What drugs should be avoided with a sulfa allergy?
Apr 24, 2020 · What diuretic is safe with sulfa allergy? EVIDENCE-BASED ANSWER Diuretics that do not contain a sulfonamide group (eg, amiloride hydrochloride , eplerenone , ethacrynic acid , spironolactone , and triamterene ) are safe for patients with an allergy to sulfa.
Which medications to avoid in patients with sulfa allergy?
Which diuretics are safe and effective for patients with a sulfa allergy? evidence-based answer Diuretics that do not contain a sulfonamide group (eg, amiloride hydrochloride, eplerenone, ethacrynic acid, spironolactone, and triamterene) are safe for patients with an allergy to sulfa. The evidence is contradictory
Is Lasix contraindicated for sulfa allergy?
Diuretics that do not contain a sulfonamide group (eg, amiloride hydrochloride, eplerenone, ethacrynic acid, spironolactone, and triamterene) are safe for patients with an allergy to sulfa. Click to see full answer Herein, can you take hydrochlorothiazide if you are allergic to sulfa drugs?
Is it OK to take Celebrex with a sulfa allergy?
EVIDENCE-BASED ANSWER. Diuretics that do not contain a sulfonamide group (eg, amiloride hydrochloride, eplerenone, ethacrynic acid, spironolactone, and triamterene) are safe for patients with an allergy to sulfa. The evidence is contradictory as to whether a history of allergy to sulfonamide antibiotics increases the risk of subsequent allergic reactions to commonly used …
Which diuretic is the best choice for a patient with a sulfa allergy?
Which diuretic do you recommend for a hypertensive patient allergic to sulfonamides? Spironolactone would be a first choice. Another alternative is the loop diuretic with the least cross-reactivity to the sulfonamides, ethacrynic acid.Mar 21, 2008
Can you take furosemide with sulfa allergy?
For most patients with sulfa allergy who have no history of life-threatening reactions and are not allergic to more than one class of sulfonamides, however, available evidence suggests that furosemide can be used safely in an emergency.
Can I take hydrochlorothiazide if I have a sulfa allergy?
Yep, these are safe if you have a sulfa allergy. Thiazide diuretics like chlorthalidone and hydrochlorothiazide (HCTZ) are used to treat high blood pressure and are fine to take even if you've been told you have a sulfa allergy to Bactrim.Jan 16, 2020
Is there sulfa in hydrochlorothiazide?
Hydrochlorothiazide (HCTZ) is a sulfonamide-containing drug with commonly reported adverse effects that include electrolyte abnormalities, orthostatic hypotension, hyperglycemia, and photosensitivity.
What drugs should be avoided with sulfa allergy?
Drugs to Avoid With Sulfa AllergiesSulfamethoxazole / trimethoprim (Bactrim, Sulfatrim), a sulfa combination drug that can be taken in liquid or pill form for many types of infections.Sulfacetamide (BLEPH-10), drops for eye infections.Sulfadiazine silver (Silvadene), a cream to prevent and treat burn infections.More items...•Aug 5, 2020
Is there sulfa in chlorthalidone?
The pharmacist reports that the drug interaction system is flagging the chlorthalidone as a problem due to ED's allergy to SMX since chlorthalidone also contains a sulfa moiety.
Are hydrochlorothiazide and chlorthalidone the same?
Chlorthalidone produces slightly greater reductions in blood pressure compared with hydrochlorothiazide (HCTZ), but it is associated with greater declines in serum potassium levels.Dec 1, 2015
Is there sulfa in AZO?
BRAND NAME(S): Azo-Gantanol. Please Note: This Drug is no longer available in the United States. USES: This medication contains sulfamethoxazole, a sulfa anti-infective and phenazopyridine, a pain reliever.
What is a thiazide diuretic drug?
Thiazide diuretics are a type of diuretic (a drug that increases urine flow). They act directly on the kidneys and promote diuresis (urine flow) by inhibiting the sodium/chloride cotransporter located in the distal convoluted tubule of a nephron (the functional unit of a kidney).
Is a sulfa allergy the same as a sulfur allergy?
Also, sulfa is different from sulfates and sulfur. Both sulfa medications and sulfite can cause allergic reactions, but these two conditions are not related. A person who has a sulfa allergy will not necessarily have a sulfite allergy, so there is no cross-reactivity.
Can you take lisinopril with sulfa allergy?
You should not use this medicine if you have ever had angioedema, if you are unable to urinate, or if you are allergic to sulfa drugs or to any ACE inhibitor. Do not take hydrochlorothiazide and lisinopril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).
Is Zpack a sulfa drug?
Zithromax and Bactrim belong to different antibiotic drug classes. Zithromax is a macrolide antibiotic and Bactrim is a combination of a sulfonamide antibiotic (a “sulfa” drug) and a folic acid inhibitor.
What are the two classes of sulfonamides?
What we do know is that there are 2 classes of sulfonamides—those with an aromatic amine (the antimicrobial sulfonamides) and those without (eg, the diuretics acetazolamide, furosemide, hydrochlorothiazide, and indapamide). Hypersensitivity reactions occur when the aromatic amine group is oxidized into hydroxylamine metabolites by the liver. Sulfonamides that do not contain this aromatic amine group undergo different metabolic pathways, suggesting that allergic reactions that do occur in this group are not due to cross-reactivity in sulfa-allergic patients. But that point is far from settled by the research.
Is diuretic an older drug?
Given that diuretics are older agents and off- patent, with no company to take up their cause, no one has been willing to challenge outdated package insert warnings. As clinicians who regularly work without a net, we are accustomed to prescribing medications in less than ideal circumstances.
Do sulfonamides have cross reactivity?
Sulfonamides that do not contain this aromatic amine group undergo different metabolic pathways, suggesting that allergic reactions that do occur in this group are not due to cross-reactivity in sulfa-allergic patients. But that point is far from settled by the research.
Is amiloride hydrochloride safe for allergy patients?
EVIDENCE-BASED ANSWER. Diuretics that do not contain a sulfonamide group (eg, amiloride hydrochloride, eplerenone, ethacrynic acid, spironolactone, and triamterene) are safe for patients with an allergy to sulfa. The evidence is contradictory as to whether a history of allergy to sulfonamide antibiotics increases the risk ...
