by Melyna Schaefer
Published 3 years ago
Updated 2 years ago
The primary function of the loops of Henle and the thick ascending limb of the distal tubule is the concentration of urine utilizing a principle called 'countercurrent multiplication.' The medulla possesses a gradient of urea and salt with increasing concentrations of these solutes closer to the papillae.
What are the three major functions of the loop of Henle?
Regulating potassium, calcium and magnesium excretion at the lowest energy costs. Homeostasis of the acid-base balance via bicarbonate and ammonia excretion.
How does the loop of Henle produce urine?
Water present in the filtrate in the papillary duct flows through aquaporin channels out of the duct, moving passively down its concentration gradient. This process reabsorbs water and creates a concentrated urine for excretion.
What is reabsorbed in loop of Henle?
The loop of Henle is the site of the majority of magnesium absorption from the kidneys. Approximately 60% to 70% of filtered magnesium is reabsorbed in the cortical thick ascending limb of the loop of Henle.
What are mainly reabsorbed from Henle's loop?
The Henle's loop of nephron is mainly responsible for reabsorption of water in the kidney.
What does the loop of Henle prevent UTI?
Uromodulin (also known as Tamm–Horsfall urinary glycoprotein) is specifically produced in the urinary tract by epithelial cells lining the ascending limb of Henle's loop in kidney nephrons16.
Which part of the nephron concentrates the urine?
The renal medulla produces concentrated urine through the generation of an osmotic gradient extending from the cortico-medullary boundary to the inner medullary tip.
Where hydrogen and potassium ions are secreted into the urine?
Secretion, which occurs in the proximal tubule section of the nephron, is responsible for the transport of certain molecules out of the blood and into the urine. Secreted substances include potassium ions, hydrogen ions, and some xenobiotics.
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