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what causes pigment loss in skin

by Maudie Walker Published 3 years ago Updated 2 years ago
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Skin layers and melanin
Vitiligo occurs when pigment-producing cells (melanocytes) die or stop producing melanin — the pigment that gives your skin, hair and eyes color. The involved patches of skin become lighter or white. It's unclear exactly what causes these pigment cells to fail or die.
May 4, 2022

Why is my skin losing pigment?

What causes vitiligo?

  • Autoimmune conditions. Non-segmental vitiligo (the most common type) is thought to be an autoimmune condition. ...
  • Risk factors
  • Neurochemicals. Segmental vitiligo (the less common type) is thought to be caused by chemicals released from the nerve endings in your skin.
  • Triggers. ...

What causes decreased skin pigmentation?

Pigmentation alteration (change) as a result of skin damage (post-inflammatory hyper- or hyperpigmentation). If you have had a skin infection, blisters, burns, or other trauma to your skin, you may have a decrease or increase of pigmentation in the affected area.

Does vitiligo go away?

The simple one-word answer to the most important question about vitiligo is: Yes! Getting vitiligo to actually go away for you may not be so simple. Absolutely, vitiligo goes away. But how? That’s the rub. How does vitiligo go away for you?

Which pigment is responsible for darkening of human skin?

Types of hyperpigmentation

  • Melasma. Melasma is believed to be caused by hormonal changes and may develop during pregnancy. ...
  • Sunspots. Also called liver spots or solar lentigines, sunspots are common. They’re related to excess sun exposure over time. ...
  • Post-inflammatory hyperpigmentation. This is a result of injury or inflammation to the skin. A common cause of this type is acne.

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How do you get skin pigment back?

Your skin's pigmentation, or color, is based on the production of a substance called melanin. If your skin cells don't produce enough melanin, the skin can lighten....Treatment options may include:dermabrasion.chemical peels.laser resurfacing or therapy.lightening gels, such as hydroquinone (Blanche)

How do you fix skin pigment loss?

There is no cure. Treatment may include covering smaller patches with long-lasting dyes, light-sensitive medicines, UV light therapy, corticosteroid creams, surgery, and removing the remaining pigment from the skin (depigmentation).

Where does vitiligo usually start?

Vitiligo typically begins on the hands, forearms, feet, and face but can develop on any part of the body, including the mucous membranes (moist lining of the mouth, nose, genital, and rectal areas), the eyes, and inner ears.

What triggers vitiligo?

Vitiligo is a skin condition that changes pigmentation. Vitiligo triggers include autoimmune disease, neurogenic factors, genetics, sunburn, stress and chemical exposure.

How long does it take for pigment to come back?

It is difficult to say how long it will take the color to return to normal, but typically I would say 2-3 months. Make sure you are going to a medically-supervised clinic for your IPL or laser treatments to minimize this risk of discoloration and more importantly burns.

What autoimmune disease causes skin discoloration?

Vitiligo is an autoimmune disease that causes your skin to lose color, often resulting in white patches on your skin that cover both sides of your body.

What can be mistaken for vitiligo?

Sometimes, vitiligo is mistaken for albinism, a group of inherited skin disorders that result in little or no pigment in a person's skin, eyes, and hair.

What are the early stages of vitiligo?

Vitiligo often starts as a pale patch of skin that gradually turns completely white. The centre of a patch may be white, with paler skin around it. If there are blood vessels under the skin, the patch may be slightly pink, rather than white. The edges of the patch may be smooth or irregular.

Can you stop vitiligo from spreading?

There is currently no known way to prevent or cure vitiligo. However, you can sometimes prevent your symptoms from getting worse or spreading. Some vitiligo prevention strategies—such as diet and taking vitamins—are focused on boosting the immune system.

Does stress cause vitiligo to spread?

People with vitiligo have reported that emotional stress causes more patches to develop.

Who are more prone to vitiligo?

However, for many people with vitiligo, the white patches begin to appear before age 20, and can start in early childhood. Vitiligo seems to be more common in people who have a family history of the disorder or who have certain autoimmune diseases, including: Addison's disease. Pernicious anemia.

Can you suddenly develop vitiligo?

People can develop vitiligo at any age, but approximately one-half of cases are diagnosed either in childhood or before someone turns 20. The first signs of vitiligo are white patches on the skin, which can develop anywhere on the body, including on the face, arms, hands, genitals, and buttocks.

What causes pigment loss?

It's sometimes limited to small patches of skin but may be more generalized. Understanding the nature of the pigment loss is key to determining the most appropriate next steps. Common causes of pigment loss include skin conditions like vitiligo, inflammation, wound healing with scarring, ...

What are the most common skin disorders associated with pigment loss?

Vitiligo and Pityriasis Alba. Two of the most common skin disorders associated with pigment loss have causes that are not completely understood 5. Vitiligo typically occurs during the first 3 decades of life and is characterized by smooth, white patches of skin. Pityriasis alba, which is most often observed in young children, ...

What chemicals can cause skin color changes?

Exposure to certain chemicals can cause skin color changes. For example, an antioxidant used in rubber manufacturing -- monobenzyl ether of hydroquinone -- was one of the first chemicals noted to be associated with occupation-related pigment loss.

What is the name of the rash on the face?

Pityriasis alba, which is most often observed in young children, may first appear as a red scaly rash, typically on the face and arms. The rash often resolves spontaneously but leaves dry, white patches as it heals. These patches eventually disappear, causing no permanent pigment loss. Two of the most common skin disorders associated ...

Why does Tinea versicolor itch?

Tinea versicolor, due to a fungus, is characterized by dry, scaly patches that may be lighter or darker than the surrounding skin and may itch. It may appear anywhere on the body and may be just a few spots or widespread. Pigment loss can also occur after certain viral infections like chickenpox. Several types of infection can cause pigment loss 7. ...

What is the name of the condition where you get white hair on your forehead?

Piebaldism, another genetic condition, usually results in a patch of white hair near the forehead, or a white forelock 8. There may also be areas of unpigmented skin on the forehead, trunk, arms and legs. Nevus depigmentosus is something akin to a freckle or mole that has no color.

Is albinism a genetic condition?

It's considered a congenital condition that a person is born with, but it has no known pattern of inheritance. Albinism is a group of genetic conditions associated with reduced pigment affecting the eyes and other areas, such as the skin and hair 7.

What is skin pigment disorder?

What are skin pigment disorders? Skin color is determined by a pigment (melanin) made by specialized cells in the skin (melanocytes). The amount and type of melanin determines a person's skin color.

How does sun exposure affect melanin?

Levels of melanin depend on race and amount of sunlight exposure. Sun exposure increases melanin production to protect the skin against harmful UV (ultraviolet) rays. In addition, hormonal changes can affect melanin production.

Why does my skin turn white after a burn?

Makeup can usually cover the blemish. This causes smooth, white patches on the skin. It is caused by the loss of pigment-producing cells in the skin ( melanocytes).

How to treat melasma?

Treatment. Sunscreens and avoiding sun exposure can prevent melasma from becoming worse. Other treatment may include prescription creams containing hydroquinone and tretinoin to lighten the patches. Chemical peels and laser treatment can also be used. Pigment loss after skin damage. Characteristics.

What are the characteristics of melasma?

Melasma. Characteristics. Dark brown to gray-brown, symmetric patches of pigment on the face. During pregnancy, this is called the mask of pregnancy.

What to do about white patches on face?

There is no cure. Treatment may include covering smaller patches with long-lasting dyes, light-sensitive medicines, UV light therapy , corticosteroid creams, surgery, and removing the remaining pigment from the skin (depigmentation).

Does albinism cause red eyes?

Their eyes may seem red in different lighting conditions. Many also have vision problems. There is no cure for albinism.

Main causes of pigment loss

Pityriasis alba: This is a skin pigmentation disorder that is often seen in children but it can appear in adults as well. A characteristic rash is present at the level of the face and arms, with the skin being red and scaly. As the rash begins to heal, white patches of dry skin appear instead.

How to deal with skin pigment loss

When you suffer from skin pigment loss, whether it is temporary or permanent, it is only normal that you ask yourself: how to have beautiful skin? Well, there are a number of solutions that you can resort to, in order to improve the general appearance of the skin.

Conclusion

When you suffer from pigment loss, it is important not to despair. You need to seek out a correct diagnosis and, based on the respective diagnosis, follow the most recommended treatment courses. At the same time, you need to stay away from the sun, protecting your skin with sunscreen that has high SPF (when you do have to go out).

Why do my eyes discolor?

The discoloration is caused by increased amounts of the pigment (melanin) and the cells that produce this pigment (melanocytes) in and around the eyes. Patients with this type of birthmark are at a higher risk of developing a melanoma cancer of their eye or central nervous system.

Why is my port wine stain purple?

Port wine stains are caused by abnormal development of blood vessels (capillaries). Over time, the port wine stain may become raised and thickened.

What are the birthmarks that are 0.5 cm in diameter?

However, 6 or more of these spots that are greater than 0.5 cm in diameter can be associated with the genetic disorder neurofibromatosis. These birthmarks may be treated with a laser for cosmetic purposes. Nevi (moles) These spots may be flesh-colored to light-to-dark brown. They may be flat or raised.

Why do we treat hemangioma?

Reasons to treat a hemangioma include problems with functions (such as sight, eating, hearing, or defecation), ulceration, bleeding, or pain. If necessary, hemangiomas can be treated in different ways, each of which carries its own risks. Corticosteroid medication can be injected or taken orally (by mouth).

How long does it take for a skin rash to fade?

This type of alteration is usually not permanent, but may take up to several months to fade or get better. Cosmetics can be used to cover the area.

How to treat port wine stains?

Physicians have tried many ways to treat port wine stains, including radiation, tattooing, freezing, dermabrasion, or sclerotherapy. Laser therapy is currently the treatment of choice, as it is the only method that destroys capillaries in the skin without causing damage to the rest of the skin.

When do birthmarks appear?

Birthmarks. As might be expected, these abnormal skin colorations will appear at birth or just a few weeks after birth. While most birthmarks are non-cancerous, certain birthmarks, described below, can pose health risks.

Why do pigments die?

It may be related to: A disorder of the immune system (autoimmune condition) Family history (heredity) A trigger event, such as stress, severe sunburn or skin trauma, such as contact with a chemical.

What happens when pigments die?

Vitiligo occurs when pigment-producing cells (melanocytes) die or stop producing melanin — the pigment that gives your skin, hair and eyes color. The involved patches of skin become lighter or white. It's unclear exactly what causes these pigment cells to fail or die. It may be related to:

How does vitiligo affect the body?

Normally, the color of hair and skin is determined by melanin. Vitiligo occurs when cells that produce melanin die or stop functioning. Vitiligo affects people of all skin types, but it may be more noticeable in people with darker skin.

What is vitiligo on the face?

The loss of color resulting from vitiligo is sometimes symmetrical. Open pop-up dialog box. Close. Vitiligo. Vitiligo. Vitiligo is a condition in which the skin loses its pigment cells (melanocytes). This can result in discolored patches in different areas of the body, including the skin, ...

Why do my eyes turn white?

It's produced in cells called melanocytes. Vitiligo occurs when pigment-producing cells (melanocytes) die or stop producing melanin — the pigment that gives your skin, hair and eyes color. The involved patches of skin become lighter or white.

What are the risks of vitiligo?

People with vitiligo may be at increased risk of: 1 Social or psychological distress 2 Sunburn 3 Eye problems 4 Hearing loss

What is the most common type of vitiligo?

Nearly all skin surfaces. With this type, called universal vitiligo, the discoloration affects nearly all skin surfaces. Many parts of your body. With this most common type, called generalized vitiligo, the discolored patches often progress similarly on corresponding body parts (symmetrically).

What causes pigmentation on the skin?

Your skin tone is the result of a complex process during which special cells inside the outer layer of your skin called melanocytes produce melanin. Inside these special skin cells are organelles (or mini-organs of the cell) called melanosomes. Variations in the color of your skin depend on the amount, size, ...

How does skin pigmentation work?

Your skin pigmentation is determined by the balance of these types of melanin in your skin. This can shift depending on your hormones, interactions with other cells in your body, the impact of certain genes, and more.

What are the two types of melanin?

There are two key types of melanin: eumelanin and pheomelanin: 1 Eumelanin is brown and black in color. It protects your skin by limiting the amount of harmful ultraviolet (UV) rays that can break through and picking up reactive oxygen radicals which—if left alone—could damage your cells and DNA and potentially lead to chronic health conditions like cancer. 2 Pheomelanin, on the other hand, is yellow and red in color. Unlike eumelanin, pheomelanin provides very little protection from UV rays and can actually support the production of reactive oxygen radicals and the damage they cause. 1 

How many genes affect skin pigmentation?

Amazingly, over 125 genes are known to affect skin pigmentation. Along with hormones, genes are responsible for regulating the melanin production process. They can adjust how much eumelanin or pheomelanin your skin cells produce and how well they survive and function, causing shifts in skin color over time. 2 

Why does my skin turn white?

Depigmentation occurs when your skin completely loses pigment and turns white. One common cause of depigmentation is vitiligo, an autoimmune condition that causes smooth, white patches to appear on the skin.

Why is my skin darker?

Your skin could become darker or lighter due to changes in your body’s production of melanin. A variety of factors could cause this, from the genes you’re born with to skin damage ...

Why does my skin change color?

Pigment disorders, injuries, and other changes in your body can cause your skin to lighten, darker, or change in color. You might notice changes in your skin tone in multiple areas on the surface of your skin or only in certain patches of skin.

Why does my skin lighten?

If your skin cells don’t produce enough melanin, the skin can lighten. These effects can occur in spots or may cover your entire body. Genetic and severe environmental conditions can cause melanin disruption. It’s important to identify the root cause before undergoing treatment.

What is the cause of a lighter skin color?

Vitiligo. Like albinism, vitiligo is characterized by lighter skin. However, this occurs in patches that cover your skin, rather than a widespread lack of color. The exact cause of vitiligo is unknown. People who have this condition can develop lighter patches of skin anywhere on the body.

What is hypopigmentation skin?

What is hypopigmentation? Hypopigmentation refers to patches of skin that are lighter than your overall skin tone. Your skin’s pigmentation, or color, is based on the production of a substance called melanin. If your skin cells don’t produce enough melanin, the skin can lighten.

Why does Tinea versicolor have scaly spots?

Tinea (pityriasis) versicolor stems from a fungal infection that occurs from overactive yeast on the skin. Though it doesn’t lead to complications, the resulting scaly spots can become a nuisance.

Why is melanin so light?

Problems with melanin production are linked to a variety of causes. Some are genetic conditions that may result in lighter skin throughout the body. Others are related to previous injuries, such as burns. It’s also possible for hypopigmentation from an injury to develop into an associated condition.

Why do my skin patches turn white?

This includes: Atopic dermatitis. Also known as eczema, this skin condition causes red patches that are extremely itchy. As the skin heals, the patches may turn white. Contact dermatitis. Touching chemicals may lead to this type of eczema and may cause lightened skin. Healed blisters.

What is the term for white spots on the skin?

Pityriasis alba. Pityriasis alba refers to leftover white spots from previous cases of red, scaly skin patches. This condition tends to heal on its own over time. There’s no definitive cause for pityriasis alba, though it’s thought to be related to eczema. Children with this condition may outgrow it in adulthood.

How to get rid of vitiligo on skin?

There are some things you can do at home to help your skin look better: Cover affected skin with makeup or tanning products. Use sunscreen (at least SPF 30) when you’re outside, and reapply it every 2 hours. Stay away from tanning beds. Don't get tattoos. The damage they do to your skin can cause more vitiligo.

What is vitiligo on the body?

What Is Vitiligo? Vitiligo is a condition in which white patches develop on the skin. Any location on the body can be affected, and most people with vitiligo have white patches on many areas.

What is the procedure to even out the tone of your skin?

If other treatments haven't worked for you, your doctor may recommend surgery. The goal of these procedures is to even out the tone of your skin. Skin grafting is where a surgeon transfers healthy portions of your skin to the discolored areas. Your doctor might suggest this if you have small patches of vitiligo.

How many types of vitiligo are there?

Vitiligo Types. There are five types of vitiligo. Which type you have depends on where you have it. Generalized is the most common type. This is when discolored patches show up all over your body. Segmental is when your vitiligo is confined to one area of your body, like your face or your hands.

What is the best treatment for vitiligo?

If your vitiligo is progressing quickly, your doctor might suggest a corticosteroid pill or injection. In rare cases, they may suggest an ointment called a calcineurin inhibitor ointment.

How long does it take for vitiligo to lighten?

A substance goes on the unaffected areas of your skin once or twice a day for about 9 months. Gradually, that skin will permanently lighten so that it matches the rest of your skin.

How to diagnose vitiligo?

Your doctor can usually make a diagnosis of vitiligo by looking at your skin during a physical exam. You might also have other tests, including blood tests and: Skin biopsy, where a sample of your skin is sent to a laboratory for further examination. A Wood's lamp test, where a doctor looks at your skin under UV light.

What causes depigmentation of the skin?

Depigmentation of the skin can be caused by a number of local and systemic conditions. The pigment loss can be partial (such as after injury to the skin) or complete (such as from vitiligo ). It can be temporary (such as from tinea versicolor) or permanent (such as from albinism).

Why does my skin turn white?

Vitiligo is a condition in which the skin turns white due to the loss of pigment from the melanocytes, cells that produce the pigment melanin that gives the skin color.

What is the cause of Tinea Versicolor?

Recognized by light or reddish brown spots, and areas lighter than the surrounding skin. Tinea versicolor is caused by yeast actually found in our skin.

What is the human body's skin?

The Skin (Human Anatomy): Picture, Definition, Function and Skin Conditions. The skin is the largest organ in the body that covers the entire external surface. It protects the internal organs from germs and thus helps prevent infections. The skin is made up of three main layers.

How many layers of skin are there?

The 7 Most Important Layers of Your Skin. The skin is the largest organ in the body and it covers the body's entire external surface. It is made up of seven layers. The first five layers form the epidermis, which is the outermost, thick layer of the skin.

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1.6 Causes of a Loss of Skin Pigmentation - Dermstore

Url:https://www.dermstore.com/blog/loss-of-skin-pigmentation/

5 hours ago 4 rows · Sometimes, after an ulcer, blister, burn, or infection, the skin does not replace some of the ...

2.Skin Disorders That Cause Pigment Loss | Healthfully

Url:https://healthfully.com/skin-disorders-that-cause-pigment-loss-3217594.html

32 hours ago Medication: The loss of pigment at the level of the skin can occur as a side-effect of various medication. Both corticosteroids and retinoids can cause temporary or permanent loss of pigment, depending on how long they are used. It is also worth mentioning that, once this loss of pigment occurs, the skin becomes more sensitive to the sun.

3.Skin Pigment Disorders | Johns Hopkins Medicine

Url:https://www.hopkinsmedicine.org/health/conditions-and-diseases/skin-pigment-disorders

30 hours ago Vitiligo is a condition where the body’s immune system attacks pigment cells (melanocytes), causing pigment loss. Other immune system diseases associated with vitiligo include diabetes, pernicious anemia, thyroid disease, and Addison’s disease.

4.Know the reason for pigmentation loss in your skin

Url:https://www.infinitehealthhub.com/know-reason-pigmentation-loss-skin/

35 hours ago  · Vitiligo is a condition in which the skin loses its pigment cells (melanocytes). This can result in discolored patches in different areas of the body, including the skin, hair and mucous membranes. Vitiligo (vit-ih-LIE-go) is a disease that causes loss of skin color in patches. The discolored areas usually get bigger with time.

5.Skin Discoloration & Pigmentation Disorders: Causes

Url:https://my.clevelandclinic.org/health/articles/11014-pigmentation-abnormal-pigmentation

34 hours ago  · Skin Pigment Discoloration Hyperpigmentation. Hyperpigmentation causes skin to become darker or different in color due to an abnormally high amount... Hypopigmentation. Skin with hypopigmentation is lighter in color due to an abnormally low amount of melanin. Depigmentation. Depigmentation occurs ...

6.Vitiligo - Symptoms and causes - Mayo Clinic

Url:https://www.mayoclinic.org/diseases-conditions/vitiligo/symptoms-causes/syc-20355912

26 hours ago  · As your skin heals, lighter pigments may appear in areas affected by the infection. Psoriasis. This autoimmune disorder causes your skin to produce new cells at an accelerated rate. Resulting ...

7.Skin Pigmentation: Genetics, Discoloration, and Treatment

Url:https://www.verywellhealth.com/skin-pigmentation-5088368

32 hours ago  · Vitiligo Causes and Risk Factors The skin doesn't have its characteristic color because it has lost its melanin . For some reason, the pigment-forming cells known as melanocytes have been destroyed.

8.Hypopigmentation: Causes, Risk Factors, Treatments, More

Url:https://www.healthline.com/health/skin-disorders/hypopigmentation

10 hours ago  · Other causes of depigmentation of skin Albinism (Inherited Lack of Skin Pigment) Dermatitis (Inflammation of the Skin) Infection (Commonly Fungus Called Tinea Alba or Pityriasis Versicolor) Steroid ( Corticosteroids, Either Topical or Injected) Trauma Injury to Skin

9.Vitiligo: Symptoms, Causes, Treatments - WebMD

Url:https://www.webmd.com/skin-problems-and-treatments/guide/vitiligo-common-cause-loss-skin-pigment

19 hours ago

10.Depigmentation of Skin: Symptoms, Signs, Causes

Url:https://www.medicinenet.com/depigmentation_of_skin/symptoms.htm

14 hours ago

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