Precautions
Medically reviewed on Dec 15, 2017. SMZ-TMP DS are both antibiotics that treat different types of infection caused by bacteria. SMZ-TMP DS is used a combination antibiotic used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia.
What is SMZ TMP DS used to treat?
Generic Name: sulfamethoxazole and trimethoprim (SUL fa meth OX a zole and trye METH oh prim) Brand Name: SMZ-TMP DS. SMZ-TMP DS (sulfamethoxazole and trimethoprim) is a combination antibiotic used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia.
What is the generic name for SMZ-TMP DS?
Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. SMZ-TMP DS will not treat a viral infection such as the common cold or flu.
Can I skip a dose of SMZ-TMP DS?
SMZ-TMP DS side effects. severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling. Common side effects may include:
What are the side effects of SMZ-TMP DS?
What is SMZ-TMP DS?
What should I avoid while using SMZ-TMP DS?
How to prevent kidney stones while taking sulfamethoxazole?
What is Multum's drug information?
Can you take SMZ TMP DS while pregnant?
Can you take SMZ-TMP DS if you have folic acid deficiency?
Can sulfamethoxazole affect results?
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About this website
What kind of antibiotic is SMZ-TMP?
This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections).
What medication should not be taken with SMZ-TMP?
Some products that may interact with this drug include: "blood thinners" (such as warfarin), dofetilide, methenamine, methotrexate. This product may interfere with certain laboratory tests, possibly causing false test results.
Does SMZ-TMP have penicillin in it?
Yes, Bactrim DS contains sulfamethoxazole and trimethoprim. It is in no way related to Penicillin. It is safe to take if you are allergic to Penicillin. Bactrim DS is an antibiotic and belongs to a drug class called sulfonamides.
Is sulfamethoxazole the same as amoxicillin?
Are Augmentin and Bactrim the Same Thing? Augmentin (amoxicillin/clavulanate) and Bactrim (sulfamethoxazole and trimethoprim) are antibiotics used to treat a wide variety of bacterial infections. Augmentin and Bactrim are different types of antibiotics.
What infections does SMZ-TMP treat?
Descriptions. Sulfamethoxazole and trimethoprim combination is used to treat infections including urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery).
What foods should I avoid while taking sulfamethoxazole?
People taking trimethoprim or TMP/SMX should talk with the prescribing doctor before taking any potassium supplements or potassium-containing products, such as No Salt, Salt Substitute, Lite Salt, and even high-potassium foods (primarily fruit). PABA may interfere with the activity of sulfamethoxazole.
What should I avoid while taking Bactrim?
Some products that may interact with this drug include: "blood thinners" (such as warfarin), dofetilide, methenamine, methotrexate. This product may interfere with certain laboratory tests, possibly causing false test results.
How quickly does SMZ TMP work?
How fast does Bactrim (sulfamethoxazole / trimethoprim) work? Bactrim (sulfamethoxazole / trimethoprim) is absorbed by the body and begins to kill bacteria within 1 to 4 hours after taking your dose.
What are the side effects of SMZ TMP?
AdvertisementBlack, tarry stools.blistering, peeling, or loosening of the skin.changes in skin color.chest pain or tightness.cough or hoarseness.general feeling of tiredness or weakness.headache.itching, skin rash.More items...•
How long does sulfamethoxazole stay in your system?
Detectable amounts of sulfamethoxazole and trimethoprim are present in the blood 24 hours after drug administration.
Is Sulfameth trimethoprim a strong antibiotic?
Bottom Line. Sulfamethoxazole/trimethoprim is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly.
What are the most common side effects of Bactrim?
The most common adverse reactions are gastrointestinal disturbances (nausea, vomiting, and anorexia) and allergic skin reactions (such as rash and urticaria). Local reaction, pain and slight irritation on intravenous (IV) administration are infrequent. Thrombophlebitis has been observed.
What is sulfamethoxazole used to treat?
Sulfamethoxazole and trimethoprim combination is used to treat infections including urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery).
Can I take amoxicillin with Sulfameth trimethoprim?
Interactions between your drugs No interactions were found between amoxicillin and trimethoprim.
Is amoxicillin a sulfa drug?
by Drugs.com Amoxicillin belongs to a class of drugs called penicillins. It is a penicillin type antibiotic and it does not have sulfa in it.
Will amoxicillin work for UTI?
As many women (and men) know, the typical treatment for a urinary tract infection (UTI) is an antibiotic. The best antibiotic to take depends on which bacteria is causing the infection; however, amoxicillin is a common treatment.
What is smz tmp ds 800 -160 tab used for? - Answers
Urinary track infection urinary "tract" infection, among other types of skin infections such as staph, yeast etc its basically a very strong antibiotic that covers a wide range of bacteria.
SMZ-TMP DS Oral: Uses, Side Effects, Interactions, Pictures ... - WebMD
Find patient medical information for SMZ-TMP DS oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Smz tmp ds 800 160 | Answers from Doctors | HealthTap
Diagnosed with cellulitis, prescribed cephalexin 500 mg & smz/tmp ds 800 - 160 two months ago, i didn't finish meds, can i finish them now?
SMZ-TMP DS Side Effects: Common, Severe, Long Term - Drugs.com
SMZ-TMP DS Side Effects. Generic name: sulfamethoxazole / trimethoprim Medically reviewed by Drugs.com. Last updated on Jun 9, 2022. Consumer; Professional; FAQ; Note: This document contains side effect information about sulfamethoxazole / trimethoprim. Some of the dosage forms listed on this page may not apply to the brand name SMZ-TMP DS.. For the Consumer
Conditions that SMZ-TMP DS oral Treats - WebMD
Find information about which conditions SMZ-TMP DS oral is commonly used to treat.
How to take SMZ TMP?
How to use SMZ-TMP DS Tablet. Take this medication by mouth, as directed by your doctor, with a full glass of water (8 ounces / 240 milliliters). If stomach upset occurs, take with food or milk. Drink plenty of fluids while taking this medication to lower the unlikely risk of kidney stones forming, unless your doctor advises you otherwise.
What is sulfamethoxazole used for?
It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type).This medication should not be used in ...
Can you take sulfamethoxazole with trimethoprim?
Precautions. Before taking sulfamethoxazole with trimethoprim, tell your doctor or pharmacist if you are allergic to sulfa medications or trimethoprim; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Are you currently using SMZ-TMP DS Tablet?
This survey is being conducted by the WebMD marketing sciences department.
What is sulfamethoxazole used for?
Sulfamethoxazole Trimethoprim is often used to treat urinary tract, skin, respiratory, or digestive tract infections. It may be used for ear infections, kennel cough, coccidiosis, and pneumonia. If this drug is given to dogs long term, it may ...
How does trimethoprim work?
Trimethoprim works similarly, by blocking the production of folic acid at a different stage in it’s development. By combining these two drugs, there is a heightened chance of killing the bacteria without promoting any resistance by the bacteria.
What is the difference between sulfamethoxazole and trimethoprim?
Sulfamethoxazole is an sulfonamide antibiotic that inhibits the growth of bacteria by blocking the production of folic acid, which is essential in making the bacteria’s DNA. Trimethoprim works similarly, by blocking the production of folic acid at a different stage in it’s development.
What are the side effects of sulfamethoxazole?
Sulfamethoxazole Trimethoprim may result in these side effects: 1 Dry eye 2 Loss of appetite 3 Vomiting 4 Diarrhea 5 Fever 6 Anemia 7 Damage to the liver 8 Increase in urination 9 Increase in water intake 10 Swelling of the face 11 Bladder stones
What is the most important information I should know about SMZ-TMP DS (Oral)?
You should not use this medicine if you are allergic to sulfamethoxazole or trimethoprim, or if you have:
What are the side effects of SMZ-TMP DS (Oral)?
Get emergency medical help if you have signs of an allergic reaction (hives, cough, chest pain, shortness of breath, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
What drugs and food should I avoid while taking SMZ-TMP DS (Oral)?
If you use the injection form of this medicine, do not eat or drink anything that contains propylene glycol (an ingredient in many processed foods, soft drinks, and medicines). Dangerous effects could occur.
How to take SMZ-TMP DS (Oral)?
Use SMZ-TMP DS (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
What happens if I overdose on SMZ-TMP DS (Oral)?
Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.
Uses
For the treatment of initial episodes of uncomplicated urinary tract infections due to susceptible strains of the following organisms: Escherichiacoli, Proteus mirabilis, Klebsiella pneumoniae, Enterobacter species and coagulase-negative Staphylococcus species, including S. saprophyticus.
Dosage
The usual oral adult dosage is 100 mg of trimethoprim every 12 hours or 200 mg trimethoprim every 24 hours, each for 10 days.
Side Effects
Pruritus, rash, urticaria, mild GI disturbance (e.g. nausea, vomiting, glossitis, sore mouth); disturbance of liver enzymes, photosensitivity, angioedema, myalgia, headache; hyperkalaemia, hyponatraemia; agranulocytosis.
Toxicity
The oral LD 50 in mice and rats is 2764 mg/kg and >5300 mg/kg, respectively.
Precaution
Patient with actual or potential folate deficiency (e.g. malnourished, chronic anticonvulsant therapy, elderly). Hepatic and renal impairment. Childn (esp those with fragile X chromosome associated with mental retardation). Pregnancy and lactation.
Interaction
May increase concentration of dapsone. Increased elimination and shortened elimination half-life with rifampicin. Increases concentration of phenytoin, digoxin, procainamide, rosiglitazone, repaglinide, zidovudine, zalcitabine, lamivudine. Increased risk of nephrotoxicity with ciclosporin. Potentiates anticoagulant effect of warfarin.
Volume of Distribution
Trimethoprim is extensively distributed into various tissues following oral administration. It distributes well into sputum, middle ear fluid, and bronchial secretions. Trimethoprim distributes efficiently into vaginal fluids, with observed concentrations approximately 1.6-fold higher than those seen in the serum.
What is sulfamethoxazole used for?
Sulfamethoxazole and trimethoprim combination is used to treat infections including urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery). This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. This type of pneumonia occurs more commonly in patients whose immune systems are not working normally, including cancer patients, transplant patients, and patients with acquired immune deficiency syndrome (AIDS).
Does sulfamethoxazole work for colds?
Sulfamethoxazole and trimethoprim combination is an antibiotic. It works by eliminating the bacteria that cause many kinds of infections. This medicine will not work for colds, flu, or other virus infections. This medicine is available only with your doctor's prescription.
What is sulfamethoxazole used for?
It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type).This medication should not be used in children ...
How to use sulfamethoxazole DS?
How to use Sulfamethoxazole-TMP DS oral. Shake this medication well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Take this medication by mouth, as directed by your doctor, with a full glass of water (8 ounces / 240 milliliters).
How to report sulfamethoxazole side effects?
You may report side effects to Health Canada at 1-866-234-2345. Precautions. Before taking sulfamethoxazole with trimethoprim, tell your doctor or pharmacist if you are allergic to sulfa medications ...
Can you take sulfamethoxazole with trimethoprim?
Precautions. Before taking sulfamethoxazole with trimethoprim, tell your doctor or pharmacist if you are allergic to sulfa medications or trimethoprim; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
What is the name of the drug sulfamethoxazole?
Sulfamethoxazole/trimethoprim- oral. Pronunciation. (sull-fuh-meth-OX-uh-zole/try-METH-oh-prim) Brand name (s) Bactrim , Septra. Uses. This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). ...
What medical conditions can you have before taking trimethoprim?
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease. liver disease. certain blood disorders (such as porphyria, anemia due to folate vitamin deficiency) history of blood disorders caused by trimethoprim or sulfa medications.
Can you take sulfamethoxazole with trimethoprim?
Before taking sulfamethoxazole with trimethoprim, tell your doctor or pharmacist if you are allergic to sulfa medications or trimethoprim; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
What is TMP/SMX used for?
Trimethoprim/sulfamethoxazole ( TMP/SMX ), also known as co-trimoxazole among other names, is a combination antibiotic used to treat a variety of bacterial infections. It consists of one part trimethoprim to five parts sulfamethoxazole. It is used for urinary tract infections, methicillin-resistant Staphylococcus aureus (MRSA) skin infections, travelers' diarrhea, respiratory tract infections, and cholera, among others. It may be used both to treat and prevent pneumocystis pneumonia and toxoplasmosis in people with HIV/AIDS and other causes of immunosuppression. It can be given by mouth or intravenously.
When was TMP/SMX first sold?
TMP/SMX was first sold in 1974. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2019, it was the 100th most commonly prescribed medication in the United States, with more than 6 million prescriptions.
Why is trimethoprim given in a one to five ratio?
Trimethoprim and sulfamethoxazole have a greater effect when given together than when given separately, because they inhibit successive steps in the folate synthesis pathway. They are given in a one-to-five ratio in their tablet formulations so that when they enter the body their concentration in the blood and tissues is roughly one-to-twenty — the exact ratio required for a peak synergistic effect between the two.
What are the contraindications for sulphonamides?
Contraindications include the following: Known hypersensitivity to trimethoprim , sulphonamides or any other ingredients in the formulations. Pregnancy – especially in the period prior to birth. Severe hepatic failure, marked liver parenchymal damage or jaundice.
How does sulfamethoxazole affect bacteria?
Sulfamethoxazole, a sulfonamide, induces its therapeutic effects by interfering with the de novo (that is, from within the cell) synthesis of folate inside microbial organisms such as protozoa , fungi and bacteria. It does this by competing with p -aminobenzoic acid (PABA) in the biosynthesis of dihydrofolate.
What is the abbreviation for trimethoprim?
Trimethoprim/sulfamethoxazole may be abbreviated as SXT, TMP-SMX, TMP-SMZ, or TMP-sulfa.
Which is more effective in clearing co-trimoxazole from plasma?
Haemodialysis, which is moderately effective in clearing co-trimoxazole from the plasma.
What are the side effects of taking sulfamethoxazole?
Check with your doctor immediately if any of the following side effects occur while taking sulfamethoxazole / trimethoprim: More common. Black, tarry stools. blistering, peeling, or loosening of the skin. changes in skin color. chest pain. chills.
Does sulfamethoxazole need immediate medical attention?
Side effects not requiring immediate medical attention. Some side effects of sulfamethoxazole / trimethoprim may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
What is SMZ-TMP DS?
SMZ-TMP DS (sulfamethoxazole and trimethoprim) is a combination antibiotic used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia.
What should I avoid while using SMZ-TMP DS?
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.
How to prevent kidney stones while taking sulfamethoxazole?
Drink plenty of fluids to prevent kidney stones while you are using this medicine. Sulfamethoxazole and trimethoprim doses are based on weight in children. Use only the recommended dose when giving this medicine to a child. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve.
What is Multum's drug information?
Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
Can you take SMZ TMP DS while pregnant?
You should not take SMZ-TMP DS if you are pregnant or breastfeeding.
Can you take SMZ-TMP DS if you have folic acid deficiency?
You should not use SMZ-TMP DS if you have severe liver disease, kidney disease that is not being monitored, anemia caused by folic acid deficiency, if you take dofetilide, or if you have had low platelets caused by using trimethoprim or a sulfa drug.
Can sulfamethoxazole affect results?
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using sulfamethoxazole and trimethoprim.