Precautions
Drugs in the same group of medications as Januvia can also cause joint pain. These other drugs include saxagliptin (Onglyza) and linagliptin (Tradjenta). If you have joint pain after starting Januvia, talk with your doctor right away.
Can other medications be taken with Januvia?
Januvia (sitagliptin) disease interactions. There are 2 disease interactions with Januvia (sitagliptin) which include: pancreatitis. renal dysfunction.
What are the possible side effects of Januvia (sitagliptin)?
Metformin is one of the most commonly prescribed drugs for type 2 diabetes. But it works differently than Januvia. Sometimes, doctors prescribe both metformin and Januvia to manage diabetes. Depending on the prescribed doses of each drug, a doctor might prescribe the combination drug called Janumet.
What is the difference between metformin and Januvia?
But Januvia is meant to be used together with healthy diet and exercise habits. And these measures may lead to weight changes. Hair loss isn’t a reported side effect of Januvia. But it can be an early sign of type 2 diabetes, which Januvia is used to treat. More studies are needed to confirm the effects of blood sugar levels on hair loss.
Does Januvia cause hair loss?
What drugs does sitagliptin interact with?
Most frequently checked interactionsAcetylsalicylic Acid (aspirin)Aspir 81 (aspirin)Aspirin Low Strength (aspirin)Augmentin (amoxicillin / clavulanate)Crestor (rosuvastatin)Fish Oil (omega-3 polyunsaturated fatty acids)Glucophage (metformin)Jardiance (empagliflozin)More items...
What organ does Januvia affect?
Pancreatitis. Pancreatitis is a possible side effect of Januvia. This is a swelling of the pancreas, the organ that creates the hormone insulin.
Does Januvia make you pee more?
Januvia (sitagliptin) does not have an effect on how often you urinate like other medications, such as diuretics (water pill). If you have diabetes, you should always talk to your provider if you notice you need to urinate more often; this can be a sign of high blood sugar.
Why was Januvia taken off the market?
Merck & Co.'s Januvia, a popular diabetes drug, was found to be contaminated with a potential carcinogen. An impurity called a nitrosamine was found in some samples of the drug, which has the chemical name of sitagliptin, the US Food and Drug Administration said Tuesday.
What are the negative effects of Januvia?
The most common side effects of JANUVIA include upper respiratory infection, stuffy or runny nose and sore throat, and headache. JANUVIA may have other side effects, including stomach upset and diarrhea, swelling of the hands or legs, when JANUVIA is used with metformin and rosiglitazone (Avandia ®).
Is there a lawsuit against Januvia?
Those suffering from type 2 diabetes have filed lawsuits against makers of Januvia. In most claims, consumers blame Januvia for dangerous side effects, including pancreatitis and pancreatic cancer.
How much does Januvia lower A1C?
Sitagliptin will decrease postprandial blood glucose and mildly lower fasting blood glucose for a total A1C reduction around 0.8 percent. It is more expensive than other options, such as sulfonylurea hypoglycemics.
Should Januvia be taken in the morning or at night?
You can take Januvia in the morning or at night, but it's best to get into a routine of taking it at the same time each day. Januvia can be taken with or without food. If you miss a dose, take it as soon as you remember.
Can I stop Januvia cold turkey?
Don't stop taking Januvia unless recommended by your doctor. If you stop taking it, your blood sugar levels will go back up.
What is the best medicine to lower A1C?
While results showed liraglutide and insulin were the most (and similarly) effective in keeping A1C levels less than 7%, glimepiride had a smaller effect and sitagliptin showed the lowest effect, resulting in the highest frequency of developing A1C levels persistently greater than 7%.
Is Januvia more effective than metformin?
In a 24-week clinical trial, both Januvia and metformin led to similar improvements in A1c levels in patients with type 2 diabetes. Although both treatments were generally well-tolerated, the incidence of gastrointestinal-related side effects was significantly lower with Januvia (11.6%) compared with metformin (20.7%).
Does Januvia cause weight gain or loss?
Unlike some other Type 2 diabetes medications, Januvia and other gliptins are not associated with weight gain as a side effect. Weight loss, unfortunately, is also not a side effect of Januvia. Instead, Januvia is considered weight-neutral.
Is Januvia safe for kidneys?
Januvia (sitagliptin) can now be used at a lower dose in patients with moderate to severe renal impairment.
How does Januvia work in the body?
Januvia (sitagliptin) may be used to treat type 2 diabetes and is thought to work by increasing insulin release and decreasing glucagon levels by slowing the inactivation of incretin hormones. Incretin hormones are released by the intestine throughout the day and in response to food.
Does Januvia weaken your immune system?
Immune system: Sitagliptin can reduce the number of cells that fight infection in the body (white blood cells). This side effect may be more of a concern for people who already have a weakened immune system.
Who should not take Januvia?
JANUVIA should not be used in patients with type 1 diabetes or with diabetic ketoacidosis (increased ketones in the blood or urine). If you have had pancreatitis (inflammation of the pancreas), it is not known if you have a higher chance of getting it while taking JANUVIA.
How many diseases interact with Januvia?
There are 2 disease interactions with Januvia (sitagliptin):
Does Linagliptin require a dose adjustment?
Patients with moderate to severe renal insufficiency and end stage renal dysfunction will require a dose adjustment. Linagliptin will not require a dose adjustment per manufacturer's information.
What medications interact with Januvia?
Speak to your doctor about how drug interactions should be managed. Common medications that may interact with Januvia include: digoxin. other medications for diabetes, such as insulin, chlorpropamide, glimepiride, glipizide, glyburide, tolazamide, or tolbutamide. Alcohol may affect your blood sugar levels.
What is Januvia brand?
Januvia is a brand (trade) name for sitagliptin.
How long does Januvia take to absorb?
Januvia is rapidly absorbed with peak plasma concentrations occurring one to four hours after a dose. Administration of one dose of Januvia leads to inhibition of DPP-4 activity for 24 hours.
Does Januvia cause heart failure?
Use of Januvia may precipitate heart failure in those at higher risk for heart failure. The dosage of Januvia requires adjusting in moderate and severe renal disease. The dosage of other antidiabetic medications (such as sulfonylureas or insulin) may need adjusting to reduce the risk of hypoglycemia.
Is Januvia a DPP inhibitor?
Januvia belongs to the class of medicines known as DPP-4 inhibitors. It is selective for DPP-4 and does not inhibit DDP-8 or DPP-9 (the inhibition of these two enzymes has been associated with severe toxicity).
Can you take Januvia with food?
Do not take more or less than intended. The usual dosage of Januvia is 100mg once daily. May be taken with or without food. Discontinue Januvia and seek urgent medical advice if unexplained joint pain, skin rash, persistent abdominal pain, unexplained vomiting, or other allergy-type symptoms develop.
Can you take Januvia over the counter?
Talk to a doctor or pharmacist before taking any other medication with Januvia, including that bought over-the-counter, to check that it is compatible with Januvia.
Which drug is in Januvia?
Januvia contains the active drug sitagliptin, and Tradjenta contains the active drug linagliptin.
What type of diabetes is Januvia?
If you have type 2 diabetes, your doctor might prescribe Januvia.
What is Januvia used for?
If you have type 2 diabetes, your doctor might prescribe Januvia. It’s used together with diet and exercise to help manage blood sugar levels in adults with this condition.
How to prevent low blood sugar with Januvia?
To help prevent low blood sugar levels with Januvia, you’ll want to check your blood sugar level. Your doctor will tell you how often to do this. How often you’ll need to check depends on several factors. These include other diabetes drugs you’re taking and whether you’ve had low blood sugar levels in the past.
What to do if you take too much Januvia?
Call your doctor if you think you’ve taken too much Januvia. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource. However, if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room.
Can Januvia cause pancreatitis?
Januvia can cause severe inflammation of the pancreas, which is also called pancreatitis.
What to do if you miss Januvia?
What if I miss a dose of Januvia? If you miss a dose of Januvia, take it as soon as you remember. But if it’s close to your next usual dose of Januvia, skip the missed dose and take your next scheduled dose. If you’re not sure when you should take your next dose of Januvia, ask your doctor or pharmacist.
What other drugs will affect Januvia?
Januvia may not work as well when you use other medicines at the same time. Many other drugs can also affect blood sugar control.
What is Januvia?
Januvia (sitagliptin) is an oral diabetes medicine that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating.
How old do you have to be to use Januvia?
Januvia is not approved for use by anyone younger than 18 years old.
Does Januvia cause shortness of breath?
symptoms of heart failure shortness of breath (even while lying down), swelling in your legs or feet, rapid weight gain. Common Januvia side effects may include: low blood sugar; headache; or. runny or stuffy nose, sore throat. This is not a complete list of side effects and others may occur.
Can Januvia cause back pain?
Stop taking Januvia and call your doctor right away if you have symptoms of pancreatitis: severe pain in your upper stomach spreading to your back, with or without vomiting.
Can you take Januvia if you are allergic to sitagliptin?
You should not use Januvia if you are allergic to sitagliptin, or if you have diabetic ketoacidosis (call your doctor for treatment with insulin ). Tell your doctor if you have ever had: kidney disease (or if you are on dialysis); heart problems; pancreatitis; high triglycerides (a type of fat in the blood);
Can you share Januvia with children?
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Januvia only for the indication prescribed.
SITagliptin food
Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink. You should avoid using alcohol if your diabetes is not well controlled or if you have high triglycerides, neuropathy (nerve damage), or pancreatitis.
Januvia (sitagliptin) disease interactions
There are 2 disease interactions with Januvia (sitagliptin) which include:
