransmission. By the end of this section, you should be able to: Explain the history and uses of barbiturates.
What is the main inhibitory neurotransmitter in the brain?
10.1.1 The GABA Receptor. Recall from Chapter 4 that γ-aminobutyric acid (gamma-aminobutyric acid, or GABA for short) is the brain’s main inhibitory neurotransmitter. This is because GABA receptors are inhibitory; in other words, they promote hyperpolarization of the postsynaptic cell. This inhibits the postsynaptic cell from firing ...
