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what are the different types of insulin

by Lindsey Batz Published 2 years ago Updated 1 year ago
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What Type of Insulin Is Best for My Diabetes?

Type of Insulin & Brand Names Onset Peak Duration Role in Blood Sugar Management
Lispro ( Humalog) 15-30 min. 30-90 min 3-5 hours Rapid-acting insulin covers insulin need ...
Aspart ( Novolog) 10-20 min. 40-50 min. 3-5 hours Rapid-acting insulin covers insulin need ...
Glulisine ( Apidra) 20-30 min. 30-90 min. 1-2 1/2 hours Rapid-acting insulin covers insulin need ...
Sep 15 2022

The 5 types of insulin are:
  • rapid-acting insulin.
  • short-acting insulin.
  • intermediate-acting insulin.
  • mixed insulin.
  • long-acting insulin.

Full Answer

What are the best brands of insulin?

Some of the best insulin pumps

  • Medtronic MiniMed 630G System. This model from Medtronic comes with an optional CGM so a person can also monitor their blood sugar levels using the same device.
  • Medtronic MiniMed 770G System. This alternative device from Medtronic is suitable for people with type 1 diabetes aged 2 and older.
  • Omnipod Dash. ...
  • t:slim X2. ...

Which type of insulin has the longest duration of action?

NPH insulin has an onset of 1-2 hours, a peak of 6-12 hours, and a duration of 18 hours Long acting insulin Lantus insulin has an onset of 1 hour, no peak and a duration of 24 hours Humalog, Novolog, and Lispro Rapid acting insulin with an onset of 15 minutes a peak of 30 to 90 minutes, and a duration of 4-5 hours Regular insulin

What are the alternatives to insulin?

They include acetaminophen and NSAIDs, such as aspirin and ibuprofen, as well as some topical NSAID creams. A study in the Canadian Medical Association Journal looked at 40 randomized controlled trials of more than 5,100 adults and their post-op pain.

What is the typical dose of insulin?

In patients with type 2 diabetes, marked obesity, and insulin resistance, total daily insulin doses of 200 to 300 units are often required. In this setting, management for most patients includes a total of 1.0 to 2.0 units of insulin per kilogram per day; thus, in very obese patients, a larger total dose is required.

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What are the 3 types of insulin?

There are three main groups of insulins: Fast-acting, Intermediate-acting and Long-acting insulin.

What are the names of different insulin?

Injectable Insulin MedicationsMedication name: Insulin glulisine (Apidra®) ... Medication name: Insulin aspart (Novolog®) ... Medication name: Insulin lispro U-100/U-200 (Humalog®) ... Medication name: Regular insulin (Novolin R, Humulin R) ... Medication name: NPH insulin (Novolin N, Humulin N)More items...•

What is the most common insulin?

Insulin is available in different strengths; the most common is U-100.

What are the six types of insulin?

There are six main types of insulin available.Rapid-acting: These include Apidra, Humalog, and Novolog. ... Regular (short-acting): These include Humulin R and Novolin R. ... Intermediate-acting: These include Humulin N and Novolin N. ... Long-acting: These include Levemir, Lantus, Semglee, and Tresiba.More items...•

What are the 4 main types of insulin?

Types of insulinrapid-acting insulin.short-acting insulin.intermediate-acting insulin.mixed insulin.long-acting insulin.

What is the most common insulin for type 2 diabetes?

Initial insulin dose — When insulin is started for type 2 diabetes, health care providers usually recommend "basal" insulin; this means taking intermediate-acting and/or long-acting forms of insulin to keep blood sugar controlled throughout the day.

What is the best insulin to take?

What Type of Insulin Is Best for My Diabetes?Type of Insulin & Brand NamesOnsetPeakInsulin glargine (Basaglar, Lantus, Toujeo)1-1 1/2 hoursNo peak time. Insulin is delivered at a steady level.Insulin detemir (Levemir)1-2 hours6-8 hoursInsulin degludec (Tresiba)30-90 min.No peak timePre-Mixed*16 more rows•Aug 25, 2022

What is the name of the new insulin?

INDIANAPOLIS , June 15, 2020 /PRNewswire/ -- The U.S. Food and Drug Administration (FDA) has approved Lyumjev™ (insulin lispro-aabc injection, 100 units/mL and 200 units/mL), Eli Lilly and Company's (NYSE: LLY) new rapid-acting insulin indicated to improve glycemic control in adults with type 1 and type 2 diabetes.

How long can a diabetic go without insulin?

In the worst-case scenario, just how long would we be able to hang on without it? Conventional wisdom says the answer is roughly 3 to 4 days.

How do I know which insulin to use?

You will need to calculate how much carbohydrate you will eat, and take a dose of insulin that matches the food. A high blood sugar correction bolus insulin dose to bring your blood sugar back into the target range.

What is the name of insulin for diabetes?

Different Types of InsulinUsual Action TimesGeneric NameProductWhen to takeRapid-actingaspart glulisine lisproNovolog Apidra HumalogShort-actingRegular (R)Humulin N Novolin RBackground Insulin3 more rows

What are the 3 short-acting insulins?

Three common rapid-acting insulins are: Aspart (marketed as NovoLog, Fiasp (or faster aspart), and the NovoLog FlexPen) Lispro (marketed as Humalog, Admelog, and the Humalog KwikPen) Glulisine (marketed as Apidra and the Apidra SoloStar Pen)

What is the best insulin?

What Type of Insulin Is Best for My Diabetes?Type of Insulin & Brand NamesOnsetPeakLong-ActingInsulin glargine (Basaglar, Lantus, Toujeo)1-1 1/2 hoursNo peak time. Insulin is delivered at a steady level.Insulin detemir (Levemir)1-2 hours6-8 hoursInsulin degludec (Tresiba)30-90 min.No peak time16 more rows•Aug 25, 2022

Which insulin is best for high blood sugar?

Long, ultra-long or intermediate-acting insulin helps the body use this glucose and keeps glucose levels from rising too high. Examples of these insulins are glargine (Lantus, Toujeo, others), detemir (Levemir), degludec (Tresiba) and NPH (Humulin N, Novolin N, Novolin ReliOn Insulin N).

What are the 3 short-acting insulins?

Three common rapid-acting insulins are: Aspart (marketed as NovoLog, Fiasp (or faster aspart), and the NovoLog FlexPen) Lispro (marketed as Humalog, Admelog, and the Humalog KwikPen) Glulisine (marketed as Apidra and the Apidra SoloStar Pen)

What is the name of the new insulin?

INDIANAPOLIS , June 15, 2020 /PRNewswire/ -- The U.S. Food and Drug Administration (FDA) has approved Lyumjev™ (insulin lispro-aabc injection, 100 units/mL and 200 units/mL), Eli Lilly and Company's (NYSE: LLY) new rapid-acting insulin indicated to improve glycemic control in adults with type 1 and type 2 diabetes.

Characteristics of Insulin

Insulins are categorized by differences in: 1. Onset (how quickly they act) 2. Peak (how long it takes to achieve maximum impact) 3. Duration (how...

Intermediate-Acting Insulin

1. Is absorbed more slowly, and lasts longer 2. Is used to control the blood sugar overnight, while fasting and between meals

For Information About, See These Sections

1. Insulin administration 2. Designing an insulin regimen 3. Calculating your insulin dose 4. Intensive insulin therapy 5. Insulin pump therapy 6....

What are the different types of insulin?

Types of Insulin. There are three main groups of insulins: Fast-acting, Intermediate-acting and Long-acting insulin. Fast-acting insulin: Is absorbed quickly from your fat tissue (subcutaneous) into the bloodstream. Is used to control the blood sugar during meals and snacks and to correct high blood sugars. Includes:

How are insulins categorized?

Insulins are categorized by differences in: Onset (how quickly they act) Peak (how long it takes to achieve maximum impact) Duration (how long they last before they wear off) Concentration (Insulins sold in the U.S. have a concentration of 100 units per ml or U100. In other countries, additional concentrations are available.

What is insulin analog?

Human Insulin and Insulin Analogs are available for insulin replacement therapy. Insulins also are classified by the timing of their action in your body – specifically, how quickly they start to act, when they have a maximal effect and how long they act.Insulin analogs have been developed because human insulins have limitations when injected ...

How long does insulin take to work?

Includes: NPH Human Insulin which has an onset of insulin effect of 1 to 2 hours, a peak effect of 4 to 6 hours, and duration of action of more than 12 hours.

How long does insulin detemir last?

The insulin effect plateaus over the next few hours and is followed by a relatively flat duration of action that lasts 12-24 hours for insulin detemir and 24 hours for insulin glargine.

What is the difference between pre-mixed insulin and pre-mixed insulin?

Very small doses will have an earlier peak effect and shorter duration of action, while higher doses will have a longer time to peak effect and prolonged duration. Pre-Mixed Insulin which is NPH pre-mixed with either regular human insulin or a rapid- acting insulin analog. The insulin action profile is a combination of the short ...

How long does it take for insulin to peak?

Regular Human Insulin which has an onset of action of 1/2 hour to 1 hour, peak effect in 2 to 4 hours , and duration of action of 6 to 8 hours. The larger the dose of regular the faster the onset of action, but the longer the time to peak effect and the longer the duration of the effect. Intermediate-acting insulin:

How are insulins categorized?

Insulins are categorized by differences in: Onset (how quickly they act) Peak (how long it takes to achieve maximum impact) Duration (how long they last before they wear off) Concentration (Insulins sold in the U.S. have a concentration of 100 units per ml or U100. In other countries, additional concentrations are available.

What is insulin analog?

Human Insulin and Insulin Analogs are available for insulin replacement therapy. Insulins also are classified by the timing of their action in your body – specifically, how quickly they start to act, when they have a maximal effect and how long they act. Insulin analogs have been developed because human insulins have limitations when injected ...

Why are insulin analogs used?

Insulin analogs have been developed because human insulins have limitations when injected under the skin. In high concentrations, such as in a vial or cartridge, human (and also animal insulin) clumps together. This clumping causes slow and unpredictable absorption from the subcutaneous tissue and a dose-dependent duration of action (i.e. the larger dose, the longer the effect or duration). In contrast, insulin analogs have a more predictable duration of action. The rapid acting insulin analogs work more quickly, and the long acting insulin analogs last longer and have a more even, “peakless” effect.

How long does insulin detemir last?

The insulin effect plateaus over the next few hours and is followed by a relatively flat duration of action that lasts 12-24 hours for insulin detemir and 24 hours for insulin glargine.

How long does it take for insulin to work?

Regular Human Insulin which has an onset of action of 1/2 hour to 1 hour, peak effect in 2 to 4 hours, and duration of action of 6 to 8 hours. The larger the dose of Regular, the faster the onset of action, but the longer the time to peak effect and the longer the duration of the effect.

Where is insulin injected?

Insulin is usually injected into the fatty tissue just under the skin. This is also called subcutaneous tissue. See a table of insulin action below and a graphic illustration of onset of action, peak effect and duration of action of the different insulins.

When was insulin first available?

Insulin has been available since 1925 . It was initially extracted from beef and pork pancreases. In the early 1980’s, technology became available to produce human insulin synthetically. Synthetic human insulin has replaced beef and pork insulin in the US. And now, insulin analogs are replacing human insulin.

What are the 6 different types of insulin?

You may need more insulin coverage at mealtimes, overnight, or throughout the entire day. Currently, there are 5 types of injectable insulins and 1 inhaled insulin.

How are these insulins used?

Some people with diabetes may only need 1 type of insulin, while others may need multiple types to manage their blood sugar. Your doctor will help choose an insulin regimen that’s right for you.

Who uses insulin?

Insulin treatment is common in people with diabetes. These 3 types of diabetes can be managed with insulin:

How do you inject insulin?

When injecting insulin, always make sure you’re giving yourself the correct insulin type and dosage according to your prescription. Injecting too much insulin can lead to low blood sugar (hypoglycemia) and can turn into a medical emergency quickly (signs of hypoglycemia include confusion, lightheadedness, sweating, anxiety, and shakiness). Also, never mix or dilute insulin unless your doctor tells you to, and never use expired insulin.

What is the name of the insulin that is short acting and quick acting?

Background insulins are: NPH (intermediate-acting and cloudy looking), Glargine and detemir insulin (long-acting and clear looking – also called “basal” insulin because they have no peak) Mealtime Insulin (rapid and short-acting) Helps control glucose after eating a meal or snack. Take before meals.

What is the strength of insulin?

Insulin is made in different strengths. Most people use a strength called U-100. Insulin’s come in several different types. Some are faster-working and last for a shorter period of time while others are slower-working and last for a longer period of time.

What is mealtime insulin?

Mealtime insulins are: Lispro, aspart, glulisin e insulin (rapid-acting and clear looking) and Regular insulin (short-acting and clear looking) Premixed insulin is a combination of background and mealtime insulin.

What is the medication used to manage type 1 diabetes?

Insulin is the medication used to manage type 1 and, in some cases, type 2 diabetes. There are several things you should know about insulin. Insulin is a hormone that lowers glucose in your blood. Injected or inhaled insulin replaces what the body makes naturally.

Can you take insulin if you have type 1 diabetes?

People with type 1 diabetes must take insulin to survive. About half the people with type 2 diabetes will need to take insulin at some point in their lives. Taking insulin doesn’t mean you’ve failed; your body may just need extra help. Insulin is safe and one of the most effective ways to lower blood glucose.

Do different companies make different types of insulin?

Different companies make different types of insulin. Always use the same brand and type of insulin that your provider has prescribed.

Does Humalog 75/25 contain insulin?

Humalog 75/25, Humalog 50/50 and Novolog 70/30 also contain some slower-acting insulin along with some rapid-acting (lispro and aspart) insulin in one bottle.

How many different types of insulin are there?

Although there are four main types of insulin, there are far more prescription brands that offer the medication in its main forms. These brands may vary by the type of insulin, dosing, and how it is delivered, among other factors. Here’s an overview of the different brands and insulin products available:

What do you need to know about insulin?

Insulin Chart: What You Need to Know About Insulin Types and Timing. Medically reviewed by Deborah Weatherspoon, Ph.D., R.N., CRNA — Written by Heather Grey — Updated on March 4, 2019. If you have type 2 diabetes, your doctor might prescribe insulin therapy to help manage your blood sugar levels. Insulin is a hormone that’s produced in the pancreas.

Why can't you take insulin in pill form?

Insulin can’t be taken in pill-form because your digestive system would break it down in the same way that you digest food. That means the insulin wouldn’t make it to your bloodstream where it’s needed. Depending on your health history, your doctor might prescribe one type of insulin or multiple types of insulin.

Why do people with type 2 diabetes need insulin?

It regulates blood sugar levels and allows your body to convert sugar into energy. People with type 2 diabetes are still able to make insulin, but the body doesn’t use it effectively. That’s why some people with type 2 diabetes need to take prescription insulin.

What factors should be considered when taking insulin?

For example, your doctor may consider: your blood glucose. levels. how long you’ve lived. with type 2 diabetes. any current medications. you take.

Does insulin need to change over time?

your lifestyle and. overall health. your insurance coverage. Over time, your insulin needs may change and your doctor may suggest trying something new. It’s normal for your treatment plan to shift over time. If you have questions about why your doctor recommends a certain type of insulin, talk to them.

What is the most commonly used type of insulin?

The first source of insulin is insulin which is artificially grown in labs. This type of insulin, called human insulin is the most commonly used type.

What is the second type of insulin?

The second type of insulin is animal insulin, which is taken from the pancreas of animals. Analogue insulin is a form of human insulin in which the molecules are chemically altered so that the insulin works in a particular way.

What is mixed insulin?

Mixed or combination insulins are where a shorter acting insulin is combined with a longer acting insulin. On the plus side, this can mean less injections and can help to make dosages simpler. The disadvantage though, is that premixed insulins allow for less flexibility with tailoring your doses.

How is insulin categorised?

From rapid acting to long acting, from animal insulin through to analogue insulins. Insulin can be categorised by how the insulin is derived and how quickly it acts.

Where does animal insulin come from?

Animal insulin is derived from the pancreas of cows and pigs: Animal insulin tends not to be prescribed as a first choice of insulin but should be available if requested. Some people may choose to go onto animal insulin. Different types of insulin can have different durations of effectiveness.

Is human insulin a lab made insulin?

Instead, human insulin is a laboratory made insulin. Analogue insulin is a type of lab grown human insulin which is modified to affect how quickly or slowly it acts. Analogue insulin. Animal insulin.

Who makes hypurin insulin?

Hypurin: Hypurin insulins are animal insulins produced by Wockhardt UK . They make short acting, intermediate and long acting insulins and are available in beef or pork insulin forms.

How long does insulin last?

Intermediate, long-acting, and ultra-long-acting insulins are used to replace basal insulin with the goal of keeping blood glucose levels consistent throughout the day and night. They begin working about two hours after injection and are released slowly, peaking at four to eight hours after injection, and lasting for at least 24 hours. 7 

How does the pancreas produce insulin?

The pancreas produces insulin in two different ways: 5  1 Basal insulin (sometimes called background insulin) regulates glucose levels between meals and is released 24 hours a day, whether or not a person eats. 2 Bolus insulin is released by the pancreas in direct response to the ingestion of food in order to manage the rise in blood glucose that immediately follows.

What is the difference between NPH and insulin?

Unlike the clear fluid that characterizes short- and rapid-acting insulins, NPH has a cloudy consistency caused by crystals of insulin in the solution.

Why do you use bolus insulin before eating?

Both types are used to replace the natural bolus insulin produced by the pancreas. Because they begin to work quickly, they're used just before meals or snacks to offset the immediate rise in glucose levels that will occur from eating. 7 

Why is insulin important?

Its job is to help the body use or store the glucose that's derived from carbohydrates in the diet. Glucose is necessary for every bodily function; it circulates in the bloodstream and is taken up by cells for energy. 3 .

How long does it take for basal insulin to release?

Basal insulin (sometimes called background insulin) regulates glucose levels between meals and is released 24 hours a day, whether or not a person eats.

What is the purpose of supplemental insulin?

Supplemental insulin—a manufactured version of the hormone naturally produced by cells in the pancreas to regulate levels of glucose (sugar) in the blood— is vital for controlling type 1 diabetes (diabetes mellitus). It's also a treatment for gestational diabetes, a temporary form of the disease that can develop during pregnancy.

What are the differences between insulins?

Insulin analogues are better than standard human insulin at mimicking natural insulin release. They have a more predictable duration of action and more reliable absorption .

What else should I know about insulin?

Our insulin requirements vary depending on the food we eat, how much activity we do, our general and mental health, how much we currently weigh, and our age.

How is insulin administered?

Insulin is most commonly administered subcutaneously (under the skin) and there are three main delivery methods:

What are the side effects of insulin?

One of the most common side effects of insulin is hypoglycemia (also called low blood sugar ).

How long does insulin last for?

Insulin is easily broken down by extreme temperatures, which means you need to be careful if you live in a part of the U.S. that gets very hot in summer, or very cold in winter.

Why is hypoglycemia common?

Hypoglycemia is relatively common because insulin requirements can vary depending on the food you eat, exercise you do, and how well you are. Hyperglycemia (high blood sugar levels) from too low an insulin dose can also occasionally occur. Other common side effects include:

How many units per ml of insulin is there?

Most insulin in the U.S. is sold as a concentration of 100 units per ml (U100). However, there are currently four concentrated products on the market: Humulin R (human insulin) which has a 500 units per ml (U500) strength available. Humalog (insulin lispro) which has a 200 units per ml (U200) strength available.

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