Precautions
It is supplied by Janssen Pharmaceuticals. Parafon Forte DSC is used in the treatment of muscle spasm and belongs to the drug class skeletal muscle relaxants. FDA has not classified the drug for risk during pregnancy. Parafon Forte DSC 500 mg is not a controlled substance under the Controlled Substances Act (CSA).
What is Parafon Forte DSC 500 mg?
Pill with imprint MCNEIL PARAFON FORTE DSC is Green, Elliptical / Oval and has been identified as Parafon Forte DSC 500 mg. It is supplied by Janssen Pharmaceuticals. Parafon Forte DSC is used in the treatment of muscle spasm and belongs to the drug class skeletal muscle relaxants. FDA has not classified the drug for risk during pregnancy.
Is McNeil Parafon Forte DSC 500 mg safe during pregnancy?
Parafon Forte may be used alone or with other medications. Parafon Forte belongs to a class of drugs called Skeletal Muscle Relaxants. What are the possible side effects of Parafon Forte?
What class of drug is Parafon Forte?
Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions. This medicine is used with rest, PT (physical therapy), pain drugs, and other therapies. Rarely, Parafon Forte DSC (chlorzoxazone)...
Can I drink alcohol with Parafon Forte DSC (chlorzoxazone)?
What are some things I need to know or do while I take Parafon Forte DSC?
What are some side effects that I need to call my doctor about right away?
What are some other side effects of Parafon Forte DSC?
What are the symptoms of an allergic reaction?
Does Parafon Forte cause liver problems?
Can you take Parafon Forte DSC on a regular basis?
Can Parafon Forte change urine color?
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About this website
Is chlorzoxazone controlled substance?
Carisoprodol is the only muscle relaxant that is classified as a controlled substance. Chlorzoxazone (Lorzone) has been associated with serious (including fatal) liver damage, although the incidence is rare. Even so, the drug should not be prescribed at all for people with liver disease or hepatitis.
Is Parafon Forte still on the market?
The Parafon Forte DSC brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
What kind of medicine is Parafon Forte?
Parafon Forte is a prescription medicine used to treat the symptoms of Musculoskeletal Pain. Parafon Forte may be used alone or with other medications. Parafon Forte belongs to a class of drugs called Skeletal Muscle Relaxants.
Why was Parafon Forte taken off the market?
The current labeling for Parafon Forte DSC states that "approximately thirty-six patients" have been reported in whom chlorzoxazone was suspected as the cause of liver damage, but that many of these patients had cancer or some other type of liver disease.
Is chlorzoxazone a strong muscle relaxer?
Chlorzoxazone (95-25-0) is a strong oxidizing agent and used as a skeletal muscle relaxant and as an analgesic.
Why was chlorzoxazone discontinued?
SUMMARY: The Food and Drug Administration (FDA) has determined that PARAFLEX (Chlorzoxazone) Tablets, 250 milligrams (mg), was not withdrawn from sale for reasons of safety or effectiveness.
Is chlorzoxazone a benzo?
Although chlorzoxazone is not classified as a benzodiazepine, it may interact with benzodiazepine receptors, thus making flumazenil potentially useful in overdose states.
Is chlorzoxazone a sedative?
Chlorzoxazone is a benzoxazolone derivative with mild sedative and centrally-acting muscle relaxant activities.
How fast does chlorzoxazone work?
Chlorzoxazone has an onset of action within 1 hour and a plasma half-life of 1 to 2 hours. The duration of action is 3 to 4 hours. The drug is available in 250- and 500-mg caplets, and the recommended adult dose is 250 to 750 mg taken 3 or 4 times daily.
What class drug is CHLORZOXAZONE?
Chlorzoxazone is a skeletal muscle relaxant.
Does parafon make you sleepy?
Drowsiness, dizziness, lightheadedness, tiredness, upset stomach, or headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. This medication may rarely cause your urine to turn orange or reddish-purple.
Is Parafon Forte a good muscle relaxant?
This muscle relaxant is the most effective I've tried, with the least drastic side effects. It can make you a little dizzy or woozy and maybe a slight headache, but not bad enough to stop taking them.
What is the generic name for Parafon Forte?
Chlorzoxazone is used to treat muscle spasms/pain. It is usually used along with rest, physical therapy, and other treatment.
What is the brand name for Chlorzoxazone?
Chlorzoxazone and Robaxin (methocarbamol) are skeletal muscle relaxants indicated as adjuncts to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions and injuries. Brand names for include chlorzoxazone include Lorzone and Parafon Forte DSC.
Is Parafon Forte a good muscle relaxer?
This muscle relaxant is the most effective I've tried, with the least drastic side effects. It can make you a little dizzy or woozy and maybe a slight headache, but not bad enough to stop taking them.
What is the difference between Chlorzoxazone and cyclobenzaprine?
Flexeril (cyclobenzaprine) is widely used to treat muscle spasms and is available as a generic, but it shouldn't be used long-term. Parafon Forte DSC (chlorzoxazone) works just as well as other medicines used for muscle pain caused by spasms. Parafon Forte DSC (chlorzoxazone) is available in generic.
Parafon Forte DSC Oral: Uses, Side Effects, Interactions ... - WebMD
Find patient medical information for Parafon Forte DSC oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Parafon Forte Oral: Uses, Side Effects, Interactions, Pictures ... - WebMD
Find patient medical information for Parafon Forte oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Parafon Forte DSC (chlorzoxazone) dose, indications, adverse effects ...
PDR Drug Summaries are concise point-of-care prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice PDR's drug summaries are available free of charge and serve as a great resource for US based MDs, DOs, NPs and PAs in patient practice
Parafon Forte (Chlorzoxazone): Uses, Dosage, Side Effects ... - RxList
INDICATIONS. PARAFON FORTE DSC chlorzoxazone is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions.The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Chlorzoxazone does not directly relax tense skeletal muscles in man.
Parafon Forte (Chlorzoxazone – Acetaminophen) - RxMed
PARAFON FORTE® Johnson & Johnson Merck . Chlorzoxazone – Acetaminophen . Muscle Relaxant – Analgesic . Action And Clinical Pharmacology: Parafon Forte tablets combine the muscle-relaxant effect of chlorzoxazone with acetaminophen, a well-known analgesic. Chlorzoxazone is a centrally acting agent for painful musculoskeletal conditions.
What is Parafon Forte used for?
What is Parafon Forte and how is it used? Parafon Forte is a prescription medicine used to treat the symptoms of Musculoskeletal Pain. Parafon Forte may be used alone or with other medications. Parafon Forte belongs to a class of drugs called Skeletal Muscle Relaxants.
How does chlorzoxazone work?
The clinical result is a reduction of the skeletal muscle spasm with relief of pain and increased mobility of the involved muscles. Blood levels of chlorzoxazone can be detected in people during the first 30 minutes and peak levels may be reached, in the majority of the subjects, in about 1 to 2 hours after oral administration of chlorzoxazone. Chlorzoxazone is rapidly metabolized and is excreted in the urine, primarily in a conjugated form as the glucuronide. Less than one percent of a dose of chlorzoxazone is excreted unchanged in the urine in 24 hours.
How long does it take for chlorzoxazone to peak?
Blood levels of chlorzoxazone can be detected in people during the first 30 minutes and peak levels may be reached, in the majority of the subjects, in about 1 to 2 hours after oral administration of chlorzoxazone.
What are the symptoms of a swollen stomach?
Symptoms. Initially, gastrointestinal disturbances such as nausea, vomiting, or diarrhea together with drowsiness, dizziness, lightheadedness or headache may occur . Early in the course there may be malaise or sluggishness followed by marked loss of muscle tone, making voluntary movement impossible.
What is the treatment for emesis?
Gastric lavage or induction of emesis should be carried out, followed by administration of activated charcoal. Thereafter, treatment is entirely supportive. If respirations are depressed, oxygen and artificial respiration should be employed and a patent airway assured by use of an oropharyngeal airway or endotracheal tube. Hypotension may be counteracted by use of dextran, plasma, concentrated albumin or a vasopressor agent such as norepinephrine. Cholinergic drugs or analeptic drugs are of no value and should not be used.
Does chlorzoxazone cause gastrointestinal bleeding?
Chlorzoxazone containing products are usually well tolerated. It is possible in rare instances that chlorzoxazone may have been associated with gastrointestinal bleeding. Drowsiness, dizziness, lightheadedness , malaise, or overstimulation may be noted by an occasional patient. Rarely, allergic-type skin rashes, petechiae, or ecchymoses may develop during treatment. Angioneurotic edema or anaphylactic reactions are extremely rare. There is no evidence that the drug will cause renal damage. Rarely, a patient may note discoloration of the urine resulting from a phenolic metabolite of chlorzoxazone. This finding is of no known clinical significance.
Is PARAFON FORTE DSC a sedative?
PARAFON FORTE DSC chlorzoxazone is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Chlorzoxazone does not directly relax tense skeletal muscles in man.
When should chlorzoxazone be discontinued?
Chlorzoxazone use should also be discontinued if a patient develops abnormal liver enzymes (e.g. AST, ALT, alkaline phosphatase and bilirubin).
How does chlorzoxazone work?
The clinical result is a reduction of the skeletal muscle spasm with relief of pain and increased mobility of the involved muscles. Blood levels of chlorzoxazone can be detected in people during the first 30 minutes and peak levels may be reached, in the majority of the subjects, in about 1 to 2 hours after oral administration of chlorzoxazone. Chlorzoxazone is rapidly metabolized and is excreted in the urine, primarily in a conjugated form as the glucuronide. Less than one percent of a dose of chlorzoxazone is excreted unchanged in the urine in 24 hours.
Is Parafon Forte DSC chlorzoxazone contraindicated?
Parafon Forte DSC chlorzoxazone is contraindicated in patients with known intolerance to the drug.
Does Parafon Forte relax skeletal muscles?
Parafon Forte DSC chlorzoxazone is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Chlorzoxazone does not directly relax tense skeletal muscles in man.
Is Parafon Forte discontinued?
The Parafon Forte DSC brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Is chlorzoxazone safe for gastrointestinal bleeding?
Chlorzoxazone containing products are usually well tolerated. It is possible in rare instances that chlorzoxazone may have been associated with gastrointestinal bleeding. Drowsiness, dizziness, lightheadedness, malaise, or overstimulation may be noted by an occasional patient. Rarely, allergic-type skin rashes, petechiae, or ecchymoses may develop during treatment. Angioneurotic edema or anaphylactic reactions are extremely rare. There is no evidence that the drug will cause renal damage. Rarely, a patient may note discoloration of the urine resulting from a phenolic metabolite of chlorzoxazone. This finding is of no known clinical significance.
What is Parafon Forte used for?
Chlorzoxazone is used to relax certain muscles in your body and relieve the discomfort caused by acute (short-term), painful muscle or bone conditions. However, this medicine does not take the place of rest, exercise, physical therapy, or other treatments that your doctor may recommend for your medical condition.
What are some examples of CNS depressants?
Some examples of CNS depressants are antihistamines or medicine for hay fever, allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; or anesthetics, including some dental anesthetics.
Why is it important to check your progress with your doctor?
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.
Is Parafon Forte discontinued?
The Parafon Forte DSC brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Can you take Zolpidem and Triazolam together?
Triazolam. Zolpidem. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Does Parafon Forte have side effects?
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Rare. Bloody or black, tarry stools.
Is chlorzoxazone safe for children?
No information is available on the relationship of age to the effects of chlorzoxazone in the pediatric population. Safety and efficacy have not been established.
What are some things I need to know or do while I take Parafon Forte DSC?
Tell all of your health care providers that you take Parafon Forte DSC (chlorzoxazone). This includes your doctors, nurses, pharmacists, and dentists.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
What are some other side effects of Parafon Forte DSC?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
What are the symptoms of an allergic reaction?
Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
Does Parafon Forte cause liver problems?
Liver problems have rarely happened with Parafon Forte DSC (chlorzoxazone). Sometimes, this has been deadly. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
Can you take Parafon Forte DSC on a regular basis?
If you take Parafon Forte DSC (chlorzoxazone) on a regular basis, take a missed dose as soon as you think about it.
Can Parafon Forte change urine color?
Rarely, Parafon Forte DSC (chlorzoxazone) may change the color of the urine. This is normal and not a cause for concern. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
