Precautions
Check with your doctor immediately if any of the following side effects occur while taking modafinil: Get emergency help immediately if any of the following symptoms of overdose occur while taking modafinil: Some side effects of modafinil may occur that usually do not need medical attention.
What should I do if I have side effects from modafinil?
Modafinil is known to have a slight effect on the liver, but this is reversible. Some patients who have taken Modafinil for extended periods of time showed mild, reversible liver damage which returned to normal once they stopped taking the drug.
Is modafinil bad for Your Liver?
In the Journal of American Medical Association, Dr. Nora D. Volkow, Director of the National Institute on Drug Abuse (NIDA), said that modafinil has the same effect on the dopamine centers of the brain as cocaine, methamphetamines and amphetamines.
How does modafinil affect the brain?
Abuse of Modafinil may also result in permanent physical damage under extreme conditions involving regular abuse lasting over one year. It is usually a safe drug to use, though some rare cases have been reported where the patients experienced injuries unrelated to their prescribed daily dose. Is Modafinil Bad For Your Heart?
Can modafinil be abused?
Does modafinil damage the brain?
Thus, modafinil could induce changes in plasticity or behavioral rigidity, and potentially damage WM, logical thinking and decision making. It has been reported that prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons (Rao et al., 2007).
Is modafinil bad for your health?
Modafinil is generally considered safe for most people, with minor side effects such as headache, nausea, insomnia, anxiety, and dizziness. However, it may be associated with rare life-threatening skin conditions or rare psychiatric conditions [4][5].
Is modafinil bad for your heart?
Modafinil substantially perturbs autonomic cardiovascular regulation by increase in heart rate and blood pressure. Autonomic changes of this magnitude encourage caution in use of modafinil in patients with cardiovascular disease.
Who should not take modafinil?
You should not use modafinil if you have ever had an allergic reaction or skin rash while taking modafinil or armodafinil (Nuvigil). Modafinil can cause skin reactions that may be severe enough to need treatment in a hospital.
Is it bad to take modafinil everyday?
The recommended dose for modafinil is 200mg taken once daily [23]. Modafinil has been found to be well-tolerated, with a low incidence of adverse effects and low potential for abuse [24].
Is modafinil hard on liver?
Both modafinil and armodafinil are associated with a low rate of serum aminotransferase elevations during therapy, but they have not been implicated in cases of clinically apparent acute liver injury.
What should I avoid while taking modafinil?
Notes for Consumers: Limit excessive caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Modafinil. Also avoid medicines containing additional Caffeine whenever possible.
What are the benefits of modafinil?
The drug modafinil was developed to treat narcolepsy (excessive sleeping), but it is widely used off-licence as a 'smart drug' to promote cognitive enhancement, where qualities such as alertness and concentration are desired to assist someone with, for example, exam preparation.
How long is modafinil in your system?
The normal half-life of modafinil in humans is between 12 to 15 hours [4].
Is modafinil good for anxiety?
Modafinil has a variety of effects on anxiety in humans and anxiety-like behaviour in animal models. Some studies have shown anxiety generating (anxiogenic) effects in humans, while others show anxiety reducing (anxiolytic) effects.
Does modafinil cause weight gain?
Conclusions: Modafinil treatment resulted in a significant weight loss in this patient, possibly due to reducing clozapine-associated fatigue. Randomized placebo-controlled trials are necessary to evaluate the safety and efficacy of modafinilfor clozapine-associated weight gain.
How does modafinil make you feel?
In easy terms, Modafinil is a brain stimulant. Basically, it interferes with the levels of chemical messengers of the brain & causes stimulation. As a result, you feel less sleepy and more energetic. You feel like having superhuman powers.
Does modafinil weaken immune system?
It can be applied as an anti-psychotic or anti-fatigue agent. However, the waking mechanism of modafinil is yet to be fully revealed. Recent studies reported that modafinil may be subject to abuse and addiction. In addition prolonged sleeplessness induces stress responses and impairs immune function.
How much modafinil is too much?
Although the maximum recommended daily dose of modafinil is 400 mg, higher doses have been used. There are some patients in whom adequate control of sleepiness may require a slightly higher dose than 400 mg (400 mg in the am and 200 mg in the early afternoon).
Does modafinil cause weight gain?
Conclusions: Modafinil treatment resulted in a significant weight loss in this patient, possibly due to reducing clozapine-associated fatigue. Randomized placebo-controlled trials are necessary to evaluate the safety and efficacy of modafinilfor clozapine-associated weight gain.
Does modafinil work long term?
Conclusions: Modafinil is effective for the long-term treatment of EDS associated with narcolepsy and significantly improves perceptions of general health. Modafinil is well tolerated, with no evidence of tolerance developing during 40 weeks of treatment.