Is Toujeo and Basaglar the same thing?
While Toujeo, Lantus, and Basaglar contain the same active drug, the main difference between them is that Toujeo is more concentrated than either Lantus or Basaglar. So, you can’t use Toujeo in place of Lantus or Basaglar, and you can’t use Lantus or Basaglar in place of Toujeo.
How much should I expect to pay for Toujeo?
Toujeo SoloStar (insulin glargine) is a member of the insulin drug class and is commonly used for Diabetes - Type 1, and Diabetes - Type 2. The cost for Toujeo SoloStar subcutaneous solution (300 units/mL) is around $415 for a supply of 4.5 milliliters, depending on the pharmacy you visit.
Is dosing the same for Lantus and Levemir?
Your initial dose of either drug depends on the specifics of your diabetes. The solution for injection for Levemir and Lantus is 100 units/mL. Both are available in 10-mL vials.
Does Toujeo need needles?
Toujeo must not be drawn from the cartridge of the Toujeo SoloStar pre-filled pen or Toujeo DoubleStar pre-filled pen into a syringe or severe overdose can result (see section 4.4, 4.9 and 6.6). A new sterile needle must be attached before each injection.
Which is better Toujeo and Lantus?
Research shows that Toujeo may offer more consistent blood sugar levels than Lantus, which may reduce the chance of low blood sugar. In fact, according to one study, those who use Toujeo are 60 percent less likely to have severe hypoglycemic incidents than people taking Lantus.
Is it better to take Toujeo in the morning or at night?
You can administer Toujeo any time of the day or night, but preferably it should be given at approximately the same time every day.
Is Toujeo more concentrated than Lantus?
Toujeo and Lantus are both long-acting insulin glargine, but are not the same prescription product. Toujeo is insulin glargine in a concentration of 300 units/ml, and Lantus is in a concentration of 100 units/ml. Toujeo is only available in prefilled pens, while Lantus is available in both prefilled pens and vials.
What is a substitute for Toujeo?
What should I know about alternatives to Toujeo?Active ingredientAges approved forTresibainsulin degludecadults and children ages 1 year and olderBasaglarinsulin glargineadults and children ages 6 years and olderLevemirinsulin detemiradults and children ages 2 years and older1 more row
Why does Toujeo cause weight gain?
Weight gain has occurred with some insulin therapies including TOUJEO and has been attributed to the anabolic effects of insulin and the decrease in glucosuria.
How many units of Lantus is normal?
Dosage for type 2 diabetes For people with type 2 diabetes who aren't currently taking insulin, the recommended starting dosage of Lantus is 0.2 units/kg or 10 units once per day. The maximum starting dosage of Lantus is 10 units per day.
Can I substitute Lantus for Toujeo?
Because the pen has been calibrated in such a way as to draw up smaller volumes, the dosage conversion from Lantus to Toujeo is still 1:1. For example, if your doctor prescribed you 22 units of Lantus and you changed to Toujeo, your initial dose would be 22 units of Toujeo.
What is a good substitute for Lantus?
Semglee (insulin glargine-yfgn) is both biosimilar to, and interchangeable with (can be substituted for), its reference product Lantus (insulin glargine), a long-acting insulin analog. Semglee (insulin glargine-yfgn) is the first interchangeable biosimilar product approved in the U.S. for the treatment of diabetes.
Is there a better insulin than Lantus?
Toujeo and Lantus are long-acting insulins that can help keep your blood sugar controlled for 24 hours or longer. Toujeo is more concentrated than Lantus and may be a good option for people who need higher amounts of insulin.
How do you convert Toujeo to Lantus?
Consider conversion as for Lantus, given Lantus/Basaglar dose equivalency. NPH twice daily: reduce total daily dose by 20% and give Lantus, Basaglar, Semglee, or Toujeo once daily. May take ≥5 days to see the max effect of the selected dose of Toujeo. Do not increase dose more often than every 3 to 4 days.
Which is the best insulin?
What Type of Insulin Is Best for My Diabetes?Type of Insulin & Brand NamesOnsetPeakLong-ActingInsulin glargine (Basaglar, Lantus, Toujeo)1-1 1/2 hoursNo peak time. Insulin is delivered at a steady level.Insulin detemir (Levemir)1-2 hours6-8 hoursInsulin degludec (Tresiba)30-90 min.No peak time16 more rows•Aug 25, 2022
Does Toujeo lower blood sugar?
The most common side effect of any insulin, including Toujeo, is low blood sugar (hypoglycemia), which may be serious and life-threatening. Severe hypoglycemia may cause harm to your heart or brain. Symptoms of serious low blood sugar may include shaking, sweating, fast heartbeat, and blurred vision.
Does Toujeo make you sleepy?
Toujeo is used to treat diabetes, and this condition may cause fatigue. Sleepiness can be a symptom of fatigue. Other symptoms of fatigue include muscle aches, irritability, and trouble concentrating. If you feel sleepy or have other symptoms of fatigue while using Toujeo, talk with your doctor.
Can Toujeo be used twice a day?
Even though Toujeo is usually given once a day, some people may experience better blood sugar control if the dose is split and given twice a day (every 12 hours). Those that tend to benefit from twice-daily Toujeo include those experiencing early morning hypoglycemia or persistent hyperglycemia at dinner time.
How long does it take Toujeo to start working?
It may take up to 5 days for Toujeo to have its full effect on lowering your blood sugar levels. Dosage adjustments should only be made every 3 or 4 days.
Can you take metformin and Toujeo together?
Can you take Toujeo (insulin glargine) and metformin together? Toujeo (insulin glargine) can be taken with other oral diabetes medications, like metformin, if your blood sugar level needs better control.
What is the difference between Toujeo and Lantus?
The biggest difference is that Toujeo is highly concentrated, making injection volume much smaller than Lantus.
What is Toujeo and Lantus?
Overview. Toujeo and Lantus are long-acting insulin used to manage diabetes. They are brand names for the generic insulin glargine. Lantus has been one of the most commonly used long-acting insulins since it became available in the year 2000. Toujeo is relatively new, and only entered the market in 2015.
How many units of Toujeo are in a milliliter?
While Lantus contains 100 units per milliliter, Toujeo is three times more concentrated, yielding 300 units per milliliter (U100 versus U300, respectively) of fluid. However, this doesn’t mean you should take a lower dosage of Toujeo than you would take of Lantus.
Why do you need fewer Toujeo injections than Lantus?
If you need a high dose of insulin, you may need fewer injections with Toujeo than you would need with Lantus, simply because the Toujeo pen can hold more.
Why is Toujeo a lesser volume?
The Toujeo will only appear to be a lesser volume within the pen because it is immersed in a smaller amount of carrier liquid. It’s like getting the same amount of caffeine in a tiny shot of espresso or a large latte.
Does Toujeo lower A1C?
Both Toujeo and Lantus effectively lower hemoglobin A1C numbers , which represent an average blood glucose level over time. While those averages may be the same on either formula, Sanofi claims that Toujeo provides more consistent blood sugar levels throughout the day, which may result in fewer ups and downs in energy, mood, alertness, and hunger levels.
Is Toujeo available in vials?
Lantus is also available in vials for use with syringes. Toujeo is not.
What are the side effects of Toujeo and Lantus?
The main side effect of any insulin, including Toujeo and Lantus, is hypoglycemia (low blood sugar). Symptoms of hypoglycemia include:
How many units of insulin are in a milliliter of Toujeo?
Toujeo and Lantus also differ in their concentration of insulin glargine. Insulin is often supplied in vials or insulin pens to be injected. For most insulins, including Lantus, 1 milliliter (mL) has 100 units (U) of insulin in it. But Toujeo is a much more concentrated form, with 300 units of insulin glargine per milliliter.
Do Toujeo and Lantus differ in how you take them?
Lantus and Toujeo are both injected into the body (generally around the stomach subcutaneously) and slowly absorbed.
Do Toujeo and Lantus interact with any other drugs?
Many drugs can interact with Toujeo and Lantus and increase your risk of hypoglycemia, high blood sugar (hyperglycemia), or other side effects. The following are some drugs to watch out for, but this is not an all-inclusive list:
How many units of insulin does a Toujeo pen hold?
Toujeo, on the other hand, is only available as a pen, but there are 2 kinds: the Toujeo SoloStar and the Toujeo SoloStar Max. The SoloStar holds 450 units of insulin per pen, and the SoloStar Max holds 900 units of insulin per pen.
How much Toujeo should I take a day?
For people who need more insulin than average, this could be seen as an advantage. With Toujeo, you’ll only ever need 1 dose per day , whereas with less concentrated insulins (i.e., Lantus, Levemir, Basaglar), you may need 2 doses per day, either at the same time or split up depending on how your blood sugar levels respond.
Is Toujeo a good insulin?
Toujeo and Lantus are long-acting insulins that can help keep your blood sugar controlled for 24 hours or longer. Toujeo is more concentrated than Lantus and may be a good option for people who need higher amounts of insulin. Both medications can be expensive, but you may be able to use insurance, pharmacy coupons, copay cards, and patient assistance programs to reduce the cost.
What is the difference between Toujeo and Lantus?
The biggest difference is that Toujeo is highly concentrated, making injection volume much smaller than Lantus. Now that we have looked at the short answer as to whether Lantus or Toujeo is best, let’s first take a look at an overview of each, starting with Lantus.
Who makes Toujeo and Lantus?
Toujeo and Lantus are manufactured by Sanofi. Both of these drugs are designed to support diabetes, and both are long-lasting human-made insulins.
How long does Toujeo last after opening?
Once Lantus is opened, it can last 28 days at room temperature. On the other hand, Toujeo can last up to 56 days after it has been opened.
How many insulin units does Toujeo have?
Toujeo has two insulin pen options available. One which contains 450 units and the other larger capacity pen which has 900 units.
What are the side effects of Lantus?
More serious side effects that either Lantus or Toujeo may cause may include: Severe allergic reaction. Seek immediate medical attention if you begin to have signs of an allergic reaction, such as rash, trouble breathing, rapid heartbeat, or sweating. Low potassium in your blood (hypokalemia) Heart failure.
How long does Lantus work?
It is the brand name of insulin glargine. Lantus begins working around four hours after injection, and it helps control blood sugar levels for up to 24 hours. According to the Lantus dosage and administration guide, it can be administered at any time of the day, once a day.
When did Lantus become available?
Lantus has been one of the most commonly used long-acting insulins since it became available in 2000. Toujeo is relatively new and only entered the market in 2015.
The Main Difference between Lantus & Toujeo
Both drugs contain long-acting insulin glargine used to treat and manage Diabetes Type-1 and Type-2.
Lantus Vs. Toujeo in Doses
Lantus contains 100 units per milliliter, and Toujeo is three times more concentrated,300 units per milliliter.
Lantus Vs. Toujeo in Effectiveness
Toujeo and Lantus effectively lower HBA1C numbers. However, while they’re effective in results, toujeo gives more long half-life and stays in the body, providing a steady glucose level than Lantus.
Lantus Vs. Toujeo in Side effects
Toujeo can provide more consistent blood sugar levels than Lantus, reducing the chance of shallow sugars in the blood. According to a study, those who use Toujeo, 60% of them not suffer from severe hypoglycemic incidents than people taking Lantus.
Summary
If you are currently taking Lantus and are satisfied with its results, it is unnecessary to switch to Toujeo. However, Toujeo has advantages over Lantus if someone experiences blood sugar fluctuations or frequently experiences hypoglycemic shocks or episodes.
What are the most common adverse events of Toujeo?
Most common adverse events (with incidence ≥5%) with Toujeo in patients with T2DM were nasopharyngitis (7.1%) and upper respiratory tract infection (5.7%). 1
How long is Toujeo steady state?
Clamp Study I: The pharmacodynamics of Toujeo at steady state after 8 days of daily injections was evaluated against Lantus in a euglycemic clamp study of patients with T1DM (N=30) receiving injections of 0.4 U/kg once daily. The dose on day 8 was followed by a 36-hour euglycemic clamp. 2
Insulin Glargine U-300 (Toujeo) vs Lantus Solostar
Toujeo vs Lantus Solostar - The differences are minute but may be of immense significance in certain patients. Insulin Glargine U-300, available by the brand name of Toujeo is the concentrated form of Insulin Glargine U-100 (Lantus Solostar).
What are the advantages of Insulin Glargine U-300 over Lantus Solostar ( Glargine U-100)?
Lantus (Glargine U-100) and Toujeo (U-300) contains the same insulin, so there is essentially no difference as far as the chemical formulation is concerned. However, the following are some of the important differences between Toujeo and Lantus:
My experience with Glargine U-300 (Toujeo) and empagliflozin
This is a 52 years of age patient with type 2 diabetes mellitus weighing 74 kgs. She presented with blood sugars ranging from 170 - 250 mg/dl in the fasting state and 200 - 400 mg in the prandial (Post-meals) state. She was using:
