
Precautions
What should I avoid while taking sucralfate?
- antacids
- cimetidine
- digoxin
- ketoconazole
- levothyroxine
- phenytoin
- quinidine
- fluoroquinolone antibiotics, such as ciprofloxacin
- ranitidine
- tetracycline
What should I avoid while taking sucralfate?
There are approximately 14 to 16 mEq of acid-neutralizing capacity per 1 g dose of sucralfate. In a multicenter, double-blind, placebo-controlled study of CARAFATE Oral Suspension, a dosage regimen of 1 gram (10 mL) four times daily was demonstrated to be superior to placebo in ulcer healing. * P =0.016 † P =0.001 ‡ P =0.0001
How much sucralfate should be taken?
Side effects requiring immediate medical attention
- Blue lips and fingernails
- blurred vision
- chest pain
- cough
- coughing that sometimes produces a pink frothy sputum
- difficult, fast, noisy breathing
- difficulty in swallowing
- dry mouth
- feeling of fullness
- flushed, dry skin
What are possible side effects of sucralfate?
- Constipation is the main reported side effect in 2 percent of people taking this medicine. ...
- It may not be recommended to people who have conditions that cause difficulty swallowing or a previous history of aspiration.
- After oral intake, small amounts of aluminum are absorbed since sucralfate contains aluminum. ...
What are the most common sucralfate side effects?
See more

Does sucralfate help with stomach pain?
Sucralfate administration was accompanied by the disappearance of heartburn, epigastric pain, epigastric distress, or epigastric burning in 42 of 59 occurrences, and by statistically significant reductions in bloating. There was a trend toward significance in decreased nocturnal abdominal pain and in belching.
How long does it take for sucralfate to work?
Just know that sucralfate (Carafate) is protecting your GI tract so that it can heal the ulcer, but it may take up to 4 to 8 weeks before you receive the full benefit of taking sucralfate (Carafate).
Can sucralfate be used for acid reflux?
Sucralfate is effective for the treatment of human reflux oesophagitis1,2,3,4; however, current first-line treatments for gastroesophageal reflux disease (GERD) are proton pump inhibitors (PPIs) which control gastric acid secretion.
Does sucralfate heal gastritis?
Abstract. Sucralfate is a cytoprotective drug widely used in clinical practice to prevent or treat several gastrointestinal diseases such as gastro-esophageal reflux, gastritis, peptic ulcer, stress ulcer and dyspepsia.
What should you avoid when taking sucralfate?
Common medications whose absorption may be affected by sucralfate include:antibiotics such as ciprofloxacin, gemifloxacin, ketoconazole, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, or tetracycline.aspirin.cimetidine.digoxin.l-thyroxine (levothyroxine)More items...•
What is the most common side effect of sucralfate?
Constipation. The most common side effect of sucralfate is constipation. The medication works by binding to ulcers to protect them from further exposure to stomach acid, bile, pepsin, and bile salts. This gives the ulcers time to heal.
Do I have to eat after taking sucralfate?
If you are taking sucralfate to treat ulcers, the tablets or liquid usually are taken four times a day. If you are taking sucralfate to prevent an ulcer from returning after it has healed), the tablets usually are taken twice a day. Take sucralfate on an empty stomach, 2 hours after or 1 hour before meals.
Which is better omeprazole or sucralfate?
Omeprazole was significantly superior to sucralfate in inducing gastric ulcer healing after both 4 (87 vs. 52%, P = 0.007) and 8 weeks (100 vs. 82%, P = 0.04). No statistically significant difference in duodenal ulcer healing rates emerged between the two groups either at 4 (79 vs.
How much water should you drink with sucralfate?
For patients with difficulty swallowing whole or halved sucralfate tablets, a slurry may be prepared just prior to administration by placing a 1 gram tablet in a 30 mL medicine cup without crushing and adding 15 mL to 30 mL of water, preferably warm water but room temperature is adequate.
What foods heal stomach lining?
Some people find that the following foods and drinks help ease symptoms of gastritis: high fiber foods, such as whole grains, fruits, vegetables, and beans. low fat foods, such as fish, lean meats, and vegetables. foods with low acidity, including vegetables and beans....These include:kombucha.yogurt.kimchi.sauerkraut.
What is gastritis caused by?
Gastritis is a redness and swelling (inflammation) of the stomach lining. It can be caused by drinking too much alcohol, eating spicy foods, or smoking. Some diseases and other health issues can also cause gastritis.
Can I drink water before taking sucralfate?
Take this medication by mouth with a glass of water. Follow the directions on the prescription label. This medication works best if you take it on an empty stomach, 1 hour before meals.
How effective is sucralfate?
The efficacy of sucralfate 1g qid in DU and GU healing has been amply confirmed in placebo and cimetidine or ranitidine-controlled studies. Healing rates have been reported in 60 to 83% DU patients after 4 weeks treatment with sucralfate but as with other drugs the rates tend to be lower in GU patients.
Does sucralfate really work?
Sucralfate is used to treat and prevent duodenal ulcers and other conditions as determined by your doctor. It works by forming a barrier or coat over the ulcer. This protects the ulcer from the acid of the stomach, allowing it to heal.
How soon can I eat after taking sucralfate?
If you are taking sucralfate to prevent an ulcer from returning after it has healed), the tablets usually are taken twice a day. Take sucralfate on an empty stomach, 2 hours after or 1 hour before meals.
Why should sucralfate be taken on an empty stomach?
Sucralfate It works by forming a protective coating over the ulcer. Sucralfate must be taken on an empty stomach. This means at least 1 hour before or 2 hours after a meal. If it's taken with food, the medication may not coat the ulcer properly.
Before Taking This Medicine
You should not use sucralfate if you are allergic to it.To make sure sucralfate is safe for you, tell your doctor if you have: 1. diabetes; 2. kidn...
How Should I Take Sucralfate?
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.Take sucral...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember, but avoid taking any other medications within 2 hours before or after you take sucralfate. Skip the m...
What Should I Avoid While Taking Sucralfate?
Avoid taking any other medications within 2 hours before or after you take sucralfate. Sucralfate can make it harder for your body to absorb other...
Sucralfate Dosing Information
Usual Adult Dose for Duodenal Ulcer:1 g orally 4 times a day-Duration of therapy: 4 to 8 weeksComments:-Each dose should be taken on an empty stoma...
What Other Drugs Will Affect Sucralfate?
Sucralfate can make it harder for your body to absorb other medications you take by mouth. Avoid taking any other medications within 2 hours before...
What is the drug sucralfate (Carafate) used for?
Sucralfate (Carafate) is FDA-approved for the treatment and management of duodenal ulcers (ulcers that are located in the first part of the small i...
How long does it take for sucralfate (Carafate) take to work?
The medication will start to work and create a lining as soon as it reaches your GI tract (usually within an hour). Unlike other ulcer medications,...
Can I take omeprazole (Prilosec) and sucralfate (Carafate) together?
Many people with ulcers will also be prescribed other medications to lower the amount of acid in their stomach. Since sucralfate (Carafate) can aff...
When can I stop taking sucralfate (Carafate)?
The length of treatment will depend on your ulcer and how quickly it heals. Your provider will monitor the healing process and make adjustments to...
What happens if I take sucralfate (Carafate) with food?
It's recommended to take sucralfate (Carafate) on an empty stomach so that the medication can work locally at the site of the ulcer. If your stomac...
What is sucralfate (Carafate)?
Sucralfate (Carafate) is an antiulcer medication that protects the gastrointestinal (GI) tract. It lines the stomach and small intestine, which forms a protective barrier around the ulcer to allow the ulcer to heal.
What are the side effects of sucralfate (Carafate)?
With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.
How to treat ulcers on stomach?
Take sucralfate (Carafate) on an empty stomach with plenty of water. This will help the medication work quickly at the site of the ulcer. If you also take antacids like Tums or Maalox to help with ulcer pain, make sure you take them at least 30 minutes before or after sucralfate (Carafate).
How long does it take for sucralfate to work?
Just know that sucralfate (Carafate) is protecting your GI tract so that it can heal the ulcer, but it may take up to 4 to 8 weeks before you receive the full benefit of taking sucralfate (Carafate).
Can sucralfate be used in elderly?
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sucralfate in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.
Can you take carafate on an empty stomach?
If your stomach has food in it, the medication will bind to the food instead of the lining on your GI tract. When this happens, sucralfa te (Carafate) isn't able to create a protective barrier.
Can you stop sucralfate?
Your provider will monitor the healing process and make adjustments to your dose. Don't stop taking sucralfate (Carafate) without consulting with your healthcare provider as it may impact the ulcer healing process.
What is sucralfate used for?
Sucralfate is used to treat and prevent the return of duodenal ulcers ( ulcers located in first part of the small intestine). Treatment with other medications, such as antibiotics, may also be necessary to treat and prevent the return of ulcers caused by a certain type of bacteria (H. pylori) Sucralfate is in a class of medications called ...
How long does sucralfate take to heal?
Shake the liquid well before each use to mix the medication evenly. This medicine must be taken regularly to be effective. It may take up to 8 weeks for ulcers to heal.
How should this medicine be used?
Sucralfate comes as a tablet and liquid to take by mouth. If you are taking sucralfate to treat ulcers, the tablets or liquid usually are taken four times a day. If you are taking sucralfate to prevent an ulcer from returning after it has healed), the tablets usually are taken twice a day. Take sucralfate on an empty stomach, 2 hours after or 1 hour before meals. Take sucralfate around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sucralfate exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
What should I know about storage and disposal of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not freeze sucralfate liquid.
What to do if you are allergic to sucralfate?
tell your doctor and pharmacist if you are allergic to sucralfate, any other medications, or any of the ingredients in sucralfate tablets or liquid. Ask your pharmacist for a list of the ingredients.
Can you get pregnant while taking sucralfate?
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking sucralfate, call your doctor.
Can sucralfate cause constipation?
constipation. Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment: hives. rash. itching. difficulty breathing or swallowing. swelling of the face, throat, tongue, or lips. Sucralfate may cause other side effects.
What is sucralfate used for?
This medication is used to treat and prevent ulcers in the intestines. Sucralfate forms a coating over ulcers, protecting the area from further injury. This helps ulcers heal more quickly.
How long does sucralfate last?
Inform your doctor if your condition persists or worsens after you have been taking sucralfate for 4 weeks. Side Effects. Constipation, dry mouth, upset stomach, gas, and nausea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
How to report sucralfate side effects in Canada?
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Precautions. Before taking sucralfate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
Can you take sucralfate while pregnant?
If you are pregnant, tell your doctor before using sucralfate. It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding. Drug interactions may change how your medications work or increase your risk for serious side effects.
Are you currently using sucralfate oral?
This survey is being conducted by the WebMD marketing sciences department.
What is sucralfate used for?
Sucralfate, sold under various brand names, is a medication used to treat stomach ulcers, gastroesophageal reflux disease (GERD), radiation proctitis, and stomach inflammation and to prevent stress ulcers. Its usefulness in people infected by H. pylori is limited. It is used by mouth (for upper GIT ulcers) and rectally (for radiation proctitis).
When was sucralfate approved?
Sucralfate was approved for medical use in the United States in 1981. It is available as a generic medication. In 2017, it was the 218th most commonly prescribed medication in the United States, with more than two million prescriptions.
What is the brand name of Sucral?
Brand names include Carafate in U.S.A., Sucramal in Italy, Sucrafil, Sufrate, Sucralpro, Sucralcoat, Pepsigard, Sucral, Hapifate, Sucralpro in India, Sutra or Musin in parts of South-East Asia, Sulcrate in Canada, Discral (sucralfato) in México, Ulsanic in South Africa and Israel, Andapsin in Sweden and Antepsin. Sucracell in India.
How long does sucralfate act as a buffer?
Sucralfate is a locally acting substance that in an acidic environment (pH < 4) reacts with hydrochloric acid in the stomach to form a cross-linking, viscous, paste-like material capable of acting as an acid buffer for as long as 6 to 8 hours after a single dose.
Is sucralfate used for peptic ulcers?
The use for sucralfate in peptic ulcer disease has diminished recently, but it is still the preferred agent for stress ulcer prevention. Sucralfate has also been used for the following conditions: Active duodenal ulcer not related to NSAID use. Maintenance therapy for resolved duodenal ulcers.
Does sucralfate stimulate gastric mucus?
It has been thought that sucralfate also stimulates the production of prostaglandin E 2, epidermal growth factors (EGF), bFGF, and gastric mucus.
Does sucralfate affect pH?
Sucralfate may be considered to have the advantage over H2-blockers and PPIs in this regard because sucralfate does not change the pH of gastric fluid. A majority of meta-analyses found that sucralfate therapy decreased the incidence of ventilator-associated pneumonia compared to H2-antagonists.
WHAT IS Sucralfate?
Sucralfate is an oral gastrointestinal medication primarily indicated for the treatment of active duodenal ulcers.
Product Info
The sections below will provide you with more specific information and guidelines related to fluoxetine and its correct use. Please read them carefully.
Product Images
Below you will find images and specific information on the principal types of sucralfate that exist, including their respective brand name (s), strength, inscription codes, manufacturers and/or distributors.
What are some things I need to know or do while I take Sucralfate Tablets?
Tell all of your health care providers that you take this medicine (sucralfate tablets). This includes your doctors, nurses, pharmacists, and dentists.
What are some other side effects of Sucralfate Tablets?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
How long before taking sucralfate can you take antacids?
Follow all instructions closely. Take on an empty stomach. Do not take antacids 30 minutes before or after taking this medicine (sucralfate tablets). Try to space other drugs from this one by 2 hours. This medicine stops many drugs from getting into the body.
What to do if you have questions about sucralfate?
Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine (sucralfate tablets), please talk with your doctor, nurse, pharmacist, or other health care provider.
Can you take Sucralfate if you are 65?
If you are 65 or older, use this medicine (sucralfate tablets) with care. You could have more side effects. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
Can you take sucralfate with all your medications?
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (sucralfate tablets) with all of your drugs and health problems.
What is the purpose of sucralfate film?
This film acts as a barrier to gastric acid, pepsin (one of the main digestive enzymes), and bile salts. Sucralfate belongs to the class of medicines known as disaccharide sulfates. It is also known as a protectant anti-ulcer medicine. 2. Upsides.
What are the side effects of sucralfate?
Constipation is the main side effect reported (in 2% of people); other side effects include diarrhea, nausea, itch, rash, and dry mouth. Generally, side effects are relatively rare (only reported in 4.7% of people who take sucralfate). Rarely, allergic reactions and bezoars (an accumulation of indigestible material in the gastrointestinal tract) ...
How much acid does sucralfate neutralize?
Each 1g dose of sucralfate neutralizes approximately 14 to 16 mEq of stomach acid.
How long does sucralfate last?
Sucralfate forms a complex with the albumin exudate of the ulcer soon after tablet dissolution. One dose lasts approximately 6 hours.
How long before sucralfate can you take digoxin?
May reduce the absorption of some drugs including digoxin, fluoroquinolone antibiotics, phenytoin, and thyroxine. These drugs should be taken at least two hours before taking sucralfate. Usually taken four times daily for ulcer treatment and twice daily for ulcer maintenance.
What medications are affected by sucralfate?
Common medications whose absorption may be affected by sucralfate include: antibiotics such as ciprofloxacin, gemifloxacin, ketoconazole, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, or tetracycline. aspirin. cimetidine. digoxin.
Can you share sucralfate with children?
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use sucralfate only for the indication prescribed.

Overview
This medication is used to treat and prevent ulcers in the intestines.
May Treat: Duodenal ulcer · Gastroesophageal reflux disease · Maintenance of healing duodenal ulcer
Brand Names: Carafate
Drug Class: Peptic Ulcer - Gastric Lumen Adherent Cytoprotectives
Availability: Prescription Required
Pregnancy: Consult your doctor
Lactation: Consult a doctor before using
Medical uses
Side effects
Mechanism of action
Pharmacokinetics
Sucralfate, sold under various brand names, is a medication used to treat stomach ulcers, gastroesophageal reflux disease (GERD), radiation proctitis, and stomach inflammation and to prevent stress ulcers. Its usefulness in people infected by H. pylori is limited. It is used by mouth(for upper GIT ulcers) and rectally(for radiation proctitis).
Brand names
Sucralfate is used for the treatment of active duodenal ulcers not related to the use of nonsteroidal anti-inflammatory drugs (NSAIDs), as the mechanism behind these ulcers is due to acid oversecretion. It is not FDA approved for gastric ulcers, but is widely used because of evidence of efficacy. The use for sucralfate in peptic ulcer disease has diminished recently, but it is still the preferred agent for stress ulcer prevention.
External links
The most common side effect seen is constipation (2-3%). Less commonly reported side effects (<0.5%) include flatulence, headache, hypophosphatemia, xerostomia (dry mouth), and bezoar formation. Use of this drug is not recommended for people with chronic kidney failure, as it might cause aluminium accumulation and toxicity. A few well-controlled studies have been carried out investigating the safety and efficacy of sucralfate in children and pregnant women (Pregnancy C…