
Precautions
· Levofloxacin may cause a condition that affects the heart rhythm (QT prolongation). Levofloxacin may rarely cause serious changes in blood sugar levels, especially if you have diabetes. Watch for symptoms of high blood …
Does levofloxacin increase the risk of cardiovascular death?
Can levofloxacin cause heart problems? In rare cases, levofloxacin may cause damage to your aorta, the main blood artery of the body. This could lead to dangerous bleeding or death. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back. Which antibiotic is safe for heart patients?
What should I know about levofloxacin before taking it?
· If you have low blood potassium or an abnormally slow heartbeat, levofloxacin may increase your risk of having a fast, slow, or irregular heartbeat, loss of consciousness, or fainting spells. If these symptoms occur, tell your doctor right away.
Is azithromycin and levofloxacin safe for the heart?
For levofloxacin, the increased risk of cardiovascular death was only found in one retrospective study. Therefore, the risks and benefits of antibacterial therapies should be considered when making prescription decisions. This study should not preclude clinicians from avoiding azithromycin and levofloxacin.
Can levofloxacin cause hypoglycemia?
Cleveland Clinic

Which antibiotic is safe for heart patients?
In patients with heart disease, though, azithromycin and other macrolide antibiotics – such as clarithromycin, erythromycin, and telithromycin – can speed up the heart so that it beats very fast, up to 200 times per minute.
Who should not take levofloxacin?
Who should not take LEVOFLOXACIN?diarrhea from an infection with Clostridium difficile bacteria.diabetes.low blood sugar.glucose-6-phosphate dehydrogenase (G6PD) deficiency.low amount of potassium in the blood.a low seizure threshold.pseudotumor cerebri, a condition with high fluid pressure in the brain.More items...
Does levofloxacin increase heart rate?
Levofloxacin infusion increased the heart rate (HR) and prolonged the corrected QT (QTc) intervals significantly (baseline HR: 84.6 +/- 18.8 vs. HR at 60 minutes: 88.6 +/- 18, P = 0.02; baseline QTc: 413.5 +/- 36.9 milliseconds vs.
Can heart failure patients take antibiotics?
In the largest study of its kind to date, researchers found heart patients who took antibiotics had a much lower risk of returning to the hospital due to a heart attack or severe chest pain compared with those who didn't take the infection fighters.
Can levofloxacin increase blood pressure?
Symptoms include pain, burning, tingling, numbness, and weakness. Central nervous system effects. This drug raises your risk of central nervous system (CNS) effects. These can include convulsions, psychosis, and increased pressure inside your head.
What is the most serious side effects of levofloxacin?
Levofloxacin can cause serious side effects, including tendon problems, side effects on your nerves (which may cause permanent nerve damage), serious mood or behavior changes (after just one dose), or low blood sugar (which can lead to coma).
Does Levaquin affect the heart?
The class of antibiotics called fluoroquinolones (Cipro, Levaquin and others) may increase the risk of heart valve problems.
Should I be worried about taking levofloxacin?
Levofloxacin may cause serious liver problems, including hepatitis. Check with your doctor right away if you or your child start having nausea or vomiting, dark urine, light-colored stools, stomach pain, or yellow eyes or skin while using this medicine.
Can Levaquin cause irregular heartbeat?
Antibiotics. Azithromycin (Zithromax) is an antibiotic that may speed up your heart rate. Other antibiotics, such as levofloxacin, amoxicillin, and ciprofloxacin, can change your heart rate, too. It's more likely to happen if you have heart disease.
Are antibiotics safe for heart?
The heart problems occurred about 2 weeks after starting that antibiotic prescription. A rare but serious heart problem can also occur with a type of antibiotics called fluoroquinolones. They can increase the risk of tears in the main artery of the body, called the aorta.
Is azithromycin safe for heart patients?
The study found that azithromycin was associated with an increased risk of cardiovascular death relative to amoxicillin (odds ratio 2.49, 95% confidence interval [CI] 1.38–4.50).
Can antibiotics give you heart palpitations?
Story highlights. A popular antibiotic used to treat bacterial infections can cause abnormal – and possibly fatal – heart rhythms in some patients, according to a new warning from the Food and Drug Administration.
Can you stop taking levofloxacin?
Medicines that interact with levofloxacin may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with levofloxacin. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does.
What are the side effects of taking levofloxacin?
Downsides. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Headache, insomnia, nausea, diarrhea, constipation, and abdominal pain.
How does levofloxacin work?
Levofloxacin works by converting two bacterial enzymes, topoisomerase IV and DNA gyrase, into toxic enzymes that inhibit the manufacture and repair of DNA and other DNA processes, killing the bacteria.
What is the purpose of levofloxacin?
Levofloxacin is an antibiotic that may be used to treat certain bacterial infections. Levofloxacin works by converting two bacterial enzymes, topoisomerase IV and DNA gyrase, into toxic enzymes that inhibit the manufacture and repair of DNA and other DNA processes, killing the bacteria.
Can levofloxacin be used for sinusitis?
However, it is usually only used in the treatment of urinary tract infections, chronic bronchitis, and sinusitis when other alternative treatment options have failed or cannot be used. Levofloxacin may also be used to treat certain types of lung infections.
Does levofloxacin cause headaches?
Tendonitis and tendon rupture, peripheral neuropathy (nerve pain in fingers and toes) and central nervous system effects (side effects that affect the brain including psychosis, convulsions, hallucinations) have been associated with levofloxacin and other fluoroquinolones.
How long after food can you take levofloxacin?
Oral levofloxacin tablets can be administered without regard to food. Take oral levofloxacin solution one hour before or two hours after food. Take levofloxacin at least two hours before or two hours after antacids or preparations containing iron or zinc.
Is ciprofloxacin a risk factor for arrhythmia?
Amoxicillin and ciprofloxacin have shown lower risks. “Usually, arrhythmia is triggered by multiple factors, not just an antibiotic,” says Dr. Nissen. “The risk of a dangerous effect from an antibiotic is highest in people who have heart disease. But everyone should be aware of it.”.
Can antibiotics cause rapid heartbeats?
Certain antibiotics. If you are at high risk for arrhythmia, beware of certain types of antibiotics. Some can disrupt the heart’s electrical activity and lead to a (sometimes lethal) rapid heartbeat.
Is aspirin good for heart disease?
Are they already in your home? Know your risks. If you’re being treated for a heart condition, medicine cabinet staples such as aspirin and ibuprofen may not be good for you. The same goes for certain antibiotics.
Does aspirin cause stent restenosis?
Moreover, those who didn’t take aspirin did not have a higher risk of stent restenosis (re-narrowing of a blood vessel), stroke, heart attack or death than those who did.“All stent patients must take antiplatelet medication to help maximize the success of their procedure. It’s very important,” stresses Dr. Ellis.
What pain relievers are used for atrial fibrillation?
NSAID pain relievers, such as naproxen and ibuprofen. If you have atrial fibrillation (irregular heartbeat) and are on blood thinners to lower your risk of blood clots and stroke, beware of nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs include common pain relievers naproxen (Aleve®) and ibuprofen (Advil®).
Can Z-pak cause rapid heartbeat?
Some can disrupt the heart’s electrical activity and lead to a (sometimes lethal) rapid heartbeat. Azithromycin (Z-pak) is one popular antibiotic that multiple studies have linked to an increase in arrhythmia-related cardiovascular deaths. Levofloxacin has shown a similar risk.
Can you take anticoagulants and antiplatelet drugs at the same time?
In the WOEST trial, which studied angioplasty patients, researchers compared those who took anticoagulants and antiplatelet drugs with aspirin and those who took them without aspirin.
How does levofloxacin work?
How it works. Levaquin is a brand (trade) name for levofloxacin. Levaquin (levofloxacin) works by inhibiting two bacterial enzymes, topoisomerase IV and DNA gyrase, both of which are vital for the manufacture and repair of bacterial DNA and other DNA processes. Levaquin kills bacteria.
How old do you have to be to take Levaquin?
Should only be used by adults (at least 18 years old). The only indicated for pediatric patients aged 6 months and older is the prevention of inhalational anthrax and for plague. Levaquin has caused arthropathy and osteochondrosis in juvenile animal studies.
How does Levaquin work?
Levaquin is a brand (trade) name for levofloxacin. Levaquin (levofloxacin) works by inhibiting two bacterial enzymes, topoisomerase IV and DNA gyrase, both of which are vital for the manufacture and repair of bacterial DNA and other DNA processes. Levaquin kills bacteria.
What is Levaquin used for?
2. Upsides. Levaquin may be used to treat infections of the skin, sinuses, kidneys, bladder, and prostate caused by susceptible bacteria. However, it is usually only used to treat urinary tract infections, chronic bronchitis, or sinusitis when other alternative treatment options have failed or cannot be used.
Can Levaquin be used for urinary tract infections?
However, it is usually only used to treat urinary tract infections , chronic bronchitis, or sinusitis when other alternative treatment options have failed or cannot be used.
Is Levaquin a generic?
Levaquin is available as a generic under the name levofloxacin. 3. Downsides. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: A headache, insomnia, nausea, diarrhea, constipation, and abdominal pain.
Does Levaquin cause nerve pain?
Tendonitis and tendon rupture, peripheral neuropathy (nerve pain in fingers and toes), and central nervous system effects (side effects that affect the brain including psychosis, convulsions, hallucinations) have been associated with Levaquin and other fluoroquinolones.
How to keep levofloxacin in your blood?
Drinking extra water will help prevent some unwanted effects of levofloxacin. This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times, day and night.
How to take levofloxacin?
Measure your dose with a marked measuring spoon, oral syringe, or medicine cup. You may take levofloxacin tablets with meals or on an empty stomach. This medicine is best taken with a full glass (8 ounces) of water. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor.
Can you take levofloxacin with water?
You may take levofloxacin tablets with meals or on an empty stomach. This medicine is best taken with a full glass (8 ounces) of water. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. Drinking extra water will help prevent some unwanted effects of levofloxacin.
Can antibiotics cause heart problems?
FDA warns some antibiotics can cause fatal heart damage. Drugs commonly used to treat upper respiratory infection, urinary tract infections should not be prescribed to patients already at risk.
Can you prescribe fluoroquinolones to patients with high blood pressure?
Prescribe fluoroquinolones to these patients only when no other treatment options are available,” the FDA said. Patients should call 911 or get to an emergency room if they feel symptoms of an aortic dissection, which include sudden, severe, and constant pain in the stomach, chest or back, the FDA said. People who have high blood pressure, who know ...
Can fluoroquinolone cause aortic dissection?
Fluoroquinolone antibiotics might raise the risk of an aortic dissection, and people who are already at risk should be cautious about taking those antibiotics, the FDA said. “A U.S. Food and Drug Administration (FDA) review found that fluoroquinolone antibiotics can increase the occurrence of rare but serious events of ruptures or tears in ...
Can fluoroquinolones cause bleeding?
These tears, called aortic dissections, or ruptures of an aortic aneurysm can lead to dangerous bleeding or even death,” the FDA said in a statement. “Fluoroquinolones should not be used in patients at increased risk unless there are no other treatment options available.
Why should fluoroquinolone be used only when absolutely necessary?
The agency has already warned that the powerful drugs should only be used when absolutely necessary because they can cause other side effects involving tendons, muscles, joints, nerves and the central nervous system.
Can antibiotics cause a fatal artery injury?
Dec. 20, 2018, 2:12 PM PST. By Maggie Fox. Certain antibiotics can cause painful and sometimes fatal damage to the body’s main artery, the Food and Drug Administration said Thursday.
Can antibiotics affect your heart?
Getty Images. A common type of antibiotics called fluoroquinolones may increase the risk of certain cardiac ailments . A new study found that people who took this type of drug had double the risk of certain cardiac issues.
Can antibiotics cause heart valve problems?
Recent research finds that a commonly used class of antibiotics can cause a potentially serious heart valve condition. These drugs, called fluoroquinolones, have also been found to cause other significant health issues, such as nerve damage. Experts emphasized considering the benefits and hazards of this medication before prescribing, ...
Can antibiotics double your chances of heart disease?
Your chances of developing a severe and potentially life-threatening heart condition can double if you take a commonly prescribed class of antibiotics, researchers find. These antibiotics are called fluoroquinolones, and a new study published this month finds people taking them had an increased risk of developing aortic ...
How much more risk of heart valve condition?
2.5 times greater risk of heart valve condition. According to Etminan, this was the first time that recent exposure to fluoroquinolones was associated with an almost 2.5 times increased risk of causing blood to flow back into the heart. The risk was highest within 30 days of use.
How long does it take for a fluoroquinolone to cause heart problems?
The risk was highest within 30 days of use. Even those who had stopped taking the medications within the last 60 days were still 1.5 times more likely to develop heart valve trouble when compared to the amoxicillin users. According to the National Library of Medicine, fluoroquinolone antibiotics include:
Can fluoroquinolone cause numbness?
They’re typically felt in the arms and legs and can include numbness, tingling, burning, or a shooting pain. But experts advise that this risk only occurs with fluoroquinolones taken by mouth or injection. Topical formulations, which are applied to the ears or eyes, have not been found to increase this risk.
Can antibiotics cause nerve damage?
Trusted Source. that this class of antibiotic could cause a sudden and potentially permanent form of nerve damage called peripheral neuropathy. Peripheral neuropathy symptoms depend on which nerves are affected. They’re typically felt in the arms and legs and can include numbness, tingling, burning, or a shooting pain.

How It Works
This medication is used to treat a variety of bacterial infections.
May Treat: Enterococcus urinary tract infection · Plague · Skin and skin structure infection · Pneumococcal pneumonia · Klebsiella pneumonia and more
Brand Names: Levaquin · Iquix · Quixin · Levaquin Leva-Pak
Drug Class: Fluoroquinolone Antibiotics · Ophthalmic Antibiotic - Fluoroquinolones
Availability: Prescription Required
Pregnancy: Consult a doctor before using
May Treat: Enterococcus urinary tract infection · Plague · Skin and skin structure infection · Pneumococcal pneumonia · Klebsiella pneumonia and more
Brand Names: Levaquin · Iquix · Quixin · Levaquin Leva-Pak
Drug Class: Fluoroquinolone Antibiotics · Ophthalmic Antibiotic - Fluoroquinolones
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
Driving: May cause drowsiness or dizziness. Use caution
Upsides
Downsides
Bottom Line
Tips
Response and Effectiveness
- Levofloxacin may be used to treat infections of the skin, sinuses, kidneys, bladder, and prostate caused by susceptible bacteria. However, it is usually only used in the treatment of urinary tract...
- Levofloxacin may also be used to treat certain types of lung infections.
- May be given as a preventive measure when people have been exposed to anthrax.
- Levofloxacin may be used to treat infections of the skin, sinuses, kidneys, bladder, and prostate caused by susceptible bacteria. However, it is usually only used in the treatment of urinary tract...
- Levofloxacin may also be used to treat certain types of lung infections.
- May be given as a preventive measure when people have been exposed to anthrax.
- Effective against susceptible strains of a number of different gram-positive and gram-negative bacteria, for example: Staphylococcus aureus (methicillin-susceptible strains only), S. epidermidis (m...
Interactions
- If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: 1. Headache, insomnia, nausea, diarrhea, constipation, and abdominal pain. 2. Tendonitis and tendon rupture, peripheral neuropathy (nerve pain in fingers and toes) and central nervous system effects (side effects tha…
Further Information
- Levofloxacin treats a wide range of bacterial infections; however, it can cause some very severe and potentially irreversible side effects such as tendonitis or tendon rupture and should only be used to treat infections that have not responded to alternative treatment options.