Precautions
The biggest thing to know, related to vitamin supplementation while taking this medications involves your vitamin D levels. Long term use of phenytoin (Dilantin) can deplete your vitamin D levels leading to the potential for other problems.
Can you take vitamin supplements with phenytoin (Dilantin)?
According to an abstracted article from the University of Maryland, it is important to take Dilantin and foods with calcium or calcium supplements 2 hours apart to promote increased absorption of both Dilantin and calcium. This amazing kale pesto is only 210 calories and anti-oxidant rich!
Can you take Dilantin and calcium together?
In adults, if seizure control is established with divided doses of three 100-mg Dilantin (extended phenytoin sodium capsules, USP) daily, once-a-day dosage with 300 mg of Dilantin (extended phenytoin sodium capsules, USP) may be considered.
How many Dilantin can you take in a day?
Some Fruits and Vegetables. Synthetic folate, also called folic acid, is available in pill and injectible form, and may be used to prevent folic acid deficiency in patients taking Dilantin. Folic acid is metabolized more readily without interference with Dilantin.
Can you take folic acid with Dilantin?
Can I take vitamin d3 with DILANTIN?
phenytoin cholecalciferol Using phenytoin together with cholecalciferol may decrease the effects of cholecalciferol. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications.
Can I take calcium and DILANTIN?
Interactions between your drugs Using calcium carbonate together with phenytoin may decrease the effects of phenytoin. Separate the times of administration of calcium carbonate and phenytoin by at least two to three hours.
What vitamin does phenytoin affect?
The widely practised antiepileptic drug for this disease is Phenytoin. The long-term treatment of this drug develops a deficiency of Folate and Vitamin B12 which in turn promotes anaemia to a significant degree3.
Can you take vitamin C with DILANTIN?
No interactions were found between phenytoin and Vitamin C.
Can you take magnesium with seizure medication?
No, Magnesium Sulfate Should Not Be Used in Treating Eclamptic Seizures.
Why is folic acid given with phenytoin?
Conclusions: Folic acid supplementation should be initiated each time phenytoin therapy commences because of the hypothesized cofactor mechanism, decreased adverse effects associated with folate deficiency, and better seizure control with no perturbation of phenytoin pharmacokinetics.
Can you take calcium with phenytoin?
Aluminum hydroxide, magnesium hydroxide, and calcium may bind to phenytoin in your digestive tract, preventing your body from absorbing your phenytoin.
Does phenytoin affect vitamin D?
Calcium and vitamin D metabolism were evaluated in 5 adult epileptic patients before and during treatment with phenytoin. Significant decreases occurred in serum concentrations of calcium, albumin, and 25-hydroxy-cholecalciferol.
Why is vitamin B complex is given in phenytoin?
Supplementation of phenytoin with folic acid or combination of these vitamins may be recommended for the purpose of ameliorating the adverse biochemical changes which are associated with phenytoin therapy.
What supplements should not be taken together?
Here are six vitamin combinations you definitely shouldn't take together.Magnesium and calcium/multivitamin. ... Vitamins D, E and K. ... Fish Oil & Gingko Biloba. ... Copper and zinc. ... Iron and Green tea. ... Vitamin C and B12.
What should you avoid when taking phenytoin?
Other Interactions Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur.
What vitamins Cannot be taken together?
Some vitamins that should not be taken together, or have dosage limitations, include vitamin C with vitamin B-12, vitamin A supplement with vitamin A-rich foods, folic acid (vitamin B9) and vitamin B12, and vitamin E with vitamin K.
What drugs should not be taken with calcium?
Calcium can decrease the absorption of other drugs such as tetracycline antibiotics (for example, doxycycline, minocycline), bisphosphonates (such as alendronate), estramustine, levothyroxine, and quinolone antibiotics (such as ciprofloxacin, levofloxacin).
What should not be taken with calcium?
Avoid taking calcium supplements with very high fiber meals. Fiber can bind with calcium, reducing the amount available to your body. Don't take more than 500 to 600 mg at a time – your body is not able to absorb much more and it will be excreted in the urine.
Can you take calcium with prescription meds?
Calcium supplements can interact with many prescription medicines, including antibiotics, bisphosphonates and high blood pressure medications. Ask your doctor or pharmacist about possible interactions between calcium supplements and your medications.
What medications interfere with calcium absorption?
Common culprits include medications used to treat heartburn and “gastroesophageal reflux disorder” (GERD), such as omeprazole (Prilosec), lansoprazole (Prevacid), and esomeprazole (Nexium). These medications decrease the production of stomach acid, which leads to decreased calcium absorption.
Before Taking This Medicine
You should not use Dilantin you are allergic to phenytoin or similar medicines such as ethotoin (Peganone), fosphenytoin (Cerebyx), or mephenytoin...
How Should I Take Dilantin?
Take Dilantin exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smalle...
What Happens If I Miss A Dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to...
What Happens If I Overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of phenytoin can be fatal. Overdose symptoms may inclu...
What Should I Avoid While Taking Dilantin?
Avoid drinking alcohol while you are taking Dilantin. Alcohol use can increase your blood levels of phenytoin and may increase side effects. Daily...
Dilantin Dosing Information
Usual Adult Dose for Seizures:Oral (except suspension) Loading dose: Only when indicated for inpatients.1 g orally divided in 3 doses (400 mg, 300...
What Other Drugs Will Affect Dilantin?
Sometimes it is not safe to use certain medications at the same time. Some drugs can raise or lower your blood levels of phenytoin, which may cause...
How to take dilantin?
Take Dilantin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Swallow an extended-release capsule whole and do not crush, chew, break, or open it.
What are the side effects of dilantin?
Common Dilantin side effects may include: drowsiness, confusion; slurred speech; abnormal eye movement; or. problems with balance, coordination, or muscle movement. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
What is the drug used to treat seizures?
Dilantin ( phenytoin) is an anti-epileptic drug, also called an anticonvulsant. It works by slowing down impulses in the brain that cause seizures. Dilantin is used to control seizures. Phenytoin does not treat all types of seizures, and your doctor will determine if it is the right medicine for you.
Can you stop dilantin if you have seizures?
Tell your doctor if Dilantin does not seem to work as well in controlling your seizures. Do not stop using Dilantin suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose.
Can you take dilantin if you are allergic to phenytoin?
You should not use Dilantin if you are allergic to phenytoin, or if you have ever had: liver problems caused by phenytoin; an allergy to similar medicines such as ethotoin, fosDilantin, or meDilantin; or. if you currently take delavirdine (Rescriptor).
Can phenytoin cause a seizure?
Phenytoin may harm an unborn baby, but having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant while taking this medicine. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of phenytoin on the baby.
Does dilantin cause hives?
Dilantin side effects. Get emergency medical help if you have signs of an allergic reaction to Dilantin ( hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
How many doses of dilantin are there?
Initially, one gram of Dilantin (extended phenytoin sodium capsules, USP) is divided into three doses ( 400 mg, 300 mg, 300 mg) and administered at two-hour intervals. Normal maintenance dosage is then instituted 24 hours after the loading dose, with frequent serum level determinations.
What is dilantin used for?
Dilantin is indicated for the treatment of tonic-clonic (grand mal) and psychomotor (temporal lobe) seizures and prevention and treatment of seizures occurring during or following neurosurgery.
How long does it take for dilantin to reach steady state?
For Dilantin capsules, peak serum levels occur 4 to 12 hours after administration. Steady-state therapeutic levels are achieved at least 7 to 10 days (5–7 half-lives) after initiation of therapy with recommended doses of 300 mg/day. When serum level determinations are necessary, they should be obtained at least 5–7 half-lives after treatment initiation, dosage change, or addition or subtraction of another drug to the regimen so that equilibrium or steady-state will have been achieved.
What is the free acid form of phenytoin?
Switching Between Phenytoin Formulations. The free acid form of phenytoin is used in Dilantin-125 Suspension and Dilantin Infatabs. Dilantin extended capsules and parenteral Dilantin are formulated with the sodium salt of phenytoin.
What is the color of the PD on a dilantin capsule?
Capsule is imprinted with black rectified radial print, "PD" on cap and "Dilantin 30 mg" on body. 100 mg: hard, filled No. 3 capsules with a white, opaque body and a medium orange cap containing a white powder. Capsule is imprinted with black rectified radial print, "PD" on cap and "Dilantin 100 mg" on body.
Can dilantin be discontinued?
Angioedema has been reported in patients treated with Dilantin in the postmarketing setting. Dilantin should be discontinued immediately if symptoms of angioedema , such as facial, perioral, or upper airway swelling occur. Dilantin should be discontinued permanently if a clear alternative etiology for the reaction cannot be established.
Can phenytoin be taken with status epilepticus?
Abrupt withdrawal of phenytoin in epileptic patients may precipitate status epilepticus. When, in the judgment of the clinician, the need for dosage reduction, discontinuation, or substitution of alternative anticonvulsant medication arises, this should be done gradually. However, in the event of an allergic or hypersensitivity reaction, more rapid substitution of alternative therapy may be necessary. In this case, alternative therapy should be an anticonvulsant drug not belonging to the hydantoin chemical class.
Severe Interactions
These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
Serious Interactions
These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
Moderate Interactions
These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
What is dilantin used for?
Dilantin, also known as phenytoin, is a medication used in treating people with seizure disorders , also called epilepsy. According to the People's Pharmacy, phenytoin was first discovered in 1908, although it was not used to treat seizure disorders until 1938.
How far apart should I take dilantin?
According to an abstracted article from the University of Maryland, it is important to take Dilantin and foods with calcium or calcium supplements 2 hours apart to promote increased absorption of both Dilantin and calcium. Advertisement.
Can dilantin cause seizure?
Particularly of concern is the serious side effects that may be experienced with decreased absorption of Dilantin caused by concurrent calcium intake from dairy foods; seizure activity may occur if therapeutic Dilantin levels are not maintained in the body.
Does dilantin cause epilepsy?
The oldest anti-epilepsy drug on the market today, Dilantin carries with it many side effects, from folic acid deficiency to recurrent neuro-toxicity. In addition, consumption of some foods, such as milk, for example, should be closely monitored while taking Dilantin, as it may interfere with absorption of Dilantin.
Can you eat whole wheat bread with dilantin?
Enriched wheat foods, such as pasta, whole wheat bread and cereals are also foods to be avoided while taking Dilantin, as they also contain folates that interfere with Dilantin absorption.
Is folate good for dilantin absorption?
As is the case with dairy products, careful monitoring of enriched wheat products is important, and folate supplementation is a beneficial alternative in maintaining a balanced diet as they do not interfere with Dilantin absorption. Advertisement.
Very Important
A change in your diet, medicine, or dosage may be necessary. Promptly consult your doctor or pharmacist.
Are you currently using Dilantin?
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PHENYTOIN Pharmacology: Antiepileptic Drugs
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